Publications
Information about journal articles, updated at 21-07-2024, from platform CIÊNCIAVITAE.
Drinking water microbiota, entero-mammary pathways, and breast cancer: focus on nontuberculous mycobacteria
Maranha A, Microorganisms. 12. 2024. published Microorganisms
The Gut-Brain Axis in Alzheimer’s and Parkinson’s Diseases: The Catalytic Role of Mitochondria
Candeias E, Journal of Alzheimer's Disease. 1 - 17. 2024. http://dx.doi.org/10.3233/jad-240524 . 10.3233/jad-240524 . published Journal of Alzheimer's Disease
Neuronal control of microglia through the mitochondria
Pereira-Santos AR, Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 2024. http://dx.doi.org/10.1016/j.bbadis.2024.167167 . 10.1016/j.bbadis.2024.167167 . published Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
Nocardia cyriacigeorgica elicits gut disturbances in a leaky gut model of colitis, but not the harmful cascade leading to gut-first Parkinson’s Disease
Magalhães JD, International Journal of Molecular Sciences. 2024. https://doi.org/10.3390/ijms25063423 . published International Journal of Molecular Sciences
Gut-brain-axis impact on canine anxiety disorders: new challenges for behavioral veterinary medicine
Sacoor C, Veterinary Medicine International. 2856759. 2024. 2024. https://doi.org/10.1155/2024/2856759 . published Veterinary Medicine International
Effect of ScCO2 on the decontamination of PECs-based cryogels: a comparison with H2O steam and H2O2 nebulization methods
Bento CSA, International Journal of Pharmaceutics. 2023. http://dx.doi.org/10.1016/j.ijpharm.2023.123451 . 10.1016/j.ijpharm.2023.123451 . published International Journal of Pharmaceutics
Sustainable starch-based edible films with agrifood residues as potential carriers for the probiotic Lactobacillus rhamnosus
Coimbra P, Innovative Food Science & Emerging Technologies. 88. 2023. http://dx.doi.org/10.1016/j.ifset.2023.103452 . 10.1016/j.ifset.2023.103452 . published Innovative Food Science & Emerging Technologies
Intestinal infection triggers mitochondria-mediated a-synuclein pathology: relevance to Parkinsons disease
Magalhães JD, Cellular and Molecular Life Sciences. 6. 80. 2023. http://dx.doi.org/10.1007/s00018-023-04819-3 . 10.1007/s00018-023-04819-3 . published Cellular and Molecular Life Sciences
The role of bacteria-mitochondria communication in the activation of neuronal innate immunity: Implications to Parkinson's Disease
Magalhães JD, International Journal of Molecular Sciences. 5. 24. 2023. http://dx.doi.org/10.3390/ijms24054339 . 10.3390/ijms24054339 . published International Journal of Molecular Sciences
Footprints of a microbial toxin from the gut microbiome to mesencephalic mitochondria
Esteves AR; Alarico S, Gut. 73 - 89. 1. 72. 2023. http://dx.doi.org/10.1136/gutjnl-2021-326023 . 10.1136/gutjnl-2021-326023 . published Gut
Self-recycling and partially conservative replication of mycobacterial methylmannose polysaccharides
Maranha A; Pereira PJB, Empadinhas N, Communications Biology. 1. 6. 2023. https://doi.org/10.1038/s42003-023-04448-3 . 10.1038/s42003-023-04448-3 . published Communications Biology
Parkinson's Disease: A Multisystem Disorder
Costa HN, Neuroscience Bulletin. 113 - 124. 1. 39. 2023. http://dx.doi.org/10.1007/s12264-022-00934-6 . 10.1007/s12264-022-00934-6 . published Neuroscience Bulletin
Sequential scCO2 drying and sterilisation of alginate-gelatine aerogels for biomedical applications
Bento C, The Journal of Supercritical Fluids. 184. 2022. http://dx.doi.org/10.1016/j.supflu.2022.105570 . 10.1016/j.supflu.2022.105570 . published The Journal of Supercritical Fluids
