Affiliation

1- CNC-Center for Neuroscience and Cell Biology, CIBB - Centre for Innovative Biomedicine and Biotechnology, University of Coimbra, (3004-504) Coimbra, Portugal; 2- IIIUC - Institute for Interdisciplinary Research, University of Coimbra, (3030-789) Coimbra, Portugal

Publications

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Information about journal articles, updated at 17-12-2023, from platform CIÊNCIAVITAE.

Mitochondrial Damage-Associated Molecular Patterns Content in Extracellular Vesicles Promotes Early Inflammation in Neurodegenerative Disorders

Cláudia Deus; Deus, CM; Henrique Tavares; Margarida Beatriz; Sandra Mota; C Lopes, Cells. 2364 - 2364. 15. 11. 2022. http://dx.doi.org/10.3390/cells11152364 . 10.3390/cells11152364 . Cells

Mitochondrial function and dynamics in neural stem cells and neurogenesis: Implications for neurodegenerative diseases.

Coelho P; Fão L; Mota S; Rego AC, Ageing research reviews. 2022. http://europepmc.org/abstract/med/35714855 . 10.1016/j.arr.2022.101667 . Ageing research reviews

Restoration of c-Src/Fyn proteins rescues mitochondrial dysfunction in Huntington's Disease.

Fão L; Coelho P; Duarte L; Vilaça R; Hayden M; Mota S; Rego AC, Antioxidants & redox signaling. 2022. http://europepmc.org/abstract/med/35651273 . 10.1089/ars.2022.0001 . Antioxidants & redox signaling

Mitochondrial and redox modifications in early stages of Huntington’s disease

Carla Maria Nunes Lopes; Ferreira, Ildete L.; Maranga, Carina; Beatriz, Margarida; de rosa maura; Sereno, José Vitor Oliveira; Castelo-Branco, Miguel; et al, redox modifications in early stages of Huntington’s disease”. Preprint . 2022. submitted redox modifications in early stages of Huntington’s disease”. Preprint

Neuroprotection of retinal ganglion cells by the sigma-1 receptor agonist pridopidine in models of experimental glaucoma.

Geva M; Gershoni-Emek N; Naia L; Ly P; Mota S; Rego AC; Hayden MR; Levin LA, Scientific reports. 2021. http://europepmc.org/abstract/med/34753986 . 10.1038/s41598-021-01077-w . Scientific reports

Mechanistic perspectives on differential mitochondrial-based neuroprotective effects of several carnitine forms in Alzheimer’s disease in vitro model

Sandra I. Mota; Inês Pita; Rodolfo Águas; Slah Tagorti; Ashraf Virmani; Frederico C. Pereira; A. Cristina Rego, Archives of Toxicology. 2769 - 2784. 8. 95. 2021. https://doi.org/10.1007/s00204-021-03104-1 . 10.1007/s00204-021-03104-1 . Archives of Toxicology

The Sigma-1 Receptor Mediates Pridopidine Rescue of Mitochondrial Function in Huntington Disease Models.

Mota, S.I.; Naia Luana; Philip Ly; Carla Maria Nunes Lopes; Maranga, Carina; Patrícia Coelho; Noga Gershoni-Emek; et al, Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics. 2021. https://doi.org/10.1007/s13311-021-01022-9 . 10.1007/s13311-021-01022-9 . accepted Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics

Chronic hyperglycemia impairs hippocampal neurogenesis and memory in an Alzheimer’s disease mouse model

Ferreiro, Elisabete; Lanzillo, Mariagrazia; Canhoto, Diogo; Carvalho da Silva, António M.; Mota, Sandra I.; Dias, Inês S.; Ferreira, Ildete L.; et al, Neurobiology of Aging. 98 - 113. 92. 2020. http://dx.doi.org/10.1016/j.neurobiolaging.2020.04.003 . 10.1016/j.neurobiolaging.2020.04.003 . Neurobiology of Aging

Shaping the Nrf2-ARE-related pathways in Alzheimer's and Parkinson's diseases.

