Metabolism, Aging and Disease

Mitochondria, Metabolism and Disease

Mitochondria

Metabolism

Toxicology

Mitochondria-targeted therapeutics

Ageing

Pharmacology


Research lines

Mitochondrial remodeling in aging and lifestyle-diseases

Mitochondrial toxicity of pharmaceuticals and environmental polutants

Mitochondria-targeted therapeutics and protection

Overview

Mitochondria are critical organelles in the context of cell physiology. Mitochondria are the cell energy powerplants by producing most of the chemical energy and play an important role in cell death and quality control processes. Since mitochondria are also active players in cellular redox and calcium homeostasis, as well as in intermediate metabolism, the general objective of our research group is to provide insights into the role of mitochondrial alterations in metabolism, redox signaling and stress responses in chemical toxicology, cancer, cardiovascular and hepatic diseases, aging, and stem cell differentiation.

We investigate whether intrinsic, pharmacological or non-pharmacological (e.g. by exercise) regulation of mitochondrial biogenesis/metabolism and quality control alters (cancer) reduces organ injury during distinct pathologies or as caused by the toxicity of different xenobiotics. The mechanisms of mitochondrial biogenesis and regulation by molecules such as resveratrol or proteins such as sirtuins are important scientific questions. In the same context, another important aim is to investigate how regulation of mitochondrial activity impacts (cancer) stem cell differentiation.

Different molecules or pathologies activate mitochondrial stress/toxicity responses, affecting the cell phenotype and often organ survival. Among the different mitochondrial toxicants, we investigate anti-cancer agents such as anthracyclines, anti-estrogens or retinoids. Similarly, we developed a library of distinct mitochondrial-directed molecules to investigate their potential as future anti-neoplastic or antioxidant agents. In the framework of mitochondrial alterations during the aging process, another objective of our group is to investigate the role of bone mitochondrial bioenergetics impairment and mitochondrial/peroxisomal fatty acid beta-oxidation unbalance on estrogen-deprivation-induced menopause.

Publications

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Information about journal articles, updated at 26-06-2022, from platform CIÊNCIAVITAE.

Mitochondrial and metabolic remodeling in human skin fibroblasts in response to glucose availability

Pinho, Sónia A.; Costa, Cláudio F.; Deus, Cláudia M.; Pinho, Sonia L.C.; Miranda-Santos, Inês; Afonso, Gonçalo; Bagshaw, Olivia; et al, 2022. The FEBS Journal. 2022. http://dx.doi.org/10.1111/febs.16413 . 10.1111/febs.16413 . published The FEBS Journal

Shaping of Hepatic Ischemia/Reperfusion Events: The Crucial Role of Mitochondria

João S. Teodoro; Rui T. Da Silva; Ivo F. Machado; Arnau Panisello-Roselló; Joan Roselló-Catafau; Anabela P. Rolo; Carlos M. Palmeira, 2022. Cells. 688 - 688. 4. 11. 2022. https://doi.org/10.3390/cells11040688 . 10.3390/cells11040688 . Cells

PEG35 as a Preconditioning Agent against Hypoxia/Reoxygenation Injury

Rui Teixeira da Silva; Ivo F. Machado; João S. Teodoro; Arnau Panisello-Roselló; Joan Roselló-Catafau; Anabela P. Rolo; Carlos M. Palmeira, 2022. International Journal of Molecular Sciences. 1156 - 1156. 3. 23. 2022. https://doi.org/10.3390/ijms23031156 . 10.3390/ijms23031156 . International Journal of Molecular Sciences

IGL-2 as a Unique Solution for Cold Static Preservation and Machine Perfusion in Liver and Mitochondrial Protection

Rui Teixeira Da Silva; Raquel G. Bardallo; Emma Folch-Puy; Teresa Carbonell; Carlos M. Palmeira; Constantino Fondevila; René Adam; Joan Roselló-Catafau; Arnau Panisello-Roselló, 2022. Transplantation Proceedings. 73 - 76. 1. 54. 2022. https://doi.org/10.1016/j.transproceed.2021.10.008 . 10.1016/j.transproceed.2021.10.008 . Transplantation Proceedings

The Use of a Single, Novel Preservation Solution in Split Liver Transplantation and Hypothermic Oxygenated Machine Perfusion

2022. Transplantation. e187 - e188. 3. 106. 2022. published Transplantation

Cytoskeleton alterations in non-alcoholic fatty liver disease

Pessoa, João; Teixeira, José, 2022. Metabolism. 128. 2022. http://dx.doi.org/10.1016/j.metabol.2021.155115 . 10.1016/j.metabol.2021.155115 . Metabolism

Mitochondriotropic antioxidant based on caffeic acid AntiOxCIN4 activates Nrf2-dependent antioxidant defenses and quality control mechanisms to antagonize oxidative stress-induced cell damage

Amorim, Ricardo; Cagide, Fernando; Tavares, Ludgero C.; Simões, Rui F.; Soares, Pedro; Benfeito, Sofia; Baldeiras, Inês; et al, 2022. Free Radical Biology and Medicine. 119 - 132. 179. 2022. http://dx.doi.org/10.1016/j.freeradbiomed.2021.12.304 . 10.1016/j.freeradbiomed.2021.12.304 . Free Radical Biology and Medicine

Redox profiles of amyotrophic lateral sclerosis lymphoblasts with or without known SOD1 mutations

Teresa Cunha-Oliveira; Daniela Franco Silva; Luis Segura; Inês Baldeiras; Ricardo Marques; Tatiana Rosenstock; Paulo J. Oliveira; Filomena S. G. Silva, 2022. European Journal of Clinical Investigation. 2022. https://doi.org/10.1111/eci.13798 . 10.1111/eci.13798 . European Journal of Clinical Investigation

Modulation of cellular redox environment as a novel therapeutic strategy for Parkinson's disease

Cláudia M. Deus; José Teixeira; Nuno Raimundo; Paolo Tucci; Fernanda Borges; Luciano Saso; Paulo J. Oliveira, 2022. European Journal of Clinical Investigation. 2022. https://doi.org/10.1111/eci.13820 . 10.1111/eci.13820 . European Journal of Clinical Investigation

Mitochondrial and metabolic remodelling in human skin fibroblasts in response to glucose availability

Sónia A. Pinho; Cláudio F. Costa; Cláudia M. Deus; Sonia L. C. Pinho; Inês Miranda-Santos; Gonçalo Afonso; Olivia Bagshaw; et al, 2022. The FEBS Journal. 2022. https://doi.org/10.1111/febs.16413 . 10.1111/febs.16413 . The FEBS Journal

Mitochondrial and metabolic dysfunction in ageing and age-related diseases

Amorim, João A.; Coppotelli, Giuseppe; Rolo, Anabela P.; Palmeira, Carlos M.; Ross, Jaime M.; Sinclair, David A., 2022. Nature Reviews Endocrinology. 2022. http://dx.doi.org/10.1038/s41574-021-00626-7 . 10.1038/s41574-021-00626-7 . Nature Reviews Endocrinology

Evaluation of 6-Hydroxydopamine and Rotenone In Vitro Neurotoxicity on Differentiated SH-SY5Y Cells Using Applied Computational Statistics

Rui F. Simões; Paulo J. Oliveira; Teresa Cunha-Oliveira; Francisco B. Pereira, 2022. International Journal of Molecular Sciences. 3009 - 3009. 6. 23. 2022. https://doi.org/10.3390/ijms23063009 . 10.3390/ijms23063009 . International Journal of Molecular Sciences

The heart of FOIE GRAS and mtFOIE GRAS: fundamental and clinical investigation for training and innovation in non-alcoholic fatty liver disease

Paulo J Oliveira, 2022. European Heart Journal. 2022. https://doi.org/10.1093/eurheartj/ehab399 . 10.1093/eurheartj/ehab399 . European Heart Journal

Bioenergetic remodeling in the pathophysiology and treatment of nonalcoholic fatty liver disease

Anabela Marisa Azul; Martin Winter; Daniel Silva; Liljana Georgievska; Paulo J. Oliveira, 2022. European Journal of Clinical Investigation. 2022. https://doi.org/10.1111/eci.13749 . 10.1111/eci.13749 . European Journal of Clinical Investigation

The Role of Glucosinolates from Cruciferous Vegetables (Brassicaceae) in Gastrointestinal Cancers: From Prevention to Therapeutics

Catarina Melim; Maria R. Lauro; Isabel M. Pires; Paulo J. Oliveira; Célia Cabral, 2022. Pharmaceutics. 2022. https://doi.org/10.3390/pharmaceutics14010190 . 10.3390/pharmaceutics14010190 . Pharmaceutics

Effect of a Novel Hydroxybenzoic Acid Based Mitochondria Directed Antioxidant Molecule on Bovine Sperm Function and Embryo Production

João Campos Santos; Carla Cruz Marques; Maria Conceição Baptista; Jorge Pimenta; José Carlos Santos Teixeira; Liliana Montezinho; Fernando Cagide; et al, 2022. Animals. 2022. https://www.mdpi.com/2076-2615/12/7/804 . 10.3390/ani12070804 . Animals

Integrative Profiling of Amyotrophic Lateral Sclerosis Lymphoblasts Identifies Unique Metabolic and Mitochondrial Disease Fingerprints

Cunha-Oliveira, T.; Carvalho, Marcelo; Sardão, V.; Ferreiro, Elisabete; Mena, D.; Francisco B Pereira ; Borges, Fernanda; Oliveira, P.J.; Silva, Filomena, 2022. Research Square. 2022. https://www.researchsquare.com/article/rs-1196454/v1 . 10.21203/rs.3.rs-1196454/v1 . under revision Research Square

Evaluation of 6-Hydroxydopamine and Rotenone In Vitro Neurotoxicity on Differentiated SH-SY5Y Cells Using Applied Computational Statistics

Rui F. Simões; Paulo J. Oliveira; Teresa Cunha-Oliveira; Francisco B. Pereira, 2022. International Journal of Molecular Sciences. 3009 - 3009. 6. 23. 2022. https://doi.org/10.3390/ijms23063009 . 10.3390/ijms23063009 . International Journal of Molecular Sciences

Identification of a novel mutation in MEF2C gene in an atypical patient with Frontotemporal Lobar Degeneration

Grazina, Manuela, 2021. Neurological Sciences. 2021. in press Neurological Sciences

Refinement of a differentiation protocol using neuroblastoma SH-SY5Y cells for use in neurotoxicology research

Simões, Rui F.; Ferrão, Rafaela; Silva, Margarida R.; Pinho, Sonia L. C.; Ferreira, Lino; Oliveira, Paulo J.; # Cunha-Oliveira, T., 2021. Food and Chemical Toxicology. 2021. https://doi.org/10.1016/j.fct.2021.111967 . 10.1016/j.fct.2021.111967 . published Food and Chemical Toxicology

MPV17 mutations are associated with a quiescent energetic metabolic profile

Jacinto, Sandra; Guerreiro. Patrícia; Machado de Oliveira, Rita; Cunha-Oliveira, T.; Santos, Maria João; Grazina, Manuela; Rego, Ana Cristina; Outeiro, Tiago, 2021. Frontiers in Cellular Neuroscience. 2021. https://www.frontiersin.org/articles/10.3389/fncel.2021.641264/abstract . published Frontiers in Cellular Neuroscience

Mitochondrial and metabolic remodeling in human skin fibroblasts in response to glucose availability

Costa, C. F.; Pinho, S.A.; Pinho, S. L.; Miranda-Santos, I.; Bagshaw, O.; Stuart, J.; Oliveira, P.J.; # Cunha-Oliveira, T., 2021. BioRxiv. 2021. https://www.biorxiv.org/content/10.1101/2021.02.24.432508v1 . 10.1101/2021.02.24.432508 . published BioRxiv

MPV17 Mutations Are Associated With a Quiescent Energetic Metabolic Profile

Jacinto, Sandra; Guerreiro, Patrícia; de Oliveira, Rita Machado; Cunha-Oliveira, Teresa; Santos, Maria João; Grazina, Manuela; Rego, Ana Cristina; Outeiro, Tiago F., 2021. Frontiers in Cellular Neuroscience. 15. 2021. http://dx.doi.org/10.3389/fncel.2021.641264 . 10.3389/fncel.2021.641264 . published Frontiers in Cellular Neuroscience

Cytotoxicity and Mitochondrial Effects of Phenolic and Quinone-Based Mitochondria-Targeted and Untargeted Antioxidants on Human Neuronal and Hepatic Cell Lines: A Comparative Analysis

Fernandes, Carlos; Videira, Afonso J. C.; Veloso, Caroline D.; Benfeito, Sofia; Soares, Pedro; Martins, João D.; Gonçalves, Beatriz; et al, 2021. Biomolecules. 11. 11. 2021. http://dx.doi.org/10.3390/biom11111605 . 10.3390/biom11111605 . Biomolecules

The Alterations of Mitochondrial Function during NAFLD Progression—An Independent Effect of Mitochondrial ROS Production

Simões, Inês C. M.; Amorim, Ricardo; Teixeira, José; Karkucinska-Wieckowska, Agnieszka; Carvalho, Adriana; Pereira, Susana P.; Simões, Rui F.; et al, 2021. International Journal of Molecular Sciences. 13. 22. 2021. http://dx.doi.org/10.3390/ijms22136848 . 10.3390/ijms22136848 . International Journal of Molecular Sciences

A mitochondria-targeted caffeic acid derivative reverts cellular and mitochondrial defects in human skin fibroblasts from male sporadic Parkinson's disease patients

Deus, Cláudia M.; Pereira, Susana P.; Cunha-Oliveira, Teresa; Teixeira, José; Simões, Rui F.; Cagide, Fernando; Benfeito, Sofia; et al, 2021. Redox Biology. 45. 2021. http://dx.doi.org/10.1016/j.redox.2021.102037 . 10.1016/j.redox.2021.102037 . Redox Biology

Exploratory Data Analysis of Cell and Mitochondrial High-Fat, High-Sugar Toxicity on Human HepG2 Cells

Amorim, Ricardo; Simões, Inês C. M.; Veloso, Caroline; Carvalho, Adriana; Simões, Rui F.; Pereira, Francisco B.; Thiel, Theresa; et al, 2021. Nutrients. 5. 13. 2021. http://dx.doi.org/10.3390/nu13051723 . 10.3390/nu13051723 . Nutrients

Mitochondria-targeted phenolic antioxidants induce ROS-protective pathways in primary human skin fibroblasts

Teixeira, José; Basit, Farhan; Willems, Peter H.G.M.; Wagenaars, Jori A.; van de Westerlo, Els; Amorim, Ricardo; Cagide, Fernando; et al, 2021. Free Radical Biology and Medicine. 314 - 324. 163. 2021. http://dx.doi.org/10.1016/j.freeradbiomed.2020.12.023 . 10.1016/j.freeradbiomed.2020.12.023 . Free Radical Biology and Medicine

Sex-dependent vulnerability of fetal nonhuman primate cardiac mitochondria to moderate maternal nutrient reduction

Pereira, Susana P.; Tavares, Ludgero C.; Duarte, Ana I.; Baldeiras, Inês; Cunha-Oliveira, Teresa; Martins, João D.; Santos, Maria S.; et al, 2021. Clinical Science. 1103 - 1126. 9. 135. 2021. http://dx.doi.org/10.1042/cs20201339 . 10.1042/cs20201339 . published Clinical Science

The potential role of sestrin 2 in liver regeneration

Oliveira, Raúl P.; Machado, Ivo F.; Palmeira, Carlos M.; Rolo, Anabela P., 2021. Free Radical Biology and Medicine. 255 - 267. 163. 2021. http://dx.doi.org/10.1016/j.freeradbiomed.2020.12.027 . 10.1016/j.freeradbiomed.2020.12.027 . Free Radical Biology and Medicine

Sestrin2 and mitochondrial quality control: Potential impact in myogenic differentiation

Piochi, Luiz F.; Machado, Ivo F.; Palmeira, Carlos M.; Rolo, Anabela P., 2021. Ageing Research Reviews. 67. 2021. http://dx.doi.org/10.1016/j.arr.2021.101309 . 10.1016/j.arr.2021.101309 . Ageing Research Reviews

A mitochondria-targeted caffeic acid derivative reverts cellular and mitochondrial defects in human skin fibroblasts from male sporadic Parkinson's disease patients

Deus, Cláudia M.; Pereira, Susana P.; Cunha-Oliveira, Teresa; Teixeira, José; Simões, Rui F.; Cagide, Fernando; Benfeito, Sofia; et al, 2021. Redox Biology. 2021. http://dx.doi.org/10.1016/j.redox.2021.102037 . 10.1016/j.redox.2021.102037 . published Redox Biology

miR-378a-3p Participates in Metformin’s Mechanism of Action on C2C12 Cells under Hyperglycemia

Machado, Ivo F.; Teodoro, João S.; Castela, Ana C.; Palmeira, Carlos M.; Rolo, Anabela P., 2021. International Journal of Molecular Sciences. 2. 22. 2021. http://dx.doi.org/10.3390/ijms22020541 . 10.3390/ijms22020541 . International Journal of Molecular Sciences

Blueberry Counteracts Prediabetes in a Hypercaloric Diet-Induced Rat Model and Rescues Hepatic Mitochondrial Bioenergetics

Sara Nunes; Sofia D. Viana; Inês Preguiça; André Alves; R. Fernandes; Teodoro, J.S.; Patrícia Matos; et al, 2021. Nutrients. 2021. https://www.mdpi.com/2072-6643/13/12/4192 . 10.3390/nu13124192 . Nutrients

Quantitative analysis of neuronal mitochondrial movement reveals patterns resulting from neurotoxicity of rotenone and 6-hydroxydopamine

Rui F. Simões; Rute Pino; Maurício Moreira-Soares; Jaromira Kovarova; Jiri Neuzil; Rui Travasso; Paulo J. Oliveira; Teresa Cunha-Oliveira; Francisco B. Pereira, 2021. The FASEB Journal. 12. 35. 2021. https://doi.org/10.1096/fj.202100899R . 10.1096/fj.202100899R . The FASEB Journal

A mitochondria-targeted caffeic acid derivative reverts cellular and mitochondrial defects in human skin fibroblasts from male sporadic Parkinson's disease patients

Cláudia M. Deus; Susana P. Pereira; Teresa Cunha-Oliveira; José Teixeira; Rui F. Simões; Fernando Cagide; Sofia Benfeito; et al, 2021. Redox Biology. 102037 - 102037. 45. 2021. https://doi.org/10.1016/j.redox.2021.102037 . 10.1016/j.redox.2021.102037 . Redox Biology

Metabolic Disease Programming: From Mitochondria to Epigenetics, Glucocorticoid Signalling and Beyond

Luís F. Grilo; Carolina Tocantins; Mariana S. Diniz; Rodrigo Mello Gomes; Paulo J. Oliveira; Paulo Matafome; Susana P. Pereira, 2021. European Journal of Clinical Investigation. 2021. https://doi.org/10.1111/eci.13625 . 10.1111/eci.13625 . European Journal of Clinical Investigation

Chenodeoxycholic Acid Has Non-Thermogenic, Mitodynamic Anti-Obesity Effects in an In Vitro CRISPR/Cas9 Model of Bile Acid Receptor TGR5 Knockdown

Teodoro, João S.; Machado, Ivo F.; Castela, Ana C.; Amorim, João A.; Jarak, Ivana; Carvalho, Rui A.; Palmeira, Carlos M.; Rolo, Anabela P., 2021. International Journal of Molecular Sciences. 21. 22. 2021. http://dx.doi.org/10.3390/ijms222111738 . 10.3390/ijms222111738 . International Journal of Molecular Sciences

Quantitative analysis of neuronal mitochondrial movement reveals patterns resulting from neurotoxicity of rotenone and 6-hydroxydopamine

Rui F. Simões; Rute Pino; Maurício Moreira-Soares; Jaromira Kovarova; Jiri Neuzil; Rui Travasso; Paulo J. Oliveira; Teresa Cunha-Oliveira; Francisco B. Pereira, 2021. The FASEB Journal. 12. 35. 2021. https://doi.org/10.1096/fj.202100899R . 10.1096/fj.202100899R . The FASEB Journal

Fine-Tuning the Biological Profile of Multitarget Mitochondriotropic Antioxidants for Neurodegenerative Diseases

Daniel Chavarria; Ophelie DA SILVA; Sofia Benfeito; Sandra Barreiro; Jorge Garrido; Cagide-Fagín; Pedro Soares; et al, 2021. Antioxidants. 2021. https://www.mdpi.com/2076-3921/10/2/329 . 10.3390/antiox10020329 . Antioxidants

Refinement of a differentiation protocol using neuroblastoma SH-SY5Y cells for use in neurotoxicology research

Rui F. Simões; Rafaela Ferrão; Margarida R. Silva; Sonia L.C. Pinho; Lino Ferreira; Paulo J. Oliveira; Teresa Cunha-Oliveira, 2021. Food and Chemical Toxicology. 111967 - 111967. 149. 2021. https://doi.org/10.1016/j.fct.2021.111967 . 10.1016/j.fct.2021.111967 . Food and Chemical Toxicology

Afrostyrax lepidophyllus Mildbr. and Monodora myristica (Gaertn.) Dunal Extracts Decrease Doxorubicin Cytotoxicity on H9c2 Cardiomyoblasts

Bruno M. Moukette; José P. Castelão-Baptista; Luciana Ferreira; Ana M. Silva; Rui F. Simões; Célia Cabral; Constant A. Pieme; et al, 2021. Evidence-Based Complementary and Alternative Medicine. 2021. https://doi.org/10.1155/2021/8858165 . 10.1155/2021/8858165 . Evidence-Based Complementary and Alternative Medicine

H9c2(2-1)-based sulforhodamine B assay as a possible alternative in vitro platform to investigate effluent and metals toxicity on fish

Elsa T. Rodrigues; Miguel A. Pardal; Eduarda Pereira; Joana F. Monteiro; Ana C. Certal; Paulo J. Oliveira, 2021. Chemosphere. 2021. https://doi.org/10.1016/j.chemosphere.2021.130009 . 10.1016/j.chemosphere.2021.130009 . Chemosphere

Cytotoxicity and Mitochondrial Effects of Phenolic and Quinone-Based Mitochondria-Targeted and Untargeted Antioxidants on Human Neuronal and Hepatic Cell Lines: A Comparative Analysis

Carlos Fernandes; Afonso J. C. Videira; Caroline D. Veloso; Sofia Benfeito; Pedro Soares; João D. Martins; Beatriz Gonçalves; et al, 2021. Biomolecules. 1605 - 1605. 11. 11. 2021. https://doi.org/10.3390/biom11111605 . 10.3390/biom11111605 . Biomolecules

Glutaminolysis is a metabolic route essential for survival and growth of prostate cancer cells and a target of 5a-dihydrotestosterone regulation

Henrique J. Cardoso; Marília I. Figueira; Cátia V. Vaz; Tiago M. A. Carvalho; Luís A. Brás; Patrícia A. Madureira; Paulo J. Oliveira; Vilma A. Sardão; Sílvia Socorro, 2021. Cellular Oncology. 2021. https://doi.org/10.1007/s13402-020-00575-9 . 10.1007/s13402-020-00575-9 . Cellular Oncology

Urine-Derived Stem Cells: Applications in Regenerative and Predictive Medicine

Guida Bento; Aygul K. Shafigullina; Albert A. Rizvanov; Vilma A. Sardão; Maria Paula Macedo; Paulo J. Oliveira, 2020. Cells. 573 - 573. 3. 9. 2020. https://doi.org/10.3390/cells9030573 . 10.3390/cells9030573 . Cells

Drp1-mediated mitochondrial fission regulates calcium and F-actin dynamics during wound healing

Susana Ponte; Lara Carvalho; Maria Gagliardi; Isabel Campos; Paulo J. Oliveira; António Jacinto, 2020. Biology Open. 2020. https://doi.org/10.1242/bio.048629 . 10.1242/bio.048629 . Biology Open

Blueberry Consumption Challenges Hepatic Mitochondrial Bioenergetics and Elicits Transcriptomics Reprogramming in Healthy Wistar Rats

Nunes, Sara; Viana, Sofia D.; Preguiça, Inês; Alves, André; Fernandes, Rosa; Teodoro, João S.; Figueirinha, Artur; et al, 2020. Pharmaceutics. 11. 12. 2020. http://dx.doi.org/10.3390/pharmaceutics12111094 . 10.3390/pharmaceutics12111094 . Pharmaceutics

The Soluble Adenylyl Cyclase Inhibitor LRE1 Prevents Hepatic Ischemia/Reperfusion Damage Through Improvement of Mitochondrial Function

Teodoro, João S.; Amorim, João A.; Machado, Ivo F.; Castela, Ana C.; Steegborn, Clemens; Sinclair, David A.; Rolo, Anabela P.; Palmeira, Carlos M., 2020. International Journal of Molecular Sciences. 14. 21. 2020. http://dx.doi.org/10.3390/ijms21144896 . 10.3390/ijms21144896 . International Journal of Molecular Sciences

Exploration of the cellular effects of the high-dose, long-term exposure to coffee roasting product furan and its by-product cis-2-butene-1,4-dial on human and rat hepatocytes

João S. Teodoro; Rui Silva; António Aguiar; Abílio J. F. N. Sobral; Anabela P. Rolo; Carlos M. Palmeira, 2020. Toxicology Mechanisms and Methods. 536 - 545. 7. 30. 2020. https://doi.org/10.1080/15376516.2020.1780361 . 10.1080/15376516.2020.1780361 . Toxicology Mechanisms and Methods

Dihydroorotate dehydrogenase inhibitors in SARS-CoV-2 infection

Ana R. Coelho; Paulo J. Oliveira, 2020. European Journal of Clinical Investigation. 2020. https://doi.org/10.1111/eci.13366 . 10.1111/eci.13366 . European Journal of Clinical Investigation

Mitochondrial remodeling in human skin fibroblasts from sporadic male Parkinson's disease patients uncovers metabolic and mitochondrial bioenergetic defects

Deus, Cláudia M.; Pereira, Susana P.; Cunha-Oliveira, Teresa; Pereira, Francisco B.; Raimundo, Nuno; Oliveira, Paulo J., 2020. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 3. 1866. 2020. http://dx.doi.org/10.1016/j.bbadis.2019.165615 . 10.1016/j.bbadis.2019.165615 . published Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

Maternal obesity in sheep impairs foetal hepatic mitochondrial respiratory chain capacity

Serafim, Teresa L.; * Cunha-Oliveira, Teresa; Deus, Claudia M.; Sardão, Vilma A.; Cardoso, Ines M.; Yang, Shanshan; Odhiambo, John F.; et al, 2020. European Journal of Clinical Investigation. 2. 51. 2020. http://dx.doi.org/10.1111/eci.13375 . 10.1111/eci.13375 . published European Journal of Clinical Investigation

Oxidative Stress in Amyotrophic Lateral Sclerosis: Pathophysiology and Opportunities for Pharmacological Intervention

Teresa Cunha-Oliveira; Liliana Montezinho; Catarina Mendes; Omidreza Firuzi; Luciano Saso; Paulo J. Oliveira; Filomena S. G. Silva; Jos L. Quiles, 2020. Oxidative Medicine and Cellular Longevity. 2020. https://doi.org/10.1155/2020/5021694 . 10.1155/2020/5021694 . Oxidative Medicine and Cellular Longevity

Mitochondrial Determinants of Doxorubicin-Induced Cardiomyopathy

Kendall B. Wallace; Vilma A. Sardão; Paulo J. Oliveira, 2020. Circulation Research. 926 - 941. 7. 126. 2020. https://doi.org/10.1161/CIRCRESAHA.119.314681 . 10.1161/CIRCRESAHA.119.314681 . Circulation Research

Doxorubicin persistently rewires cardiac circadian homeostasis in mice

Luciana L. Ferreira; Marlene Cervantes; Hugo J. C. Froufe; Conceição Egas; Teresa Cunha-Oliveira; Paolo Sassone-Corsi; Paulo J. Oliveira, 2020. Archives of Toxicology. 257 - 271. 1. 94. 2020. https://doi.org/10.1007/s00204-019-02626-z . 10.1007/s00204-019-02626-z . Archives of Toxicology

The yin and yang faces of the mitochondrial deacetylase sirtuin 3 in age-related disorders

Gomes, P.; Viana, S.D.; Nunes, S.; Rolo, A.P.; Palmeira, C.M.; Reis, F., 2020. Ageing Research Reviews. 57. 2020. http://www.scopus.com/inward/record.url?eid=2-s2.0-85076952156&partnerID=MN8TOARS . 10.1016/j.arr.2019.100983 . Ageing Research Reviews

Publicly stressing the role of mitochondria in NAFLD with(in) a sports event

Mireia Alemany-Pagès; Rui Tavares; Sara Varela Amaral; Ana Teresa Barros-Viegas; Paulo J. Oliveira; João Ramalho-Santos; Anabela Marisa Azul, 2020. European Journal of Clinical Investigation. 2020. https://doi.org/10.1111/eci.13234 . 10.1111/eci.13234 . European Journal of Clinical Investigation

Western Diet Causes Obesity-Induced Nonalcoholic Fatty Liver Disease Development by Differentially Compromising the Autophagic Response

Ines C. M. Simoes; Agnieszka Karkucinska-Wieckowska; Justyna Janikiewicz; Sylwia Szymanska; Maciej Pronicki; Pawel Dobrzyn; Michal Dabrowski; et al, 2020. Antioxidants. 995 - 995. 10. 9. 2020. https://doi.org/10.3390/antiox9100995 . 10.3390/antiox9100995 . Antioxidants

Stimulation of cell invasion by the Golgi Ion Channel GAAP/TMBIM4 via an H<inf>2</inf>O<inf>2</inf>-Dependent Mechanism

Almeida, N.; Carrara, G.; Palmeira, C.M.; Fernandes, A.S.; Parsons, M.; Smith, G.L.; Saraiva, N., 2020. Redox Biology. 28. 2020. http://www.scopus.com/inward/record.url?eid=2-s2.0-85074222003&partnerID=MN8TOARS . 10.1016/j.redox.2019.101361 . Redox Biology