Enzyme promiscuity in serotonin biosynthesis, from bacteria to plants and humans
Gonçalves S, Frontiers in Microbiology. 13. 2022. http://dx.doi.org/10.3389/fmicb.2022.873555 . 10.3389/fmicb.2022.873555 . published Frontiers in Microbiology
Neurodegenerative Microbially-Shaped Diseases: Oxidative Stress Meets Neuroinflammation
Silva DF, Antioxidants. 11. 11. 2022. http://dx.doi.org/10.3390/antiox11112141 . 10.3390/antiox11112141 . published Antioxidants
The neuromicrobiology of Parkinson's disease: A unifying theory
Muñoz-Pinto MF, Ageing Research Reviews. 70. 2021. http://dx.doi.org/10.1016/j.arr.2021.101396 . 10.1016/j.arr.2021.101396 . published Ageing Research Reviews
Improved diabetic wound healing by bovine lactoferricin is associated with relevant changes in the skin immune response and microbiota
Mouritzen MV, Molecular Therapy - Methods & Clinical Development. 726 - 739. 20. 2021. https://doi.org/10.1016/j.omtm.2021.02.008 . 10.1016/j.omtm.2021.02.008 . published Molecular Therapy - Methods & Clinical Development
The Mitochondrial Ribosome: A World of Opportunities for Mitochondrial Dysfunction Toward Parkinson's Disease
Gonçalves AM, Antioxidants & Redox Signaling. 694 - 711. 8. 34. 2021. https://www.liebertpub.com/doi/10.1089/ars.2019.7997 . 10.1089/ars.2019.7997 . published Antioxidants & Redox Signaling
Microbial BMAA elicits mitochondrial dysfunction, innate immunity activation and Alzheimer's disease features in cortical neurons
Silva DF, Journal of Neuroinflammation. 332. 17. 2020. http://dx.doi.org/10.1186/s12974-020-02004-y . 10.1186/s12974-020-02004-y . published Journal of Neuroinflammation
Editorial: Interplay Between Nutrition, the Intestinal Microbiota and the Immune System
Oriá RB, Frontiers in Immunology. 11. 2020. http://dx.doi.org/10.3389/fimmu.2020.01758 . 10.3389/fimmu.2020.01758 . published Frontiers in Immunology
Stabilization of blood for long-term storage can affect antibody-based recognition of cell surface markers
Silva MB; Färnert A, Journal of Immunological Methods. 481. 2020. http://dx.doi.org/10.1016/j.jim.2020.112792 . 10.1016/j.jim.2020.112792 . published Journal of Immunological Methods
A genuine mycobacterial thermophile: Mycobacterium hassiacum growth, survival and GpgS stability at near-pasteurization temperatures
Alarico S, Microbiology. 474 - 483. 5. 166. 2020. http://dx.doi.org/10.1099/mic.0.000898 . 10.1099/mic.0.000898 . published Microbiology
Microbial BMAA and the Pathway for Parkinson's Disease Neurodegeneration
Nunes-Costa D, Frontiers in Aging Neuroscience. 12. 2020. https://doi.org/10.3389/fnagi.2020.00026 . 10.3389/fnagi.2020.00026 . published Frontiers in Aging Neuroscience
The structural characterization of a glucosylglycerate hydrolase provides insights into the molecular mechanism of mycobacterial recovery from nitrogen starvation
Cereija TB, IUCrJ. 572 - 585. 4. 6. 2019. https://doi.org/10.1107/S2052252519005372 . 10.1107/S2052252519005372 . published IUCrJ
High-Quality Draft Genome Sequences of Rare Nontuberculous Mycobacteria Isolated from Surfaces of a Hospital
Tiago I, Microbiology Resource Announcements. 21. 8. 2019. https://doi.org/10.1128/MRA.00496-19 . 10.1128/MRA.00496-19 . published Microbiology Resource Announcements
Biosynthesis of mycobacterial methylmannose polysaccharides requires a unique 1-O-methyltransferase specific for 3-O-methylated mannosides
Ripoll-Rozada J; Pereira PJB; Empadinhas N, Proceedings of the National Academy of Sciences. 201813450 - 201813450. 2019. https://www.pnas.org/content/116/3/835.long . 10.1073/pnas.1813450116 . published Proceedings of the National Academy of Sciences