Fão, Lígia; Mota, Sandra; Rego, Ana Cristina, Ageing research reviews. 2019. http://europepmc.org/abstract/med/31415806 . 10.1016/j.arr.2019.100942 . Ageing research reviews

c-Src regulates Nrf2 activity through PKCd after oxidant stimulus

Fão, Lígia*; Mota, Sandra I.*; Rego, A. Cristina, Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 686 - 698. 4. 1866. 2019. http://dx.doi.org/10.1016/j.bbamcr.2019.01.011 . 10.1016/j.bbamcr.2019.01.011 . Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

Coriolus versicolor biomass increases dendritic arborization of newly-generated neurons in mouse hippocampal dentate gyrus.

Ferreiro E; Pita IR; Mota SI; Valero J; Ferreira NR; Fernandes T; Calabrese V; et al, Oncotarget. 2018. http://europepmc.org/abstract/med/30250640 . 10.18632/oncotarget.25978 . Oncotarget

Oxidative stress involving changes in Nrf2 and ER stress in early stages of Alzheimer's disease

Mota, S.I.; Costa, R.O.; Ferreira, I.L.; Santana, I.; Caldeira, G.L.; Padovano, C.; Fonseca, A.C.; et al, Biochimica et Biophysica Acta - Molecular Basis of Disease. 1428 - 1441. 7. 1852. 2015. http://www.scopus.com/inward/record.url?eid=2-s2.0-84928128412&partnerID=MN8TOARS . 10.1016/j.bbadis.2015.03.015 . Biochimica et Biophysica Acta - Molecular Basis of Disease

Dysfunctional synapse in Alzheimer's disease - A focus on NMDA receptors

Mota, S.I.; Ferreira, I.L.; Rego, A.C., Neuropharmacology. 16 - 26. PART A. 76. 2014. http://www.scopus.com/inward/record.url?eid=2-s2.0-84886641553&partnerID=MN8TOARS . 10.1016/j.neuropharm.2013.08.013 . Neuropharmacology

Impaired Src signaling and post-synaptic actin polymerization in Alzheimer's disease mice hippocampus - Linking NMDA receptors and the reelin pathway

Mota, S.I.; Ferreira, I.L.; Valero, J.; Ferreiro, E.; Carvalho, A.L.; Oliveira, C.R.; Rego, A.C.; et al, Experimental Neurology. 698 - 709. 261. 2014. http://www.scopus.com/inward/record.url?eid=2-s2.0-84908339906&partnerID=MN8TOARS . 10.1016/j.expneurol.2014.07.023 . Experimental Neurology

Amyloid-beta peptide 1-42 causes microtubule deregulation through N-methyl-D-aspartate receptors in mature hippocampal cultures

Mota, S.I.; Ferreira, I.L.; Pereira, C.; Oliveira, C.R.; Rego, A.C., Current Alzheimer Research. 844 - 856. 7. 9. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84866468436&partnerID=MN8TOARS . 10.2174/156720512802455322 . Current Alzheimer Research

Amyloid beta peptide 1-42 disturbs intracellular calcium homeostasis through activation of GluN2B-containing N-methyl-d-aspartate receptors in cortical cultures

Ferreira, I.L.; Bajouco, L.M.; Mota, S.I.; Auberson, Y.P.; Oliveira, C.R.; Rego, A.C., Cell Calcium. 95 - 106. 2. 51. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84856958510&partnerID=MN8TOARS . 10.1016/j.ceca.2011.11.008 . Cell Calcium

Nedd9/Hef1/Cas-L mediates the effects of environmental pollutants on cell migration and plasticity

Bui, L.-C.; Tomkiewicz, C.; Chevallier, A.; Pierre, S.; Bats, A.-S.; Mota, S.; Raingeaud, J.; et al, Oncogene. 3642 - 3651. 41. 28. 2009. http://www.scopus.com/inward/record.url?eid=2-s2.0-70350066363&partnerID=MN8TOARS . 10.1038/onc.2009.224 . Oncogene

All projects

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Information of exclusive responsibility of the researcher 17-12-2023 , from platform CIÊNCIAVITAE.