Altered mitochondrial metabolism in the insulin-resistant heart

Makrecka-Kuka, M.; Liepinsh, E.; Murray, A.J.; Lemieux, H.; Dambrova, M.; Tepp, K.; Puurand, M.; et al, 2020. Acta Physiologica. 3. 228. 2020. http://www.scopus.com/inward/record.url?eid=2-s2.0-85077842678&partnerID=MN8TOARS . 10.1111/apha.13430 . Acta Physiologica

Oxidative Stress in Amyotrophic Lateral Sclerosis: Pathophysiology and Opportunities for Pharmacological Intervention

Cunha-Oliveira, Teresa; Montezinho, Liliana; Mendes, Catarina; Firuzi, Omidreza; Saso, Luciano; Oliveira, Paulo J.; Silva, Filomena S. G., 2020. Oxidative Medicine and Cellular Longevity. 1 - 29. 2020. 2020. http://dx.doi.org/10.1155/2020/5021694 . 10.1155/2020/5021694 . published Oxidative Medicine and Cellular Longevity

MYOC Gene Sequencing Analysis in Primary Open-Angle Glaucoma Patients from the Centre Region of Portugal

Silva, Filipe; Ferreira, Filipa; Faria, Pedro; Sobral, Isa; Rodrigues, Mariana; Pratas, João; Silva, João Filipe; et al, 2020. Acta Médica Portuguesa. 13. 34. 2020. http://dx.doi.org/10.20344/amp.14922 . 10.20344/amp.14922 . published Acta Médica Portuguesa

Insights into the Discovery of Novel Neuroprotective Agents: A Comparative Study between Sulfanylcinnamic Acid Derivatives and Related Phenolic Analogues

Daniel Chavarria; Carlos Fernandes; Brandon Aguiar; Tiago Silva; Jorge Garrido; Fernando Remiao; Paulo J. Oliveira; Eugenio Uriarte; Borges Fernanda, 2019. Molecules. 2019. https://www.mdpi.com/1420-3049/24/23/4405 . 10.3390/molecules24234405 . Molecules

Bioisosteric OH- to SH-replacement changes the antioxidant profile of ferulic acid

Daniel Chavarria; Carlos Fernandes; Tiago Silva; Jorge Garrido; Fernando Remião; Paulo J. Oliveira; Fernanda Borges, 2019. Organic & Biomolecular Chemistry. 2019. https://doi.org/10.1039/C9OB01875A . 10.1039/C9OB01875A . Organic & Biomolecular Chemistry

Single nanomolar doxorubicin exposure triggers compensatory mitochondrial responses in H9c2 cardiomyoblasts

Luciana L. Ferreira; Teresa Cunha-Oliveira; Caroline D. Veloso; Cláudio F. Costa; Kendall B. Wallace; Paulo J. Oliveira, 2019. Food and Chemical Toxicology. 450 - 461. 124. 2019. https://doi.org/10.1016/j.fct.2018.12.017 . 10.1016/j.fct.2018.12.017 . Food and Chemical Toxicology

Genomic Ancestry, CYP2D6, CYP2C9, and CYP2C19 Among Latin Americans

Rodrigues-Soares, Fernanda; Peñas-Lledó, Eva M.; Tarazona-Santos, Eduardo; Sosa-Macías, Martha; Terán, Enrique; López-López, Marisol; Rodeiro, Idania; et al, 2019. Clinical Pharmacology & Therapeutics. 257 - 268. 1. 107. 2019. http://dx.doi.org/10.1002/cpt.1598 . 10.1002/cpt.1598 . published Clinical Pharmacology & Therapeutics

Antioxidant Versus Pro-Apoptotic Effects of Mushroom-Enriched Diets on Mitochondria in Liver Disease

Adriana Fontes; Mireia Alemany-Pagès; Paulo J. Oliveira; João Ramalho-Santos; Hans Zischka; Anabela Marisa Azul, 2019. International Journal of Molecular Sciences. 3987 - 3987. 16. 20. 2019. https://doi.org/10.3390/ijms20163987 . 10.3390/ijms20163987 . International Journal of Molecular Sciences

A Mitochondrial Approach to Cardiovascular Risk and Disease

Caroline D. Veloso; Getachew D. Belew; Luciana L. Ferreira; Luís Filipe Fragoso Grilo; John G. Jones; Piero Portincasa; Vilma A. Sardão; Paulo J. Oliveira, 2019. Current Protein & Peptide Science. 2019. https://doi.org/10.2174/1389203720666190830163735 . 10.2174/1389203720666190830163735 . Current Protein & Peptide Science

Therapeutic options targeting oxidative stress, mitochondrial dysfunction and inflammation to hinder the progression of vascular complications of diabetes

Teodoro, J.S.; Nunes, S.; Rolo, A.P.; Reis, F.; Palmeira, C.M., 2019. Frontiers in Physiology. JAN. 10. 2019. http://www.scopus.com/inward/record.url?eid=2-s2.0-85065463466&partnerID=MN8TOARS . 10.3389/fphys.2018.01857 . Frontiers in Physiology

Correspondence

Alexandrino, H.; Palmeira, C., 2019. British Journal of Surgery. 152 - 152. 1. 106. 2019. http://www.scopus.com/inward/record.url?eid=2-s2.0-85058912518&partnerID=MN8TOARS . 10.1002/bjs.11055 . British Journal of Surgery

Mild hypothermia during the reperfusion phase protects mitochondrial bioenergetics against ischemia-reperfusion injury in an animal model of ex-vivo liver transplantation—An experimental study

Martins, R.M.; Teodoro, J.S.; Furtado, E.; Oliveira, R.C.; Tralhão, J.G.; Rolo, A.P.; Palmeira, C.M., 2019. International Journal of Medical Sciences. 1304 - 1312. 9. 16. 2019. http://www.scopus.com/inward/record.url?eid=2-s2.0-85072941379&partnerID=MN8TOARS . 10.7150/ijms.34617 . International Journal of Medical Sciences

Evaluation of bioenergetic and mitochondrial function in liver transplantation

Martins, R.M.; Teodoro, J.S.; Furtado, E.; Rolo, A.P.; Palmeira, C.M.; Tralhão, J.G., 2019. Clinical and Molecular Hepatology. 190 - 198. 2. 25. 2019. http://www.scopus.com/inward/record.url?eid=2-s2.0-85068517981&partnerID=MN8TOARS . 10.3350/cmh.2018.0087 . Clinical and Molecular Hepatology

Mitohormesis and metabolic health: The interplay between ROS, cAMP and sirtuins

Palmeira, C.M.; Teodoro, J.S.; Amorim, J.A.; Steegborn, C.; Sinclair, D.A.; Rolo, A.P., 2019. Free Radical Biology and Medicine. 483 - 491. 141. 2019. http://www.scopus.com/inward/record.url?eid=2-s2.0-85069629808&partnerID=MN8TOARS . 10.1016/j.freeradbiomed.2019.07.017 . Free Radical Biology and Medicine

Enhanced ATP release and CD73-mediated adenosine formation sustain adenosine A<inf>2A</inf> receptor over-activation in a rat model of Parkinson's disease

Carmo, M.; Gonçalves, F.Q.; Canas, P.M.; Oses, J.-P.; Fernandes, F.D.; Duarte, F.V.; Palmeira, C.M.; et al, 2019. British Journal of Pharmacology. 3666 - 3680. 18. 176. 2019. http://www.scopus.com/inward/record.url?eid=2-s2.0-85070072977&partnerID=MN8TOARS . 10.1111/bph.14771 . British Journal of Pharmacology

Targeting mitochondria to oppose the progression of nonalcoholic fatty liver disease

Ignazio Grattagliano; Liliana P. Montezinho; Paulo J. Oliveira; Gema Frühbeck; Javier Gómez-Ambrosi; Fabrizio Montecucco; Federico Carbone; et al, 2019. Biochemical Pharmacology. 34 - 45. 160. 2019. https://doi.org/10.1016/j.bcp.2018.11.020 . 10.1016/j.bcp.2018.11.020 . Biochemical Pharmacology

Evaluation of bioenergetic and mitochondrial function in liver transplantation

Martins, Rui Miguel; Teodoro, João Soeiro; Furtado, Emanuel; Rolo, Anabela Pinto; Palmeira, Carlos Marques; Tralhão, José Guilherme, 2019. Clinical and Molecular Hepatology. 190 - 198. 2. 25. 2019. http://dx.doi.org/10.3350/cmh.2018.0087 . 10.3350/cmh.2018.0087 . Clinical and Molecular Hepatology

miR-378a: a new emerging microRNA in metabolism

Machado, I.F.; Teodoro, J.S.; Palmeira, C.M.; Rolo, A.P., 2019. Cellular and Molecular Life Sciences. 2019. http://www.scopus.com/inward/record.url?eid=2-s2.0-85075434955&partnerID=MN8TOARS . 10.1007/s00018-019-03375-z . Cellular and Molecular Life Sciences

Cell-based assays seem not to accurately predict fish short-term toxicity of pesticides

Elsa T. Rodrigues; Ana T. Varela; Miguel A. Pardal; Paulo J. Oliveira, 2019. Environmental Pollution. 476 - 482. 252. 2019. https://doi.org/10.1016/j.envpol.2019.05.033 . 10.1016/j.envpol.2019.05.033 . Environmental Pollution

Transfer of glucose hydrogens via acetyl-CoA, malonyl-CoA, and NADPH to fatty acids during de novo lipogenesis

Belew, Getachew Debas; Silva, Joao; Rito, Joao; Tavares, Ludgero; Viegas, Ivan; Teixeira, Jose; Oliveira, Paulo J.; Macedo, Maria Paula; Jones, John G., 2019. Journal of Lipid Research. 2050 - 2056. 12. 60. 2019. http://dx.doi.org/10.1194/jlr.ra119000354 . 10.1194/jlr.ra119000354 . published Journal of Lipid Research

Impact of Carcinogenic Chromium on the Cellular Response to Proteotoxic Stress

Ferreira, Leonardo M. R.; Cunha-Oliveira, Teresa; Sobral, Margarida C.; Abreu, Patrícia L.; Alpoim, Maria Carmen; Urbano, Ana M., 2019. International Journal of Molecular Sciences. 19. 20. 2019. http://dx.doi.org/10.3390/ijms20194901 . 10.3390/ijms20194901 . published International Journal of Molecular Sciences

Doxorubicin persistently rewires cardiac circadian homeostasis in mice

Ferreira, Luciana L.; Cervantes, Marlene; Froufe, Hugo J. C.; Egas, Conceição; Cunha-Oliveira, Teresa; Sassone-Corsi, Paolo; Oliveira, Paulo J., 2019. Archives of Toxicology. 2019. http://dx.doi.org/10.1007/s00204-019-02626-z . 10.1007/s00204-019-02626-z . published Archives of Toxicology

Intracellular and Intercellular Mitochondrial Dynamics in Parkinson's Disease

Valdinocci, Dario; Simões, Rui F.; Kovarova, Jaromira; Cunha-Oliveira, Teresa; Neuzil, Jiri; Pountney, Dean L., 2019. Frontiers in Neuroscience. 13. 2019. http://dx.doi.org/10.3389/fnins.2019.00930 . 10.3389/fnins.2019.00930 . Frontiers in Neuroscience

Single nanomolar doxorubicin exposure triggers compensatory mitochondrial responses in H9c2 cardiomyoblasts

Ferreira, Luciana L.; Cunha-Oliveira, Teresa; Veloso, Caroline D.; Costa, Cláudio F.; Wallace, Kendall B.; Oliveira, Paulo J., 2019. Food and Chemical Toxicology. 450 - 461. 124. 2019. http://dx.doi.org/10.1016/j.fct.2018.12.017 . 10.1016/j.fct.2018.12.017 . published Food and Chemical Toxicology

Reactivation of Dihydroorotate Dehydrogenase-Driven Pyrimidine Biosynthesis Restores Tumor Growth of Respiration-Deficient Cancer Cells

Bajzikova, Martina; Kovarova, Jaromira; Coelho, Ana R.; Boukalova, Stepana; Oh, Sehyun; Rohlenova, Katerina; Svec, David; et al, 2019. Cell Metabolism. 399 - 416.e10. 2. 29. 2019. http://dx.doi.org/10.1016/j.cmet.2018.10.014 . 10.1016/j.cmet.2018.10.014 . published Cell Metabolism

Fine-tuning the neuroprotective and blood-brain barrier permeability profile of multi-target agents designed to prevent progressive mitochondrial dysfunction

Benfeito, S.; Oliveira, C.; Fernandes, C.; Cagide, F.; Teixeira, J.; Amorim, R.; Garrido, J.; et al, 2019. European Journal of Medicinal Chemistry. 525 - 545. 167. 2019. http://dx.doi.org/10.1016/j.ejmech.2019.01.055 . 10.1016/j.ejmech.2019.01.055 . published European Journal of Medicinal Chemistry

Benzoic acid-derived nitrones: A new class of potential acetylcholinesterase inhibitors and neuroprotective agents

Oliveira, Catarina; Bagetta, Donatella; Cagide, Fernando; Teixeira, José; Amorim, Ricardo; Silva, Tiago; Garrido, Jorge; et al, 2019. European Journal of Medicinal Chemistry. 116 - 129. 174. 2019. http://dx.doi.org/10.1016/j.ejmech.2019.04.026 . 10.1016/j.ejmech.2019.04.026 . published European Journal of Medicinal Chemistry

Desrisking the Cytotoxicity of a Mitochondriotropic Antioxidant Based on Caffeic Acid by a PEGylated Strategy

Carlos Fernandes; Sofia Benfeito; Ricardo Amorim; José Teixeira; Paulo J. Oliveira; Fernando Remião; Fernanda Borges, 2018. Bioconjugate Chemistry. 2018. https://doi.org/10.1021/acs.bioconjchem.8b00383 . 10.1021/acs.bioconjchem.8b00383 . published Bioconjugate Chemistry

Mitochondria: Targeting mitochondrial reactive oxygen species with mitochondriotropic polyphenolic-based antioxidants

Teixeira, José; Deus, Cláudia M.; Borges, Fernanda; Oliveira, Paulo J., 2018. The International Journal of Biochemistry & Cell Biology. 98 - 103. 97. 2018. http://dx.doi.org/10.1016/j.biocel.2018.02.007 . 10.1016/j.biocel.2018.02.007 . published The International Journal of Biochemistry & Cell Biology

Hydroxybenzoic Acid Derivatives as Dual-Target Ligands: Mitochondriotropic Antioxidants and Cholinesterase Inhibitors

Oliveira, Catarina; Cagide, Fernando; Teixeira, José; Amorim, Ricardo; Sequeira, Lisa; Mesiti, Francesco; Silva, Tiago; et al, 2018. Frontiers in Chemistry. 6. 2018. http://dx.doi.org/10.3389/fchem.2018.00126 . 10.3389/fchem.2018.00126 . published Frontiers in Chemistry

Indirubin and NAD<sup>+</sup> prevent mitochondrial ischaemia/reperfusion damage in fatty livers

Teodoro, J.S.; Varela, A.T.; Duarte, F.V.; Gomes, A.P.; Palmeira, C.M.; Rolo, A.P., 2018. European Journal of Clinical Investigation. 6. 48. 2018. http://www.scopus.com/inward/record.url?eid=2-s2.0-85045238716&partnerID=MN8TOARS . 10.1111/eci.12932 . European Journal of Clinical Investigation

Hexavalent chromium, a lung carcinogen, confers resistance to thermal stress and interferes with heat shock protein expression in human bronchial epithelial cells

Abreu, Patrícia L.; Cunha-Oliveira, Teresa; Ferreira, Leonardo M. R.; Urbano, Ana M., 2018. BioMetals. 477 - 487. 4. 31. 2018. http://dx.doi.org/10.1007/s10534-018-0093-7 . 10.1007/s10534-018-0093-7 . published BioMetals

Disclosing the functional changes of two genetic alterations in a patient with Chronic Progressive External Ophthalmoplegia: Report of the novel mtDNA m.7486G>A variant

Bacalhau, Mafalda; Simões, Marta; Rocha, Mariana C.; Hardy, Steven A.; Vincent, Amy E.; Durães, João; Macário, Maria C.; et al, 2018. Neuromuscular Disorders. 350 - 360. 4. 28. 2018. http://dx.doi.org/10.1016/j.nmd.2017.11.006 . 10.1016/j.nmd.2017.11.006 . Neuromuscular Disorders

CYP2D6 Pharmacogenetics Testing and Post–Cesarean Section Pain Scores—a Preliminary Study

Ribeiro, Carolina; Quinta, Rosa; Raposo, Ana; Valentim, Ana; Albuquerque, José; Grazina, Manuela, 2018. Pain Medicine. 359 - 368. 2. 20. 2018. http://dx.doi.org/10.1093/pm/pny033 . 10.1093/pm/pny033 . Pain Medicine

Interethnic Variability in CYP2D6, CYP2C9, and CYP2C19 Genes and Predicted Drug Metabolism Phenotypes Among 6060 Ibero- and Native Americans: RIBEF-CEIBA Consortium Report on Population Pharmacogenomics

Naranjo, María-Eugenia G.; Rodrigues-Soares, Fernanda; Peñas-Lledó, Eva M.; Tarazona-Santos, Eduardo; Fariñas, Humberto; Rodeiro, Idania; Terán, Enrique; et al, 2018. OMICS: A Journal of Integrative Biology. 575 - 588. 9. 22. 2018. http://dx.doi.org/10.1089/omi.2018.0114 . 10.1089/omi.2018.0114 . OMICS: A Journal of Integrative Biology

Metabolic and Phenotypic Characterization of Human Skin Fibroblasts After Forcing Oxidative Capacity

Pereira, Susana P; Deus, Cláudia M; Serafim, Teresa L; Cunha-Oliveira, Teresa; Oliveira, Paulo J, 2018. Toxicological Sciences. 191 - 204. 1. 164. 2018. http://dx.doi.org/10.1093/toxsci/kfy068 . 10.1093/toxsci/kfy068 . published Toxicological Sciences

Discovery of a new mitochondria permeability transition pore (mPTP) inhibitor based on gallic acid

José Teixeira; Catarina Oliveira; Fernando Cagide; Ricardo Amorim; Jorge Garrido; Fernanda Borges; Paulo J. Oliveira, 2018. Journal of Enzyme Inhibition and Medicinal Chemistry. 567 - 576. 1. 33. 2018. https://doi.org/10.1080/14756366.2018.1442831 . 10.1080/14756366.2018.1442831 . Journal of Enzyme Inhibition and Medicinal Chemistry

Sources of hepatic glycogen synthesis in mice fed with glucose or fructose as the sole dietary carbohydrate

Jarak, Ivana; Barosa, Cristina; Martins, Fatima O.; Silva, Joao C. P.; Santos, Cristiano; Belew, Getachew Debas; Rito, Joao; et al, 2018. Magnetic Resonance in Medicine. 639 - 644. 1. 81. 2018. http://dx.doi.org/10.1002/mrm.27378 . 10.1002/mrm.27378 . published Magnetic Resonance in Medicine

Multi-target-directed ligands for Alzheimer's disease: Discovery of chromone-based monoamine oxidase/cholinesterase inhibitors

Reis, Joana; Cagide, Fernando; Valencia, Martín Estrada; Teixeira, José; Bagetta, Donatella; Pérez, Concepción; Uriarte, Eugenio; et al, 2018. European Journal of Medicinal Chemistry. 781 - 800. 158. 2018. http://dx.doi.org/10.1016/j.ejmech.2018.07.056 . 10.1016/j.ejmech.2018.07.056 . published European Journal of Medicinal Chemistry

Electrochemical Behavior of a Mitochondria-Targeted Antioxidant at an Interface between Two Immiscible Electrolyte Solutions: An Alternative Approach to Study Lipophilicity

Ribeiro, José A.; Benfeito, Sofia; Cagide, Fernando; Teixeira, José; Oliveira, Paulo J.; Borges, Fernanda; Silva, António F.; Pereira, Carlos M., 2018. Analytical Chemistry. 7989 - 7996. 13. 90. 2018. http://dx.doi.org/10.1021/acs.analchem.8b00787 . 10.1021/acs.analchem.8b00787 . published Analytical Chemistry

Research update for articles published in EJCI in 2016

Adlbrecht, C.; Blanco-Verea, A.; Bouzas-Mosquera, M.C.; Brion, M.; Burtscher, M.; Carbone, F.; Chang, T.-T.; et al, 2018. European Journal of Clinical Investigation. 10. 48. 2018. http://www.scopus.com/inward/record.url?eid=2-s2.0-85053529293&partnerID=MN8TOARS . 10.1111/eci.13016 . European Journal of Clinical Investigation

Mitochondrial damage and apoptosis: Key features in BDE-153-induced hepatotoxicity

Pereira, L.C.; Cabral Miranda, L.F.; Franco-Bernardes, M.F.; Tasso, M.J.; Duarte, F.V.; Inácio Varela, A.T.; Rolo, A.P.; Marques Palmeira, C.M.; Dorta, D.J., 2018. Chemico-Biological Interactions. 192 - 201. 291. 2018. http://www.scopus.com/inward/record.url?eid=2-s2.0-85049064624&partnerID=MN8TOARS . 10.1016/j.cbi.2018.06.021 . Chemico-Biological Interactions

Recent insights into mitochondrial targeting strategies in liver transplantation

Martins, R.M.; Teodoro, J.S.; Furtado, E.; Rolo, A.P.; Palmeira, C.M.; Tralhão, J.G., 2018. International Journal of Medical Sciences. 248 - 256. 3. 15. 2018. http://www.scopus.com/inward/record.url?eid=2-s2.0-85045188539&partnerID=MN8TOARS . 10.7150/ijms.22891 . International Journal of Medical Sciences

Cytoprotective mechanisms in fatty liver preservation against cold ischemia injury: A comparison between IGL-1 and HTK

Panisello-Roselló, A.; Verde, E.; Lopez, A.; Flores, M.; Folch-Puy, E.; Rolo, A.; Palmeira, C.; et al, 2018. International Journal of Molecular Sciences. 2. 19. 2018. http://www.scopus.com/inward/record.url?eid=2-s2.0-85041019515&partnerID=MN8TOARS . 10.3390/ijms19020348 . International Journal of Molecular Sciences

Corrigendum to “European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS)” (Redox Biol. (2017) 13 (94–162)(S2213231717303373)(10.1016/j.redox.2017.05.007))

Egea, J.; Fabregat, I.; Frapart, Y.M.; Ghezzi, P.; Görlach, A.; Kietzmann, T.; Kubaichuk, K.; et al, 2018. Redox Biology. 694 - 696. 14. 2018. http://www.scopus.com/inward/record.url?eid=2-s2.0-85032289195&partnerID=MN8TOARS . 10.1016/j.redox.2017.10.001 . Redox Biology

Addition of berberine to preservation solution in an animal model of ex vivo liver transplant preserves mitochondrial function and bioenergetics from the damage induced by ischemia/reperfusion

Martins, R.M.; Rolo, A.P.; Teodoro, J.S.; Furtado, E.; Oliveira, R.C.; Tralhão, J.G.; Palmeira, C.M., 2018. International Journal of Molecular Sciences. 1. 19. 2018. http://www.scopus.com/inward/record.url?eid=2-s2.0-85040938454&partnerID=MN8TOARS . 10.3390/ijms19010284 . International Journal of Molecular Sciences

Aldehyde dehydrogenase 2 (ALDH2) in rat fatty liver cold ischemia injury

Panisello-Roselló, A.; Alva, N.; Flores, M.; Lopez, A.; Benítez, C.C.; Folch-Puy, E.; Rolo, A.; et al, 2018. International Journal of Molecular Sciences. 9. 19. 2018. http://www.scopus.com/inward/record.url?eid=2-s2.0-85052507134&partnerID=MN8TOARS . 10.3390/ijms19092479 . International Journal of Molecular Sciences

Doxorubicin triggers bioenergetic failure and p53 activation in mouse stem cell-derived cardiomyocytes

# Teresa Cunha-Oliveira; Luciana L. Ferreira; Ana Raquel Coelho; Cláudia M. Deus; Paulo J. Oliveira, 2018. Toxicology and Applied Pharmacology. 1 - 13. 348. 2018. https://doi.org/10.1016/j.taap.2018.04.009 . 10.1016/j.taap.2018.04.009 . published Toxicology and Applied Pharmacology

TRAP1 regulates autophagy in lung cancer cells.

Barbosa IA; Vega-Naredo I; Loureiro R; Branco AF; Garcia R; Scott PM; Oliveira PJ, 2018. European journal of clinical investigation. 2018. http://europepmc.org/abstract/med/29383696 . 10.1111/eci.12900 . European journal of clinical investigation

Role of aldehyde dehydrogenase 2 in ischemia reperfusion injury: An update

Panisello-Roselló, A.; Lopez, A.; Folch-Puy, E.; Carbonell, T.; Rolo, A.; Palmeira, C.; Adam, R.; Net, M.; Roselló-Catafau, J., 2018. World Journal of Gastroenterology. 2984 - 2994. 27. 24. 2018. http://www.scopus.com/inward/record.url?eid=2-s2.0-85050972436&partnerID=MN8TOARS . 10.3748/wjg.v24.i27.2984 . World Journal of Gastroenterology

The beneficial role of exercise in mitigating doxorubicin-induced Mitochondrionopathy.

Marques-Aleixo I; Santos-Alves E; Oliveira PJ; Moreira PI; Magalhães J; Ascensão A, 2018. Biochimica et biophysica acta. Reviews on cancer. 2018. http://europepmc.org/abstract/med/29408395 . 10.1016/j.bbcan.2018.01.002 . Biochimica et biophysica acta. Reviews on cancer

Electrochemical Behavior of a Mitochondria-Targeted Antioxidant at an Interface between Two Immiscible Electrolyte Solutions: An Alternative Approach to Study Lipophilicity.

Ribeiro JA; Benfeito S; Cagide F; Teixeira J; Oliveira PJ; Borges F; Silva AF; Pereira CM, 2018. Analytical chemistry. 2018. http://europepmc.org/abstract/med/29863846 . 10.1021/acs.analchem.8b00787 . Analytical chemistry

Sources of hepatic glycogen synthesis in mice fed with glucose or fructose as the sole dietary carbohydrate.

Jarak I; Barosa C; Martins FO; Silva JCP; Santos C; Belew GD; Rito J; et al, 2018. Magnetic resonance in medicine. 2018. http://europepmc.org/abstract/med/30058123 . 10.1002/mrm.27378 . Magnetic resonance in medicine

Desrisking the Cytotoxicity of a Mitochondriotropic Antioxidant Based on Caffeic Acid by a PEGylated Strategy

Carlos Fernandes; Sofia Benfeito; Ricardo Amorim; José Teixeira; Paulo J. Oliveira; Fernando Remião; Fernanda Borges, 2018. Bioconjugate Chemistry. 2018. https://doi.org/10.1021/acs.bioconjchem.8b00383 . 10.1021/acs.bioconjchem.8b00383 . Bioconjugate Chemistry

Evaluation of Respiration with Clark-Type Electrode in Isolated Mitochondria and Permeabilized Animal Cells.

Silva AM; Oliveira PJ, 2018. Methods in molecular biology (Clifton, N.J.). 2018. http://europepmc.org/abstract/med/29850992 . 10.1007/978-1-4939-7831-1_2 . Methods in molecular biology (Clifton, N.J.)

Multi-target-directed ligands for Alzheimer's disease: Discovery of chromone-based monoamine oxidase/cholinesterase inhibitors.

Reis J; Cagide F; Valencia ME; Teixeira J; Bagetta D; Pérez C; Uriarte E; et al, 2018. European journal of medicinal chemistry. 2018. http://europepmc.org/abstract/med/30245401 . 10.1016/j.ejmech.2018.07.056 . European journal of medicinal chemistry

Mitochondria and Reactive Oxygen Species in Aging and Age-Related Diseases.

Giorgi C; Marchi S; Simoes ICM; Ren Z; Morciano G; Perrone M; Patalas-Krawczyk P; et al, 2018. International review of cell and molecular biology. 2018. http://europepmc.org/abstract/med/30072092 . 10.1016/bs.ircmb.2018.05.006 . International review of cell and molecular biology

Reactivation of Dihydroorotate Dehydrogenase-Driven Pyrimidine Biosynthesis Restores Tumor Growth of Respiration-Deficient Cancer Cells.

Bajzikova M; Kovarova J; Coelho AR; Boukalova S; Oh S; Rohlenova K; Svec D; et al, 2018. Cell metabolism. 2018. http://europepmc.org/abstract/med/30449682 . 10.1016/j.cmet.2018.10.014 . Cell metabolism

Disruption of mitochondrial function as mechanism for anti-cancer activity of a novel mitochondriotropic menadione derivative

Teixeira, J.; Amorim, R.; Santos, K.; Soares, P.; Datta, S.; Cortopassi, G.A.; Serafim, T.L.; et al, 2018. Toxicology. 123 - 139. 393. 2018. http://www.scopus.com/inward/record.url?eid=2-s2.0-85034013034&partnerID=MN8TOARS . 10.1016/j.tox.2017.11.014 . published Toxicology

Extracellular acidification induces ROS- and mPTP-mediated death in HEK293 cells

Teixeira, J.; Basit, F.; Swarts, H.G.; Forkink, M.; Oliveira, P.J.; Willems, P.H.G.M.; Koopman, W.J.H., 2018. Redox Biology. 394 - 404. 15. 2018. http://www.scopus.com/inward/record.url?eid=2-s2.0-85040366459&partnerID=MN8TOARS . 10.1016/j.redox.2017.12.018 . published Redox Biology

Discovery of a new mitochondria permeability transition pore (mPTP) inhibitor based on gallic acid

José Teixeira; Catarina Oliveira; Fernando Cagide; Ricardo Amorim; Jorge Garrido; Fernanda Borges; Paulo J. Oliveira, 2018. Journal of Enzyme Inhibition and Medicinal Chemistry. 567 - 576. 1. 33. 2018. https://doi.org/10.1080/14756366.2018.1442831 . 10.1080/14756366.2018.1442831 . published Journal of Enzyme Inhibition and Medicinal Chemistry

Mitochondria: Targeting mitochondrial reactive oxygen species with mitochondriotropic polyphenolic-based antioxidants.