Studies of antimicrobial resistance in rare mycobacteria from a nosocomial environment
Pereira SG, BMC Microbiology. 1. 19. 2019. http://dx.doi.org/10.1186/s12866-019-1428-4 . 10.1186/s12866-019-1428-4 . published BMC Microbiology
Molecular Fingerprints for a Novel Enzyme Family in Actinobacteria with Glucosamine Kinase Activity
Manso JA, mBio. 2019. https://doi.org/10.1128/mBio.00239-19 . 10.1128/mBio.00239-19 . published mBio
The Microbiome-Mitochondria Dance in Prodromal Parkinson's Disease
Cardoso SM, Empadinhas N, Frontiers in Physiology. 9. 2018. https://www.frontiersin.org/articles/10.3389/fphys.2018.00471/full . 10.3389/fphys.2018.00471 . published Frontiers in Physiology
Production, crystallization and structure determination of a mycobacterial glucosylglycerate hydrolase
Cereija TB, Acta Crystallographica Section F Structural Biology Communications. 536 - 540. 9. 73. 2017. https://doi.org/10.1107%2Fs2053230x17012419 . 10.1107/S2053230X17012419 . published Acta Crystallographica Section F Structural Biology Communications
Hospital microbial surface colonization revealed during monitoring of Klebsiella spp., Pseudomonas aeruginosa, and non-tuberculous mycobacteria
Farias PG, Antonie van Leeuwenhoek. 863 - 876. 7. 110. 2017. http://dx.doi.org/10.1007/s10482-017-0857-z . 10.1007/s10482-017-0857-z . published Antonie van Leeuwenhoek
Microbiota of Chronic Diabetic Wounds: Ecology, Impact, and Potential for Innovative Treatment Strategies
Pereira SG, Frontiers in Microbiology. 8. 2017. https://doi.org/10.3389%2Ffmicb.2017.01791 . 10.3389/fmicb.2017.01791 . published Frontiers in Microbiology
Glucosylglycerate metabolism, bioversatility and mycobacterial survival
Nunes-Costa D, Glycobiology. 213 - 227. 27. 2016. http://dx.doi.org/10.1093/glycob/cww132 . 10.1093/glycob/cww132 . published Glycobiology
The looming tide of nontuberculous mycobacterial infections in Portugal and Brazil
Nunes-Costa D, Tuberculosis. 107 - 119. 96. 2016. http://dx.doi.org/10.1016/j.tube.2015.09.006 . 10.1016/j.tube.2015.09.006 . published Tuberculosis
Octanoylation of early intermediates of mycobacterial methylglucose lipopolysaccharides
Maranha A; Clarke AJ, Empadinhas N, Scientific Reports. 1. 5. 2015. http://dx.doi.org/10.1038/srep13610 . 10.1038/srep13610 . published Scientific Reports
Structure of mycobacterial maltokinase, the missing link in the essential GlgE-pathway
Fraga JS, Scientific Reports. 5. 2015. https://doi.org/10.1038/srep08026 . 10.1038/srep08026 . published Scientific Reports
Structure of Mycobacterium thermoresistibile GlgE defines novel conformational states that contribute to the catalytic mechanism
Mendes V, Scientific Reports. 1. 5. 2015. http://dx.doi.org/10.1038/srep17144 . 10.1038/srep17144 . published Scientific Reports
The molecular biology of mycobacterial trehalose in the quest for advanced tuberculosis therapies
Nobre A, Microbiology (United Kingdom). 1547 - 1570. PART 8. 160. 2014. https://doi.org/10.1099/mic.0.075895-0 . 10.1099/mic.0.075895-0 . published Microbiology (United Kingdom)
Mycobacterium hassiacum recovers from nitrogen starvation with up-regulation of a novel glucosylglycerate hydrolase and depletion of the accumulated glucosylglycerate
Alarico S, Scientific Reports. 1. 4. 2014. http://dx.doi.org/10.1038/srep06766 . 10.1038/srep06766 . published Scientific Reports
Autophagy in the fight against tuberculosis
Bento CF, DNA and Cell Biology. 228 - 242. 4. 34. 2014. https://doi.org/10.1089/dna.2014.2745 . 10.1089/dna.2014.2745 . published DNA and Cell Biology
