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Information about journal articles, updated at 17-12-2023, from platform CIÊNCIAVITAE.

Nocardia cyriacigeorgica elicits gut disturbances in a leaky gut model of colitis, but not the harmful cascade leading to gut-first Parkinson’s Disease

Magalhães JD, 2024. https://doi.org/10.3390/ijms25063423 . published

Gut-brain-axis impact on canine anxiety disorders: new challenges for behavioral veterinary medicine

Sacoor C, Veterinary Medicine International. 2856759. 2024. 2024. https://doi.org/10.1155/2024/2856759 . published Veterinary Medicine International

Effect of ScCO2 on the decontamination of PECs-based cryogels: a comparison with H2O steam and H2O2 nebulization methods

Bento CSA, International Journal of Pharmaceutics. 2023. http://dx.doi.org/10.1016/j.ijpharm.2023.123451 . 10.1016/j.ijpharm.2023.123451 . published International Journal of Pharmaceutics

Sustainable starch-based edible films with agrifood residues as potential carriers for the probiotic Lactobacillus rhamnosus

Coimbra P, Innovative Food Science & Emerging Technologies. 88. 2023. http://dx.doi.org/10.1016/j.ifset.2023.103452 . 10.1016/j.ifset.2023.103452 . published Innovative Food Science & Emerging Technologies

Intestinal infection triggers mitochondria-mediated a-synuclein pathology: relevance to Parkinsons disease

Magalhães JD, Cellular and Molecular Life Sciences. 6. 80. 2023. http://dx.doi.org/10.1007/s00018-023-04819-3 . 10.1007/s00018-023-04819-3 . published Cellular and Molecular Life Sciences

The role of bacteria-mitochondria communication in the activation of neuronal innate immunity: Implications to Parkinson's Disease

Magalhães JD, International Journal of Molecular Sciences. 5. 24. 2023. http://dx.doi.org/10.3390/ijms24054339 . 10.3390/ijms24054339 . published International Journal of Molecular Sciences

Footprints of a microbial toxin from the gut microbiome to mesencephalic mitochondria

Esteves AR; Alarico S, Gut. 73 - 89. 1. 72. 2023. http://dx.doi.org/10.1136/gutjnl-2021-326023 . 10.1136/gutjnl-2021-326023 . published Gut

Self-recycling and partially conservative replication of mycobacterial methylmannose polysaccharides

Maranha A; Pereira PJB, Empadinhas N, Communications Biology. 1. 6. 2023. https://doi.org/10.1038/s42003-023-04448-3 . 10.1038/s42003-023-04448-3 . published Communications Biology

Parkinson's Disease: A Multisystem Disorder

Costa HN, Neuroscience Bulletin. 113 - 124. 1. 39. 2023. http://dx.doi.org/10.1007/s12264-022-00934-6 . 10.1007/s12264-022-00934-6 . published Neuroscience Bulletin

Enzyme promiscuity in serotonin biosynthesis, from bacteria to plants and humans

Gonçalves S, Frontiers in Microbiology. 13. 2022. http://dx.doi.org/10.3389/fmicb.2022.873555 . 10.3389/fmicb.2022.873555 . published Frontiers in Microbiology

Sequential scCO2 drying and sterilisation of alginate-gelatine aerogels for biomedical applications

Bento C, The Journal of Supercritical Fluids. 184. 2022. http://dx.doi.org/10.1016/j.supflu.2022.105570 . 10.1016/j.supflu.2022.105570 . published The Journal of Supercritical Fluids

Neurodegenerative Microbially-Shaped Diseases: Oxidative Stress Meets Neuroinflammation

Silva DF, Antioxidants. 11. 11. 2022. http://dx.doi.org/10.3390/antiox11112141 . 10.3390/antiox11112141 . published Antioxidants

The neuromicrobiology of Parkinson's disease: A unifying theory

Muñoz-Pinto MF, Ageing Research Reviews. 70. 2021. http://dx.doi.org/10.1016/j.arr.2021.101396 . 10.1016/j.arr.2021.101396 . published Ageing Research Reviews