Teixeira J; Deus CM; Borges F; Oliveira PJ, 2018. The international journal of biochemistry & cell biology. 2018. http://europepmc.org/abstract/med/29454114 . 10.1016/j.biocel.2018.02.007 . The international journal of biochemistry & cell biology

Hydroxybenzoic Acid Derivatives as Dual-Target Ligands: Mitochondriotropic Antioxidants and Cholinesterase Inhibitors.

Oliveira C; Cagide F; Teixeira J; Amorim R; Sequeira L; Mesiti F; Silva T; et al, 2018. Frontiers in chemistry. 2018. http://europepmc.org/abstract/med/29740575 . 10.3389/fchem.2018.00126 . Frontiers in chemistry

Metabolic and Phenotypic Characterization of Human Skin Fibroblasts After Forcing Oxidative Capacity.

Pereira SP; Deus CM; Serafim TL; Cunha-Oliveira T; Oliveira PJ, 2018. Toxicological sciences : an official journal of the Society of Toxicology. 2018. http://europepmc.org/abstract/med/29945227 . 10.1093/toxsci/kfy068 . Toxicological sciences : an official journal of the Society of Toxicology

Development of a PEGylated-Based Platform for Efficient Delivery of Dietary Antioxidants Across the Blood-Brain Barrier.

Fernandes C; Pinto M; Martins C; Gomes MJ; Sarmento B; Oliveira PJ; Remião F; Borges F, 2018. Bioconjugate chemistry. 2018. http://europepmc.org/abstract/med/29635917 . 10.1021/acs.bioconjchem.8b00151 . Bioconjugate chemistry

Toxicity of lupane derivatives on anionic membrane models, isolated rat mitochondria and selected human cell lines: Role of terminal alkyl chains

Filipa S. Carvalho; Catarina M. Morais; Jon Holy; Dmytro Krasutsky; Sergiy V. Yemets; Pavel A. Krasutsky; Amália S. Jurado; Paulo J. Oliveira; Teresa L. Serafim, 2018. Chemico-Biological Interactions. 198 - 210. 296. 2018. https://doi.org/10.1016/j.cbi.2018.10.002 . 10.1016/j.cbi.2018.10.002 . Chemico-Biological Interactions

Doxorubicin triggers bioenergetic failure and p53 activation in mouse stem cell-derived cardiomyocytes.

Cunha-Oliveira T; Ferreira LL; Coelho AR; Deus CM; Oliveira PJ, 2018. Toxicology and applied pharmacology. 2018. http://europepmc.org/abstract/med/29653124 . 10.1016/j.taap.2018.04.009 . Toxicology and applied pharmacology

SULFATION PATHWAYS: Potential benefits of a sulfated resveratrol derivative for topical application.

Correia-da-Silva M; Rocha V; Marques C; Deus CM; Marques-Carvalho A; Oliveira PJ; Palmeira A; et al, 2018. Journal of molecular endocrinology. 2018. http://europepmc.org/abstract/med/29588426 . 10.1530/jme-18-0031 . Journal of molecular endocrinology

Exercise and Doxorubicin Treatment Modulate Cardiac Mitochondrial Quality Control Signaling

Marques-Aleixo, I.; Santos-Alves, E.; Torrella, J. R.; Oliveira, P. J.; Magalhães, J.; Ascensão, A., 2017. Cardiovasc Toxicol. 2017. https://www.ncbi.nlm.nih.gov/pubmed/28536949 . 10.1007/s12012-017-9412-4 . Cardiovasc Toxicol

Altered mitochondrial epigenetics associated with subchronic doxorubicin cardiotoxicity

Ferreira, André; * Cunha-Oliveira, Teresa; Simões, Rui F.; Carvalho, Filipa S.; Burgeiro, Ana; Nordgren, Kendra; Wallace, Kendall B.; Oliveira, Paulo J., 2017. Toxicology. 63 - 73. 390. 2017. http://dx.doi.org/10.1016/j.tox.2017.08.011 . 10.1016/j.tox.2017.08.011 . published Toxicology

Response to "In silico prediction is insufficient to assess pathogenicity of mtDNA variants".

Bacalhau, M.; Pratas, J.; Simões, M.; Mendes, C.; Ribeiro, C.; Santos, MJ; Diogo, L.; Macário, MC; Grazina, Manuela (1F10-D85D-B592), 2017. European journal of medical genetics. 2017. http://europepmc.org/abstract/med/28807868 . 10.1016/j.ejmg.2017.08.008 . European journal of medical genetics

Glutaminemia prognostic significance in critical surgical patients – An analysis of plasma aminogram profile; Significado pronóstico de la glutaminemia en pacientes quirúrgicos críticos - Análisis del perfil del aminograma plasmático

Costa, Beatriz Pinto; Martins, Paulo; Verissimo, Carla; Simões, Marta; Tomé, Marisa; Grazina, Manuela; Pimentel, Jorge; Sousa, Francisco Castro, 2017. Nutrición Hospitalaria. 4. 34. 2017. http://dx.doi.org/10.20960/nh.817 . 10.20960/nh.817 . published Nutrición Hospitalaria

Intestinal dysfunction in the critical trauma patients – An early and frequent event

Costa, Beatriz Pinto; Martins, Paulo; Verissimo, Carla; Simões, Marta; Tomé, Marisa; Grazina, Manuela; Pimentel, Jorge; Castro-Sousa, Francisco, 2017. Nutrición Hospitalaria. 2. 34. 2017. http://dx.doi.org/10.20960/nh.788 . 10.20960/nh.788 . published Nutrición Hospitalaria

In silico analysis for predicting pathogenicity of five unclassified mitochondrial DNA mutations associated with mitochondrial cytopathies' phenotypes

Bacalhau, Mafalda; Pratas, João; Simões, Marta; Mendes, Cândida; Ribeiro, Carolina; Santos, Maria J.; Diogo, Luísa; Macário, Maria Carmo; Grazina, Manuela, 2017. European Journal of Medical Genetics. 172 - 177. 3. 60. 2017. http://dx.doi.org/10.1016/j.ejmg.2016.12.009 . 10.1016/j.ejmg.2016.12.009 . published European Journal of Medical Genetics

Genotyping CYP2D6 by three different methods: advantages and disadvantages

Ribeiro, Carolina; Martins, Patrícia; Grazina, Manuela, 2017. Drug Metabolism and Personalized Therapy. 1. 32. 2017. http://dx.doi.org/10.1515/dmpt-2016-0035 . 10.1515/dmpt-2016-0035 . published Drug Metabolism and Personalized Therapy

Dietary Polyphenols and Mitochondrial Function: Role in Health and Disease

Teixeira, J.; Chavarria, D.; Borges, F.; Wojtczak, L.; Wieckowski, M. R.; Karkucinska-Wieckowska, A.; Oliveira, P. J., 2017. Curr Med Chem. 2017. https://www.ncbi.nlm.nih.gov/pubmed/28554320 . 10.2174/0929867324666170529101810 . Curr Med Chem

Mitochondrial biology in cancer stem cells.

Loureiro R; Mesquita KA; Magalhães-Novais S; Oliveira PJ; Vega-Naredo I, 2017. Seminars in cancer biology. 2017. http://europepmc.org/abstract/med/28673608 . 10.1016/j.semcancer.2017.06.012 . Seminars in cancer biology

Association of p.Val158Met COMT polymorphism with paranoid ideation in drug addicts

Ribeiro, Carolina; Curto, João; Areias, Graça; Belo, Adriana; Balhau, João; Rocha Almeida, José; Grazina, Manuela, 2017. International Journal of Clinical Neurosciences and Mental Health. 4(Suppl. 3. 2017. http://dx.doi.org/10.21035/ijcnmh.2017.4(suppl.3).s12 . 10.21035/ijcnmh.2017.4(suppl.3).s12 . published International Journal of Clinical Neurosciences and Mental Health

Berberine-induced cardioprotection and Sirt3 modulation in doxorubicin-treated H9c2 cardiomyoblasts

Coelho, Ana R.; Martins, Tatiana R.; Couto, Renata; Deus, Cláudia; Pereira, Cláudia V.; Simões, Rui F.; Rizvanov, Albert A.; et al, 2017. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 2904 - 2923. 11. 1863. 2017. http://dx.doi.org/10.1016/j.bbadis.2017.07.030 . 10.1016/j.bbadis.2017.07.030 . published Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

Histone Deacetylase Inhibitors Protect Against Pyruvate Dehydrogenase Dysfunction in Huntington's Disease

Naia, Luana; * Cunha-Oliveira, Teresa; Rodrigues, Joana; Rosenstock, Tatiana R.; Oliveira, Ana; Ribeiro, Márcio; Carmo, Catarina; et al, 2017. The Journal of Neuroscience. 2776 - 2794. 10. 37. 2017. http://dx.doi.org/10.1523/jneurosci.2006-14.2016 . 10.1523/JNEUROSCI.2006-14.2016 . published The Journal of Neuroscience

Adenosine receptors: regulatory players in the preservation of mitochondrial function induced by ischemic preconditioning of rat liver

Duarte, F.V.; Amorim, J.A.; Varela, A.T.; Teodoro, J.S.; Gomes, A.P.; Cunha, R.A.; Palmeira, C.M.; et al, 2017. Purinergic Signalling. 179 - 190. 2. 13. 2017. http://www.scopus.com/inward/record.url?eid=2-s2.0-84995486129&partnerID=MN8TOARS . 10.1007/s11302-016-9548-x . Purinergic Signalling

Exposure to BDE-153 induces autophagy in HepG2 cells.

Pereira LC; Duarte FV; Varela ATIF; Rolo AP; Palmeira CMM; Dorta DJ, 2017. 2017. http://europepmc.org/abstract/med/28396260 . 10.1016/j.tiv.2017.04.005 .

Exposure to decabromodiphenyl ether (BDE-209) produces mitochondrial dysfunction in rat liver and cell death

Pereira, L.C.; Souza, A.O.; Tasso, M.J.; Oliveira, A.M.C.; Duarte, F.V.; Palmeira, C.M.; Dorta, D.J., 2017. Journal of Toxicology and Environmental Health - Part A: Current Issues. 1129 - 1144. 19-21. 80. 2017. http://www.scopus.com/inward/record.url?eid=2-s2.0-85033371791&partnerID=MN8TOARS . 10.1080/15287394.2017.1357370 . Journal of Toxicology and Environmental Health - Part A: Current Issues

Dietary Polyphenols and Mitochondrial Function: Role in Health and Disease

Teixeira, J.; Chavarria, D.; Borges, F.; Wojtczak, L.; Wieckowski, M. R.; Karkucinska-Wieckowska, A.; Oliveira, P. J., 2017. Curr Med Chem. 2017. https://www.ncbi.nlm.nih.gov/pubmed/28554320 . 10.2174/0929867324666170529101810 . published Curr Med Chem

Lack of additive effects of resveratrol and energy restriction in the treatment of hepatic steatosis in rats

Milton-Laskibar, I.; Aguirre, L.; Fernández-Quintela, A.; Rolo, A.P.; Teodoro, J.S.; Palmeira, C.M.; Portillo, M.P., 2017. Nutrients. 7. 9. 2017. http://www.scopus.com/inward/record.url?eid=2-s2.0-85023760594&partnerID=MN8TOARS . 10.3390/nu9070737 . Nutrients

European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS)

Egea, J.; Fabregat, I.; Frapart, Y.M.; Ghezzi, P.; Görlach, A.; Kietzmann, T.; Kubaichuk, K.; et al, 2017. Redox Biology. 94 - 162. 13. 2017. http://www.scopus.com/inward/record.url?eid=2-s2.0-85020032301&partnerID=MN8TOARS . 10.1016/j.redox.2017.05.007 . Redox Biology

GSK3ß and VDAC Involvement in ER Stress and Apoptosis Modulation during Orthotopic Liver Transplantation.

Zaouali MA; Panisello A; Lopez A; Castro C; Folch E; Carbonell T; Rolo A; et al, 2017. 2017. http://europepmc.org/abstract/med/28282906 . 10.3390/ijms18030591 .

Bioenergetic adaptations of the human liver in the ALPPS procedure – how liver regeneration correlates with mitochondrial energy status

Alexandrino, H.; Rolo, A.; Teodoro, J.S.; Donato, H.; Martins, R.; Serôdio, M.; Martins, M.; et al, 2017. HPB. 1091 - 1103. 12. 19. 2017. http://www.scopus.com/inward/record.url?eid=2-s2.0-85029605721&partnerID=MN8TOARS . 10.1016/j.hpb.2017.08.005 . HPB

Development of hydroxybenzoic-based platforms as a solution to deliver dietary antioxidants to mitochondria

Teixeira, J.; Oliveira, C.; Amorim, R.; Cagide, F.; Garrido, J.; Ribeiro, J.A.; Pereira, C.M.; et al, 2017. Scientific Reports. 1. 7. 2017. http://www.scopus.com/inward/record.url?eid=2-s2.0-85026475854&partnerID=MN8TOARS . 10.1038/s41598-017-07272-y . published Scientific Reports

Mitochondria in Excitatory and Inhibitory Synapses have Similar Susceptibility to Amyloid-ß Peptides Modeling Alzheimer's Disease

Amorim, J.A.; Canas, P.M.; Tomé, A.R.; Rolo, A.P.; Agostinho, P.; Palmeira, C.M.; Cunha, R.A., 2017. Journal of Alzheimer's Disease. 525 - 536. 2. 60. 2017. http://www.scopus.com/inward/record.url?eid=2-s2.0-85029613373&partnerID=MN8TOARS . 10.3233/JAD-170356 . Journal of Alzheimer's Disease

An autophagic process is activated in HepG2 cells to mediate BDE-100-induced toxicity.

Pereira LC; Duarte FV; Varela AT; Rolo AP; Palmeira CM; Dorta DJ, 2017. 2017. http://europepmc.org/abstract/med/27234317 . 10.1016/j.tox.2016.05.022 .

Development of a mitochondriotropic antioxidant based on caffeic acid: Proof of concept on cellular and mitochondrial oxidative stress models

Teixeira, J.; Cagide, F.; Benfeito, S.; Soares, P.; Garrido, J.; Baldeiras, I.; Ribeiro, J.A.; et al, 2017. Journal of Medicinal Chemistry. 7084 - 7098. 16. 60. 2017. http://www.scopus.com/inward/record.url?eid=2-s2.0-85028330575&partnerID=MN8TOARS . 10.1021/acs.jmedchem.7b00741 . published Journal of Medicinal Chemistry

Unacylated ghrelin prevents mitochondrial dysfunction in a model of ischemia/reperfusion liver injury

Rossetti, A.; Togliatto, G.; Rolo, A.P.; Teodoro, J.S.; Granata, R.; Ghigo, E.; Columbano, A.; Palmeira, C.M.; Brizzi, M.F., 2017. Cell Death Discovery. 1. 3. 2017. http://www.scopus.com/inward/record.url?eid=2-s2.0-85051289736&partnerID=MN8TOARS . 10.1038/cddiscovery.2017.77 . Cell Death Discovery

mtDNA copy number associated with age of onset in familial amyloid polyneuropathy

Santos, Diana; Santos, Maria João; Alves-Ferreira, Miguel; Coelho, Teresa; Sequeiros, Jorge; Alonso, Isabel; Oliveira, Pedro; et al, 2017. Journal of Neurology, Neurosurgery & Psychiatry. 300 - 304. 3. 89. 2017. http://dx.doi.org/10.1136/jnnp-2017-316657 . 10.1136/jnnp-2017-316657 . Journal of Neurology, Neurosurgery & Psychiatry

Carvedilol and antioxidant proteins in a type I diabetes animal model

Diogo, Catia V.; Deus, Claudia M.; Lebiedzinska-Arciszewska, Magdalena; Wojtala, Aleksandra; Wieckowski, Mariusz R.; Oliveira, Paulo J., 2017. European Journal of Clinical Investigation. 19 - 29. 1. 47. 2017. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000393880700002&KeyUID=WOS:000393880700002 . 10.1111/eci.12696 . European Journal of Clinical Investigation

Horizontal transfer of whole mitochondria restores tumorigenic potential in mitochondrial DNA-deficient cancer cells

Dong, L. F.; Kovarova, J.; Bajzikova, M.; Bezawork-Geleta, A.; Svec, D.; Endaya, B.; Sachaphibulkij, K.; et al, 2017. Elife. 6. 2017. https://www.ncbi.nlm.nih.gov/pubmed/28195532 . 10.7554/eLife.22187 . Elife

Protective Effect of Green Tea (Camellia sinensis (L.) Kuntze) against Prostate Cancer: From In Vitro Data to Algerian Patients

Lassed, Somia; Deus, Claudia M.; Djebbari, Radja; Zama, Djamila; Oliveira, Paulo J.; Rizvanov, Albert A.; Dahdouh, Abderrezak; Benayache, Fadila; Benayache, Samir, 2017. Evidence-Based Complementary and Alternative Medicine. 91568 - 91568. 2017. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000392530400001&KeyUID=WOS:000392530400001 . 10.1155/2017/1691568 . Evidence-Based Complementary and Alternative Medicine

Evaluation of biological properties of 3,3',4,4'-benzophenonetetracarboxylic dianhydride derivatives and their ability to inhibit hexokinase activity

Kochel, Krzysztof; Tomczyk, Mateusz D.; Simoes, Rui F.; Fraczek, Tomasz; Sobon, Adrian; Oliveira, Paulo J.; Walczak, Krzysztof Z.; et al, 2017. Bioorganic & Medicinal Chemistry Letters. 427 - 431. 3. 27. 2017. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000392900600010&KeyUID=WOS:000392900600010 . 10.1016/j.bmc1.2016.12.055 . Bioorganic & Medicinal Chemistry Letters

The pathophysiological role of cholecystokinin-1 receptor in mouse cholelithogenesis

Carbone, Federico; Oliveira, Paulo J.; Bonaventura, Aldo; Montecucco, Fabrizio, 2017. European Journal of Clinical Investigation. 195 - 196. 2. 47. 2017. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000393880500011&KeyUID=WOS:000393880500011 . 10.1111/eci.12713 . European Journal of Clinical Investigation

Flexible nanofilms coated with aligned piezoelectric microfibers preserve the contractility of cardiomyocytes

Gouveia, P. J.; Rosa, S.; Ricotti, L.; Abecasis, B.; Almeida, H. V.; Monteiro, L.; Nunes, J.; et al, 2017. Biomaterials. 213 - 228. 139. 2017. https://www.ncbi.nlm.nih.gov/pubmed/28622605 . 10.1016/j.biomaterials.2017.05.048 . Biomaterials

Development of a Mitochondriotropic Antioxidant Based on Caffeic Acid: Proof of Concept on Cellular and Mitochondrial Oxidative Stress Models

Teixeira, Jose; Cagide, Fernando; Benfeito, Sofia; Soares, Pedro; Garrido, Jorge; Baldeiras, Ines; Ribeiro, Jose A.; et al, 2017. Journal of Medicinal Chemistry. 7084 - 7098. 16. 60. 2017. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000408598500017&KeyUID=WOS:000408598500017 . 10.1021/acs.jmedchem.7b00741 . Journal of Medicinal Chemistry

Development of hydroxybenzoic-based platforms as a solution to deliver dietary antioxidants to mitochondria

Teixeira, Jose; Oliveira, Catarina; Amorim, Ricardo; Cagide, Fernando; Garrido, Jorge; Ribeiro, Jose A.; Pereira, Carlos M.; et al, 2017. Scientific Reports. 7. 2017. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000406610000093&KeyUID=WOS:000406610000093 . 10.1038/s41598-017-07272-y . Scientific Reports

Berberine-induced cardioprotection and Sirt3 modulation in doxorubicin-treated H9c2 cardiomyoblasts.

Coelho AR; Martins TR; Couto R; Deus C; Pereira CV; Simões RF; Rizvanov AA; et al, 2017. Biochimica et biophysica acta. Molecular basis of disease. 2017. http://europepmc.org/abstract/med/28760703 . 10.1016/j.bbadis.2017.07.030 . Biochimica et biophysica acta. Molecular basis of disease

The Nutraceutic Silybin Counteracts Excess Lipid Accumulation and Ongoing Oxidative Stress in an In Vitro Model of Non-Alcoholic Fatty Liver Disease Progression.

Vecchione G; Grasselli E; Cioffi F; Baldini F; Oliveira PJ; Sardão VA; Cortese K; et al, 2017. Frontiers in nutrition. 2017. http://europepmc.org/abstract/med/28971098 . 10.3389/fnut.2017.00042 . Frontiers in nutrition

Altered mitochondrial epigenetics associated with subchronic doxorubicin cardiotoxicity.

Ferreira A; Cunha-Oliveira T; Simões RF; Carvalho FS; Burgeiro A; Nordgren K; Wallace KB; Oliveira PJ, 2017. Toxicology. 2017. http://europepmc.org/abstract/med/28865727 . 10.1016/j.tox.2017.08.011 . Toxicology

Sirtuin 1-dependent resveratrol cytotoxicity and pro-differentiation activity on breast cancer cells

Deus, C. M.; Serafim, T. L.; Magalhães-Novais, S.; Vilaça, A.; Moreira, A. C.; Sardão, V. A.; Cardoso, S. M.; Oliveira, P. J., 2017. Arch Toxicol. 1261 - 1278. 3. 91. 2017. https://www.ncbi.nlm.nih.gov/pubmed/27358235 . 10.1007/s00204-016-1784-x . Arch Toxicol

Disruption of mitochondrial function as mechanism for anti-cancer activity of a novel mitochondriotropic menadione derivative.

Teixeira J; Amorim R; Santos K; Soares P; Datta S; Cortopassi GA; Serafim TL; et al, 2017. Toxicology. 2017. http://europepmc.org/abstract/med/29141199 . 10.1016/j.tox.2017.11.014 . Toxicology

Extracellular acidification induces ROS- and mPTP-mediated death in HEK293 cells.

Teixeira J; Basit F; Swarts HG; Forkink M; Oliveira PJ; Willems PHGM; Koopman WJH, 2017. Redox biology. 2017. http://europepmc.org/abstract/med/29331741 . 10.1016/j.redox.2017.12.018 . Redox biology

Targeting Mitochondria in Cardiovascular Diseases

Silva, Filomena S. G.; Simoes, Rui F.; Couto, Renata; Oliveira, Paulo J., 2016. Current Pharmaceutical Design. 5698 - 5717. 37. 22. 2016. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000388519800006&KeyUID=WOS:000388519800006 . 10.2174/1381612822666160822150243 . Current Pharmaceutical Design

Hematopoietic and Mesenchymal Stem Cells in Biomedical and Clinical Applications.

Rizvanov AA; Persson J; Sahin F; Bellusci S; Oliveira PJ, 2016. Stem cells international. 2016. http://europepmc.org/abstract/med/27999598 . 10.1155/2016/3157365 . Stem cells international

Determination of Metabolic Viability and Cell Mass Using a Tandem Resazurin/Sulforhodamine B Assay.

Silva FS; Starostina IG; Ivanova VV; Rizvanov AA; Oliveira PJ; Pereira SP, 2016. Current protocols in toxicology. 2016. http://europepmc.org/abstract/med/27145111 . 10.1002/cptx.1 . Current protocols in toxicology

Physical Exercise and Brain Mitochondrial Fitness: The Possible Role Against Alzheimer's Disease

Bernardo, T. C.; Marques-Aleixo, I.; Beleza, J.; Oliveira, P. J.; Ascensao, A.; Magalhaes, J., 2016. Brain Pathology. 648 - 663. 5. 26. 2016. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000384678400008&KeyUID=WOS:000384678400008 . 10.1111/bpa.12403 . Brain Pathology

Hepatic and skeletal muscle mitochondrial toxicity of chitosan oligosaccharides of normal and diabetic rats.

Teodoro JS; Gomes AP; Varela AT; Duarte FV; Rolo AP; Palmeira CM, 2016. 2016. http://europepmc.org/abstract/med/27790925 . 10.1080/15376516.2016.1222643 .

Evaluation of Polybrominated Diphenyl Ether Toxicity on HepG2 Cells - Hexabrominated Congener (BDE-154) Is Less Toxic than Tetrabrominated Congener (BDE-47).

Souza AO; Tasso MJ; Oliveira AM; Pereira LC; Duarte FV; Oliveira DP; Palmeira CM; Dorta DJ, 2016. 2016. http://europepmc.org/abstract/med/27060917 . 10.1111/bcpt.12598 .

Involvement of mitochondrial dysfunction in nefazodone-induced hepatotoxicity

Silva, Ana Marta; Barbosa, Inês A.; Seabra, Cátia; Beltrão, Nuno; Santos, Raquel; Vega-Naredo, Ignacio; Oliveira, Paulo J.; # Cunha-Oliveira, Teresa, 2016. Food and Chemical Toxicology. 148 - 158. 1. 94. 2016. http://dx.doi.org/10.1016/j.fct.2016.06.001 . 10.1016/j.fct.2016.06.001 . published Food and Chemical Toxicology

The bile acid chenodeoxycholic acid directly modulates metabolic pathways in white adipose tissue in vitro: insight into how bile acids decrease obesity.

Teodoro JS; Rolo AP; Jarak I; Palmeira CM; Carvalho RA, 2016. 2016. http://europepmc.org/abstract/med/27488269 . 10.1002/nbm.3583 .

Physical exercise mitigates doxorubicin-induced brain cortex and cerebellum mitochondrial alterations and cellular quality control signaling

Marques-Aleixo, I; Santos-Alves, E.; Balca, M. M.; Moreira; Oliveira, P. J.; Magalhaes, J.; Ascensao, A., 2016. Mitochondrion. 43 - 57. 26. 2016. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000370768100006&KeyUID=WOS:000370768100006 . 10.1016/j.mito.2015.12.002 . Mitochondrion

Establishing a new model for toxicological evaluation combining Sulforhodamine B and resazurin in human cells

Silva, F. S. G.; Starostina, I. G.; Ivanova, V. V.; Rizvanov, A. A.; Oliveira, P. J.; Pereira, S. P., 2016. European Journal of Clinical Investigation. 66 - 66. 46. 2016. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000375378000155&KeyUID=WOS:000375378000155 . European Journal of Clinical Investigation

Low-dose, subchronic exposure to silver nanoparticles causes mitochondrial alterations in Sprague-Dawley rats.

Teodoro JS; Silva R; Varela AT; Duarte FV; Rolo AP; Hussain S; Palmeira CM, 2016. 2016. http://europepmc.org/abstract/med/27171910 . 10.2217/nnm-2016-0049 .

Involvement of mitochondrial dysfunction in nefazodone-induced hepatotoxicity

Silva, Ana Marta; Barbosa, Ines A.; Seabra, Catia; Beltrao, Nuno; Santos, Raquel; Vega-Naredo, Ignacio; Oliveira, Paulo J.; Cunha-Oliveira, Teresa, 2016. Food and Chemical Toxicology. 148 - 158. 94. 2016. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000380414900016&KeyUID=WOS:000380414900016 . 10.1016/j.fct.2016.06.001 . Food and Chemical Toxicology

Exercise mitigates mitochondrial permeability transition pore and quality control mechanisms alterations in nonalcoholic steatohepatitis

Goncalves, Ines O.; Passos, Emanuel; Diogo, Catia V.; Rocha-Rodrigues, Silvia; Santos-Alves, Estela; Oliveira, Paulo J.; Ascensao, Antonio; Magalhaes, Jose, 2016. Applied Physiology Nutrition and Metabolism. 298 - 306. 3. 41. 2016. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000375441400010&KeyUID=WOS:000375441400010 . 10.1139/apnm-2015-0470 . Applied Physiology Nutrition and Metabolism

Cardiac cytochrome c and cardiolipin depletion during anthracycline-induced chronic depression of mitochondrial function

Pereira, Goncalo C.; Pereira, Susana P.; Tavares, Ludgero C.; Carvalho, Filipa S.; Magalhaes-Novais, Silvia; Barbosa, Ines A.; Santos, Maria S.; et al, 2016. Mitochondrion. 95 - 104. 30. 2016. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000384037300011&KeyUID=WOS:000384037300011 . 10.1016/j.mito.2016.07.005 . Mitochondrion

Diet, Lifestyles, Family History, and Prostate Cancer Incidence in an East Algerian Patient Group

Lassed, Somia; Deus, Claudia M.; Lourenco, Nuno; Dahdouh, Abderrezak; Rizvanov, Albert A.; Oliveira, Paulo J.; Zama, Djamila, 2016. Biomed Research International. 2016. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000387239100001&KeyUID=WOS:000387239100001 . 10.1155/2016/5730569 . Biomed Research International

Ketogenic diets: from cancer to mitochondrial diseases and beyond

Branco, Ana F.; Ferreira, André; Simões, Rui F.; Magalhães-Novais, Sílvia; Zehowski, Cheryl; Cope, Elisabeth; Silva, Ana Marta; et al, 2016. European Journal of Clinical Investigation. 285 - 298. 3. 46. 2016. http://dx.doi.org/10.1111/eci.12591 . 10.1111/eci.12591 . published European Journal of Clinical Investigation

Argininemia and plasma arginine bioavailability - predictive factors of mortality in the severe trauma patients?

Costa BP; Martins P; Veríssimo C; Simões M; Tomé M; Grazina M; Pimentel J; Castro-Sousa F, 2016. 2016. http://europepmc.org/abstract/med/27582779 . 10.1186/s12986-016-0118-6 .

Lethal Neonatal LTBL Associated with Biallelic EARS2 Variants: Case Report and Review of the Reported Neuroradiological Features.