The plant Selaginella moellendorffii possesses enzymes for synthesis and hydrolysis of the compatible solutes mannosylglycerate and glucosylglycerate
Nobre A, Planta. 891 - 901. 3. 237. 2013. https://doi.org/10.1007/s00425-012-1808-6 . 10.1007/s00425-012-1808-6 . published Planta
A new bacterial hydrolase specific for the compatible solutes alpha-D-mannopyranosyl-(1,2)-D-glycerate and alpha-D-glucopyranosyl-(1,2)-D-glycerate
Alarico S, Enzyme and Microbial Technology. 77 - 83. 2. 52. 2013. http://dx.doi.org/10.1016/j.enzmictec.2012.10.008 . 10.1016/j.enzmictec.2012.10.008 . published Enzyme and Microbial Technology
Genome sequence of Mycobacterium hassiacum DSM 44199, a rare source of heat-stable mycobacterial proteins
Tiago I, Journal of Bacteriology. 7010 - 7011. 24. 194. 2012. DOI: https://doi.org/10.1128/JB.01880-12 . 10.1128/JB.01880-12 . published Journal of Bacteriology
Biosynthesis of mycobacterial methylglucose lipopolysaccharides
Mendes V, Natural Product Reports. 834 - 844. 8. 29. 2012. https://doi.org/10.1039/C2NP20014G . 10.1039/c2np20014g . published Natural Product Reports
Mycobacterium tuberculosis Rv2419c, the missing glucosyl-3-phosphoglycerate phosphatase for the second step in methylglucose lipopolysaccharide biosynthesis
Mendes V, Scientific Reports. 1. 1. 2011. http://dx.doi.org/10.1038/srep00177 . 10.1038/srep00177 . published Scientific Reports
Functional and structural characterization of a novel mannosyl-3-phosphoglycerate synthase from Rubrobacter xylanophilus reveals its dual substrate specificity
Empadinhas N, Molecular Microbiology. 76 - 93. 1. 79. 2011. https://doi.org/10.1111/j.1365-2958.2010.07432.x . 10.1111/j.1365-2958.2010.07432.x . published Molecular Microbiology
Diversity, biological roles and biosynthetic pathways for sugar-glycerate containing compatible solutes in bacteria and archaea
Empadinhas N, da Costa MS, Environmental Microbiology. 2056 - 2077. 8. 13. 2011. https://doi.org/10.1111/j.1462-2920.2010.02390.x . 10.1111/j.1462-2920.2010.02390.x . published Environmental Microbiology
Two alternative pathways for the synthesis of the rare compatible solute mannosylglucosylglycerate in Petrotoga mobilis
Fernandes C, Journal of Bacteriology. 1624 - 1633. 6. 192. 2010. https://doi.org/10.1128/JB.01424-09 . 10.1128/JB.01424-09 . published Journal of Bacteriology
Biochemical characterization of the maltokinase from Mycobacterium bovis BCG
Mendes V, BMC Biochemistry. 2010. https://doi.org/10.1186/1471-2091-11-21 . 10.1186/1471-2091-11-21 . published BMC Biochemistry
Identification of the mycobacterial glucosyl-3-phosphoglycerate synthase
Empadinhas N, FEMS Microbiology Letters. 195 - 202. 2. 280. 2008. https://doi.org/10.1111/j.1574-6968.2007.01064.x . 10.1111/j.1574-6968.2007.01064.x . published FEMS Microbiology Letters
Crystallization and preliminary crystallographic analysis of mannosyl-3-phosphoglycerate synthase from Rubrobacter xylanophilus
Sá-Moura B, Acta Crystallographica Section F: Structural Biology and Crystallization Communications. 760 - 763. 8. 64. 2008. https://doi.org/10.1107/S1744309108021490 . 10.1107/S1744309108021490 . published Acta Crystallographica Section F: Structural Biology and Crystallization Communications
To be or not to be a compatible solute: Bioversatility of mannosylglycerate and glucosylglycerate
Empadinhas N, da Costa MS, Systematic and Applied Microbiology. 159 - 168. 3. 31. 2008. https://doi.org/10.1016/j.syapm.2008.05.002 . 10.1016/j.syapm.2008.05.002 . published Systematic and Applied Microbiology