Improved diabetic wound healing by bovine lactoferricin is associated with relevant changes in the skin immune response and microbiota

Mouritzen MV, Molecular Therapy - Methods & Clinical Development. 726 - 739. 20. 2021. https://doi.org/10.1016/j.omtm.2021.02.008 . 10.1016/j.omtm.2021.02.008 . published Molecular Therapy - Methods & Clinical Development

The Mitochondrial Ribosome: A World of Opportunities for Mitochondrial Dysfunction Toward Parkinson's Disease

Gonçalves AM, Antioxidants & Redox Signaling. 694 - 711. 8. 34. 2021. https://www.liebertpub.com/doi/10.1089/ars.2019.7997 . 10.1089/ars.2019.7997 . published Antioxidants & Redox Signaling

Microbial BMAA elicits mitochondrial dysfunction, innate immunity activation and Alzheimer's disease features in cortical neurons

Silva DF, Journal of Neuroinflammation. 332. 17. 2020. http://dx.doi.org/10.1186/s12974-020-02004-y . 10.1186/s12974-020-02004-y . published Journal of Neuroinflammation

Editorial: Interplay Between Nutrition, the Intestinal Microbiota and the Immune System

Oriá RB, Frontiers in Immunology. 11. 2020. http://dx.doi.org/10.3389/fimmu.2020.01758 . 10.3389/fimmu.2020.01758 . published Frontiers in Immunology

Stabilization of blood for long-term storage can affect antibody-based recognition of cell surface markers

Silva MB; Färnert A, Journal of Immunological Methods. 481. 2020. http://dx.doi.org/10.1016/j.jim.2020.112792 . 10.1016/j.jim.2020.112792 . published Journal of Immunological Methods

A genuine mycobacterial thermophile: Mycobacterium hassiacum growth, survival and GpgS stability at near-pasteurization temperatures

Alarico S, Microbiology. 474 - 483. 5. 166. 2020. http://dx.doi.org/10.1099/mic.0.000898 . 10.1099/mic.0.000898 . published Microbiology

Microbial BMAA and the Pathway for Parkinson's Disease Neurodegeneration

Nunes-Costa D, Frontiers in Aging Neuroscience. 12. 2020. https://doi.org/10.3389/fnagi.2020.00026 . 10.3389/fnagi.2020.00026 . published Frontiers in Aging Neuroscience

The structural characterization of a glucosylglycerate hydrolase provides insights into the molecular mechanism of mycobacterial recovery from nitrogen starvation

Cereija TB, IUCrJ. 572 - 585. 4. 6. 2019. https://doi.org/10.1107/S2052252519005372 . 10.1107/S2052252519005372 . published IUCrJ

High-Quality Draft Genome Sequences of Rare Nontuberculous Mycobacteria Isolated from Surfaces of a Hospital

Tiago I, Microbiology Resource Announcements. 21. 8. 2019. https://doi.org/10.1128/MRA.00496-19 . 10.1128/MRA.00496-19 . published Microbiology Resource Announcements

Biosynthesis of mycobacterial methylmannose polysaccharides requires a unique 1-O-methyltransferase specific for 3-O-methylated mannosides

Ripoll-Rozada J; Pereira PJB; Empadinhas N, Proceedings of the National Academy of Sciences. 201813450 - 201813450. 2019. https://www.pnas.org/content/116/3/835.long . 10.1073/pnas.1813450116 . published Proceedings of the National Academy of Sciences

Studies of antimicrobial resistance in rare mycobacteria from a nosocomial environment

Pereira SG, BMC Microbiology. 1. 19. 2019. http://dx.doi.org/10.1186/s12866-019-1428-4 . 10.1186/s12866-019-1428-4 . published BMC Microbiology

Molecular Fingerprints for a Novel Enzyme Family in Actinobacteria with Glucosamine Kinase Activity

Manso JA, mBio. 2019. https://doi.org/10.1128/mBio.00239-19 . 10.1128/mBio.00239-19 . published mBio