Oliveira R; Sommerville EW; Thompson K; Nunes J; Pyle A; Grazina M; Chinnery PF; et al, 2016. JIMD Reports. 61 - 68. 33. 2016. http://europepmc.org/abstract/med/27571996 . 10.1007/8904_2016_581 . published JIMD Reports

Secondary coenzyme Q10 deficiencies in oxidative phosphorylation (OXPHOS) and non-OXPHOS disorders.

Yubero D; Montero R; Martín MA; Montoya J; Ribes A; Grazina M; Trevisson E; et al, 2016. 2016. http://europepmc.org/abstract/med/27374853 . 10.1016/j.mito.2016.06.007 .

Identification of a novel deletion in SURF1 gene: Heterogeneity in Leigh syndrome with COX deficiency.

Ribeiro C; do Carmo Macário M; Viegas AT; Pratas J; Santos MJ; Simões M; Mendes C; et al, 2016. 2016. http://europepmc.org/abstract/med/27756633 . 10.1016/j.mito.2016.10.004 .

Oleanolic, Ursolic, and Betulinic Acids as Food Supplements or Pharmaceutical Agents for Type 2 Diabetes: Promise or Illusion?

Silva, Filomena S. G.; Oliveira, Paulo J.; Duarte, Maria F., 2016. Journal of Agricultural and Food Chemistry. 2991 - 3008. 15. 64. 2016. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000374812700001&KeyUID=WOS:000374812700001 . 10.1021/acs.jafc.5b06021 . Journal of Agricultural and Food Chemistry

Relevance of the ancestry for the variability of the Drug-Metabolizing Enzymes CYP2C9, CYP2C19 and CYP2D6 polymorphisms in a multiethnic Costa Rican population

Céspedes-Garro, Carolina; Rodrigues-Soares, Fernanda; Jiménez-Arce, Gerardo; G. Naranjo, María-Eugenia; Tarazona-Santos, Eduardo; Fariñas, Humberto; Barrantes, Ramiro; Llerena, Adrián; CEIBA.FP Consortium for the Ibero-American Network of Pharmacogenomics RIBEF, 2016. Revista de Biología Tropical. 3. 64. 2016. http://dx.doi.org/10.15517/rbt.v64i3.20901 . 10.15517/rbt.v64i3.20901 . Revista de Biología Tropical

Mitochondrial bioenergetics and posthepatectomy liver dysfunction.

Alexandrino H; Varela AT; Teodoro JS; Martins MA; Rolo AP; Tralhão JG; Palmeira CM; Castro E Sousa F, 2016. 2016. http://europepmc.org/abstract/med/27138992 . 10.1111/eci.12639 .

Bisphenol A as epigenetic modulator: setting the stage for carcinogenesis?

Ferreira LL; Couto R; Oliveira PJ, 2015. 2015. http://europepmc.org/abstract/med/25524584 . 10.1111/eci.12362 .

Measuring Mitochondrial Membrane Potential with a Tetraphenylphosphonium-Selective Electrode.

Moreno AJ; Santos DL; Magalhães-Novais S; Oliveira PJ, 2015. Current protocols in toxicology. 2015. http://europepmc.org/abstract/med/26250398 . 10.1002/0471140856.tx2505s65 . Current protocols in toxicology

Bridging the gap between nature and antioxidant setbacks: delivering caffeic acid to mitochondria.

Teixeira J; Soares P; Benfeito S; Murphy MP; Oliveira PJ; Borges F, 2015. 2015. http://europepmc.org/abstract/med/25634268 . 10.1007/978-1-4939-2288-8_6 .

Protective role of necrostatin-1 in acute myocardial infarction.

Carbone F; Oliveira PJ; Montecucco F, 2015. European journal of clinical investigation. 2015. http://europepmc.org/abstract/med/26584011 . 10.1111/eci.12568 . European journal of clinical investigation

Metabolic evaluations of cancer metabolism by NMR-based stable isotope tracer methodologies.

Tavares LC; Jarak I; Nogueira FN; Oliveira PJ; Carvalho RA, 2015. 2015. http://europepmc.org/abstract/med/25524585 . 10.1111/eci.12358 .

Comment on 'mycophenolic acid attenuates the tumour necrosis factor-a-mediated proinflammatory response in endothelial cells by blocking the MAPK/NF-¿B and ROS pathways' by Olejarz et al.

Oliveira PJ, 2015. 2015. http://europepmc.org/abstract/med/25413447 . 10.1111/eci.12382 .

Physical exercise prior and during treatment reduces sub-chronic doxorubicin-induced mitochondrial toxicity and oxidative stress.

Marques-Aleixo I; Santos-Alves E; Mariani D; Rizo-Roca D; Padrão AI; Rocha-Rodrigues S; Viscor G; et al, 2015. 2015. http://europepmc.org/abstract/med/25446396 . 10.1016/j.mito.2014.10.008 .

Gene Expression Profiling of H9c2 Myoblast Differentiation towards a Cardiac-Like Phenotype.

Branco AF; Pereira SP; Gonzalez S; Gusev O; Rizvanov AA; Oliveira PJ, 2015. 2015. http://europepmc.org/abstract/med/26121149 . 10.1371/journal.pone.0129303 .

Analysis of pro-apoptotic protein trafficking to and from mitochondria.

Vega-Naredo I; Cunha-Oliveira T; Serafim TL; Sardao VA; Oliveira PJ, 2015. 2015. http://europepmc.org/abstract/med/25308496 . 10.1007/978-1-4939-1875-1_14 .

Effects of Moderate Global Maternal Nutrient Reduction on Fetal Baboon Renal Mitochondrial Gene Expression at 0.9 Gestation.

Pereira SP; Oliveira PJ; Tavares LC; Moreno AJ; Cox LA; Nathanielsz PW; Nijland MJ, 2015. 2015. http://europepmc.org/abstract/med/25761880 . 10.1152/ajprenal.00419.2014 .

Back to the future: transgenerational transmission of xenobiotic-induced epigenetic remodeling.

Jiménez-Chillarón JC; Nijland MJ; Ascensão AA; Sardão VA; Magalhães J; Hitchler MJ; Domann FE; Oliveira PJ, 2015. 2015. http://europepmc.org/abstract/med/25774863 . 10.1080/15592294.2015.1020267 .

Role of mtDNA-related mitoepigenetic phenomena in cancer

Ferreira, André; Serafim, Teresa L; Sardão, Vilma A; # Cunha-Oliveira, Teresa, 2015. European Journal of Clinical Investigation. 44 - 49. S1. 45. 2015. http://dx.doi.org/10.1111/eci.12359 . 10.1111/eci.12359 . published European Journal of Clinical Investigation

Melatonin antiproliferative effects require active mitochondrial function in embryonal carcinoma cells.

Loureiro R; Magalhães-Novais S; Mesquita KA; Baldeiras I; Sousa IS; Tavares LC; Barbosa IA; Oliveira PJ; Vega-Naredo I, 2015. 2015. http://europepmc.org/abstract/med/26025920 .

Shutting Down the Furnace: Preferential Killing of Cancer Cells with Mitochondrial-targeting Molecules.

Deus CM; Santos GL; Loureiro R; Vega-Naredo I; Faneca H; Oliveira PJ, 2015. 2015. http://europepmc.org/abstract/med/25666790 .

Cardiomyocyte H9c2 cells present a valuable alternative to fish lethal testing for azoxystrobin.

Rodrigues ET; Pardal MÂ; Laizé V; Cancela ML; Oliveira PJ; Serafim TL, 2015. 2015. http://europepmc.org/abstract/med/26319055 . 10.1016/j.envpol.2015.08.026 .

Activation of IGF-1 and Insulin Signaling Pathways Ameliorate Mitochondrial Function and Energy Metabolism in Huntington’s Disease Human Lymphoblasts

Naia, Luana; Ferreira, I. Luísa; Cunha-Oliveira, Teresa; Duarte, Ana I.; Ribeiro, Márcio; Rosenstock, Tatiana R.; Laço, Mário N.; et al, 2015. Molecular Neurobiology. 331 - 348. 1. 51. 2015. http://dx.doi.org/10.1007/s12035-014-8735-4 . 10.1007/s12035-014-8735-4 . published Molecular Neurobiology

Physical exercise improves brain cortex and cerebellum mitochondrial bioenergetics and alters apoptotic, dynamic and auto(mito)phagy markers.

Marques-Aleixo I; Santos-Alves E; Balça MM; Rizo-Roca D; Moreira PI; Oliveira PJ; Magalhães J; Ascensão A, 2015. 2015. http://europepmc.org/abstract/med/26116519 . 10.1016/j.neuroscience.2015.06.027 .

Stimulating basal mitochondrial respiration decreases doxorubicin apoptotic signaling in H9c2 cardiomyoblasts.

Deus CM; Zehowski C; Nordgren K; Wallace KB; Skildum A; Oliveira PJ, 2015. 2015. http://europepmc.org/abstract/med/25997894 . 10.1016/j.tox.2015.05.001 .

AS TOXICODEPENDÊNCIAS ¿ A PROCURA INCESSANTE DA FELICIDADE? / Drug addictions - the incessant search for happiness?

Grazina, Manuela, 2015. Adictologia. 8 - 9. 1. 2015. published Adictologia

Pharmacogenomics of cocaine addiction.

Grazina, Manuela; Macedo, C; Ribeiro, C.; Curto, J, 2015. Adictologia. 28 - 39. 1. 2015. published Adictologia

Pharmacogenetics in Central American healthy volunteers: interethnic variability.

Céspedes-Garro C; Naranjo ME; Ramírez R; Serrano V; Fariñas H; Barrantes R; LLerena A; CEIBA Consortium of the Ibero-American Network of Pharmacogenetics and Pharmacogenomics RIBEF, 2015. 2015. http://europepmc.org/abstract/med/25490028 .

Genetic Variation of MT-ND Genes in Frontotemporal Lobar Degeneration: Biochemical Phenotype-Genotype Correlation.

Gaspar R; Santana I; Mendes C; Fernandes AS; Duro D; Simões M; Luís D; Santos MJ; Grazina M, 2015. 2015. http://europepmc.org/abstract/med/25871488 . 10.1159/000380766 .

Measuring p66Shc Signaling Pathway Activation and Mitochondrial Translocation in Cultured Cells.

Wieckowski MR; Deus CM; Couto R; Oparka M; Lebiedzinska-Arciszewska M; Duszynski J; Oliveira PJ, 2015. Current protocols in toxicology. 2015. http://europepmc.org/abstract/med/26523473 . 10.1002/0471140856.tx2506s66 . Current protocols in toxicology

Exercise modulates liver cellular and mitochondrial proteins related to quality control signaling.

Santos-Alves E; Marques-Aleixo I; Rizo-Roca D; Torrella JR; Oliveira PJ; Magalhães J; Ascensão A, 2015. 2015. http://europepmc.org/abstract/med/26135624 . 10.1016/j.lfs.2015.06.007 .

p66Shc signaling is involved in stress responses elicited by anthracycline treatment of rat cardiomyoblasts.

Sampaio SF; Branco AF; Wojtala A; Vega-Naredo I; Wieckowski MR; Oliveira PJ; Sampaio, Susana F.; et al, 2015. Archives of Toxicology. 1669 - 1684. 7. 90. 2015. http://europepmc.org/abstract/med/26318906 . 10.1007/s00204-015-1583-9 . Archives of Toxicology

High frequency and founder effect of the CYP3A4*20 loss-of-function allele in the Spanish population classifies CYP3A4 as a polymorphic enzyme.

Apellániz-Ruiz M; Inglada-Pérez L; Naranjo ME; Sánchez L; Mancikova V; Currás-Freixes M; de Cubas AA; et al, 2015. 2015. http://europepmc.org/abstract/med/25348618 . 10.1038/tpj.2014.67 .

Losartan activates sirtuin 1 in rat reduced-size orthotopic liver transplantation.

Pantazi E; Bejaoui M; Zaouali MA; Folch-Puy E; Pinto Rolo A; Panisello A; Palmeira CM; Roselló-Catafau J, 2015. 2015. http://europepmc.org/abstract/med/26185373 . 10.3748/wjg.v21.i26.8021 .

Editorial: Metabolic Diseases: Drugs and Mitochondrial Targets.

Palmeira CM; Rolo AP; Palmeira, C.M.; Rolo, A.P., 2015. Current Medicinal Chemistry. 20. 22. 2015. http://europepmc.org/abstract/med/26549543 . 10.2174/092986732220150722123617 . Current Medicinal Chemistry

Biochemical and physiological responses of Carcinus maenas to temperature and the fungicide azoxystrobin.

Rodrigues ET; Moreno A; Mendes T; Palmeira C; Pardal MÂ, 2015. 2015. http://europepmc.org/abstract/med/25835271 . 10.1016/j.chemosphere.2015.03.011 .

Sirtuin 1 in rat orthotopic liver transplantation: an IGL-1 preservation solution approach.

Pantazi E; Zaouali MA; Bejaoui M; Folch-Puy E; Ben Abdennebi H; Varela AT; Rolo AP; Palmeira CM; Roselló-Catafau J, 2015. 2015. http://europepmc.org/abstract/med/25684941 . 10.3748/wjg.v21.i6.1765 .

Complex I and complex III inhibition specifically increase cytosolic hydrogen peroxide levels without inducing oxidative stress in HEK293 cells

Forkink, M.; Basit, F.; Teixeira, J.; Swarts, H.G.; Koopman, W.J.H.; Willems, P.H.G.M., 2015. Redox Biology. 607 - 616. 6. 2015. http://www.scopus.com/inward/record.url?eid=2-s2.0-84945395305&partnerID=MN8TOARS . 10.1016/j.redox.2015.09.003 . published Redox Biology

PPARa Agonist WY-14643 Induces SIRT1 Activity in Rat Fatty Liver Ischemia-Reperfusion Injury.

Pantazi E; Folch-Puy E; Bejaoui M; Panisello A; Varela AT; Rolo AP; Palmeira CM; Roselló-Catafau J, 2015. 2015. http://europepmc.org/abstract/med/26539534 . 10.1155/2015/894679 .

Impairment of mitochondrial energy metabolism of two marine fish by in vitro mercuric chloride exposure.

Mieiro CL; Pardal M; Duarte A; Pereira E; Palmeira CM, 2015. 2015. http://europepmc.org/abstract/med/26026249 . 10.1016/j.marpolbul.2015.05.054 .

The Emerging Role of MitomiRs in the Pathophysiology of Human Disease.

Duarte FV; Palmeira CM; Rolo AP, 2015. 2015. http://europepmc.org/abstract/med/26663182 . 10.1007/978-3-319-22671-2_8 .

Reactive oxygen species, nutrition, hypoxia and diseases: Problems solved?

Görlach A; Dimova EY; Petry A; Martínez-Ruiz A; Hernansanz-Agustín P; Rolo AP; Palmeira CM; Kietzmann T, 2015. 2015. http://europepmc.org/abstract/med/26339717 . 10.1016/j.redox.2015.08.016 .

Regulation of Mitochondrial Function and its Impact in Metabolic Stress.

Duarte FV; Amorim JA; Palmeira CM; Rolo AP, 2015. 2015. http://europepmc.org/abstract/med/25973983 . 10.2174/0929867322666150514095910 .

Modulation of cardiac mitochondrial permeability transition and apoptotic signaling by endurance training and intermittent hypobaric hypoxia

Magalhães, J.; Gonçalves, I. O.; Lumini-Oliveira, J.; Marques-Aleixo, I.; Passos, E.; Rocha-Rodrigues, S.; Machado, N. G.; et al, 2014. Int J Cardiol. 2014. 10.1016/j.ijcard.2014.02.011 . Int J Cardiol

Carriers for metal complexes on tumour cells: the effect of cyclodextrins vs CNTs on the model guest phenanthroline-5,6-dione trithiacyclononane ruthenium(II) chloride

Braga, S. S.; Marques, J.; Heister, E.; Diogo, C. V.; Oliveira, P. J.; Paz, F. A.; Santos, T. M.; Marques, M. P., 2014. Biometals. 2014. 10.1007/s10534-014-9725-8 . Biometals

Physical exercise prevents and mitigates non-alcoholic steatohepatitis-induced liver mitochondrial structural and bioenergetics impairments.

Gonçalves IO; Passos E; Rocha-Rodrigues S; Diogo CV; Torrella JR; Rizo D; Viscor G; et al, 2014. 2014. http://europepmc.org/abstract/med/24727595 . 10.1016/j.mito.2014.03.012 .

High-fat and obesogenic diets: current and future strategies to fight obesity and diabetes.

Teodoro JS; Varela AT; Rolo AP; Palmeira CM, 2014. 2014. http://europepmc.org/abstract/med/24842072 . 10.1007/s12263-014-0406-6 .

Enhancement of brown fat thermogenesis using chenodeoxycholic acid in mice.

Teodoro JS; Zouhar P; Flachs P; Bardova K; Janovska P; Gomes AP; Duarte FV; et al, 2014. 2014. http://europepmc.org/abstract/med/24310401 . 10.1038/ijo.2013.230 .

Ethnic background and CYP2D6 genetic polymorphisms in Costa Ricans

Céspedes-Garro, Carolina; Jiménez-Arce, Gerardo; Naranjo, María-Eugenia G.; Barrantes, Ramiro; LLerena, Adrián; Institucional, Autor, 2014. Revista de Biología Tropical. 4. 62. 2014. http://dx.doi.org/10.15517/rbt.v62i4.12916 . 10.15517/rbt.v62i4.12916 . Revista de Biología Tropical

ß-adrenergic over-stimulation and cardio-myocyte apoptosis: two receptors, one organelle, two fates?

Branco AF; Moreira AC; Cunha-Oliveira T; Couto R; Sardao VA; Rizvanov AA; Palotas A; Oliveira PJ, 2014. Current drug targets. 2014. http://europepmc.org/abstract/med/25182471 . 10.2174/1389450115666140902124230 . Current drug targets

Mitochondrial apoptosis-inducing factor is involved in doxorubicin-induced toxicity on H9c2 cardiomyoblasts

Moreira, Ana C; Branco, Ana F; Sampaio, Susana F; Cunha-Oliveira, Teresa; Martins, Tatiana R; Holy, Jon; Oliveira, Paulo J; et al, 2014. Biochimica et Biophysica Acta-Molecular Basis of Disease. 2468 - 2478. 12. 1842. 2014. http://hdl.handle.net/10316/41109 . 10.1016/j.bbadis.2014.09.015 . published Biochimica et Biophysica Acta-Molecular Basis of Disease

Targeting mitochondrial function for the treatment of breast cancer.

Deus CM; Coelho AR; Serafim TL; Oliveira PJ, 2014. 2014. http://europepmc.org/abstract/med/25365234 . 10.4155/fmc.14.100 .

Mitochondrial metabolism directs stemness and differentiation in P19 embryonal carcinoma stem cells.

Vega-Naredo I; Loureiro R; Mesquita KA; Barbosa IA; Tavares LC; Branco AF; Erickson JR; et al, 2014. 2014. http://europepmc.org/abstract/med/24832466 . 10.1038/cdd.2014.66 .

Exercise mitigates diclofenac-induced liver mitochondrial dysfunction.

Santos-Alves E; Marques-Aleixo I; Coxito P; Balça MM; Rizo-Roca D; Rocha-Rodrigues S; Martins S; et al, 2014. 2014. http://europepmc.org/abstract/med/24889192 . 10.1111/eci.12285 .

Exercise alters liver mitochondria phospholipidomic profile and mitochondrial activity in non-alcoholic steatohepatitis.

Gonçalves IO; Maciel E; Passos E; Torrella JR; Rizo D; Viscor G; Rocha-Rodrigues S; et al, 2014. 2014. http://europepmc.org/abstract/med/25063232 . 10.1016/j.biocel.2014.07.011 .

Mitochondrial apoptosis-inducing factor is involved in doxorubicin-induced toxicity on H9c2 cardiomyoblasts.

Moreira AC; Branco AF; Sampaio SF; Cunha-Oliveira T; Martins TR; Holy J; Oliveira PJ; Sardão VA, 2014. 2014. http://europepmc.org/abstract/med/25283819 . 10.1016/j.bbadis.2014.09.015 .

Metabolic effects of hypoxia in colorectal cancer by 13C NMR isotopomer analysis

Abrantes, A.M.; Tavares, L.C.; Pires, S.; Casalta-Lopes, J.; Mendes, C.; Simões, M.; Grazina, M.M.; Carvalho, R.A.; Botelho, M.F., 2014. BioMed Research International. 2014. 2014. http://www.scopus.com/inward/record.url?eid=2-s2.0-84904819813&partnerID=MN8TOARS . 10.1155/2014/759791 . BioMed Research International

Mitochondrial membrane lipids in life and death and their molecular modulation by diet: tuning the furnace.

Monteiro JP; Morais CM; Oliveira PJ; Jurado AS, 2014. Current drug targets. 2014. http://europepmc.org/abstract/med/24953065 . 10.2174/1389450115666140623115315 . Current drug targets

Vital imaging of multicellular spheroids

Oliveira, P. J.; Perkins, E. L.; Holy, J., 2014. Methods Mol Biol. 227 - 41. 1075. 2014. 10.1007/978-1-60761-847-8_11 . Methods Mol Biol

ß-adrenergic over-stimulation and cardio-myocyte apoptosis: two receptors, one organelle, two fates?

Branco, Ana F; Moreira, Ana C; Cunha-Oliveira, Teresa; Couto, Renata; Sardao, Vilma A; Rizvanov, Albert A; Palotas, Andras; et al, 2014. Current Drug Targets. 956 - 964. 10. 15. 2014. http://dx.doi.org/10.2174/1389450115666140902124230 . 10.2174/1389450115666140902124230 . published Current Drug Targets

Doxorubicin-Induced Cardiotoxicity: From Bioenergetic Failure and Cell Death to Cardiomyopathy

Carvalho, Filipa S.; Burgeiro, Ana; Garcia, Rita; Moreno, Antonio J.; Carvalho, Rui A.; Oliveira, Paulo J., 2014. Medicinal Research Reviews. 106 - 135. 1. 34. 2014. 10.1002/med.21280 . Medicinal Research Reviews

The P2X7 receptor antagonist Brilliant Blue G attenuates contralateral rotations in a rat model of Parkinsonism through a combined control of synaptotoxicity, neurotoxicity and gliosis.

Carmo MR; Menezes AP; Nunes AC; Pliássova A; Rolo AP; Palmeira CM; Cunha RA; Canas PM; Andrade GM, 2014. 2014. http://europepmc.org/abstract/med/24508709 . 10.1016/j.neuropharm.2014.01.045 .

New derivatives of lupane triterpenoids disturb breast cancer mitochondria and induce cell death.

Serafim TL; Carvalho FS; Bernardo TC; Pereira GC; Perkins E; Holy J; Krasutsky DA; et al, 2014. 2014. http://europepmc.org/abstract/med/25245673 . 10.1016/j.bmc.2014.08.013 .

Differential immuno-reactivity to genomic DNA, RNA and mitochondrial DNA is associated with auto-immunity.

Ivanova VV; Khaiboullina SF; Cherenkova EE; Martynova EV; Nevzorova TA; Kunst MA; Sibgatullin TB; et al, 2014. 2014. http://europepmc.org/abstract/med/25562166 . 10.1159/000369663 .

The Role of microRNAs in Mitochondria: Small Players Acting Wide.

Duarte FV; Palmeira CM; Rolo AP, 2014. 2014. http://europepmc.org/abstract/med/25264560 . 10.3390/genes5040865 .

Alzheimer's disease, enzyme targets and drug discovery struggles: From natural products to drug prototypes

Silva, T.; Reis, J.; Teixeira, J.; Borges, F., 2014. Ageing Research Reviews. 116 - 145. 1. 15. 2014. http://www.scopus.com/inward/record.url?eid=2-s2.0-84899683262&partnerID=MN8TOARS . 10.1016/j.arr.2014.03.008 . published Ageing Research Reviews

Mitochondrial Cumulative Damage Induced by Mitoxantrone: Late Onset Cardiac Energetic Impairment.

Rossato LG; Costa VM; Dallegrave E; Arbo M; Silva R; Ferreira R; Amado F; et al, 2013. 2013. http://europepmc.org/abstract/med/24096626 . 10.1007/s12012-013-9230-2 .

Cumulative Mitoxantrone-induced Haematological and Hepatic Adverse Effects in a Sub-Chronic In Vivo Study.

Rossato LG; Costa VM; Dallegrave E; Arbo M; Dinis-Oliveira RJ; Santos-Silva A; Duarte JA; et al, 2013. 2013. http://europepmc.org/abstract/med/24119282 . 10.1111/bcpt.12143 .

Declining NAD(+) induces a pseudohypoxic state disrupting nuclear-mitochondrial communication during aging.

Gomes AP; Price NL; Ling AJ; Moslehi JJ; Montgomery MK; Rajman L; White JP; et al, 2013. 2013. http://europepmc.org/abstract/med/24360282 . 10.1016/j.cell.2013.11.037 .

Berberine reverts hepatic mitochondrial dysfunction in high-fat fed rats: A possible role for SirT3 activation

Teodoro, J.S.; Duarte, F.V.; Gomes, A.P.; Varela, A.T.; Peixoto, F.M.; Rolo, A.P.; Palmeira, C.M., 2013. Mitochondrion. 637 - 646. 6. 13. 2013. http://www.scopus.com/inward/record.url?eid=2-s2.0-84884937949&partnerID=MN8TOARS . 10.1016/j.mito.2013.09.002 . Mitochondrion

Inhibition of mitochondrial complex III blocks neuronal differentiation and maintains embryonic stem cell pluripotency.

Pereira SL; Grãos M; Rodrigues AS; Anjo SI; Carvalho RA; Oliveira PJ; Arenas E; Ramalho-Santos J, 2013. 2013. http://europepmc.org/abstract/med/24312632 . 10.1371/journal.pone.0082095 .

Therapeutic concentrations of mitoxantrone elicit energetic imbalance in H9c2 cells as an earlier event

Rossato, L.G.; Costa, V.M.; Vilas-Boas, V.; De Lourdes Bastos, M.; Rolo, A.; Palmeira, C.; Remião, F., 2013. Cardiovascular Toxicology. 413 - 425. 4. 13. 2013. http://www.scopus.com/inward/record.url?eid=2-s2.0-84890559945&partnerID=MN8TOARS . 10.1007/s12012-013-9224-0 . Cardiovascular Toxicology

Mitochondrial and liver oxidative stress alterations induced by N-butyl-N-(4-hydroxybutyl)nitrosamine: relevance for hepatotoxicity

Oliveira, Maria M.; Teixeira, Jose C.; Vasconcelos-Nobrega, Carmen; Felix, Luis M.; Sardao, Vilma A.; Colaco, Aura A.; Oliveira, Paula A.; Peixoto, Francisco P., 2013. Journal of Applied Toxicology. 434 - 443. 6. 33. 2013. 10.1002/jat.1763 . published Journal of Applied Toxicology

Dibenzofuran-induced mitochondrial dysfunction: Interaction with ANT carrier

Duarte, F.V.; Gomes, A.P.; Teodoro, J.S.; Varela, A.T.; Moreno, A.J.M.; Rolo, A.P.; Palmeira, C.M., 2013. Toxicology in Vitro. 2160 - 2168. 8. 27. 2013. http://www.scopus.com/inward/record.url?eid=2-s2.0-84885795993&partnerID=MN8TOARS . 10.1016/j.tiv.2013.08.009 . Toxicology in Vitro

Mitochondrial membrane lipid remodeling in pathophysiology: a new target for diet and therapeutic interventions.

Monteiro JP; Oliveira PJ; Jurado AS, 2013. 2013. http://europepmc.org/abstract/med/23827885 . 10.1016/j.plipres.2013.06.002 .

Exploring nature profits: Development of novel and potent lipophilic antioxidants based on galloyl-cinnamic hybrids

Teixeira, J.; Silva, T.; Benfeito, S.; Gaspar, A.; Garrido, E.M.; Garrido, J.; Borges, F., 2013. European Journal of Medicinal Chemistry. 289 - 296. 62. 2013. http://www.scopus.com/inward/record.url?eid=2-s2.0-84873030904&partnerID=MN8TOARS . 10.1016/j.ejmech.2012.12.049 . published European Journal of Medicinal Chemistry

Ipilimumab and vemurafenib: two different routes for targeting melanoma.

Burgeiro A; Mollinedo F; Oliveira PJ, 2013. 2013. http://europepmc.org/abstract/med/23862981 . 10.2174/15680096113139990080 .

Exercise as a therapeutic tool to prevent mitochondrial degeneration in nonalcoholic steatohepatitis.

Gonçalves IO; Oliveira PJ; Ascensão A; Magalhães J, 2013. European journal of clinical investigation. 2013. http://europepmc.org/abstract/med/24033085 . 10.1111/eci.12146 . European journal of clinical investigation

Biological insight, high-throughput datasets and the nature of neuro-degenerative disorders.

Valente AX; Oliveira PJ; Khaiboullina SF; Palotás A; Rizvanov AA, 2013. 2013. http://europepmc.org/abstract/med/23937175 . 10.2174/13892002113149990100 .

Mitochondria in cancer stem cells: a target for therapy.

Loureiro R; Mesquita KA; Oliveira PJ; Vega-Naredo I, 2013. 2013. http://europepmc.org/abstract/med/23360288 . 10.2174/18722148113079990006 .