Osmoadaptation mechanisms in prokaryotes: Distribution of compatible solutes
Empadinhas N, da Costa MS, International Microbiology. 151 - 161. 3. 11. 2008. https://europepmc.org/article/med/18843593 . 10.2436/20.1501.01.55 . published International Microbiology
Mycobacterium tuberculosis glucosyl-3-phosphoglycerate synthase: Structure of a key enzyme in methylglucose lipopolysaccharide biosynthesis
Pereira PJB, PLoS ONE. 11. 3. 2008. https://doi.org/10.1371/journal.pone.0003748 . 10.1371/journal.pone.0003748 . published PLoS ONE
Molecular and physiological role of the trehalose-hydrolyzing a-glucosidase from Thermus thermophilus HB27
Alarico S, Journal of Bacteriology. 2298 - 2305. 7. 190. 2008. http://www.scopus.com/inward/record.url?eid=2-s2.0-41549086172&partnerID=MN8TOARS . 10.1128/JB.01794-07 . published Journal of Bacteriology
A Unique Combination of Genetic Systems for the Synthesis of Trehalose in Rubrobacter xylanophilus: Properties of a Rare Actinobacterial TreT
Nobre A, Journal of Bacteriology. 7939 - 7946. 24. 190. 2008. http://dx.doi.org/10.1128/jb.01055-08 . 10.1128/jb.01055-08 . published Journal of Bacteriology
Single-step pathway for synthesis of glucosylglycerate in Persephonella marina
Fernandes C, Journal of Bacteriology. 4014 - 4019. 11. 189. 2007. http://www.scopus.com/inward/record.url?eid=2-s2.0-34249786874&partnerID=MN8TOARS . 10.1128/JB.00075-07 . published Journal of Bacteriology
Organic solutes in Rubrobacter xylanophilus: The first example of di-myo-inositol-phosphate in a thermophile
Empadinhas N, Extremophiles. 667 - 673. 5. 11. 2007. http://www.scopus.com/inward/record.url?eid=2-s2.0-34548303944&partnerID=MN8TOARS . 10.1007/s00792-007-0084-z . published Extremophiles
Mannosylglycerate is essential for osmotic adjustment in Thermus thermophilus strains HB27 and RQ-1
Alarico S, Extremophiles. 833 - 840. 6. 11. 2007. http://www.scopus.com/inward/record.url?eid=2-s2.0-35748948644&partnerID=MN8TOARS . 10.1007/s00792-007-0106-x . published Extremophiles
Glucosylglycerate biosynthesis in the deepest lineage of the Bacteria: Characterization of the thermophilic proteins GpgS and GpgP from Persephonella marina
Costa J, Journal of Bacteriology. 1648 - 1654. 5. 189. 2007. http://www.scopus.com/inward/record.url?eid=2-s2.0-33947366922&partnerID=MN8TOARS . 10.1128/JB.00841-06 . published Journal of Bacteriology
Bifunctional CTP:inositol-1-phosphate cytidylyltransferase/CDP-inositol: Inositol-1-phosphate transferase, the key enzyme for di-myo-inositol-phosphate synthesis in several (hyper)thermophiles
Rodrigues MV, Journal of Bacteriology. 5405 - 5412. 15. 189. 2007. http://www.scopus.com/inward/record.url?eid=2-s2.0-34547629796&partnerID=MN8TOARS . 10.1128/JB.00465-07 . published Journal of Bacteriology
Characterization of the biosynthetic pathway of glucosylglycerate in the archaeon Methanococcoides burtonii
Costa J, Journal of Bacteriology. 1022 - 1030. 3. 188. 2006. http://www.scopus.com/inward/record.url?eid=2-s2.0-31344453995&partnerID=MN8TOARS . 10.1128/JB.188.3.1022-1030.2006 . published Journal of Bacteriology
Diversity and biosynthesis of compatible solutes in hyper/thermophiles
Empadinhas N, da Costa MS, International Microbiology. 199 - 206. 3. 9. 2006. http://www.scopus.com/inward/record.url?eid=2-s2.0-33750584278&partnerID=MN8TOARS . published International Microbiology
Distribution of genes for synthesis of trehalose and mannosylglycerate in Thermus spp. and direct correlation of these genes with halotolerance