The Microbiome-Mitochondria Dance in Prodromal Parkinson's Disease

Cardoso SM, Empadinhas N, Frontiers in Physiology. 9. 2018. https://www.frontiersin.org/articles/10.3389/fphys.2018.00471/full . 10.3389/fphys.2018.00471 . published Frontiers in Physiology

Microbiota of Chronic Diabetic Wounds: Ecology, Impact, and Potential for Innovative Treatment Strategies

Pereira SG, Frontiers in Microbiology. 8. 2017. https://doi.org/10.3389%2Ffmicb.2017.01791 . 10.3389/fmicb.2017.01791 . published Frontiers in Microbiology

Production, crystallization and structure determination of a mycobacterial glucosylglycerate hydrolase

Cereija TB, Acta Crystallographica Section F Structural Biology Communications. 536 - 540. 9. 73. 2017. https://doi.org/10.1107%2Fs2053230x17012419 . 10.1107/S2053230X17012419 . published Acta Crystallographica Section F Structural Biology Communications

Hospital microbial surface colonization revealed during monitoring of Klebsiella spp., Pseudomonas aeruginosa, and non-tuberculous mycobacteria

Farias PG, Antonie van Leeuwenhoek. 863 - 876. 7. 110. 2017. http://dx.doi.org/10.1007/s10482-017-0857-z . 10.1007/s10482-017-0857-z . published Antonie van Leeuwenhoek

The looming tide of nontuberculous mycobacterial infections in Portugal and Brazil

Nunes-Costa D, Tuberculosis. 107 - 119. 96. 2016. http://dx.doi.org/10.1016/j.tube.2015.09.006 . 10.1016/j.tube.2015.09.006 . published Tuberculosis

Glucosylglycerate metabolism, bioversatility and mycobacterial survival

Nunes-Costa D, Glycobiology. 213 - 227. 27. 2016. http://dx.doi.org/10.1093/glycob/cww132 . 10.1093/glycob/cww132 . published Glycobiology

Octanoylation of early intermediates of mycobacterial methylglucose lipopolysaccharides

Maranha A; Clarke AJ, Empadinhas N, Scientific Reports. 1. 5. 2015. http://dx.doi.org/10.1038/srep13610 . 10.1038/srep13610 . published Scientific Reports

Structure of mycobacterial maltokinase, the missing link in the essential GlgE-pathway

Fraga JS, Scientific Reports. 5. 2015. https://doi.org/10.1038/srep08026 . 10.1038/srep08026 . published Scientific Reports

Structure of Mycobacterium thermoresistibile GlgE defines novel conformational states that contribute to the catalytic mechanism

Mendes V, Scientific Reports. 1. 5. 2015. http://dx.doi.org/10.1038/srep17144 . 10.1038/srep17144 . published Scientific Reports

The molecular biology of mycobacterial trehalose in the quest for advanced tuberculosis therapies

Nobre A, Microbiology (United Kingdom). 1547 - 1570. PART 8. 160. 2014. https://doi.org/10.1099/mic.0.075895-0 . 10.1099/mic.0.075895-0 . published Microbiology (United Kingdom)

Autophagy in the fight against tuberculosis

Bento CF, DNA and Cell Biology. 228 - 242. 4. 34. 2014. https://doi.org/10.1089/dna.2014.2745 . 10.1089/dna.2014.2745 . published DNA and Cell Biology

Mycobacterium hassiacum recovers from nitrogen starvation with up-regulation of a novel glucosylglycerate hydrolase and depletion of the accumulated glucosylglycerate

Alarico S, Scientific Reports. 1. 4. 2014. http://dx.doi.org/10.1038/srep06766 . 10.1038/srep06766 . published Scientific Reports

The plant Selaginella moellendorffii possesses enzymes for synthesis and hydrolysis of the compatible solutes mannosylglycerate and glucosylglycerate

Nobre A, Planta. 891 - 901. 3. 237. 2013. https://doi.org/10.1007/s00425-012-1808-6 . 10.1007/s00425-012-1808-6 . published Planta