Eccentric exercise transiently affects mice skeletal muscle mitochondrial function

Magalhaes, Jose; Fraga, Marta; Lumini-Oliveira, Jose; Goncalves, Ines; Costa, Manoel; Ferreira, Rita; Oliveira, Paulo J.; Ascensao, Antonio, 2013. Applied Physiology Nutrition and Metabolism-Physiologie Appliquee Nutrition Et Metabolisme. 401 - 409. 4. 38. 2013. 10.1139/apnm-2012-0226 . Applied Physiology Nutrition and Metabolism-Physiologie Appliquee Nutrition Et Metabolisme

Rapid human melanoma cell death induced by sanguinarine through oxidative stress

Burgeiro, A., 2013. European Journal of Pharmacology. 109 - 118. 1-3. 705. 2013. http://www.scopus.com/inward/record.url?eid=2-s2.0-84875293604&partnerID=MN8TOARS . 10.1016/j.ejphar.2013.02.035 . European Journal of Pharmacology

Disrupted ATP synthase activity and mitochondrial hyperpolarisation- dependent oxidative stress is associated with p66Shc phosphorylation in fibroblasts of NARP patients

Lebiedzinska, M., 2013. International Journal of Biochemistry and Cell Biology. 141 - 150. 1. 45. 2013. http://www.scopus.com/inward/record.url?eid=2-s2.0-84870685606&partnerID=MN8TOARS . 10.1016/j.biocel.2012.07.020 . International Journal of Biochemistry and Cell Biology

Cardiac mitochondrial dysfunction during hyperglycemia - The role of oxidative stress and p66Shc signaling

Diogo, C.V., 2013. International Journal of Biochemistry and Cell Biology. 114 - 122. 1. 45. 2013. http://www.scopus.com/inward/record.url?eid=2-s2.0-84870696911&partnerID=MN8TOARS . 10.1016/j.biocel.2012.07.004 . International Journal of Biochemistry and Cell Biology

Oxidative Stress and Drugs of Abuse: An Update

# Cunha-Oliveira, Teresa; Rego, A. Cristina; Oliveira, Catarina R., 2013. Mini-Reviews in Organic Chemistry. 321 - 334. 4. 10. 2013. http://dx.doi.org/10.2174/1570193X113106660026 . 10.2174/1570193X113106660026 . published Mini-Reviews in Organic Chemistry

Nonketotic hyperglycinemia: A cause of encephalopathy in children

Veríssimo, C.; Garcia, P.; Simões, M.; Robalo, C.; Henriques, R.; Diogo, L.; Grazina, M., 2013. Journal of Child Neurology. 251 - 254. 2. 28. 2013. http://www.scopus.com/inward/record.url?eid=2-s2.0-84872867628&partnerID=MN8TOARS . 10.1177/0883073812441063 . Journal of Child Neurology

Characterization of CYP2D6 genotypes and metabolic profiles in the Portuguese population: Pharmacogenetic implications

Albuquerque, J.; Ribeiro, C.; Naranjo, M.E.G.; Llerena, A.; Grazina, M., 2013. Personalized Medicine. 709 - 718. 7. 10. 2013. http://www.scopus.com/inward/record.url?eid=2-s2.0-84884149194&partnerID=MN8TOARS . 10.2217/pme.13.56 . Personalized Medicine

Antioxidant therapy: Still in search of the 'magic bullet'

Benfeito, S.; Oliveira, C.; Soares, P.; Fernandes, C.; Silva, T.; Teixeira, J.; Borges, F., 2013. Mitochondrion. 427 - 435. 5. 13. 2013. http://www.scopus.com/inward/record.url?eid=2-s2.0-84882877558&partnerID=MN8TOARS . 10.1016/j.mito.2012.12.002 . published Mitochondrion

Long term cortical plasticity in visual retinotopic areas in humans with silent retinal ganglion cell loss

d'Almeida, O.C.; Mateus, C.; Reis, A.; Grazina, M.M.; Castelo-Branco, M., 2013. NeuroImage. 222 - 230. 81. 2013. http://www.scopus.com/inward/record.url?eid=2-s2.0-84878825124&partnerID=MN8TOARS . 10.1016/j.neuroimage.2013.05.032 . NeuroImage

Reprint of: Revisiting oxidative stress and mitochondrial dysfunction in the pathogenesis of Parkinson disease—resemblance to the effect of amphetamine drugs of abuse

Perfeito, Rita; * Cunha-Oliveira, Teresa; Rego, Ana Cristina, 2013. Free Radical Biology and Medicine. 186 - 201. 62. 2013. http://dx.doi.org/10.1016/j.freeradbiomed.2013.05.042 . 10.1016/j.freeradbiomed.2013.05.042 . published Free Radical Biology and Medicine

Dimethylaminopyridine derivatives of lupane triterpenoids cause mitochondrial disruption and induce the permeability transition

Bernardo, Telma C.; Cunha-Oliveira, Teresa; Serafim, Teresa L.; Holy, Jon; Krasutsky, Dmytro; Kolomitsyna, Oksana; Krasutsky, Pavel; Moreno, António M.; Oliveira, Paulo J., 2013. Bioorganic & Medicinal Chemistry. 7239 - 7249. 23. 21. 2013. http://dx.doi.org/10.1016/j.bmc.2013.09.066 . 10.1016/j.bmc.2013.09.066 . published Bioorganic & Medicinal Chemistry

Rapeseed oil-rich diet alters in vitro menadione and nimesulide hepatic mitochondrial toxicity.

Monteiro JP; Silva AM; Jurado AS; Oliveira PJ, 2013. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2013. http://europepmc.org/abstract/med/23933359 . 10.1016/j.fct.2013.07.073 . Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association

CYP2D6-1584C>G promoter polymorphism and debrisoquine ultrarapid hydroxylation in healthy volunteers

Llerena, A.; Dorado, P.; Ramírez, R.; Calzadilla, L.R.; Peñas-Lledó, E.; Álvarez, M.; Naranjo, M.E.; González, I.; Pérez, B., 2013. Pharmacogenomics. 1973 - 1977. 16. 14. 2013. http://www.scopus.com/inward/record.url?eid=2-s2.0-84889046926&partnerID=MN8TOARS . 10.2217/pgs.13.181 . Pharmacogenomics

Uncovering the beginning of diabetes: the cellular redox status and oxidative stress as starting players in hyperglycemic damage.

Teodoro JS; Gomes AP; Varela AT; Duarte FV; Rolo AP; Palmeira CM, 2013. 2013. http://europepmc.org/abstract/med/23292031 . 10.1007/s11010-012-1555-9 .

Evaluation of drug-metabolizing enzyme hydroxylation phenotypes in Hispanic populations: The CEIBA cocktail

De Andrés, F.; Sosa-Macías, M.; Lazalde-Ramos, B.P.; Naranjo, M.E.G.; Tarazona-Santos, E.; Llerena, A.; Moya, G.E.; et al, 2013. Drug Metabolism and Drug Interactions. 135 - 146. 3. 28. 2013. http://www.scopus.com/inward/record.url?eid=2-s2.0-84888082961&partnerID=MN8TOARS . 10.1515/dmdi-2013-0020 . Drug Metabolism and Drug Interactions

Hydroxycinnamic acid antioxidants: An electrochemical overview

Teixeira, J.; Gaspar, A.; Garrido, E.M.; Garrido, J.; Borges, F., 2013. BioMed Research International. 2013. 2013. http://www.scopus.com/inward/record.url?eid=2-s2.0-84881540701&partnerID=MN8TOARS . 10.1155/2013/251754 . published BioMed Research International

Rapeseed oil-rich diet alters hepatic mitochondrial membrane lipid composition and disrupts bioenergetics.

Monteiro JP; Pereira CV; Silva AM; Maciel E; Baldeiras I; Peixoto F; Domingues MR; Jurado AS; Oliveira PJ, 2013. 2013. http://europepmc.org/abstract/med/23636270 . 10.1007/s00204-013-1068-7 .

Mitochondrial complex I dysfunction induced by cocaine and cocaine plus morphine in brain and liver mitochondria

# Cunha-Oliveira, Teresa; Silva, Lisbeth; Silva, Ana Maria; Moreno, António J.; Oliveira, Catarina R.; Santos, Maria S., 2013. Toxicology Letters. 298 - 306. 3. 219. 2013. http://dx.doi.org/10.1016/j.toxlet.2013.03.025 . 10.1016/j.toxlet.2013.03.025 . published Toxicology Letters

Alzheimer's disease and antioxidant therapy: How long how far?

Teixeira, J.; Silva, T.; Andrade, P.B.; Borges, F., 2013. Current Medicinal Chemistry. 2939 - 2952. 24. 20. 2013. http://www.scopus.com/inward/record.url?eid=2-s2.0-84880283997&partnerID=MN8TOARS . 10.2174/1871523011320240001 . published Current Medicinal Chemistry

The metabolic profile of mitoxantrone and its relation with mitoxantrone-induced cardiotoxicity.

Rossato LG; Costa VM; de Pinho PG; Arbo MD; de Freitas V; Vilain L; de Lourdes Bastos M; Palmeira C; Remião F, 2013. 2013. http://europepmc.org/abstract/med/23545721 . 10.1007/s00204-013-1040-6 .

Breath tests with novel 13c-substrates for clinical studies of liver mitochondrial function in health and disease.

Grattagliano I; Bonfrate L; Oliveira PJ; Castorani L; Ruggiero V; Valenzano AT; Ascensão A; Buzoianu A; Portincasa P, 2013. 2013. http://europepmc.org/abstract/med/24443072 .

Alzheimer's disease, cholesterol, and statins: The junctions of important metabolic pathways

Silva, T.; Teixeira, J.; Remião, F.; Borges, F., 2013. Angewandte Chemie - International Edition. 1110 - 1121. 4. 52. 2013. http://www.scopus.com/inward/record.url?eid=2-s2.0-84872382364&partnerID=MN8TOARS . 10.1002/anie.201204964 . published Angewandte Chemie - International Edition

Dimethylaminopyridine derivatives of lupane triterpenoids cause mitochondrial disruption and induce the permeability transition.

Bernardo TC; Cunha-Oliveira T; Serafim TL; Holy J; Krasutsky D; Kolomitsyna O; Krasutsky P; Moreno AM; Oliveira PJ, 2013. 2013. http://europepmc.org/abstract/med/24156937 . 10.1016/j.bmc.2013.09.066 .

Modulation of hepatic redox status and mitochondrial metabolism by exercise: therapeutic strategy for liver diseases.

Ascensão A; Martins MJ; Santos-Alves E; Gonçalves IO; Portincasa P; Oliveira PJ; Magalhães J, 2013. 2013. http://europepmc.org/abstract/med/23880173 . 10.1016/j.mito.2013.07.002 .

The NAD ratio redox paradox: why does too much reductive power cause oxidative stress?

Teodoro JS; Rolo AP; Palmeira CM, 2013. 2013. http://europepmc.org/abstract/med/23256455 . 10.3109/15376516.2012.759305 .

Coenzyme Q10 deficiency in mitochondrial DNA depletion syndromes

Montero, R.; Grazina, M.; López-Gallardo, E.; Montoya, J.; Briones, P.; Navarro-Sastre, A.; Land, J.M.; et al, 2013. Mitochondrion. 337 - 341. 4. 13. 2013. http://www.scopus.com/inward/record.url?eid=2-s2.0-84877800522&partnerID=MN8TOARS . 10.1016/j.mito.2013.04.001 . Mitochondrion

Synergistic impact of endurance training and intermittent hypobaric hypoxia on cardiac function and mitochondrial energetic and signaling.

Magalhães J; Falcão-Pires I; Gonçalves IO; Lumini-Oliveira J; Marques-Aleixo I; Dos Passos E; Rocha-Rodrigues S; et al, 2013. 2013. http://europepmc.org/abstract/med/24012275 . 10.1016/j.ijcard.2013.08.001 .

A biophysical approach to menadione membrane interactions: Relevance for menadione-induced mitochondria dysfunction and related deleterious/therapeutic effects

Monteiro, Joao P.; Martins, Andre F.; Nunes, Claudia; Morais, Catarina M.; Lucio, Marlene; Reis, Salette; Pinheiro, Teresa J. T.; et al, 2013. Biochimica Et Biophysica Acta-Biomembranes. 1899 - 1908. 8. 1828. 2013. 10.1016/j.bbamem.2013.04.006 . Biochimica Et Biophysica Acta-Biomembranes

A silybin-phospholipids complex counteracts rat fatty liver degeneration and mitochondrial oxidative changes

Grattagliano, Ignazio; Diogo, Catia V.; Mastrodonato, Maria; de Bari, Ornella; Persichella, Michele; Wang, David Q. H.; Liquori, Adriana; et al, 2013. World Journal of Gastroenterology. 3007 - 3017. 20. 19. 2013. 10.3748/wjg.v19.i20.3007 . World Journal of Gastroenterology

Combined effects of aging and in vitro non-steroid anti-inflammatory drugs on kidney and liver mitochondrial physiology

Rocha-Rodrigues, Silvia; Santos-Alves, Estela; Coxito, Pedro M.; Marques-Aleixo, Ines; Passos, Emanuel; Guimaraes, Joao T.; Martins, Maria J.; et al, 2013. Life Sciences. 329 - 337. 8. 93. 2013. 10.1016/j.lfs.2013.07.004 . Life Sciences

Mitochondrial disruption occurs downstream from ß-adrenergic overactivation by isoproterenol in differentiated, but not undifferentiated H9c2 cardiomyoblasts: differential activation of stress and survival pathways.

Branco AF; Sampaio SF; Wieckowski MR; Sardão VA; Oliveira PJ, 2013. 2013. http://europepmc.org/abstract/med/23958426 . 10.1016/j.biocel.2013.08.006 .

Dioxin-induced acute cardiac mitochondrial oxidative damage and increased activity of ATP-sensitive potassium channels in Wistar rats

Pereira, Susana P.; Pereira, Goncalo C.; Pereira, Claudia V.; Carvalho, Filipa S.; Cordeiro, Marilia H.; Mota, Paula C.; Ramalho-Santos, Joao; Moreno, Antonio J.; Oliveira, Paulo J., 2013. Environmental Pollution. 281 - 290. 180. 2013. 10.1016/j.envpol.2013.05.049 . Environmental Pollution

Acute effects of cocaine, morphine and their combination on bioenergetic function and susceptibility to oxidative stress of rat liver mitochondria

# Cunha-Oliveira, Teresa; Silva, Lisbeth; Silva, Ana Maria; Moreno, António J.; Oliveira, Catarina R.; Santos, Maria S., 2013. Life Sciences. 1157 - 1164. 24-26. 92. 2013. http://dx.doi.org/10.1016/j.lfs.2013.04.016 . 10.1016/j.lfs.2013.04.016 . published Life Sciences

Antenatal manifestations of mitochondrial disorders

Tavares, M.V.; Santos, M.J.; Domingues, A.P.; Pratas, J.; Mendes, C.; Simões, M.; Moura, P.; Diogo, L.; Grazina, M., 2013. Journal of Inherited Metabolic Disease. 805 - 811. 5. 36. 2013. http://www.scopus.com/inward/record.url?eid=2-s2.0-84884350140&partnerID=MN8TOARS . 10.1007/s10545-012-9567-x . Journal of Inherited Metabolic Disease

Edelfosine and perifosine disrupt hepatic mitochondrial oxidative phosphorylation and induce the permeability transition

Burgeiro, Ana; Pereira, Claudia V.; Carvalho, Filipa S.; Pereira, Goncalo C.; Mollinedo, Faustino; Oliveira, Paulo J., 2013. Mitochondrion. 25 - 35. 1. 13. 2013. 10.1016/j.mito.2012.11.003 . Mitochondrion

Citrullinemia stimulation test in the evaluation of the intestinal function | Citrulinemia prueba de estimulación en la evaluación de la función intestinal

Costa, B.P.; Serôdio, M.; Simões, M.; Veríssimo, C.; Sousa, F.C.; Grazina, M., 2013. Nutricion Hospitalaria. 202 - 210. 1. 28. 2013. http://www.scopus.com/inward/record.url?eid=2-s2.0-84872811329&partnerID=MN8TOARS . 10.3305/nh.2013.28.1.6243 . Nutricion Hospitalaria

Gender-dependent metabolic remodeling during heart preservation in cardioplegic celsior and histidine buffer solution

Alves, M.G., 2012. Journal of Cardiovascular Pharmacology. 151 - 157. 2. 59. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84857063384&partnerID=MN8TOARS . 10.1097/FJC.0b013e3182391d17 . Journal of Cardiovascular Pharmacology

The contribution of oxidative stress to drug-induced organ toxicity and its detection in vitro and in vivo

Pereira, C.V., 2012. Expert Opinion on Drug Metabolism and Toxicology. 219 - 237. 2. 8. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84856086570&partnerID=MN8TOARS . 10.1517/17425255.2012.645536 . Expert Opinion on Drug Metabolism and Toxicology

Toxicity evaluation of some traditional African spices on breast cancer cells and isolated rat hepatic mitochondria

Choumessi, A.T., 2012. Food and Chemical Toxicology. 4199 - 4208. 11. 50. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84866522308&partnerID=MN8TOARS . 10.1016/j.fct.2012.08.008 . Food and Chemical Toxicology

Evaluation of respiration with clark type electrode in Isolated mitochondria and permeabilized animal cells

Silva, A.M., 2012. Methods in Molecular Biology. 7 - 24. 810. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-82355193801&partnerID=MN8TOARS . 10.1007/978-1-61779-382-0_2 . Methods in Molecular Biology

Mitochondrionopathy phenotype in doxorubicin-treated wistar rats depends on treatment protocol and is cardiac-specific

Pereira, G.C., 2012. PLoS ONE. 6. 7. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84862661781&partnerID=MN8TOARS . 10.1371/journal.pone.0038867 . PLoS ONE

Role of mitochondria in nonalcoholic fatty liver disease-from origin to propagation

Grattagliano, I., 2012. Clinical Biochemistry. 610 - 618. 9. 45. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84861230299&partnerID=MN8TOARS . 10.1016/j.clinbiochem.2012.03.024 . Clinical Biochemistry

Regulation and protection of mitochondrial physiology by sirtuins

Pereira, C.V., 2012. Mitochondrion. 66 - 76. 1. 12. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84856527254&partnerID=MN8TOARS . 10.1016/j.mito.2011.07.003 . Mitochondrion

Mitochondrial remodeling in cancer metabolism and survival: Potential for new therapies

Barbosa, I.A., 2012. Biochimica et Biophysica Acta - Reviews on Cancer. 238 - 254. 1. 1826. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84860808557&partnerID=MN8TOARS . 10.1016/j.bbcan.2012.04.005 . Biochimica et Biophysica Acta - Reviews on Cancer

Revisiting oxidative stress and mitochondrial dysfunction in the pathogenesis of Parkinson disease - Resemblance to the effect of amphetamine drugs of abuse

Perfeito, R.; * Cunha-Oliveira, T.; Rego, A.C., 2012. Free Radical Biology and Medicine. 1791 - 1806. 9. 53. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84867397192&partnerID=MN8TOARS . 10.1016/j.freeradbiomed.2012.08.569 . Free Radical Biology and Medicine

Exercise as a beneficial adjunct therapy during Doxorubicin treatment-Role of mitochondria in cardioprotection

Ascensão, A., 2012. International Journal of Cardiology. 4 - 10. 1. 156. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84858070585&partnerID=MN8TOARS . 10.1016/j.ijcard.2011.05.060 . International Journal of Cardiology

Minocycline exerts uncoupling and inhibiting effects on mitochondrial respiration through adenine nucleotide translocase inhibition

Cuenca-Lopez, M.D., 2012. Pharmacological Research. 120 - 128. 1. 65. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84855986971&partnerID=MN8TOARS . 10.1016/j.phrs.2011.08.007 . Pharmacological Research

Glutathione redox cycle dysregulation in Huntington’s disease knock-in striatal cells

Ribeiro, Márcio; Rosenstock, Tatiana R.; Cunha-Oliveira, Teresa; Ferreira, Ildete L.; Oliveira, Catarina R.; Rego, A. Cristina, 2012. Free Radical Biology and Medicine. 1857 - 1867. 10. 53. 2012. http://dx.doi.org/10.1016/j.freeradbiomed.2012.09.004 . 10.1016/j.freeradbiomed.2012.09.004 . published Free Radical Biology and Medicine

Disruption of striatal glutamatergic/GABAergic homeostasis following acute methamphetamine in mice

Pereira, Frederico C.; Cunha-Oliveira, Teresa; Viana, Sofia D.; Travassos, Ana S.; Nunes, Sara; Silva, Carlos; Prediger, Rui Daniel; et al, 2012. Neurotoxicology and Teratology. 522 - 529. 5. 34. 2012. http://dx.doi.org/10.1016/j.ntt.2012.07.005 . 10.1016/j.ntt.2012.07.005 . published Neurotoxicology and Teratology

In vitro salicylate does not further impair aging-induced brain mitochondrial dysfunction

Marques-Aleixo, I., 2012. Toxicology. 51 - 59. 1. 302. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84866002199&partnerID=MN8TOARS . 10.1016/j.tox.2012.07.018 . Toxicology

Physical exercise as a possible strategy for brain protection: Evidence from mitochondrial-mediated mechanisms

Marques-Aleixo, I., 2012. Progress in Neurobiology. 149 - 162. 2. 99. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84867896217&partnerID=MN8TOARS . 10.1016/j.pneurobio.2012.08.002 . Progress in Neurobiology

Melatonin modulates autophagy through a redox-mediated action in female Syrian hamster Harderian gland controlling cell types and gland activity

Vega-Naredo, I., 2012. Journal of Pineal Research. 80 - 92. 1. 52. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-83555174326&partnerID=MN8TOARS . 10.1111/j.1600-079X.2011.00922.x . Journal of Pineal Research

Fatty Acid Oxidation and Cardiovascular Risk during Menopause: A Mitochondrial Connection?

Oliveira PJ; Carvalho RA; Portincasa P; Bonfrate L; Sardao VA, 2012. 2012. http://europepmc.org/abstract/med/22496981 . 10.1155/2012/365798 .

Mitochondrial bioenergetics and drug-induced toxicity in a panel of mouse embryonic fibroblasts with mitochondrial DNA single nucleotide polymorphisms

Pereira, C.V., 2012. Toxicology and Applied Pharmacology. 167 - 181. 2. 264. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84866878955&partnerID=MN8TOARS . 10.1016/j.taap.2012.07.030 . Toxicology and Applied Pharmacology

Differentiation-dependent doxorubicin toxicity on h9c2 cardiomyoblasts

Branco, A.F., 2012. Cardiovascular Toxicology. 326 - 340. 4. 12. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84870546889&partnerID=MN8TOARS . 10.1007/s12012-012-9177-8 . Cardiovascular Toxicology

Rational discovery and development of a mitochondria-targeted antioxidant based on cinnamic acid scaffold

Teixeira, J.; Soares, P.; Benfeito, S.; Gaspar, A.; Garrido, J.; Murphy, M.P.; Borges, F., 2012. Free Radical Research. 600 - 611. 5. 46. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84859067775&partnerID=MN8TOARS . 10.3109/10715762.2012.662593 . published Free Radical Research

Endurance training and chronic intermittent hypoxia modulate in vitro salicylate-induced hepatic mitochondrial dysfunction

Ascensão, A., 2012. Mitochondrion. 607 - 616. 6. 12. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84869082628&partnerID=MN8TOARS . 10.1016/j.mito.2012.10.007 . Mitochondrion

Valor da citrulinémia na avaliação da função intestinal na síndroma do intestino curto/ Citrullinemia levels in the evaluation of intestinal function in short bowel syndrome

Beatriz Pinto Costa de Almeida; marco Serôdio; Marta Simões; Carla Veríssimo; Grazina, Manuela; F. Castro Sousa, 2012. Revista Portuguesa de Cirurgia. 9 - 19. 20. II. 2012. https://revista.spcir.com/index.php/spcir/article/view/51 . published Revista Portuguesa de Cirurgia

CYP2C19 (+ or -)*2/(+ or -)*17 Diplotypes: Prognostic impactson patients with acute coronary syndrome

Teixeira, Rogério; Grazina, Manuela; Monteiro, Pedro; Soares, Francisco; Lourenço, Margarida; Pêgo, Guilherme, 2012. World Journal of Cardiovascular Diseases. 260 - 268. 04. 02. 2012. http://dx.doi.org/10.4236/wjcd.2012.24041 . 10.4236/wjcd.2012.24041 . World Journal of Cardiovascular Diseases

Eating disorder symptoms and CYP2D6 variation in cuban healthy females: A report from the Ibero-American network of pharmacogenetics

Peñas-Lledó, E.M.; González, I.; Dorado, P.; Pérez, B.; Calzadilla, L.R.; Alvárez, M.; Naranjo, M.E.G.; Llerena, A., 2012. Current Pharmacogenomics and Personalized Medicine. 288 - 292. 4. 10. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84874831233&partnerID=MN8TOARS . Current Pharmacogenomics and Personalized Medicine

Exposure to dibenzofuran triggers autophagy in lung cells.

Duarte FV; Teodoro JS; Rolo AP; Palmeira CM, 2012. 2012. http://europepmc.org/abstract/med/22173198 . 10.1016/j.toxlet.2011.11.029 .

Pharmacogenetics in Latin American populations: Regulatory aspects, application to herbal medicine, cardiovascular and psychiatric disorders

Rodeiro, I.; Remírez-Figueredo, D.; García-Mesa, M.; Dorado, P.; Llerena, A.; Moya, G.E.; Ferrero, V.; et al, 2012. Drug Metabolism and Drug Interactions. 57 - 60. 1. 27. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84860531136&partnerID=MN8TOARS . 10.1515/dmdi-2012-0006 . Drug Metabolism and Drug Interactions

Development of a HPLC method for the determination of losartan urinary metabolic ratio to be used for the determination of CYP2C9 hydroxylation phenotypes

Dorado, P.; Machín, E.; De Andrés, F.; Naranjo, M.-E.G.; Peñas-Lledó, E.M.; Llerena, A.; Dorado P; et al, 2012. Drug Metabolism and Drug Interactions. 217 - 223. 4. 27. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84877952687&partnerID=MN8TOARS . 10.1515/dmdi-2012-0018 . Drug Metabolism and Drug Interactions

Mitochondrial metabolism in Parkinson's disease impairs quality control autophagy by hampering microtubule-dependent traffic

Arduíno, D.M.; Esteves, A.R.; Cortes, L.; Silva, D.F.; Patel, B.; Grazina, M.; Swerdlow, R.H.; Oliveira, C.R.; Cardoso, S.M., 2012. Human Molecular Genetics. 4680 - 4702. 21. 21. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84867828156&partnerID=MN8TOARS . 10.1093/hmg/dds309 . Human Molecular Genetics

Role of oxidative stress in the pathogenesis of nonalcoholic steatohepatitis.

Rolo AP; Teodoro JS; Palmeira CM, 2012. 2012. http://europepmc.org/abstract/med/22064361 . 10.1016/j.freeradbiomed.2011.10.003 .

Preface

Palmeira, C.M.; Moreno, A.J., 2012. Methods in Molecular Biology. 810. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-82355193804&partnerID=MN8TOARS . Methods in Molecular Biology

SIRT1 is required for AMPK activation and the beneficial effects of resveratrol on mitochondrial function.

Price NL; Gomes AP; Ling AJ; Duarte FV; Martin-Montalvo A; North BJ; Agarwal B; et al, 2012. 2012. http://europepmc.org/abstract/med/22560220 . 10.1016/j.cmet.2012.04.003 .

Nerolidol effects on mitochondrial and cellular energetics.

Ferreira FM; Palmeira CM; Oliveira MM; Santos D; Simões AM; Rocha SM; Coimbra MA; Peixoto F, 2012. 2012. http://europepmc.org/abstract/med/22138475 . 10.1016/j.tiv.2011.11.009 .

Losartan hydroxylation phenotype in an Ecuadorian population: Influence of CYP2C9 genetic polymorphism, habits and gender

Dorado, P.; Beltrán, L.J.; MacHín, E.; Peñas-Lledó, E.M.; Terán, E.; Llerena, A., 2012. Pharmacogenomics. 1711 - 1717. 15. 13. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84870042059&partnerID=MN8TOARS . 10.2217/pgs.12.160 . Pharmacogenomics

Berberine protects against high fat diet-induced dysfunction in muscle mitochondria by inducing SIRT1-dependent mitochondrial biogenesis.

Gomes AP; Duarte FV; Nunes P; Hubbard BP; Teodoro JS; Varela AT; Jones JG; et al, 2012. 2012. http://europepmc.org/abstract/med/22027215 . 10.1016/j.bbadis.2011.10.008 .

Neonatal liver failure due to deoxyguanosine kinase deficiency.

Nobre, S.; Grazina, M.; Silva, F.; Pinto, C.; Gonçalves, I.; Diogo, L., 2012. BMJ case reports. 2012. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84873545510&partnerID=MN8TOARS . 10.1136/bcr.12.2011.5317 . BMJ case reports

Epigenetic engineering to reverse the Parkinson's expression state

Valente, A.X.C.N., 2012. Parkinsonism and Related Disorders. 717 - 721. 6. 18. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84862191970&partnerID=MN8TOARS . 10.1016/j.parkreldis.2012.04.018 . Parkinsonism and Related Disorders

Mitochondrial respiratory chain: Biochemical analysis and criterion for deficiency in diagnosis

Grazina, M.M., 2012. Methods in Molecular Biology. 73 - 91. 837. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84856321622&partnerID=MN8TOARS . 10.1007/978-1-61779-504-6_6 . Methods in Molecular Biology

Antioxidant capacity and toxicological evaluation of Pterospartum tridentatum flower extracts

Ferreira, F.M.; Dinis, L.T.; Azedo, P.; Galhano, C.I.C.; Simões, A.; Cardoso, S.M.; Domingues, M.R.M.; et al, 2012. CYTA - Journal of Food. 92 - 102. 2. 10. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84860268444&partnerID=MN8TOARS . 10.1080/19476337.2011.590233 . CYTA - Journal of Food

Mitochondrial DNA 8993T>G mutation in a child with ornithine transcarbamylase deficiency and leigh syndrome: An unexpected association

Henriques, M.; Diogo, L.; Garcia, P.; Pratas, J.; Simões, M.; Grazina, M., 2012. Journal of Child Neurology. 1059 - 1061. 8. 27. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84864214971&partnerID=MN8TOARS . 10.1177/0883073811431015 . Journal of Child Neurology

Erratum: Gender-dependent metabolic remodeling during heart preservation in cardioplegic celsior and histidine buffer solution (Journal of Cardiovascular Pharmacology (2012) 59 (151-157))

Alves, M.G., 2012. Journal of Cardiovascular Pharmacology. 2. 60. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84865613134&partnerID=MN8TOARS . 10.1097/FJC.0b013e31825cce63 . Journal of Cardiovascular Pharmacology

Exposure to dibenzofuran affects lung mitochondrial function in vitro.