Alarico S, Applied and Environmental Microbiology. 2460 - 2466. 5. 71. 2005. http://www.scopus.com/inward/record.url?eid=2-s2.0-18444382346&partnerID=MN8TOARS . 10.1128/AEM.71.5.2460-2466.2005 . published Applied and Environmental Microbiology
Meiothermus timidus sp. nov., a new slightly thermophilic yellow-pigmented species
Pires AL, FEMS Microbiology Letters. 39 - 45. 1. 245. 2005. http://www.scopus.com/inward/record.url?eid=2-s2.0-15744405109&partnerID=MN8TOARS . 10.1016/j.femsle.2005.02.011 . published FEMS Microbiology Letters
Specialized Roles of the Two Pathways for the Synthesis of Mannosylglycerate in Osmoadaptation and Thermoadaptation of Rhodothermus marinus
Borges N, Journal of Biological Chemistry. 9892 - 9898. 11. 279. 2004. http://www.scopus.com/inward/record.url?eid=2-s2.0-1642279326&partnerID=MN8TOARS . 10.1074/jbc.M312186200 . published Journal of Biological Chemistry
A gene from the mesophilic bacterium Dehalococcoides ethenogenes encodes a novel mannosylglycerate synthase
Empadinhas N, Journal of Bacteriology. 4075 - 4084. 13. 186. 2004. http://www.scopus.com/inward/record.url?eid=2-s2.0-3042523198&partnerID=MN8TOARS . 10.1128/JB.186.13.4075-4084.2004 . published Journal of Bacteriology
The Bacterium Thermus thermophilus , Like Hyperthermophilic Archaea, Uses a Two-Step Pathway for the Synthesis of Mannosylglycerate
Empadinhas N, Applied and Environmental Microbiology. 3272 - 3279. 6. 69. 2003. http://dx.doi.org/10.1128/aem.69.6.3272-3279.2003 . 10.1128/aem.69.6.3272-3279.2003 . published Applied and Environmental Microbiology
Gamma-Proteobacteria Aquicella lusitana gen. nov., sp. nov., and Aquicella siphonis sp. nov. Infect Protozoa and Require Activated Charcoal for Growth in Laboratory Media
Santos P, Applied and Environmental Microbiology. 6533 - 6540. 11. 69. 2003. http://www.scopus.com/inward/record.url?eid=2-s2.0-0242573382&partnerID=MN8TOARS . 10.1128/AEM.69.11.6533-6540.2003 . published Applied and Environmental Microbiology
Rubritepida flocculans gen. nov., sp. nov., a New Slightly Thermophilic Member of the a-1 Subclass of the Proteobacteria
Alarico S, Systematic and Applied Microbiology. 198 - 206. 2. 25. 2002. http://dx.doi.org/10.1078/0723-2020-00116 . 10.1078/0723-2020-00116 . published Systematic and Applied Microbiology
Albidovulum inexpectatum gen. nov., sp. nov., a nonphotosynthetic and slightly thermophilic bacterium from a marine hot spring that is very closely related to members of the photosynthetic genus Rhodovulum
Albuquerque L, Applied and Environmental Microbiology. 4266 - 4273. 9. 68. 2002. http://www.scopus.com/inward/record.url?eid=2-s2.0-0036729238&partnerID=MN8TOARS . 10.1128/AEM.68.9.4266-4273.2002 . published Applied and Environmental Microbiology
Pathway for the synthesis of mannosylglycerate in the hyperthermophilic archaeon Pyrococcus horikoshii: Biochemical and genetic characterization of key enzymes
Empadinhas N, Journal of Biological Chemistry. 43580 - 43588. 47. 276. 2001. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035941355&partnerID=MN8TOARS . 10.1074/jbc.M108054200 . published Journal of Biological Chemistry
Biosynthesis of mannosylglycerate in the thermophilic bacterium Rhodothermus marinus. Biochemical and genetic characterization of a mannosylglycerate synthase
Martins LO, Journal of Biological Chemistry. 35407 - 35414. 50. 274. 1999. http://www.scopus.com/inward/record.url?eid=2-s2.0-0033544948&partnerID=MN8TOARS . 10.1074/jbc.274.50.35407 . published Journal of Biological Chemistry
5 73 out of 73 Publications
All projects
Information of exclusive responsibility of the researcher 21-07-2024 , from platform CIÊNCIAVITAE.