A new bacterial hydrolase specific for the compatible solutes alpha-D-mannopyranosyl-(1,2)-D-glycerate and alpha-D-glucopyranosyl-(1,2)-D-glycerate

Alarico S, Enzyme and Microbial Technology. 77 - 83. 2. 52. 2013. http://dx.doi.org/10.1016/j.enzmictec.2012.10.008 . 10.1016/j.enzmictec.2012.10.008 . published Enzyme and Microbial Technology

Genome sequence of Mycobacterium hassiacum DSM 44199, a rare source of heat-stable mycobacterial proteins

Tiago I, Journal of Bacteriology. 7010 - 7011. 24. 194. 2012. DOI: https://doi.org/10.1128/JB.01880-12 . 10.1128/JB.01880-12 . published Journal of Bacteriology

Biosynthesis of mycobacterial methylglucose lipopolysaccharides

Mendes V, Natural Product Reports. 834 - 844. 8. 29. 2012. https://doi.org/10.1039/C2NP20014G . 10.1039/c2np20014g . published Natural Product Reports

Mycobacterium tuberculosis Rv2419c, the missing glucosyl-3-phosphoglycerate phosphatase for the second step in methylglucose lipopolysaccharide biosynthesis

Mendes V, Scientific Reports. 1. 1. 2011. http://dx.doi.org/10.1038/srep00177 . 10.1038/srep00177 . published Scientific Reports

Functional and structural characterization of a novel mannosyl-3-phosphoglycerate synthase from Rubrobacter xylanophilus reveals its dual substrate specificity

Empadinhas N, Molecular Microbiology. 76 - 93. 1. 79. 2011. https://doi.org/10.1111/j.1365-2958.2010.07432.x . 10.1111/j.1365-2958.2010.07432.x . published Molecular Microbiology

Diversity, biological roles and biosynthetic pathways for sugar-glycerate containing compatible solutes in bacteria and archaea

Empadinhas N, da Costa MS, Environmental Microbiology. 2056 - 2077. 8. 13. 2011. https://doi.org/10.1111/j.1462-2920.2010.02390.x . 10.1111/j.1462-2920.2010.02390.x . published Environmental Microbiology

Two alternative pathways for the synthesis of the rare compatible solute mannosylglucosylglycerate in Petrotoga mobilis

Fernandes C, Journal of Bacteriology. 1624 - 1633. 6. 192. 2010. https://doi.org/10.1128/JB.01424-09 . 10.1128/JB.01424-09 . published Journal of Bacteriology

Biochemical characterization of the maltokinase from Mycobacterium bovis BCG

Mendes V, BMC Biochemistry. 2010. https://doi.org/10.1186/1471-2091-11-21 . 10.1186/1471-2091-11-21 . published BMC Biochemistry

Identification of the mycobacterial glucosyl-3-phosphoglycerate synthase

Empadinhas N, FEMS Microbiology Letters. 195 - 202. 2. 280. 2008. https://doi.org/10.1111/j.1574-6968.2007.01064.x . 10.1111/j.1574-6968.2007.01064.x . published FEMS Microbiology Letters

Crystallization and preliminary crystallographic analysis of mannosyl-3-phosphoglycerate synthase from Rubrobacter xylanophilus

Sá-Moura B, Acta Crystallographica Section F: Structural Biology and Crystallization Communications. 760 - 763. 8. 64. 2008. https://doi.org/10.1107/S1744309108021490 . 10.1107/S1744309108021490 . published Acta Crystallographica Section F: Structural Biology and Crystallization Communications

To be or not to be a compatible solute: Bioversatility of mannosylglycerate and glucosylglycerate

Empadinhas N, da Costa MS, Systematic and Applied Microbiology. 159 - 168. 3. 31. 2008. https://doi.org/10.1016/j.syapm.2008.05.002 . 10.1016/j.syapm.2008.05.002 . published Systematic and Applied Microbiology

Osmoadaptation mechanisms in prokaryotes: Distribution of compatible solutes

Empadinhas N, da Costa MS, International Microbiology. 151 - 161. 3. 11. 2008. https://europepmc.org/article/med/18843593 . 10.2436/20.1501.01.55 . published International Microbiology