Duarte FV; Simões AM; Teodoro JS; Rolo AP; Palmeira CM, 2011. 2011. http://europepmc.org/abstract/med/21554085 . 10.3109/15376516.2011.576714 .

Re-wiring the circuit: Mitochondria as a pharmacological target in liver disease

Diogo, C.V., 2011. Current Medicinal Chemistry. 5448 - 5465. 35. 18. 2011. http://www.scopus.com/inward/record.url?eid=2-s2.0-82255173714&partnerID=MN8TOARS . 10.2174/092986711798194432 . Current Medicinal Chemistry

Ursodeoxycholic acid treatment of hepatic steatosis: a (13)C NMR metabolic study.

Nunes PM; Jones JG; Rolo AP; Palmeira CM; Carvalho RA, 2011. 2011. http://europepmc.org/abstract/med/21538633 . 10.1002/nbm.1672 .

Mitochondrial tolerance to drugs and toxic agents in ageing and disease

Suski, J., 2011. Current Drug Targets. 827 - 849. 6. 12. 2011. http://www.scopus.com/inward/record.url?eid=2-s2.0-79955592779&partnerID=MN8TOARS . 10.2174/138945011795529029 . Current Drug Targets

Assessment of the toxicity of silver nanoparticles in vitro: a mitochondrial perspective.

Teodoro JS; Simões AM; Duarte FV; Rolo AP; Murdoch RC; Hussain SM; Palmeira CM, 2011. 2011. http://europepmc.org/abstract/med/21232593 . 10.1016/j.tiv.2011.01.004 .

Mitochondria in chronic liver disease

Grattagliano, I., 2011. Current Drug Targets. 879 - 893. 6. 12. 2011. http://www.scopus.com/inward/record.url?eid=2-s2.0-79955606583&partnerID=MN8TOARS . 10.2174/138945011795528877 . Current Drug Targets

Differential sex, morphotype and tissue accumulation of mercury in the crab Carcinus maenas

Costa, S.; Viegas, I.; Pereira, E.; Duarte, A.C.; Palmeira, C.M.; Pardal, M.A., 2011. Water, Air, and Soil Pollution. 65 - 75. 1-4. 222. 2011. http://www.scopus.com/inward/record.url?eid=2-s2.0-80755188894&partnerID=MN8TOARS . 10.1007/s11270-011-0809-6 . Water, Air, and Soil Pollution

Mitochondria as a drug target in health and disease

Oliveira, P.J., 2011. Current Drug Targets. 6. 12. 2011. http://www.scopus.com/inward/record.url?eid=2-s2.0-79955623985&partnerID=MN8TOARS . 10.2174/138945011795528912 . Current Drug Targets

Mitochondria as a target for exercise-induced cardioprotection

Ascensão, A., 2011. Current Drug Targets. 860 - 871. 6. 12. 2011. http://www.scopus.com/inward/record.url?eid=2-s2.0-79955608557&partnerID=MN8TOARS . 10.2174/138945011795529001 . Current Drug Targets

Metabolic remodeling during H9c2 myoblast differentiation: Relevance for in vitro toxicity studies

Pereira, S.L., 2011. Cardiovascular Toxicology. 180 - 190. 2. 11. 2011. http://www.scopus.com/inward/record.url?eid=2-s2.0-79958056642&partnerID=MN8TOARS . 10.1007/s12012-011-9112-4 . Cardiovascular Toxicology

Substrate selection in hearts subjected to ischemia/reperfusion: Role of cardioplegic solutions and gender

Alves, M.G., 2011. NMR in Biomedicine. 1029 - 1037. 9. 24. 2011. http://www.scopus.com/inward/record.url?eid=2-s2.0-80054064346&partnerID=MN8TOARS . 10.1002/nbm.1640 . NMR in Biomedicine

Hepatic FXR: key regulator of whole-body energy metabolism.

Teodoro JS; Rolo AP; Palmeira CM, 2011. 2011. http://europepmc.org/abstract/med/21862343 . 10.1016/j.tem.2011.07.002 .

Differential effects of p,p'-DDE on testis and liver mitochondria:Implications for reproductive toxicology

Mota, P.C., 2011. Reproductive Toxicology. 80 - 85. 1. 31. 2011. http://www.scopus.com/inward/record.url?eid=2-s2.0-79551613557&partnerID=MN8TOARS . 10.1016/j.reprotox.2010.09.010 . Reproductive Toxicology

Sodium hydrosulfide improves the protective potential of the cardioplegic histidine buffer solution

Alves, M.G., 2011. European Journal of Pharmacology. 60 - 67. 1. 654. 2011. http://www.scopus.com/inward/record.url?eid=2-s2.0-78951491593&partnerID=MN8TOARS . 10.1016/j.ejphar.2010.12.010 . European Journal of Pharmacology

Mitochondria from distinct tissues are differently affected by 17ß-estradiol and tamoxifen

Moreira, P.I., 2011. Journal of Steroid Biochemistry and Molecular Biology. 8 - 16. 1-2. 123. 2011. http://www.scopus.com/inward/record.url?eid=2-s2.0-78650578395&partnerID=MN8TOARS . 10.1016/j.jsbmb.2010.09.004 . Journal of Steroid Biochemistry and Molecular Biology

Drug-induced cardiac mitochondrial toxicity and protection: From doxorubicin to carvedilol

Pereira, G.C., 2011. Current Pharmaceutical Design. 2113 - 2129. 20. 17. 2011. http://www.scopus.com/inward/record.url?eid=2-s2.0-80052226370&partnerID=MN8TOARS . 10.2174/138161211796904812 . Current Pharmaceutical Design

Nimesulide interaction with membrane model systems: Are membrane physical effects involved in nimesulide mitochondrial toxicity?

Monteiro, J.P., 2011. Toxicology in Vitro. 1215 - 1223. 6. 25. 2011. http://www.scopus.com/inward/record.url?eid=2-s2.0-79960964709&partnerID=MN8TOARS . 10.1016/j.tiv.2011.05.014 . Toxicology in Vitro

Anti-apoptotic protection afforded by cardioplegic celsior and histidine buffer solutions to hearts subjected to ischemia and ischemia/reperfusion

Alves, M.G., 2011. Journal of Cellular Biochemistry. 3872 - 3881. 12. 112. 2011. http://www.scopus.com/inward/record.url?eid=2-s2.0-80055000219&partnerID=MN8TOARS . 10.1002/jcb.23320 . Journal of Cellular Biochemistry

Acute exercise protects against calcium-induced cardiac mitochondrial permeability transition pore opening in doxorubicin-treated rats

Ascensão, A., 2011. Clinical Science. 37 - 49. 1. 120. 2011. http://www.scopus.com/inward/record.url?eid=2-s2.0-78650871083&partnerID=MN8TOARS . 10.1042/CS20100254 . Clinical Science

Regulation of mitochondrial biogenesis in metabolic syndrome.

Rolo AP; Gomes AP; Palmeira CM, 2011. 2011. http://europepmc.org/abstract/med/21269264 . 10.2174/138945011795529056 .

Lipophilic caffeic and ferulic acid derivatives presenting cytotoxicity against human breast cancer cells

Serafim, T.L., 2011. Chemical Research in Toxicology. 763 - 774. 5. 24. 2011. http://www.scopus.com/inward/record.url?eid=2-s2.0-79956157475&partnerID=MN8TOARS . 10.1021/tx200126r . Chemical Research in Toxicology

Isoproterenol cytotoxicity is dependent on the differentiation state of the cardiomyoblast H9c2 cell line

Branco, A.F., 2011. Cardiovascular Toxicology. 191 - 203. 3. 11. 2011. http://www.scopus.com/inward/record.url?eid=2-s2.0-80054914028&partnerID=MN8TOARS . 10.1007/s12012-011-9111-5 . Cardiovascular Toxicology

Berberine as a promising safe anti-cancer agent - is there a role for mitochondria?

Diogo, C.V., 2011. Current Drug Targets. 850 - 859. 6. 12. 2011. http://www.scopus.com/inward/record.url?eid=2-s2.0-79955619830&partnerID=MN8TOARS . 10.2174/138945011795528930 . Current Drug Targets

Involvement of mitochondrial and B-RAF/ERK signaling pathways in berberine-induced apoptosis in human melanoma cells

Burgeiro, A., 2011. Anti-Cancer Drugs. 507 - 518. 6. 22. 2011. http://www.scopus.com/inward/record.url?eid=2-s2.0-79958289658&partnerID=MN8TOARS . 10.1097/CAD.0b013e32834438f6 . Anti-Cancer Drugs

Interaction of carbonylcyanide p-trifluoromethoxyphenylhydrazone (FCCP) with lipid membrane systems: A biophysical approach with relevance to mitochondrial uncoupling

Monteiro, J.P., 2011. Journal of Bioenergetics and Biomembranes. 287 - 298. 3. 43. 2011. http://www.scopus.com/inward/record.url?eid=2-s2.0-79959768623&partnerID=MN8TOARS . 10.1007/s10863-011-9359-2 . Journal of Bioenergetics and Biomembranes

Bioenergetic dysfunction in Huntington's disease human cybrids

Ferreira, I. Luisa; * Cunha-Oliveira, Teresa; Nascimento, Maria V.; Ribeiro, Márcio; Proença, M. Teresa; Januário, Cristina; Oliveira, Catarina R.; Rego, A. Cristina, 2011. Experimental Neurology. 127 - 134. 1. 231. 2011. http://dx.doi.org/10.1016/j.expneurol.2011.05.024 . 10.1016/j.expneurol.2011.05.024 . published Experimental Neurology

Erratum: Isoproterenol cytotoxicity is dependent on the differentiation state of the cardiomyoblast H9c2 cell line (Cardiovascular Toxicology DOI: 10.1007/s12012-011-9111-5)

Branco, A.F., 2011. Cardiovascular Toxicology. 3. 11. 2011. http://www.scopus.com/inward/record.url?eid=2-s2.0-80054890288&partnerID=MN8TOARS . 10.1007/s12012-011-9131-1 . Cardiovascular Toxicology

Fatty liver and ischemia/reperfusion: are there drugs able to mitigate injury?

Varela AT; Rolo AP; Palmeira CM, 2011. 2011. http://europepmc.org/abstract/med/22050747 . 10.2174/092986711797535164 .

Endurance training reverts heart mitochondrial dysfunction, permeability transition and apoptotic signaling in long-term severe hyperglycemia

Lumini-Oliveira, J., 2011. Mitochondrion. 54 - 63. 1. 11. 2011. http://www.scopus.com/inward/record.url?eid=2-s2.0-78650035561&partnerID=MN8TOARS . 10.1016/j.mito.2010.07.005 . Mitochondrion

Dimethylaminopyridine derivatives of lupane triterpenoids are potent disruptors of mitochondrial structure and function

Holy, J., 2010. Bioorganic and Medicinal Chemistry. 6080 - 6088. 16. 18. 2010. http://www.scopus.com/inward/record.url?eid=2-s2.0-77955472585&partnerID=MN8TOARS . 10.1016/j.bmc.2010.06.075 . Bioorganic and Medicinal Chemistry

Mg2+-doped poly(epsilon-caprolactone)/siloxane biohybrids

Teixeira, J. C. S.; Fernandes, M.; Bermudez, V. de Zea; Barbosa, P. C.; Rodrigues, L. C.; Silva, M. M.; Smith, M. J., 2010. Electrochimica Acta. 1328 - 1332. 4. 55. 2010. 10.1016/j.electacta.2009.06.024 . published Electrochimica Acta

Biapigenin modulates the activity of the adenine nucleotide translocator in isolated rat brain mitochondria

Silva, B.A., 2010. Neurotoxicity Research. 75 - 90. 1. 17. 2010. http://www.scopus.com/inward/record.url?eid=2-s2.0-77449110345&partnerID=MN8TOARS . 10.1007/s12640-009-9082-5 . Neurotoxicity Research

Erratum: Nitrogen compounds prevent H9c2 myoblast oxidative stress-induced mitochondrial dysfunction and cell death (Cardiovascular Toxicology (2010) 10 (51-65) DOI:10.1007/s12012-010-9062-2)

Silva, J.P., 2010. Cardiovascular Toxicology. 2. 10. 2010. http://www.scopus.com/inward/record.url?eid=2-s2.0-77956395509&partnerID=MN8TOARS . 10.1007/s12012-010-9067-x . Cardiovascular Toxicology

Long-term hyperglycaemia decreases gastrocnemius susceptibility to permeability transition

Lumini-Oliveira, J., 2010. European Journal of Clinical Investigation. 319 - 329. 4. 40. 2010. http://www.scopus.com/inward/record.url?eid=2-s2.0-77949664613&partnerID=MN8TOARS . 10.1111/j.1365-2362.2010.02267.x . European Journal of Clinical Investigation

Sub-chronic administration of doxorubicin to Wistar rats results in oxidative stress and unaltered apoptotic signaling in the lung

Machado, N.G., 2010. Chemico-Biological Interactions. 478 - 486. 3. 188. 2010. http://www.scopus.com/inward/record.url?eid=2-s2.0-78149466319&partnerID=MN8TOARS . 10.1016/j.cbi.2010.09.027 . Chemico-Biological Interactions

Nitrogen compounds prevent h9c2 myoblast oxidative stress-induced mitochondrial dysfunction and cell death.

Silva JP; Sardão VA; Coutinho OP; Oliveira PJ; Olveira PJ, 2010. 2010. http://europepmc.org/abstract/med/20119745 . 10.1007/s12012-010-9062-2 .

Electrochemical oxidation of sanguinarine and of its oxidation products at a glassy carbon electrode - relevance to intracellular effects

Diculescu, V.C., 2010. Electroanalysis. 113 - 120. 1. 22. 2010. http://www.scopus.com/inward/record.url?eid=2-s2.0-72649099240&partnerID=MN8TOARS . 10.1002/elan.200900367 . Electroanalysis

Exposure to 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin and tetraethyl lead affects lung mitochondria bioenergetics.

Simões AM; Duarte FV; Teodoro JS; Rolo AP; Palmeira CM, 2010. 2010. http://europepmc.org/abstract/med/20158383 . 10.3109/15376510903527916 .

Neurotoxicity of heroin-cocaine combinations in rat cortical neurons

Cunha-Oliveira, T.; Rego, A.C.; Garrido, J.; Borges, F.; Macedo, T.; Oliveira, C.R., 2010. Toxicology. 11 - 17. 1. 276. 2010. http://dx.doi.org/10.1016/j.tox.2010.06.009 . 10.1016/j.tox.2010.06.009 . published Toxicology

Regulation of the mPTP by SIRT3-mediated deacetylation of CypD at lysine 166 suppresses age-related cardiac hypertrophy

Hafner, A.V.; Dai, J.; Gomes, A.P.; Xiao, C.-Y.; Palmeira, K.C.M.; Rosenzweig, A.; Sinclair, D.A.; et al, 2010. Aging. 914 - 923. 12. 2. 2010. http://www.scopus.com/inward/record.url?eid=2-s2.0-79952266729&partnerID=MN8TOARS . Aging

Metabolic remodeling associated with subchronic doxorubicin cardiomyopathy.

Carvalho RA; Sousa RP; Cadete VJ; Lopaschuk GD; Palmeira CM; Bjork JA; Wallace KB, 2010. 2010. http://europepmc.org/abstract/med/20132857 . 10.1016/j.tox.2010.01.019 .

Value of Brain Magnetic Resonance Imaging in Mitochondrial Respiratory Chain Disorders

Diogo, L.; Cordeiro, M.; Garcia, P.; Fineza, I.; Moura, C.; Oliveira, C.R.; Veiga, M.; Garcia, T.; Grazina, M., 2010. Pediatric Neurology. 196 - 200. 3. 42. 2010. http://www.scopus.com/inward/record.url?eid=2-s2.0-76249116575&partnerID=MN8TOARS . 10.1016/j.pediatrneurol.2009.09.010 . Pediatric Neurology

Indirubin-3'-oxime prevents hepatic I/R damage by inhibiting GSK-3beta and mitochondrial permeability transition.

Varela AT; Simões AM; Teodoro JS; Duarte FV; Gomes AP; Palmeira CM; Rolo AP, 2010. 2010. http://europepmc.org/abstract/med/20433952 . 10.1016/j.mito.2010.04.006 .

Mitochondrial-dependent apoptosis in Huntington's disease human cybrids

Ferreira, I.L.; Nascimento, M.V.; Ribeiro, M.; Almeida, S.; Cardoso, S.M.; Grazina, M.; Pratas, J.; et al, 2010. Experimental Neurology. 243 - 255. 2. 222. 2010. http://www.scopus.com/inward/record.url?eid=2-s2.0-77549084450&partnerID=MN8TOARS . 10.1016/j.expneurol.2010.01.002 . Experimental Neurology

Determinação da citrulinémia após cirurgia Bariátrica ¿ Análise Preliminar / Determination of citrullinemia after bariatric surgery

Costa, BP; Serôdio, M.; Rodrigues, A; Simões, Marta; Veríssimo, C.; Grazina, Manuela; Sousa, FC, 2010. APNEP – Associação Portuguesa de Nutrição Entérica e Parentérica. 1. IV. 2010. published APNEP – Associação Portuguesa de Nutrição Entérica e Parentérica

Morphological alterations induced by doxorubicin on H9c2 myoblasts: Nuclear, mitochondrial, and cytoskeletal targets

Sardão, V.A., 2009. Cell Biology and Toxicology. 227 - 243. 3. 25. 2009. http://www.scopus.com/inward/record.url?eid=2-s2.0-67349167673&partnerID=MN8TOARS . 10.1007/s10565-008-9070-1 . Cell Biology and Toxicology

Mitochondrial preservation in celsior versus histidine buffer solution during cardiac Ischemia and reperfusion

Alves, M.G., 2009. Cardiovascular Toxicology. 185 - 193. 4. 9. 2009. http://www.scopus.com/inward/record.url?eid=2-s2.0-71949090655&partnerID=MN8TOARS . 10.1007/s12012-009-9052-4 . Cardiovascular Toxicology

Investigating drug-induced mitochondrial toxicity: A biosensor to increase drug safety?

Pereira, C.V., 2009. Current Drug Safety. 34 - 54. 1. 4. 2009. http://www.scopus.com/inward/record.url?eid=2-s2.0-63249131066&partnerID=MN8TOARS . 10.2174/157488609787354440 . Current Drug Safety

Doxorubicin-induced mitochondrial dysfunction is secondary to nuclear p53 activation in H9c2 cardiomyoblasts

Sardão, V.A., 2009. Cancer Chemotherapy and Pharmacology. 811 - 827. 4. 64. 2009. http://www.scopus.com/inward/record.url?eid=2-s2.0-68149169047&partnerID=MN8TOARS . 10.1007/s00280-009-0932-x . Cancer Chemotherapy and Pharmacology

Testicular mitochondrial alterations in untreated streptozotocin-induced diabetic rats

Amaral, S., 2009. Mitochondrion. 41 - 50. 1. 9. 2009. http://www.scopus.com/inward/record.url?eid=2-s2.0-60249101037&partnerID=MN8TOARS . 10.1016/j.mito.2008.11.005 . Mitochondrion

Mitochondrial bioenergetics of testicular cells from the domestic cat (Felis catus)-A model for endangered species

Mota, P., 2009. Reproductive Toxicology. 111 - 116. 2. 27. 2009. http://www.scopus.com/inward/record.url?eid=2-s2.0-62549148154&partnerID=MN8TOARS . 10.1016/j.reprotox.2009.01.008 . Reproductive Toxicology

Can drug safety be predicted and animal experiments reduced by using isolated mitochondrial fractions?

Pereira, S.P.; Pereira SP; Pereira GC; Moreno AJ; Oliveira PJ, 2009. ATLA Alternatives to Laboratory Animals. 355 - 365. 4. 37. 2009. http://www.scopus.com/inward/record.url?eid=2-s2.0-70449604749&partnerID=MN8TOARS . ATLA Alternatives to Laboratory Animals

Doxorubicin: The good, the bad and the ugly effect

Carvalho, C., 2009. Current Medicinal Chemistry. 3267 - 3285. 25. 16. 2009. http://www.scopus.com/inward/record.url?eid=2-s2.0-70450215499&partnerID=MN8TOARS . 10.2174/092986709788803312 . Current Medicinal Chemistry

Parabens in male infertility-Is there a mitochondrial connection?

Tavares, R.S., 2009. Reproductive Toxicology. 1 - 7. 1. 27. 2009. http://www.scopus.com/inward/record.url?eid=2-s2.0-58749116602&partnerID=MN8TOARS . 10.1016/j.reprotox.2008.10.002 . Reproductive Toxicology

Mitochondrial toxicity of the phyotochemicals daphnetoxin and daphnoretin - Relevance for possible anti-cancer application

Diogo, C.V., 2009. Toxicology in Vitro. 772 - 779. 5. 23. 2009. http://www.scopus.com/inward/record.url?eid=2-s2.0-67649401716&partnerID=MN8TOARS . 10.1016/j.tiv.2009.04.002 . Toxicology in Vitro

Endurance training improves gastrocnemius mitochondrial function despite increased susceptibility to permeability transition

Lumini-Oliveira, J., 2009. Mitochondrion. 454 - 462. 6. 9. 2009. http://www.scopus.com/inward/record.url?eid=2-s2.0-70449133441&partnerID=MN8TOARS . 10.1016/j.mito.2009.08.005 . Mitochondrion

Electrochemical oxidation of berberine and of its oxidation products at a glassy carbon electrode

Diculescu, V.C., 2009. Electroanalysis. 1027 - 1034. 9. 21. 2009. http://www.scopus.com/inward/record.url?eid=2-s2.0-66649083195&partnerID=MN8TOARS . 10.1002/elan.200804516 . Electroanalysis

Biosensor plates detect mitochondrial physiological regulators and mutations in vivo.

Rolo AP; Palmeira CM; Cortopassi GA, 2009. 2009. http://europepmc.org/abstract/med/18950600 . 10.1016/j.ab.2008.10.002 .

BDNF regulates BIM expression levels in 3-nitropropionic acid-treated cortical neurons

Almeida, S.; Laço, M.; Cunha-Oliveira, T.; Oliveira, C.R.; Rego, A.C., 2009. Neurobiology of Disease. 448 - 456. 3. 35. 2009. http://dx.doi.org/10.1016/j.nbd.2009.06.006 . 10.1016/j.nbd.2009.06.006 . published Neurobiology of Disease

Prevention of I/R injury in fatty livers by ischemic preconditioning is associated with increased mitochondrial tolerance: the key role of ATPsynthase and mitochondrial permeability transition.

Rolo AP; Teodoro JS; Peralta C; Rosello-Catafau J; Palmeira CM, 2009. 2009. http://europepmc.org/abstract/med/19619169 . 10.1111/j.1432-2277.2009.00916.x .

The brain-heart connection in mitochondrial respiratory chain diseases.

Cordeiro M; Scaglia F; Lopes Da Silva S; Garcia P; Grazina M; Moura C; Diogol L; et al, 2009. Neuroradiology Journal. 558 - 563. 5. 22. 2009. http://europepmc.org/abstract/med/24209401 . 10.1177/197140090902200508 . Neuroradiology Journal

Dysregulation of CREB Activation and Histone Acetylation in 3-Nitropropionic Acid-Treated Cortical Neurons: Prevention by BDNF and NGF

Almeida, Sandra; Cunha-Oliveira, Teresa; Laço, Mário; Oliveira, Catarina R.; Rego, A. Cristina, 2009. Neurotoxicity Research. 399 - 405. 4. 17. 2009. http://dx.doi.org/10.1007/s12640-009-9116-z . 10.1007/s12640-009-9116-z . published Neurotoxicity Research

Pediatric Mitochondrial Respiratory Chain Disorders in the Centro Region of Portugal

Diogo, L.; Grazina, M.; Garcia, P.; Rebelo, O.; Veiga, M.A.; Cuevas, J.; Vilarinho, L.; de Almeida, I.T.; Oliveira, C.R., 2009. Pediatric Neurology. 351 - 356. 5. 40. 2009. http://www.scopus.com/inward/record.url?eid=2-s2.0-64549161480&partnerID=MN8TOARS . 10.1016/j.pediatrneurol.2008.11.012 . Pediatric Neurology

Mitochondrial involvement in cardiac apoptosis during ischemia and reperfusion: can we close the box?

Machado NG; Alves MG; Carvalho RA; Oliveira PJ, 2009. 2009. http://europepmc.org/abstract/med/19855945 . 10.1007/s12012-009-9055-1 .

Indirubin-3'-oxime impairs mitochondrial oxidative phosphorylation and prevents mitochondrial permeability transition induction.

Varela AT; Gomes AP; Simões AM; Teodoro JS; Duarte FV; Rolo AP; Palmeira CM, 2008. 2008. http://europepmc.org/abstract/med/18786556 . 10.1016/j.taap.2008.08.005 .

Estimating gluconeogenesis by NMR isotopomer distribution analysis of [13C]bicarbonate and [1-13C]lactate.

Alves TC; Nunes PM; Palmeira CM; Jones JG; Carvalho RA, 2008. 2008. http://europepmc.org/abstract/med/17683055 . 10.1002/nbm.1195 .

Quercetin, kaempferol and biapigenin from hypericum perforatum are neuroprotective against excitotoxic insults

Silva, B., 2008. Neurotoxicity Research. 265 - 279. 3-4. 13. 2008. http://www.scopus.com/inward/record.url?eid=2-s2.0-55249095521&partnerID=MN8TOARS . 10.1007/BF03033510 . Neurotoxicity Research

Doxorubicin increases the susceptibility of brain mitochondria to Ca2+-induced permeability transition and oxidative damage

Cardoso, S., 2008. Free Radical Biology and Medicine. 1395 - 1402. 10. 45. 2008. http://www.scopus.com/inward/record.url?eid=2-s2.0-54349099428&partnerID=MN8TOARS . 10.1016/j.freeradbiomed.2008.08.008 . Free Radical Biology and Medicine

Evaluation of olive oil mill wastewater toxicity on the mitochondrial bioenergetics after treatment with Candida oleophila

Peixoto, F.; Martins, F.; Amaral, C.; Gomes-Laranjo, J.; Almeida, J.; Palmeira, C.M., 2008. Ecotoxicology and Environmental Safety. 266 - 275. 2. 70. 2008. http://www.scopus.com/inward/record.url?eid=2-s2.0-42049108014&partnerID=MN8TOARS . 10.1016/j.ecoenv.2007.11.003 . Ecotoxicology and Environmental Safety

Mitochondria a key role in microcystin-LR kidney intoxication.

La-Salete R; Oliveira MM; Palmeira CA; Almeida J; Peixoto FP, 2008. 2008. http://europepmc.org/abstract/med/17461434 . 10.1002/jat.1251 .

Differential alterations in mitochondrial function induced by a choline-deficient diet: understanding fatty liver disease progression.

Teodoro JS; Rolo AP; Duarte FV; Simões AM; Palmeira CM, 2008. 2008. http://europepmc.org/abstract/med/18765303 . 10.1016/j.mito.2008.07.008 .

Drug-induced mitochondrial dysfunction in cardiac and skeletal muscle injury.

Sardão VA; Pereira SL; Oliveira PJ, 2008. 2008. http://europepmc.org/abstract/med/18324876 . 10.1517/14740338.7.2.129 .

Disruption of hepatic mitochondrial bioenergetics is not a primary mechanism for the toxicity of methoprene - relevance for toxicological assessment.

Monteiro JP; Oliveira PJ; Moreno AJ; Jurado AS, 2008. 2008. http://europepmc.org/abstract/med/18511104 . 10.1016/j.chemosphere.2008.04.024 .