2023 - 2026
Validation of bacterial-derived anti-inflammatory mediators in gut-first PD
CP code: SC01
Researcher
Universidade de Coimbra Centro de Inovação em Biomedicina e Biotecnologia; Universidade de Coimbra Centro de Neurociências e Biologia Celular
Funders: Cure Parkinson's
2023 - 2025
Exploring bacterial interactions to find novel molecules to combat the antimicrobial resistance catastrophe
2022.06809.PTDC
Researcher
Universidade de Coimbra Centro de Inovação em Biomedicina e Biotecnologia; Centro de Neurociências e Biologia Celular da Universidade de Coimbra
Funders: Fundação para a Ciência e a Tecnologia
2022 - 2025
Nontuberculous mycobacteria from drinking water: beyond the lung disease epidemic
PTDC/BIA-MIC/0122/2021
Principal investigator
Universidade de Coimbra Centro de Inovação em Biomedicina e Biotecnologia; Administração Regional de Saúde do Centro IP; Universidade do Porto Instituto de Saúde Pública
Funders: Fundação para a Ciência e a Tecnologia
2022 - 2023
Microbiome-miRNAs axis in Parkinsons disease: involvement of mitochondrial mediated inflammatory response
EXPL/MED-NEU/1515/2021
Researcher
Centro de Neurociências e Biologia Celular da Universidade de Coimbra; Universidade de Coimbra Centro de Inovação em Biomedicina e Biotecnologia
Funders: Fundação para a Ciência e a Tecnologia
2021 - 2025
DYNABrain - Dynamic Brain Function: Towards the Understanding and Treatment of Brain Disorders (ERA Chairs - Institutional)
H2020-WIDESPREAD-2018-2020-6, ID: 952422
Other
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Funders: European Commission
2021 - 2025
CIBB - Center for Innovative Biomedicine and Biotechnology - Associate Laboratory (Institutional)
LA/P/0058/2020
Researcher
Universidade de Coimbra Centro de Inovação em Biomedicina e Biotecnologia
Funders: Fundação para a Ciência e a Tecnologia
2021 - 2023
The Gut-Immune-Brain Axis in Parkinson disease
PTDC/MED-NEU/3644/2020
Co-Principal Investigator (Co-PI)
Universidade de Coimbra Centro de Neurociências e Biologia Celular; Universidade de Coimbra Centro de Inovação em Biomedicina e Biotecnologia
Funders: Fundação para a Ciência e a Tecnologia
2020 - 2021
Sustainable and dual function polymeric edible films: a probiotic and antioxidant delivery food packaging system
Prémio Projetos Semente de I&D "Era pós-COVID 19: uma sociedade mais sustentável, resiliente e justa
Researcher
Universidade de Coimbra
Funders: Universidade de Coimbra/Santander
2020 - 2023
CIBB - Center for Innovative Biomedicine and Biotechnology (Institutional)
UIDB/04539/2020 and UIDP/04539/2020
Researcher
Universidade de Coimbra Centro de Inovação em Biomedicina e Biotecnologia (CIBB)
Funders: Fundação para a Ciência e a Tecnologia
2018 - 2018
Prevalência de micobactérias não-tuberculosas em ambiente doméstico
Prémio Thomé Villar/Boehringer Ingelheim 2017
Co-Principal Investigator (Co-PI)
Universidade do Porto Instituto de Saúde Pública; Universidade de Coimbra Centro de Inovação em Biomedicina e Biotecnologia
Funders: Sociedade Portuguesa de Pneumologia; Boehringer Ingelheim Portugal
2018 - 2022
Green method to prepare sterilized biopolymers based aerogel
PTDC/EQU-EPQ/32625/2017
Researcher
Universidade de Coimbra; Universidade de Coimbra Centro de Neurociências e Biologia Celular; Universidade de Coimbra Centro de Inovação em Biomedicina e Biotecnologia
Funders: Fundação para a Ciência e a Tecnologia
2018/06/15 - 2021/12/31
An intriguing mycobacterial polysaccharide: recycling, replication and beyond
PTDC/BTM-TEC/29221/2017
Principal investigator
Universidade de Coimbra Centro de Neurociências e Biologia Celular; Universidade de Coimbra Centro de Inovação em Biomedicina e Biotecnologia; Universidade do Porto Instituto de Biologia Molecular e Celular; Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde
Funders: Fundação para a Ciência e a Tecnologia
2017 - 2021
HealthyAging2020 (WP9 - Deciphering microbiome signatures in chronic diseases for early diagnosis and modulation therapies) (Institutional-HR)
CENTRO-01-0145-FEDER-000012-N2323
Researcher
Universidade de Coimbra - Centro de Neurociências e Biologia Celular; CNC.IBILI
Funders: European Regional Development Fund; Comissão de Coordenação e Desenvolvimento Regional do Centro
2017 - 2020
The toxinogenic gut microbiome in sporadic Parkinson's Disease: a quest for "antiPDbiotics"
Mantero Belard Prize 2016 - MB-40-2016
Co-Principal Investigator (Co-PI)
Universidade de Coimbra Centro de Neurociências e Biologia Celular; Universidade de Coimbra Centro de Inovação em Biomedicina e Biotecnologia
Funders: Santa Casa da Misericórdia de Lisboa
2016 - 2016
The impairment of neuronal metabolism by gut microbiome effectors