Mycobacterium tuberculosis glucosyl-3-phosphoglycerate synthase: Structure of a key enzyme in methylglucose lipopolysaccharide biosynthesis

Pereira PJB, PLoS ONE. 11. 3. 2008. https://doi.org/10.1371/journal.pone.0003748 . 10.1371/journal.pone.0003748 . published PLoS ONE

Molecular and physiological role of the trehalose-hydrolyzing a-glucosidase from Thermus thermophilus HB27

Alarico S, Journal of Bacteriology. 2298 - 2305. 7. 190. 2008. http://www.scopus.com/inward/record.url?eid=2-s2.0-41549086172&partnerID=MN8TOARS . 10.1128/JB.01794-07 . published Journal of Bacteriology

A Unique Combination of Genetic Systems for the Synthesis of Trehalose in Rubrobacter xylanophilus: Properties of a Rare Actinobacterial TreT

Nobre A, Journal of Bacteriology. 7939 - 7946. 24. 190. 2008. http://dx.doi.org/10.1128/jb.01055-08 . 10.1128/jb.01055-08 . published Journal of Bacteriology

Single-step pathway for synthesis of glucosylglycerate in Persephonella marina

Fernandes C, Journal of Bacteriology. 4014 - 4019. 11. 189. 2007. http://www.scopus.com/inward/record.url?eid=2-s2.0-34249786874&partnerID=MN8TOARS . 10.1128/JB.00075-07 . published Journal of Bacteriology

Organic solutes in Rubrobacter xylanophilus: The first example of di-myo-inositol-phosphate in a thermophile

Empadinhas N, Extremophiles. 667 - 673. 5. 11. 2007. http://www.scopus.com/inward/record.url?eid=2-s2.0-34548303944&partnerID=MN8TOARS . 10.1007/s00792-007-0084-z . published Extremophiles

Mannosylglycerate is essential for osmotic adjustment in Thermus thermophilus strains HB27 and RQ-1

Alarico S, Extremophiles. 833 - 840. 6. 11. 2007. http://www.scopus.com/inward/record.url?eid=2-s2.0-35748948644&partnerID=MN8TOARS . 10.1007/s00792-007-0106-x . published Extremophiles

Glucosylglycerate biosynthesis in the deepest lineage of the Bacteria: Characterization of the thermophilic proteins GpgS and GpgP from Persephonella marina

Costa J, Journal of Bacteriology. 1648 - 1654. 5. 189. 2007. http://www.scopus.com/inward/record.url?eid=2-s2.0-33947366922&partnerID=MN8TOARS . 10.1128/JB.00841-06 . published Journal of Bacteriology

Bifunctional CTP:inositol-1-phosphate cytidylyltransferase/CDP-inositol: Inositol-1-phosphate transferase, the key enzyme for di-myo-inositol-phosphate synthesis in several (hyper)thermophiles

Rodrigues MV, Journal of Bacteriology. 5405 - 5412. 15. 189. 2007. http://www.scopus.com/inward/record.url?eid=2-s2.0-34547629796&partnerID=MN8TOARS . 10.1128/JB.00465-07 . published Journal of Bacteriology

Characterization of the biosynthetic pathway of glucosylglycerate in the archaeon Methanococcoides burtonii

Costa J, Journal of Bacteriology. 1022 - 1030. 3. 188. 2006. http://www.scopus.com/inward/record.url?eid=2-s2.0-31344453995&partnerID=MN8TOARS . 10.1128/JB.188.3.1022-1030.2006 . published Journal of Bacteriology

Diversity and biosynthesis of compatible solutes in hyper/thermophiles

Empadinhas N, da Costa MS, International Microbiology. 199 - 206. 3. 9. 2006. http://www.scopus.com/inward/record.url?eid=2-s2.0-33750584278&partnerID=MN8TOARS . published International Microbiology

Distribution of genes for synthesis of trehalose and mannosylglycerate in Thermus spp. and direct correlation of these genes with halotolerance