2022/01/15 - 2025/01/14

Human Neuronal Cells Differentiated from Urine-derived Stem Cells as a Platform for Personalized Medicine in Amyotrophic Lateral Sclerosis

PTDC/BTM-ORG/0055/2021

Researcher

Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: Fundação para a Ciência e a Tecnologia

2021/01/01 -

Projeto Estratégico Centro de Inovação em Biomedicina e Biotecnologia

UIDP/04539/2020

Researcher

Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: Fundação para a Ciência e a Tecnologia

2021/01 -

Projeto Estratégico Centro de Inovação em Biomedicina e Biotecnologia

UIDB/04539/2020

Researcher

Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: Fundação para a Ciência e a Tecnologia

2021/10/01 -

Organelle-targeted Radiocomplexes for Auger Therapy of Cancer Radiocomplexos Dirigidos a Organelos Celulares para Terapia Auger do Cancro

PTDC/MED-QUI/1554/2020

Researcher

Universidade de Lisboa Instituto Superior Tecnico Campus Tecnológico e Nuclear

Funders: Fundação para a Ciência e a Tecnologia

2018/01/01 - 2018/05

Exploring the role of pridopidine on mitochondrial function and dynamics in Huntington’s disease models

N/A

Post-doc Fellow

Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: TEVA pharmaceuticals industries ltd.

2018/07 - 2021/03/31

Transcriptional activity modulation in Alzheimer's disease by inhibitors of histone deacetylases

POCI-01-0145-FEDER-032316

Researcher

Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: Fundação para a Ciência e a Tecnologia

2017 - 2017/09

Supplementation of Coriolus versicolor (biomass) - a nutritional presymptomatic approach against cognitive deficits

N/A

Post-doc Fellow

Funders: Mycology Research Laboratories (MRL) Ltd.

2014 - 2019

H2O2-mediated Src signaling pathways in glutamatergic synapses in Alzheimer's disease models

SFRH/BPD/99219/2013

Post-doc Fellow

Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: Fundação para a Ciência e a Tecnologia

2014/01 - 2016/02

Evaluation of oxidative stress and mitochondrial dysfunction in animal models and patients of Huntington’s disease using Cu(II)-ATSM PET

N/A

Post-doc Fellow

Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: Santa Casa da Misericórdia de Lisboa

2011/10 - 2014/12

Genetic susceptibility of multisystemic complications of diabetes type 2: novel biomarkers for diagnosis and monitoring of therapy

Do-IT “DIAMARKER PROJECT”

PhD Student Fellow

Universidade de Coimbra Faculdade de Medicina

Funders: Quadro de referência Estratégica Nacional

2009/01/01 - 2012/12/31

NMDA receptors-associated events and oxidative stress in models of Alzheimer’s disease

SFRH/BD/43430/2008

Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: Fundação para a Ciência e a Tecnologia

2009/03 - 2011/02

Phosphorylation and oxidation of NMDA receptor subunits in Alzheimer’s disease and protective role of memantine

N/A

PhD Student Fellow

Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: H. Lundbeck A/S

2009/03 - 2011/02

Phosphorylation and oxidation of NMDA receptor subunits in Alzheimer’s disease and protective role of memantine

N/A

PhD Student Fellow

Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: H. Lundbeck A/S

2008/09/01 - 2010/12

Contribution of N-methyl-D-aspartate receptors subunits to neuronal dysfunction in Alzheimer’s disease

PTDC/SAU-NEU/71675/2006

PhD Student Fellow

Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: Fundação para a Ciência e a Tecnologia

2007/10/01 - 2008/08/31

Polluants Organiques persistants (POP)_ Migration cellulaire et progression tumorale – ONCOPOP

ANR-02-ESTE-0026

Master Student Fellow

INSERM Délégation Régionale Paris 5

Funders: Agence nationale de la recherche

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