Inhibition of the adenine nucleotide translocator by N-acetyl perfluorooctane sulfonamides in vitro

O'Brien, T.M., 2008. Toxicology and Applied Pharmacology. 184 - 195. 2. 227. 2008. http://www.scopus.com/inward/record.url?eid=2-s2.0-38949127988&partnerID=MN8TOARS . 10.1016/j.taap.2007.10.016 . Toxicology and Applied Pharmacology

Mechanisms of berberine (Natural Yellow 18) - Induced mitochondrial dysfunction: Interaction with the adenine nucleotide translocator

Pereira, C.V., 2008. Toxicological Sciences. 408 - 417. 2. 105. 2008. http://www.scopus.com/inward/record.url?eid=2-s2.0-51849122083&partnerID=MN8TOARS . 10.1093/toxsci/kfn131 . Toxicological Sciences

Sanguinarine cytotoxicity on mouse melanoma K1735-M2 cells-Nuclear vs. mitochondrial effects

Serafim, T.L., 2008. Biochemical Pharmacology. 1459 - 1475. 11. 76. 2008. http://www.scopus.com/inward/record.url?eid=2-s2.0-55949119796&partnerID=MN8TOARS . 10.1016/j.bcp.2008.07.013 . Biochemical Pharmacology

Testicular aging involves mitochondrial dysfunction as well as an increase in UCP2 levels and proton leak

Amaral, S., 2008. FEBS Letters. 4191 - 4196. 30. 582. 2008. http://www.scopus.com/inward/record.url?eid=2-s2.0-57649108974&partnerID=MN8TOARS . 10.1016/j.febslet.2008.11.020 . FEBS Letters

Beneficial effects of exercise on muscle mitochondrial function in diabetes mellitus

Lumini, J.A., 2008. Sports Medicine. 735 - 750. 9. 38. 2008. http://www.scopus.com/inward/record.url?eid=2-s2.0-49949103399&partnerID=MN8TOARS . 10.2165/00007256-200838090-00003 . Sports Medicine

Complex formation between heptakis(2,6-di-O-methyl)-ß-cyclodextrin and cyclopentadienyl molybdenum(II) dicarbonyl complexes: Structural studies and cytotoxicity evaluations

Pereira, C.C.L., 2008. Organometallics. 4948 - 4956. 19. 27. 2008. http://www.scopus.com/inward/record.url?eid=2-s2.0-54249115357&partnerID=MN8TOARS . 10.1021/om800413w . Organometallics

Diabetes and the impairment of reproductive function: Possible role of mitochondria and reactive oxygen species

Amaral, S., 2008. Current Diabetes Reviews. 46 - 54. 1. 4. 2008. http://www.scopus.com/inward/record.url?eid=2-s2.0-38949101210&partnerID=MN8TOARS . 10.2174/157339908783502398 . Current Diabetes Reviews

Different concentrations of berberine result in distinct cellular localization patterns and cell cycle effects in a melanoma cell line

Serafim, T.L., 2008. Cancer Chemotherapy and Pharmacology. 1007 - 1018. 6. 61. 2008. http://www.scopus.com/inward/record.url?eid=2-s2.0-41049098849&partnerID=MN8TOARS . 10.1007/s00280-007-0558-9 . Cancer Chemotherapy and Pharmacology

Cellular and molecular mechanisms involved in the neurotoxicity of opioid and psychostimulant drugs

Cunha-Oliveira, T.; Rego, A.C.; Oliveira, C.R.; Cunha-Oliveira, Teresa; Rego, Ana Cristina; Oliveira, Catarina R., 2008. Brain Research Reviews. 192 - 208. 1. 58. 2008. http://dx.doi.org/10.1016/j.brainresrev.2008.03.002 . 10.1016/j.brainresrev.2008.03.002 . Brain Research Reviews

Hyperglycemia decreases mitochondrial function: the regulatory role of mitochondrial biogenesis.

Palmeira CM; Rolo AP; Berthiaume J; Bjork JA; Wallace KB, 2007. 2007. http://europepmc.org/abstract/med/17761203 . 10.1016/j.taap.2007.07.015 .

Adaptation to oxidative stress in the chronic effects of cocaine and amphetamine

Cunha-Oliveira, T; Rego, AC; Macedo, T; Oliveira, CR, 2007. Free Radical Research. S22 - S22. 41. 2007. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000252296300068&KeyUID=WOS:000252296300068 . Free Radical Research

Atypical presentation of Leber's hereditary optic neuropathy associated to mtDNA 11778G>A point mutation-A case report

Grazina, M.M.; Diogo, L.M.; Garcia, P.C.; Silva, E.D.; Garcia, T.D.; Robalo, C.B.; Oliveira, C.R., 2007. European Journal of Paediatric Neurology. 115 - 118. 2. 11. 2007. http://www.scopus.com/inward/record.url?eid=2-s2.0-33847234224&partnerID=MN8TOARS . 10.1016/j.ejpn.2006.11.015 . European Journal of Paediatric Neurology

Response [2]

Oliveira, P.J., 2007. Journal of Biochemical and Molecular Toxicology. 6. 21. 2007. http://www.scopus.com/inward/record.url?eid=2-s2.0-36749085079&partnerID=MN8TOARS . 10:1002/jbt . Journal of Biochemical and Molecular Toxicology

Mitochondrially targeted effects of berberine [Natural Yellow 18, 5,6-dihydro-9,10-dimethoxybenzo(g)-1,3-benzodioxolo(5,6-a) quinolizinium] on K1735-M2 mouse melanoma cells: Comparison with direct effects on isolated mitochondrial fractions

Pereira, G.C., 2007. Journal of Pharmacology and Experimental Therapeutics. 636 - 649. 2. 323. 2007. http://www.scopus.com/inward/record.url?eid=2-s2.0-35548974344&partnerID=MN8TOARS . 10.1124/jpet.107.128017 . Journal of Pharmacology and Experimental Therapeutics

Unaltered hepatic oxidative phosphorylation and mitochondrial permeability transition in Wistar rats treated with nimesulide: Relevance for nimesulide toxicity characterization

Moreno, A.J., 2007. Journal of Biochemical and Molecular Toxicology. 53 - 61. 2. 21. 2007. http://www.scopus.com/inward/record.url?eid=2-s2.0-34247399590&partnerID=MN8TOARS . 10.1002/jbt.20159 . Journal of Biochemical and Molecular Toxicology

Vital imaging of H9c2 myoblasts exposed to tert-butylhydroperoxide - Characterization of morphological features of cell death

Sardão, V.A., 2007. BMC Cell Biology. 8. 2007. http://www.scopus.com/inward/record.url?eid=2-s2.0-33947598915&partnerID=MN8TOARS . 10.1186/1471-2121-8-11 . BMC Cell Biology

Vitamin E prevents hypobaric hypoxia-induced mitochondrial dysfunction in skeletal muscle

Magalhães, J., 2007. Clinical Science. 459 - 466. 11-12. 113. 2007. http://www.scopus.com/inward/record.url?eid=2-s2.0-36849067904&partnerID=MN8TOARS . 10.1042/CS20070075 . Clinical Science

Inhibition of mitochondrial bioenergetics by carbaryl is only evident for higher concentrations - Relevance for carbaryl toxicity mechanisms

Moreno, A.J.M., 2007. Chemosphere. 404 - 411. 3. 66. 2007. http://www.scopus.com/inward/record.url?eid=2-s2.0-33751232011&partnerID=MN8TOARS . 10.1016/j.chemosphere.2006.06.030 . Chemosphere

Mitochondria as targets for neuronal protection against excitotoxicity: A role for phenolic compounds?

Silva, B.A., 2007. Central Nervous System Agents in Medicinal Chemistry. 205 - 222. 3. 7. 2007. http://www.scopus.com/inward/record.url?eid=2-s2.0-34548408654&partnerID=MN8TOARS . 10.2174/187152407781669152 . Central Nervous System Agents in Medicinal Chemistry

Street heroin induces mitochondrial dysfunction and apoptosis in rat cortical neurons

Cunha-Oliveira, T.; Rego, A.C.; Garrido, J.; Borges, F.; Macedo, T.; Oliveira, C.R., 2007. Journal of Neurochemistry. 543 - 554. 2. 101. 2007. http://dx.doi.org/10.1111/j.1471-4159.2006.04406.x . 10.1111/j.1471-4159.2006.04406.x . Journal of Neurochemistry

Decreased ANT content in Zucker fatty rats: relevance for altered hepatic mitochondrial bioenergetics in steatosis.

Teodoro J; Rolo AP; Oliveira PJ; Palmeira CM, 2006. 2006. http://europepmc.org/abstract/med/16554051 . 10.1016/j.febslet.2006.02.078 .

Brief report: High frequency of biochemical markers for mitochondrial dysfunction in autism: No association with the mitochondrial aspartate/glutamate carrier SLC25A12 gene

Correia, C.; Coutinho, A.M.; Diogo, L.; Grazina, M.; Marques, C.; Miguel, T.; Ataíde, A.; et al, 2006. Journal of Autism and Developmental Disorders. 1137 - 1140. 8. 36. 2006. http://www.scopus.com/inward/record.url?eid=2-s2.0-33845912666&partnerID=MN8TOARS . 10.1007/s10803-006-0138-6 . Journal of Autism and Developmental Disorders

Genetic basis of Alzheimer's dementia: Role of mtDNA mutations

Grazina, M.; Pratas, J.; Silva, F.; Oliveira, S.; Santana, I.; Oliveira, C., 2006. Genes, Brain and Behavior. 92 - 107. SUPPL. 2. 5. 2006. http://www.scopus.com/inward/record.url?eid=2-s2.0-33646236099&partnerID=MN8TOARS . 10.1111/j.1601-183X.2006.00225.x . Genes, Brain and Behavior

Diabetes and mitochondrial function: role of hyperglycemia and oxidative stress.

Rolo AP; Palmeira CM, 2006. 2006. http://europepmc.org/abstract/med/16490224 . 10.1016/j.taap.2006.01.003 .

Efeito crónico da heroína e do peróxido de hidrogénio em células PC12

Cunha-Oliveira, Teresa; Rego, A Cristina; Morgadinho, M Teresa; Macedo, Tice R; Oliveira, Catarina R, 2006. Coimbra Médica V. 21 - 29. 1. 2. 2006. http://hdl.handle.net/10316/18520 . published Coimbra Médica V

Endurance training limits the functional alterations of heart rat mitochondria submitted to in vitro anoxia-reoxygenation

Ascensão, A., 2006. International Journal of Cardiology. 169 - 178. 2. 109. 2006. http://www.scopus.com/inward/record.url?eid=2-s2.0-33646109584&partnerID=MN8TOARS . 10.1016/j.ijcard.2005.06.003 . International Journal of Cardiology

Mitochondrial Bioenergetics, Diabetes, and Aging: Top-Down Analysis Using the Diabetic Goto-Kakizaki (GK) Rat as a Model.

Ferreira FM; Moreno AJ; Seiça R; Santos MS; Palmeira CM, 2006. 2006. http://europepmc.org/abstract/med/20021031 . 10.1080/15376520600616925 .

Effects of endurance training and acute doxorubicin treatment on rat heart mitochondrial alterations induced by in vitro anoxia-reoxygenation

Ascensão, A.; Ascensão A; Ferreira R; Oliveira PJ; Magalhães J, 2006. Cardiovascular Toxicology. 159 - 171. 3-4. 6. 2006. http://www.scopus.com/inward/record.url?eid=2-s2.0-33947101036&partnerID=MN8TOARS . 10.1385/ct:6:3:159 . Cardiovascular Toxicology

Mitochondrial dysfunction and caspase activation in rat cortical neurons treated with cocaine or amphetamine

Cunha-Oliveira, T.; Rego, A.C.; Cardoso, S.M.; Borges, F.; Swerdlow, R.H.; Macedo, T.; de Oliveira, C.R., 2006. Brain Research. 44 - 54. 1. 1089. 2006. http://dx.doi.org/10.1016/j.brainres.2006.03.061 . 10.1016/j.brainres.2006.03.061 . published Brain Research

Esterification prevents induction of the mitochondrial permeability transition by N-acetyl perfluorooctane sulfonamides

O'Brien, T.M., 2006. Chemical Research in Toxicology. 1305 - 1312. 10. 19. 2006. http://www.scopus.com/inward/record.url?eid=2-s2.0-33750209492&partnerID=MN8TOARS . 10.1021/tx060132r . Chemical Research in Toxicology

Pt(II) vs Pd(II) polyamine complexes as new anticancer drugs: A structure-activity study

Fiuza, S.M., 2006. Letters in Drug Design and Discovery. 149 - 151. 3. 3. 2006. http://www.scopus.com/inward/record.url?eid=2-s2.0-33645876182&partnerID=MN8TOARS . 10.2174/157018006776286989 . Letters in Drug Design and Discovery

Decreased ANT content in Zucker fatty rats: Relevance for altered hepatic mitochondrial bioenergetics in steatosis

Teodoro, J., 2006. FEBS Letters. 2153 - 2157. 8. 580. 2006. http://www.scopus.com/inward/record.url?eid=2-s2.0-33645241135&partnerID=MN8TOARS . 10.1016/j.febslet.2006.02.078 . FEBS Letters

Depletion of adenine nucleotide translocator protein in heart mitochondria from doxorubicin-treated rats - Relevance for mitochondrial dysfunction

Oliveira, P.J., 2006. Toxicology. 160 - 168. 2-3. 220. 2006. http://www.scopus.com/inward/record.url?eid=2-s2.0-33244492919&partnerID=MN8TOARS . 10.1016/j.tox.2005.12.009 . Toxicology

Doxorubicin-induced thiol-dependent alteration of cardiac mitochondrial permeability transition and respiration

Oliveira, P.J., 2006. Biochemistry (Moscow). 194 - 199. 2. 71. 2006. http://www.scopus.com/inward/record.url?eid=2-s2.0-33645277082&partnerID=MN8TOARS . 10.1134/S000629790602012X . Biochemistry (Moscow)

Synthesis and cytotoxic profile of 3,4-methylenedioxymethamphetamine ("ecstasy") and its metabolites on undifferentiated PC12 cells: A putative structure-toxicity relationship

Milhazes, N.; Cunha-Oliveira, T.; Martins, P.; Garrido, J.; Oliveira, C.; Rego, A.C.; Borges, F., 2006. Chemical Research in Toxicology. 1294 - 1304. 10. 19. 2006. http://www.scopus.com/inward/record.url?eid=2-s2.0-33750209029&partnerID=MN8TOARS . 10.1021/tx060123i . Chemical Research in Toxicology

Differential cytotoxic responses of PC12 cells chronically exposed to psychostimulants or to hydrogen peroxide

Cunha-Oliveira, Teresa; Rego, A. Cristina; Morgadinho, Maria Teresa; Macedo, Tice; Oliveira, Catarina Resende, 2006. Toxicology. 54 - 62. 1. 217. 2006. http://dx.doi.org/10.1016/j.tox.2005.08.022 . 10.1016/j.tox.2005.08.022 . Toxicology

Expression of NR1/NR2B N-methyl-D-aspartate receptors enhances heroin toxicity in HEK293 cells

Domingues, A.; * Oliveira, T.C.; Laço, M.L.N.; Macedo, T.R.A.; Oliveira, C.R.; Rego, A.C., 2006. Annals of the New York Academy of Sciences. 458 - 465. 1074. 2006. http://dx.doi.org/10.1196/annals.1369.046 . 10.1196/annals.1369.046 . published Annals of the New York Academy of Sciences

Bile acids are toxic for isolated cardiac mitochondria: A possible cause for hepatic-derived cardiomyopathies?

Ferreira, M.; Coxito, P.M.; Sardão, V.A.; Palmeira, C.M.; Oliveira, P.J.; Ferreira M; Coxito PM; et al, 2005. Cardiovascular Toxicology. 63 - 73. 1. 5. 2005. http://www.scopus.com/inward/record.url?eid=2-s2.0-18544374442&partnerID=MN8TOARS . 10.1385/CT:5:1:063 . Cardiovascular Toxicology

Mitochondrial function is not affected by renal morphological changes in diabetic goto-kakizaki rat.

Seiça R; Santos DL; Palmeira CM; Moreno AJ; Sena C; Cunha MF; Santos MS, 2005. 2005. http://europepmc.org/abstract/med/20021090 . 10.1080/15376520590968806 .

Are the antioxidant properties of carvedilol important for the protection of cardiac mitochondria?

Oliveira, P.J., 2005. Current Vascular Pharmacology. 147 - 158. 2. 3. 2005. http://www.scopus.com/inward/record.url?eid=2-s2.0-18144430946&partnerID=MN8TOARS . 10.2174/1570161053586903 . Current Vascular Pharmacology

Mitochondrial DNA variants in a Portuguese population of patients with Alzheimer's disease

Grazina, M.; Silva, F.; Santana, I.; Pratas, J.; Santiago, B.; Oliveira, M.; Carreira, I.; Cunha, L.; Oliveira, C., 2005. European Neurology. 121 - 124. 3. 53. 2005. http://www.scopus.com/inward/record.url?eid=2-s2.0-20844462230&partnerID=MN8TOARS . 10.1159/000085555 . European Neurology

Moderate endurance training prevents doxorubicin-induced in vivo mitochondriopathy and reduces the development of cardiac apoptosis

Ascensão, A., 2005. American Journal of Physiology - Heart and Circulatory Physiology. 2 58-2. 289. 2005. http://www.scopus.com/inward/record.url?eid=2-s2.0-23744489541&partnerID=MN8TOARS . 10.1152/ajpheart.01249.2004 . American Journal of Physiology - Heart and Circulatory Physiology

Bile acids are toxic for isolated cardiac mitochondria: a possible cause for hepatic-derived cardiomyopathies?

Ferreira M; Coxito PM; Sardão VA; Palmeira CM; Oliveira PJ; Ferreira, M., 2005. Cardiovascular toxicology. 63 - 73. 1. 5. 2005. http://europepmc.org/abstract/med/15738586 . 10.1385/ct:5:1:063 . Cardiovascular toxicology

Dietary vitamin E decreases doxorubicin-induced oxidative stress without preventing mitochondrial dysfunction

Berthiaume, J.M., 2005. Cardiovascular Toxicology. 257 - 267. 3. 5. 2005. http://www.scopus.com/inward/record.url?eid=2-s2.0-27144450968&partnerID=MN8TOARS . 10.1385/CT:5:3:257 . Cardiovascular Toxicology

Cardiac mitochondrial alterations observed in hyperglycaemic rats--what can we learn from cell biology?

Oliveira PJ; Oliveira, P.J., 2005. Current diabetes reviews. 11 - 21. 1. 1. 2005. http://europepmc.org/abstract/med/18220578 . 10.2174/1573399052952578 . Current diabetes reviews

Mitochondrial dysfunction in autism spectrum disorders: A population-based study

Oliveira, G.; Diogo, L.; Grazina, M.; Garcia, P.; Ataíde, A.; Marques, C.; Miguel, T.; et al, 2005. Developmental Medicine and Child Neurology. 185 - 189. 3. 47. 2005. http://www.scopus.com/inward/record.url?eid=2-s2.0-14044258489&partnerID=MN8TOARS . 10.1017/S0012162205000332 . Developmental Medicine and Child Neurology

Frontotemporal dementia and mitochondrial DNA transitions

Grazina, M.; Silva, F.; Santana, I.; Santiago, B.; Mendes, C.; Simões, M.; Oliveira, M.; Cunha, L.; Oliveira, C., 2004. Neurobiology of Disease. 306 - 311. 2. 15. 2004. http://www.scopus.com/inward/record.url?eid=2-s2.0-1542300730&partnerID=MN8TOARS . 10.1016/j.nbd.2003.11.004 . Neurobiology of Disease

Carvedilol inhibits the mitochondrial permeability transition by an antioxidant mechanism.

Oliveira PJ; Esteves T; Rolo AP; Palmeira CM; Moreno AJ, 2004. 2004. http://europepmc.org/abstract/med/15034201 . 10.1385/CT:4:1:11 .

Vitamin E or coenzyme Q10 administration is not fully advantageous for heart mitochondrial function in diabetic goto kakizaki rats.

Oliveira PJ; Seica R; Santos DL; Rolo AP; Sardao VA; Ferreira FM; Palmeira CM; Santos MS; Moreno AJ, 2004. 2004. http://europepmc.org/abstract/med/16120365 . 10.1016/j.mito.2004.02.005 .

Advantages in the use of carvedilol versus propranolol for the protection of cardiac mitochondrial function.

Oliveira PJ; Rolo AP; Sardão VA; Monteiro P; Gonçalves L; Providência LA; Palmeira CM; et al, 2004. Revista Portuguesa de Cardiologia. 1291 - 1298. 10. 23. 2004. http://europepmc.org/abstract/med/15641294 . Revista Portuguesa de Cardiologia

Role of mitochondrial dysfunction in combined bile acid-induced cytotoxicity: the switch between apoptosis and necrosis.

Rolo AP; Palmeira CM; Holy JM; Wallace KB, 2004. 2004. http://europepmc.org/abstract/med/14976352 . 10.1093/toxsci/kfh078 .

Mitochondrially-mediated toxicity of bile acids.

Palmeira CM; Rolo AP, 2004. 2004. http://europepmc.org/abstract/med/15363577 . 10.1016/j.tox.2004.06.001 .

Carvedilol-mediated antioxidant protection against doxorubicin-induced cardiac mitochondrial toxicity

Oliveira, P.J., 2004. Toxicology and Applied Pharmacology. 159 - 168. 2. 200. 2004. http://www.scopus.com/inward/record.url?eid=2-s2.0-5144227343&partnerID=MN8TOARS . 10.1016/j.taap.2004.04.005 . Toxicology and Applied Pharmacology

Carvedilol Inhibits the Mitochondrial Permeability Transition by an Antioxidant Mechanism

Oliveira, P.J., 2004. Cardiovascular Toxicology. 11 - 20. 1. 4. 2004. http://www.scopus.com/inward/record.url?eid=2-s2.0-1942486470&partnerID=MN8TOARS . 10.1385/CT:4:1:11 . Cardiovascular Toxicology

Calcium-dependent mitochondrial permeability transition is augmented in the kidney of Goto-Kakizaki diabetic rat

Oliveira, P.J., 2004. Diabetes/Metabolism Research and Reviews. 131 - 136. 2. 20. 2004. http://www.scopus.com/inward/record.url?eid=2-s2.0-1842853998&partnerID=MN8TOARS . 10.1002/dmrr.423 . Diabetes/Metabolism Research and Reviews

Vitamin E or coenzyme Q10 administration is not fully advantageous for heart mitochondrial function in diabetic goto kakizaki rats

Oliveira, P.J., 2004. Mitochondrion. 337 - 345. 6. 3. 2004. http://www.scopus.com/inward/record.url?eid=2-s2.0-1942484378&partnerID=MN8TOARS . 10.1016/j.mito.2004.02.005 . Mitochondrion

Advantages in the use of carvedilol versus propranolol for the protection of cardiac mitochondrial function.

Oliveira PJ; Rolo AP; Sardão VA; Monteiro P; Gonçalves L; Providência LA; Palmeira CM; Moreno AJ; Oliveira, P.J., 2004. Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology. 1291 - 1298. 10. 23. 2004. http://europepmc.org/abstract/med/15641294 . Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology

Protection against post-ischemic mitochondrial injury in rat liver by silymarin or TUDC.

Rolo AP; Oliveira PJ; Moreno AJ; Palmeira CM, 2003. 2003. http://europepmc.org/abstract/med/12850694 . 10.1016/S1386-6346(03)00108-6 .

Protection against post-ischemic mitochondrial injury in rat liver by silymarin or TUDC

Rolo, A.P., 2003. Hepatology Research. 217 - 224. 3. 26. 2003. http://www.scopus.com/inward/record.url?eid=2-s2.0-0042167601&partnerID=MN8TOARS . 10.1016/S1386-6346(03)00108-6 . Hepatology Research

Reduction in cardiac mitochondrial calcium loading capacity is observable during a-naphthylisothiocyanate-induced acute cholestasis: A clue for hepatic-derived cardiomyopathies?

Oliveira, P.J., 2003. Biochimica et Biophysica Acta - Molecular Basis of Disease. 39 - 45. 1. 1637. 2003. http://www.scopus.com/inward/record.url?eid=2-s2.0-0037454702&partnerID=MN8TOARS . 10.1016/S0925-4439(02)00212-0 . Biochimica et Biophysica Acta - Molecular Basis of Disease

Chronic cholestasis and cardiac mitochondrial function in wistar rats: A model for cardiovascular alterations in chronic liver disease? | Colestase crónica e funçá~o mitocondrial cardíaca em ratos wistar: Um modelo para alterações cardiovasculares no contexto de doenças hepáticas crónicas?

Oliveira, P.J.; Rolo, A.P.; Seiça, R.; Santos, M.S.; Palmeira, C.M.; Moreno, A.J., 2003. Revista Portuguesa de Cardiologia. 67 - 75. 1. 22. 2003. http://www.scopus.com/inward/record.url?eid=2-s2.0-0344951202&partnerID=MN8TOARS . Revista Portuguesa de Cardiologia

Chenodexycholate induction of mitochondrial permeability transition pore is associated with increased membrane fluidity and cytochrome c release: Protective role of carvedilol

Rolo, A.P., 2003. Mitochondrion. 305 - 311. 4. 2. 2003. http://www.scopus.com/inward/record.url?eid=2-s2.0-0037347309&partnerID=MN8TOARS . 10.1016/S1567-7249(03)00007-2 . Mitochondrion

Chronic cholestasis and cardiac mitochondrial function in wistar rats: A model for cardiovascular alterations in chronic liver disease? | Colestase crónica e funçá~o mitocondrial cardíaca em ratos wistar: Um modelo para alterações cardiovasculares no contexto de doenças hepáticas crónicas?

Oliveira, P.J., 2003. Revista Portuguesa de Cardiologia. 67 - 75. 1. 22. 2003. http://www.scopus.com/inward/record.url?eid=2-s2.0-0344951202&partnerID=MN8TOARS . Revista Portuguesa de Cardiologia

Diabetes induces metabolic adaptations in rat liver mitochondria: Role of coenzyme Q and cardiolipin contents

Ferreira, F.M., 2003. Biochimica et Biophysica Acta - Molecular Basis of Disease. 113 - 120. 2. 1639. 2003. http://www.scopus.com/inward/record.url?eid=2-s2.0-0642345079&partnerID=MN8TOARS . 10.1016/j.bbadis.2003.08.001 . Biochimica et Biophysica Acta - Molecular Basis of Disease

Enhanced permeability transition explains the reduced calcium uptake in cardiac mitochondria from streptozotocin-induced diabetic rats

Oliveira, P.J., 2003. FEBS Letters. 511 - 514. 3. 554. 2003. http://www.scopus.com/inward/record.url?eid=2-s2.0-0242541631&partnerID=MN8TOARS . 10.1016/S0014-5793(03)01233-X . FEBS Letters

Histological changes and impairment of liver mitochondrial bioenergetics after long-term treatment with a-naphthyl-isothiocyanate (ANIT)

Palmeira, C.M., 2003. Toxicology. 185 - 196. 3. 190. 2003. http://www.scopus.com/inward/record.url?eid=2-s2.0-0042133192&partnerID=MN8TOARS . 10.1016/S0300-483X(03)00163-X . Toxicology

Mitochondria: Role in ischemia, reperfusion and cell death | Mitocôndrias: Que papel na isquémia, reperfusão e morte celular?

Monteiro, P., 2003. Revista Portuguesa de Cardiologia. 233 - 254. 2. 22. 2003. http://www.scopus.com/inward/record.url?eid=2-s2.0-0037732545&partnerID=MN8TOARS . Revista Portuguesa de Cardiologia

Carvedilol: Relation between antioxidant activity and inhibition of the mitochondrial permeability transition | Carvedilol: Relação entre a actividade antioxidante e inibição da transição de permeabilidade mitocondrial

Oliveira, P.J.; Esteves, T.; Rolo, A.P.; Monteiro, P.; Gonçalves, L.; Palmeira, C.M.; Moreno, A.J., 2003. Revista Portuguesa de Cardiologia. 55 - 62. 1. 22. 2003. http://www.scopus.com/inward/record.url?eid=2-s2.0-0346034614&partnerID=MN8TOARS . Revista Portuguesa de Cardiologia

Cardiac mitochondrial calcium loading capacity is severely affected after chronic cholestasis in Wistar rats

Oliveira, P.J.; Oliveira PJ; Rolo AP; Seiça R; Santos MS; Palmeira CM; Moreno AJ, 2003. Journal of Investigative Medicine. 86 - 94. 2. 51. 2003. http://www.scopus.com/inward/record.url?eid=2-s2.0-0037338705&partnerID=MN8TOARS . Journal of Investigative Medicine

Pharmacological modulation of mitochondrial function during ischemia and reperfusion | Modulação farmacológica da função mitocondrial no contexto da isquemia e reperfusão

Monteiro, P., 2003. Revista Portuguesa de Cardiologia. 407 - 429. 3. 22. 2003. http://www.scopus.com/inward/record.url?eid=2-s2.0-0038795126&partnerID=MN8TOARS . Revista Portuguesa de Cardiologia

Chronic cholestasis and cardiac mitochondrial function in Wistar rats: a model for cardiovascular alterations in chronic liver disease?

Oliveira PJ; Rolo AP; Seiça R; Santos MS; Palmeira CM; Moreno AJ, 2003. Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology. 2003. http://europepmc.org/abstract/med/12712811 . Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology

Carvedilol: Relation between antioxidant activity and inhibition of the mitochondrial permeability transition | Carvedilol: Relação entre a actividade antioxidante e inibição da transição de permeabilidade mitocondrial

Oliveira, P.J., 2003. Revista Portuguesa de Cardiologia. 55 - 62. 1. 22. 2003. http://www.scopus.com/inward/record.url?eid=2-s2.0-0346034614&partnerID=MN8TOARS . Revista Portuguesa de Cardiologia

Carvedilol: relation between antioxidant activity and inhibition of the mitochondrial permeability transition.

Oliveira PJ; Esteves T; Rolo AP; Monteiro P; Gonçalves L; Palmeira CM; Moreno AJ, 2003. Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology. 2003. http://europepmc.org/abstract/med/12712810 . Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology

Mitochondria: role in ischemia, reperfusion and cell death.

Monteiro P; Oliveira PJ; Gonçalves L; Providência LA, 2003. Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology. 2003. http://europepmc.org/abstract/med/12769003 . Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology

Cholestasis induced by chronic treatment with alpha-naphthyl-isothiocyanate (ANIT) affects rat renal mitochondrial bioenergetics.

Ferreira FM; Oliveira PJ; Rolo AP; Santos MS; Moreno AJ; da Cunha MF; Seiça R; Palmeira CM; Ferreira, F.M., 2003. Archives of Toxicology. 194 - 200. 4. 77. 2003. http://europepmc.org/abstract/med/12698234 . Archives of Toxicology

Parkinson's disease and mitochondrial DNA NADH dehydrogenase subunit 1 nucleotides 3337-3340: Study in a population from the central region of Portugal (Coimbra)

Grazina, M.; Silva, F.; Januário, C.; Oliveira, M.; Cunha, L.; Oliveira, C., 2003. European Neurology. 60 - 61. 1. 50. 2003. http://www.scopus.com/inward/record.url?eid=2-s2.0-0038307365&partnerID=MN8TOARS . 10.1159/000070863 . European Neurology

Drugs of abuse induce apoptotic features in PC12 cells

Cunha-Oliveira, T.; Rego, A.C.; Macedo, T.; Oliveira, C.R., 2003. Annals of the New York Academy of Sciences. 667 - 670. 1. 1010. 2003. http://dx.doi.org/10.1196/annals.1299.121 . 10.1196/annals.1299.121 . published Annals of the New York Academy of Sciences

Chenodeoxycholate induction of mitochondrial permeability transition pore is associated with increased membrane fluidity and cytochrome c release: protective role of carvedilol.