FMUC-BST-2016-221
Researcher
Universidade de Coimbra Faculdade de Medicina
Funders: Faculdade de Medicina, Universidade de Coimbra & Banco Santander
2016 - 2018
Microcare - Microbiome of diabetic ulcers: early diagnosis, prognosis and therapy
FIS-2015-01_DIA_20150630-144
Co-Principal Investigator (Co-PI)
Universidade de Coimbra Centro de Neurociências e Biologia Celular; CNC.IBILI
Funders: Infarmed - Fundo para a Investigação em Saúde
2014 - 2015
Produção e comercialização global de compostos microbianos para investigação
InovC 2014
Principal investigator
Universidade de Coimbra
Funders: European Regional Development Fund
2013 - 2015
Ambiguity and virulence in a human pathogen
PTDC/BBB-BEP/0695/2012
Researcher
Instituto de Biologia Molecular e Celular; Centro de Neurociências e Biologia Celular da Universidade de Coimbra
Funders: Fundação para a Ciência e a Tecnologia
2013 - 2015
Biosynthesis of rare methylmannose polysaccharides in nontuberculous mycobacteria
PTDC/BIA-MIC/2779/2012
Principal investigator
Universidade de Coimbra Centro de Neurociências e Biologia Celular; Universidade do Porto Instituto de Biologia Molecular e Celular; Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica
Funders: Fundação para a Ciência e a Tecnologia
2012 - 2014
Unravelling the early steps in the biosynthesis of the mycobacterial MGLP
Grant 120123
Principal investigator
Universidade de Coimbra - Centro de Neurociências e Biologia Celular
Funders: Mizutani Foundation for Glycoscience
2011 - 2014
Pathway for the synthesis of the mycobacterial MGLP. Biochemical and structural characterization of the key enzymes
PTDC/BIA-PRO/110523/2009
Principal investigator
Centro de Neurociências e Biologia Celular da Universidade de Coimbra; Universidade do Porto Instituto de Biologia Molecular e Celular
Funders: Fundação para a Ciência e a Tecnologia
2011 - 2013
The enigmatic mycobacterial maltokinase
PTDC/BIA-BCM/112459/2009
Principal investigator
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Funders: Fundação para a Ciência e a Tecnologia
2009 - 2010
Characterization and evolution of a rare glycosyltransferase from the anti-tumor producing bacteria of the genus Actinosynnema (PI)
Acordo cultural 2010 Eslováquia 124626903612592
Principal investigator
Universidade de Coimbra Centro de Neurociências e Biologia Celular
2009 - 2010
Characterization and evolution of a rare glycosyltransferase from the antitumor producing bacteria of the genus Actinosynnema
Acordo Cultural 2010 Eslováquia 124626903612592
Principal investigator
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Funders: Fundação para a Ciência e a Tecnologia
2008 - 2010
Cloning, expression and regulation of genes for the synthesis of compatible solutes in Thermus thermophilus
Acção Nº E-9/08
Researcher
Universidade de Coimbra; Centro de Neurociências e Biologia Celular da Universidade de Coimbra
Funders: Conselho de Reitores das Universidades Portuguesas, Portugal
2005 - 2008
Nature´s shields to environmental stress. Biosynthesis of compatible solutes in extremely radiation-resistant Rubrobacter spp.
POCI/BIA-MIC/56511/2004
Researcher
Centro de Neurociências e Biologia Celular da Universidade de Coimbra; Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica
Funders: Fundação para a Ciência e a Tecnologia
2005 - 2008
Compatible solutes from extremophiles: screening, biosynthesis and heterologous production
POCI/V.5/A0005/2005
Researcher
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Funders: Fundação para a Ciência e a Tecnologia
2004 - 2006
Hotsolutes: New applications for compatible solutes from Extremophiles
COOP-CT-2003-508644
Post-doc Fellow
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica; Centro de Neurociências e Biologia Celular da Universidade de Coimbra
Funders: European Commission
2002 - 2004
Hypersolutes: Exploiting new solutes from hyperthermophiles for the preservation of biomaterials: cell factories for production of hypersolutes
QLK3-CT-2000-00640
PhD Student Fellow
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica; Universidade de Coimbra Centro de Neurociências e Biologia Celular
Funders: European Commission
2001 - 2004
Towards the Utilization of Cell-Reactors for the Production of Mannosylglycerate, an Enzyme Stabilizer from Hyperthermophiles
POCTI/BIO/35715/1999
PhD Student Fellow
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica
Funders: Fundação para a Ciência e a Tecnologia
1997 - 1999
Extremophiles as cell factories
BIO4960488
Master Student Fellow
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica
Funders: European Commission
5 31 out of 31 projects
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