Rolo AP; Oliveira PJ; Moreno AJ; Palmeira CM, 2003. 2003. http://europepmc.org/abstract/med/16120330 . 10.1016/S1567-7249(03)00007-2 .

Carvedilol: relation between antioxidant activity and inhibition of the mitochondrial permeability transition.

Oliveira PJ; Esteves T; Rolo AP; Monteiro P; Gonçalves L; Palmeira CM; Moreno AJ, 2003. 2003. http://europepmc.org/abstract/med/12712810 .

Reduction in cardiac mitochondrial calcium loading capacity is observable during alpha-naphthylisothiocyanate-induced acute cholestasis: a clue for hepatic-derived cardiomyopathies?

Oliveira PJ; Rolo AP; Seiça R; Santos MS; Palmeira CM; Moreno AJ, 2003. 2003. http://europepmc.org/abstract/med/12527405 . 10.1016/S0925-4439(02)00212-0 .

Cardiac mitochondrial calcium loading capacity is severely affected after chronic cholestasis in Wistar rats.

Oliveira PJ; Rolo AP; Seiça R; Santos MS; Palmeira CM; Moreno AJ; Oliveira, P.J.; et al, 2003. Journal of Investigative Medicine. 86 - 94. 2. 51. 2003. http://europepmc.org/abstract/med/12643513 . Journal of Investigative Medicine

Mitochondrially mediated synergistic cell killing by bile acids.

Rolo AP; Palmeira CM; Wallace KB, 2003. 2003. http://europepmc.org/abstract/med/12527417 . 10.1016/S0925-4439(02)00224-7 .

Cholestasis induced by chronic treatment with alpha-naphthyl-isothiocyanate (ANIT) affects rat renal mitochondrial bioenergetics.

Ferreira FM; Oliveira PJ; Rolo AP; Santos MS; Moreno AJ; da Cunha MF; Seiça R; et al, 2003. Archives of Toxicology. 194 - 200. 4. 77. 2003. http://europepmc.org/abstract/med/12698234 . 10.1007/s00204-003-0441-3 . Archives of Toxicology

Diabetes induces metabolic adaptations in rat liver mitochondria: role of coenzyme Q and cardiolipin contents.

Ferreira FM; Seiça R; Oliveira PJ; Coxito PM; Moreno AJ; Palmeira CM; Santos MS, 2003. 2003. http://europepmc.org/abstract/med/14559118 . 10.1016/j.bbadis.2003.08.001 .

Chronic cholestasis and cardiac mitochondrial function in Wistar rats: a model for cardiovascular alterations in chronic liver disease?

Oliveira PJ; Rolo AP; Seiça R; Santos MS; Palmeira CM; Moreno AJ, 2003. 2003. http://europepmc.org/abstract/med/12712811 .

Diabetes and mitochondrial oxidative stress: a study using heart mitochondria from the diabetic Goto-Kakizaki rat.

Santos DL; Palmeira CM; Seiça R; Dias J; Mesquita J; Moreno AJ; Santos MS, 2003. 2003. http://europepmc.org/abstract/med/12841358 . 10.1023/A:1023475022025 .

Enhanced permeability transition explains the reduced calcium uptake in cardiac mitochondria from streptozotocin-induced diabetic rats.

Oliveira PJ; Seiça R; Coxito PM; Rolo AP; Palmeira CM; Santos MS; Moreno AJ, 2003. 2003. http://europepmc.org/abstract/med/14623121 . 10.1016/S0014-5793(03)01233-X .

Diabetes and mitochondrial bioenergetics: alterations with age.

Ferreira FM; Palmeira CM; Seiça R; Moreno AJ; Santos MS, 2003. 2003. http://europepmc.org/abstract/med/12898645 . 10.1002/jbt.10081 .

Histological changes and impairment of liver mitochondrial bioenergetics after long-term treatment with alpha-naphthyl-isothiocyanate (ANIT).

Palmeira CM; Ferreira FM; Rolo AP; Oliveira PJ; Santos MS; Moreno AJ; Cipriano MA; Martins MI; Seiça R, 2003. 2003. http://europepmc.org/abstract/med/12927374 . 10.1016/S0300-483X(03)00163-X .

Toxic effects of opioid and stimulant drugs on undifferentiated PC12 cells

# Cunha-Oliveira, T.; Rego, A.C.; Morgadinho, M.T.; Macedo, T.R.A.; Oliveira, C.R., 2002. Annals of the New York Academy of Sciences. 487 - 496. 965. 2002. http://www.scopus.com/inward/record.url?eid=2-s2.0-0036290212&partnerID=MN8TOARS . 10.1111/j.1749-6632.2002.tb04190.x . published Annals of the New York Academy of Sciences

Study of carvedilol by combined Raman spectroscopy and ab initio MO calculations

Marques, M.P.M., 2002. Journal of Raman Spectroscopy. 778 - 783. 10. 33. 2002. http://www.scopus.com/inward/record.url?eid=2-s2.0-0036773098&partnerID=MN8TOARS . 10.1002/jrs.916 . Journal of Raman Spectroscopy

Interactions of combined bile acids on hepatocyte viability: cytoprotection or synergism.

Rolo AP; Palmeira CM; Wallace KB, 2002. 2002. http://europepmc.org/abstract/med/11814708 . 10.1016/S0378-4274(01)00464-7 .

Caffeine enhances the calcium-dependent cardiac mitochondrial permeability transition: Relevance for caffeine toxicity

Sardão, V.A., 2002. Toxicology and Applied Pharmacology. 50 - 56. 1. 179. 2002. http://www.scopus.com/inward/record.url?eid=2-s2.0-0037082662&partnerID=MN8TOARS . 10.1006/taap.2001.9334 . Toxicology and Applied Pharmacology

Impact of carvedilol on the mitochondrial damage induced by hypoxanthine and xantine oxidase--what role in myocardial ischemia and reperfusion?

Oliveira PJ; Rolo AP; Monteiro P; Gonçalves L; Palmeira CM; Moreno AJ, 2002. 2002. http://europepmc.org/abstract/med/12621918 .

Disruption of mitochondrial calcium homeostasis after chronic a-naphthylisothiocyanate administration: Relevance for cholestasis

Rolo, A.P.; Rolo AP; Oliveira PJ; Seiça R; Santos MS; Moreno AJ; Palmeira CM, 2002. Journal of Investigative Medicine. 193 - 200. 3. 50. 2002. http://www.scopus.com/inward/record.url?eid=2-s2.0-0036092085&partnerID=MN8TOARS . Journal of Investigative Medicine

Impact of diabetes on induction of the mitochondrial permeability transition.

Oliveira PJ; Rolo AP; Seiça R; Sardão V; Monteiro P; Gonçalves L; Providência L; et al, 2002. Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology. 759 - 766. 6. 21. 2002. http://europepmc.org/abstract/med/12194377 . Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology

Improved efficiency of hepatic mitochondrial function in rats with cholestasis induced by an acute dose of alpha-naphthylisothiocyanate.

Rolo AP; Oliveira PJ; Seiça R; Santos MS; Moreno AJ; Palmeira CM, 2002. 2002. http://europepmc.org/abstract/med/12127259 . 10.1006/taap.2002.9434 .

Impact of carvedilol on the mitochondrial damage induced by hypoxanthine and xantine oxidase - What role in myocardial ischemia and reperfusion? | Impacto do carvedilol sobre o dano mitocondrial induzido por hipoxantina/xantina oxidase - Que papel na isquemia e reperfusão do miocárdio?

Oliveira, P.J., 2002. Revista Portuguesa de Cardiologia. 1447 - 1455. 12. 21. 2002. http://www.scopus.com/inward/record.url?eid=2-s2.0-0036998602&partnerID=MN8TOARS . Revista Portuguesa de Cardiologia

Impact of diabetes on induction of the mitochondrial permeability transition.

Oliveira PJ; Rolo AP; Seiça R; Sardão V; Monteiro P; Gonçalves L; Providência L; et al, 2002. Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology. 759 - 766. 6. 21. 2002. http://europepmc.org/abstract/med/12194377 . Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology

Improved efficiency of hepatic mitochondrial function in rats with cholestasis induced by an acute dose of a-naphthylisothiocyanate

Rolo, A.P., 2002. Toxicology and Applied Pharmacology. 20 - 26. 1. 182. 2002. http://www.scopus.com/inward/record.url?eid=2-s2.0-0036070550&partnerID=MN8TOARS . 10.1006/taap.2002.9434 . Toxicology and Applied Pharmacology

Impact of carvedilol on the mitochondrial damage induced by hypoxanthine and xantine oxidase--what role in myocardial ischemia and reperfusion?

Oliveira PJ; Rolo AP; Monteiro P; Gonçalves L; Palmeira CM; Moreno AJ, 2002. Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology. 2002. http://europepmc.org/abstract/med/12621918 . Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology

Disruption of mitochondrial calcium homeostasis after chronic a-naphthylisothiocyanate administration: Relevance for cholestasis

Rolo, A.P.; Oliveira, P.J.; Seiça, R.; Santos, M.S.; Moreno, A.J.; Palmeira, C.M.; Rolo AP; et al, 2002. Journal of Investigative Medicine. 193 - 200. 3. 50. 2002. http://www.scopus.com/inward/record.url?eid=2-s2.0-0036092085&partnerID=MN8TOARS . Journal of Investigative Medicine

Impact of carvedilol on the mitochondrial damage induced by hypoxanthine and xantine oxidase - What role in myocardial ischemia and reperfusion? | Impacto do carvedilol sobre o dano mitocondrial induzido por hipoxantina/xantina oxidase - Que papel na isquemia e reperfusão do miocárdio?

Oliveira, P.J.; Rolo, A.P.; Monteiro, P.; Conçalves, L.; Palmeira, C.M.; Moreno, A.J., 2002. Revista Portuguesa de Cardiologia. 1447 - 1455. 12. 21. 2002. http://www.scopus.com/inward/record.url?eid=2-s2.0-0036998602&partnerID=MN8TOARS . Revista Portuguesa de Cardiologia

Inhibitory effect of carvedilol in the high-conductance state of the mitochondrial permeability transition pore

Oliveira, P.J., 2001. European Journal of Pharmacology. 231 - 237. 3. 412. 2001. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035793307&partnerID=MN8TOARS . 10.1016/S0014-2999(01)00745-2 . European Journal of Pharmacology

Decreased susceptibility of heart mitochondria from diabetic GK rats to mitochondrial permeability transition induced by calcium phosphate

Oliveira, P.J.; Oliveira PJ; Rolo AP; Seiça R; Palmeira CM; Santos MS; Moreno AJ, 2001. Bioscience Reports. 45 - 53. 1. 21. 2001. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034905572&partnerID=MN8TOARS . 10.1023/a:1010482017540 . Bioscience Reports

Protective effect of carvedilol on chenodeoxycholate induction of the permeability transition pore

Rolo, A.P.; Oliveira, P.J.; Moreno, A.J.M.; Palmeira, C.M., 2001. Biochemical Pharmacology. 1449 - 1454. 11. 61. 2001. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035370544&partnerID=MN8TOARS . 10.1016/S0006-2952(01)00620-7 . Biochemical Pharmacology

Chenodeoxycholate is a potent inducer of the permeability transition pore in rat liver mitochondria

Rolo, A.P.; Oliveira, P.J.; Moreno, A.J.M.; Palmeira, C.M., 2001. Bioscience Reports. 73 - 80. 1. 21. 2001. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034899577&partnerID=MN8TOARS . 10.1023/A:1010438202519 . Bioscience Reports

Chenodeoxycholate is a potent inducer of the permeability transition pore in rat liver mitochondria

Rolo, A.P., 2001. Bioscience Reports. 73 - 80. 1. 21. 2001. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034899577&partnerID=MN8TOARS . 10.1023/A:1010438202519 . Bioscience Reports

Carvedilol reduces mitochondrial damage induced by hypoxanthine/xanthine oxidase: Relevance to hypoxia/reoxygenation injury

Oliveira, P.J., 2001. Cardiovascular Toxicology. 205 - 213. 3. 1. 2001. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035750084&partnerID=MN8TOARS . 10.1385/CT:1:3:205 . Cardiovascular Toxicology

Decreased susceptibility of heart mitochondria from diabetic GK rats to mitochondrial permeability transition induced by calcium phosphate.

Oliveira PJ; Rolo AP; Seiça R; Palmeira CM; Santos MS; Moreno AJ; Oliveira, P.J.; et al, 2001. Bioscience Reports. 45 - 53. 1. 21. 2001. http://europepmc.org/abstract/med/11508693 . 10.1023/a:1010482017540 . Bioscience Reports

Carvedilol in heart mitochondria - Protonophore or opener of the mitochondrial K<inf>ATP</inf> channels?

Oliveira, P.J.; Rolo, A.P.; Sardão, V.A.; Coxito, P.M.; Palmeira, C.M.; Moreno, A.J.M., 2001. Life Sciences. 123 - 132. 2. 69. 2001. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035371154&partnerID=MN8TOARS . 10.1016/S0024-3205(01)01109-2 . Life Sciences

Enhanced mitochondrial testicular antioxidant capacity in Goto-Kakizaki diabetic rats: Role of coenzyme Q

Palmeira, C.M.; Santos, D.L.; Seiça, R.; Moreno, A.J.; Santos, M.S.; Palmeira CM; Santos DL; et al, 2001. American Journal of Physiology - Cell Physiology. 3 50-3. 281. 2001. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034838234&partnerID=MN8TOARS . American Journal of Physiology - Cell Physiology

Inhibitory effect of carvedilol in the high-conductance state of the mitochondrial permeability transition pore

Oliveira, P.J.; Coxito, P.M.; Rolo, A.P.; Santos, D.L.; Palmeira, C.M.; Moreno, A.J.M., 2001. European Journal of Pharmacology. 231 - 237. 3. 412. 2001. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035793307&partnerID=MN8TOARS . 10.1016/S0014-2999(01)00745-2 . European Journal of Pharmacology

Carvedilol reduces mitochondrial damage induced by hypoxanthine/xanthine oxidase: Relevance to hypoxia/reoxygenation injury

Oliveira, P.J.; Rolo, A.P.; Palmeira, C.M.; Moreno, A.J.M., 2001. Cardiovascular Toxicology. 205 - 213. 3. 1. 2001. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035750084&partnerID=MN8TOARS . 10.1385/CT:1:3:205 . Cardiovascular Toxicology

Carvedilol in heart mitochondria - Protonophore or opener of the mitochondrial KATP channels?

Oliveira, P.J., 2001. Life Sciences. 123 - 132. 2. 69. 2001. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035371154&partnerID=MN8TOARS . 10.1016/S0024-3205(01)01109-2 . Life Sciences

Brain and liver mitochondria isolated from diabetic Goto-Kakizaki rats show different susceptibility to induced oxidative stress

Santos, M.S.; Santos, D.L.; Palmeira, C.M.; Seiça, R.; Moreno, A.J.; Oliveira, C.R., 2001. Diabetes/Metabolism Research and Reviews. 223 - 230. 3. 17. 2001. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034944055&partnerID=MN8TOARS . 10.1002/dmrr.200 . Diabetes/Metabolism Research and Reviews

Prion Human Diseases: 14-3-3 Protein Utility in the Diagnosis

Grazina, Manuela; Silva, FMP; Oliveira, CR, 2001. Sinapse. 10 - 16. 1. 1. 2001. published Sinapse

Protective effect of carvedilol on chenodeoxycholate induction of the permeability transition pore

Rolo, A.P., 2001. Biochemical Pharmacology. 1449 - 1454. 11. 61. 2001. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035370544&partnerID=MN8TOARS . 10.1016/S0006-2952(01)00620-7 . Biochemical Pharmacology

Doxorubicin-induced persistent oxidative stress to cardiac myocytes

Zhou, S.; Palmeira, C.M.; Wallace, K.B., 2001. Toxicology Letters. 151 - 157. 3. 121. 2001. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035912594&partnerID=MN8TOARS . 10.1016/S0378-4274(01)00329-0 . Toxicology Letters

Bile acids affect liver mitochondrial bioenergetics: possible relevance for cholestasis therapy.

Rolo AP; Oliveira PJ; Moreno AJ; Palmeira CM; Rolo, A.P.; Oliveira, P.J.; Moreno, A.J.M.; Palmeira, C.M., 2000. Toxicological Sciences. 177 - 185. 1. 57. 2000. http://europepmc.org/abstract/med/10966524 . 10.1093/toxsci/57.1.177 . Toxicological Sciences

Effects of carvedilol on isolated heart mitochondria: Evidence for a protonophoretic mechanism

Oliveira, P.J., 2000. Biochemical and Biophysical Research Communications. 82 - 87. 1. 276. 2000. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034675219&partnerID=MN8TOARS . 10.1006/bbrc.2000.3374 . Biochemical and Biophysical Research Communications

Bile acids affect liver mitochondrial bioenergetics: possible relevance for cholestasis therapy.

Rolo AP; Oliveira PJ; Moreno AJ; Palmeira CM, 2000. 2000. http://europepmc.org/abstract/med/10966524 . 10.1093/toxsci/57.1.177 .

Induction of the mitochondrial permeability transition in vitro by short-chain carboxylic acids

Palmeira, C.M.; Rana, M.I.; Frederick, C.B.; Wallace, K.B., 2000. Biochemical and Biophysical Research Communications. 431 - 435. 2. 272. 2000. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034616658&partnerID=MN8TOARS . 10.1006/bbrc.2000.2797 . Biochemical and Biophysical Research Communications

Cholestasis and mitochondrial dysfunction: A review

Rolo, A.P.; Palmeira, C.M., 2000. Toxic Substance Mechanisms. 83 - 98. 2. 19. 2000. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034458883&partnerID=MN8TOARS . 10.1080/10769180052008878 . Toxic Substance Mechanisms

Carvedilol inhibits the exogenous NADH dehydrogenase in rat heart mitochondria

Oliveira, P.J., 2000. Archives of Biochemistry and Biophysics. 279 - 285. 2. 374. 2000. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034652094&partnerID=MN8TOARS . 10.1006/abbi.1999.1624 . Archives of Biochemistry and Biophysics

Influence of apolipoprotein E genotype on blood redox status of Alzheimer's disease patients.

Fernandes MA; Proenca MT; Nogueira AJ; Grazina MM; Oliveira LM; Fernandes AI; Santiago B; et al, 1999. International journal of molecular medicine. 179 - 186. 2. 4. 1999. http://europepmc.org/abstract/med/10402486 . International journal of molecular medicine

Decreased susceptibility to lipid peroxidation of Goto-Kakizaki rats: Relationship to mitochondrial antioxidant capacity

Ferreira, F.M.L.; Palmeira, C.M.; Matos, M.J.; Seiç, R.; Santos, M.S., 1999. Life Sciences. 1013 - 1025. 10. 65. 1999. http://www.scopus.com/inward/record.url?eid=2-s2.0-0033618489&partnerID=MN8TOARS . 10.1016/S0024-3205(99)00332-X . Life Sciences

Cardioselective and cumulative oxidation of mitochondrial DNA following subchronic doxorubicin administration

Serrano, J.; Palmeira, C.M.; Kuehl, D.W.; Wallace, K.B., 1999. Biochimica et Biophysica Acta - Bioenergetics. 201 - 205. 1. 1411. 1999. http://www.scopus.com/inward/record.url?eid=2-s2.0-0032961434&partnerID=MN8TOARS . 10.1016/S0005-2728(99)00011-0 . Biochimica et Biophysica Acta - Bioenergetics

Higher efficiency of the liver phosphorylative system in diabetic Goto-Kakizaki (GK) rats

Palmeira, C.M.; Ferreira, F.M.L.; Santos, D.L.; Ceiça, R.; Suzuki, K.-I.; Santos, M.S., 1999. FEBS Letters. 103 - 106. 2. 458. 1999. http://www.scopus.com/inward/record.url?eid=2-s2.0-0032842698&partnerID=MN8TOARS . 10.1016/S0014-5793(99)01144-8 . FEBS Letters

Alterations of liver mitochondrial bioenergetics in diabetic Goto- Kakizaki rats

Ferreira, F.M.L.; Palmeira, C.M.; Seiça, R.; Santos, M.S., 1999. Metabolism: Clinical and Experimental. 1115 - 1119. 9. 48. 1999. http://www.scopus.com/inward/record.url?eid=2-s2.0-0032857256&partnerID=MN8TOARS . 10.1016/S0026-0495(99)90124-5 . Metabolism: Clinical and Experimental

Herbicide-induced mitochondrial and cellular liver toxicity: A review of paraquat, dinoseb, and 2,4-D effects

Palmeira, C.M., 1999. Toxic Substance Mechanisms. 187 - 204. 4. 18. 1999. http://www.scopus.com/inward/record.url?eid=2-s2.0-0033457940&partnerID=MN8TOARS . 10.1080/107691899229070 . Toxic Substance Mechanisms

Age-related alterations in liver mitochondrial bioenergetics of diabetic Goto-Kakizaki rats.

Ferreira FM; Seiça R; Santos MS; Palmeira CM; Ferreira, F.M.L.; Seiça, R.; Santos, M.S.; Palmeira, C.M., 1999. Acta Diabetologica. 173 - 177. 4. 36. 1999. http://europepmc.org/abstract/med/10664324 . 10.1007/s005920050163 . Acta Diabetologica

Ischemic heart disease: The role of mitochondria - Carvedilol prevents lipid peroxidation of mitochondrial membranes

Moreno, A.J.M.; Santos, D.J.S.L.; Palmeira, C.M.; Moreno AJ; Santos DJ; Palmeira CM, 1998. Revista Portuguesa de Cardiologia. 63 - 77. SUPPL. 2. 17. 1998. http://www.scopus.com/inward/record.url?eid=2-s2.0-0031759966&partnerID=MN8TOARS . Revista Portuguesa de Cardiologia

Acrylic acid induces the glutathione-independent mitochondrial permeability transition in vitro

Custodio, J.B.A.; Palmeira, C.M.; Moreno, A.J.; Wallace, K.B., 1998. Toxicological Sciences. 19 - 27. 1. 43. 1998. http://www.scopus.com/inward/record.url?eid=2-s2.0-0031831694&partnerID=MN8TOARS . 10.1006/toxs.1998.2448 . Toxicological Sciences

Benzoquinone inhibits the voltage-dependent induction of the mitochondrial permeability transition caused by redox-cycling naphthoquinones

Palmeira, C.M.; Wallace, K.B., 1997. Toxicology and Applied Pharmacology. 338 - 347. 2. 143. 1997. http://www.scopus.com/inward/record.url?eid=2-s2.0-0030932708&partnerID=MN8TOARS . 10.1006/taap.1996.8099 . Toxicology and Applied Pharmacology

Preferential oxidation of cardiac mitochondrial DNA following acute intoxication with doxorubicin

Palmeira, C.M.; Serrano, J.; Kuehl, D.W.; Wallace, K.B., 1997. Biochimica et Biophysica Acta - Bioenergetics. 101 - 106. 2. 1321. 1997. http://www.scopus.com/inward/record.url?eid=2-s2.0-0030880285&partnerID=MN8TOARS . 10.1016/S0005-2728(97)00055-8 . Biochimica et Biophysica Acta - Bioenergetics

Mercuric chloride toxicity in rat liver mitochondria and isolated hepatocytes

Palmeira, C.M.; Madeira, V.M.C., 1997. Environmental Toxicology and Pharmacology. 229 - 235. 3. 3. 1997. http://www.scopus.com/inward/record.url?eid=2-s2.0-0030758726&partnerID=MN8TOARS . 10.1016/S1382-6689(97)00018-5 . Environmental Toxicology and Pharmacology

Determination of 8-hydroxydeoxyguanosine in biological tissue by liquid chromatography/electrospray ionization-mass spectrometry/mass spectrometry

Serrano, J.; Palmeira, C.M.; Wallace, K.B.; Kuehl, D.W., 1996. Rapid Communications in Mass Spectrometry. 1789 - 1791. 14. 10. 1996. http://www.scopus.com/inward/record.url?eid=2-s2.0-0030478989&partnerID=MN8TOARS . 10.1002/(SICI)1097-0231(199611)10:14<1789::AID-RCM752>3.0.CO;2-6 . Rapid Communications in Mass Spectrometry

Continuous monitoring of mitochondrial membrane potential in hepatocyte cell suspensions

Palmeira, C.M.; Moreno, A.J.M.; Madeira, V.M.C.; Wallace, K.B., 1996. Journal of Pharmacological and Toxicological Methods. 35 - 43. 1. 35. 1996. http://www.scopus.com/inward/record.url?eid=2-s2.0-0029925338&partnerID=MN8TOARS . 10.1016/1056-8719(95)00131-X . Journal of Pharmacological and Toxicological Methods

Effects of paraquat, dinoseb and 2,4-D on intracellular calcium and on vasopressin-induced calcium mobilization in isolated hepatocytes

Palmeira, C.M.; Moreno, A.J.; Madeira, V.M.C., 1995. Archives of Toxicology. 460 - 466. 7. 69. 1995. http://www.scopus.com/inward/record.url?eid=2-s2.0-0029054234&partnerID=MN8TOARS . 10.1007/s002040050199 . Archives of Toxicology

Mitochondrial bioenergetics is affected by the herbicide paraquat

Palmeira, C.M.; Moreno, A.J.; Madeira, V.M.C., 1995. Biochimica et Biophysica Acta - Bioenergetics. 187 - 192. 2. 1229. 1995. http://www.scopus.com/inward/record.url?eid=2-s2.0-0028961733&partnerID=MN8TOARS . 10.1016/0005-2728(94)00202-G . Biochimica et Biophysica Acta - Bioenergetics

Thiols metabolism is altered by the herbicides paraquat, dinoseb and 2,4-D: A study in isolated hepatocytes

Palmeira, C.M.; Moreno, A.J.; Madeira, V.M.C., 1995. Toxicology Letters. 115 - 123. 2-3. 81. 1995. http://www.scopus.com/inward/record.url?eid=2-s2.0-0029590153&partnerID=MN8TOARS . 10.1016/0378-4274(95)03414-5 . Toxicology Letters

Interactions of herbicides 2,4-D and dinoseb with liver mitochondrial bioenergetics

Palmeira, C.M.; Moreno, A.J.; Madeira, V.M.C., 1994. Toxicology and Applied Pharmacology. 50 - 57. 1. 127. 1994. http://www.scopus.com/inward/record.url?eid=2-s2.0-0028146853&partnerID=MN8TOARS . 10.1006/taap.1994.1138 . Toxicology and Applied Pharmacology

Anodic behavior of someVinca alkaloids with cytostatic activity: Effect of pH

Brett, A. M. Oliveira; Grazina, M. M. M.; Macedo, T. R. A.; Raimundo, D., 1994. Electroanalysis. 57 - 61. 1. 6. 1994. http://dx.doi.org/10.1002/elan.1140060111 . 10.1002/elan.1140060111 . published Electroanalysis

Metabolic alterations in hepatocytes promoted by the herbicides paraquat, dinoseb and 2,4-D

Palmeira, C.M.; Moreno, A.J.; Madeira, V.M.C., 1994. Archives of Toxicology. 24 - 31. 1. 68. 1994. http://www.scopus.com/inward/record.url?eid=2-s2.0-0028009773&partnerID=MN8TOARS . 10.1007/s002040050025 . Archives of Toxicology

A study of the electrochemical oxidation of Navelbine.

Brett AM; Grazina MM; Macedo TR; Oliveira C; Raimundo D; Brett, A.M.O.; Grazina, M.M.M.; et al, 1993. Journal of Pharmaceutical and Biomedical Analysis. 203 - 206. 3. 11. 1993. http://europepmc.org/abstract/med/8518318 . 10.1016/0731-7085(93)80197-9 . Journal of Pharmaceutical and Biomedical Analysis

Linkage and association study of the Dopamine D4 receptor gene and Psychosis

Petronis, A; Grazina, Manuela; Vicente, A.C.; Pato, CN; Azevedo, MHP; Meltzer, HY; Lieberman, JA; et al, 1993. Psychiatric Genetics. 155 - 156. 3. 1993. published Psychiatric Genetics

Dopaminergic system in Mexican schizophrenics

Nicoli, H; Sidenberg, D; Camarena, B; Guerra, C; Grazina, Manuela; Petronis, A; Kennedy, JL, 1993. Rev. Inv. Clin. 345 - 352. 45. 4. 1993. published Rev. Inv. Clin

Electrochemical study of a group of anticancer drugs

Ana Maria Oliveira Brett; Grazina, Manuela; Macedo, T.R.A.; Raimundo, D., 1993. Portugaliae Electrochimica Acta. 129 - 132. 11. 1993. published Portugaliae Electrochimica Acta

Membrane lipid peroxidation induces changes in ¿-[3H]aminobutyric acid transport and calcium uptake by synaptosomes

Palmeira, C.M.; Santos, M.S.; Carvalho, A.P.; Oliveira, C.R.; Palmeira CM; Santos MS; Carvalho AP; Oliveira CR, 1993. Brain Research. 117 - 123. 1-2. 609. 1993. http://www.scopus.com/inward/record.url?eid=2-s2.0-0027309463&partnerID=MN8TOARS . 10.1016/0006-8993(93)90863-I . Brain Research

Partitioning and membrane disordering effects of dopamine antagonists: Influence of lipid peroxidation, temperature, and drug concentration

Palmeira, C.M.; Oliveira, C.R., 1992. Archives of Biochemistry and Biophysics. 161 - 171. 1. 295. 1992. http://www.scopus.com/inward/record.url?eid=2-s2.0-0026729101&partnerID=MN8TOARS . 10.1016/0003-9861(92)90502-N . Archives of Biochemistry and Biophysics

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