Alarico S, Applied and Environmental Microbiology. 2460 - 2466. 5. 71. 2005. http://www.scopus.com/inward/record.url?eid=2-s2.0-18444382346&partnerID=MN8TOARS . 10.1128/AEM.71.5.2460-2466.2005 . published Applied and Environmental Microbiology

Meiothermus timidus sp. nov., a new slightly thermophilic yellow-pigmented species

Pires AL, FEMS Microbiology Letters. 39 - 45. 1. 245. 2005. http://www.scopus.com/inward/record.url?eid=2-s2.0-15744405109&partnerID=MN8TOARS . 10.1016/j.femsle.2005.02.011 . published FEMS Microbiology Letters

Specialized Roles of the Two Pathways for the Synthesis of Mannosylglycerate in Osmoadaptation and Thermoadaptation of Rhodothermus marinus

Borges N, Journal of Biological Chemistry. 9892 - 9898. 11. 279. 2004. http://www.scopus.com/inward/record.url?eid=2-s2.0-1642279326&partnerID=MN8TOARS . 10.1074/jbc.M312186200 . published Journal of Biological Chemistry

A gene from the mesophilic bacterium Dehalococcoides ethenogenes encodes a novel mannosylglycerate synthase

Empadinhas N, Journal of Bacteriology. 4075 - 4084. 13. 186. 2004. http://www.scopus.com/inward/record.url?eid=2-s2.0-3042523198&partnerID=MN8TOARS . 10.1128/JB.186.13.4075-4084.2004 . published Journal of Bacteriology

The Bacterium Thermus thermophilus , Like Hyperthermophilic Archaea, Uses a Two-Step Pathway for the Synthesis of Mannosylglycerate

Empadinhas N, Applied and Environmental Microbiology. 3272 - 3279. 6. 69. 2003. http://dx.doi.org/10.1128/aem.69.6.3272-3279.2003 . 10.1128/aem.69.6.3272-3279.2003 . published Applied and Environmental Microbiology

Gamma-Proteobacteria Aquicella lusitana gen. nov., sp. nov., and Aquicella siphonis sp. nov. Infect Protozoa and Require Activated Charcoal for Growth in Laboratory Media

Santos P, Applied and Environmental Microbiology. 6533 - 6540. 11. 69. 2003. http://www.scopus.com/inward/record.url?eid=2-s2.0-0242573382&partnerID=MN8TOARS . 10.1128/AEM.69.11.6533-6540.2003 . published Applied and Environmental Microbiology

Rubritepida flocculans gen. nov., sp. nov., a New Slightly Thermophilic Member of the a-1 Subclass of the Proteobacteria

Alarico S, Systematic and Applied Microbiology. 198 - 206. 2. 25. 2002. http://dx.doi.org/10.1078/0723-2020-00116 . 10.1078/0723-2020-00116 . published Systematic and Applied Microbiology

Albidovulum inexpectatum gen. nov., sp. nov., a nonphotosynthetic and slightly thermophilic bacterium from a marine hot spring that is very closely related to members of the photosynthetic genus Rhodovulum

Albuquerque L, Applied and Environmental Microbiology. 4266 - 4273. 9. 68. 2002. http://www.scopus.com/inward/record.url?eid=2-s2.0-0036729238&partnerID=MN8TOARS . 10.1128/AEM.68.9.4266-4273.2002 . published Applied and Environmental Microbiology

Pathway for the synthesis of mannosylglycerate in the hyperthermophilic archaeon Pyrococcus horikoshii: Biochemical and genetic characterization of key enzymes

Empadinhas N, Journal of Biological Chemistry. 43580 - 43588. 47. 276. 2001. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035941355&partnerID=MN8TOARS . 10.1074/jbc.M108054200 . published Journal of Biological Chemistry

Biosynthesis of mannosylglycerate in the thermophilic bacterium Rhodothermus marinus. Biochemical and genetic characterization of a mannosylglycerate synthase

Martins LO, Journal of Biological Chemistry. 35407 - 35414. 50. 274. 1999. http://www.scopus.com/inward/record.url?eid=2-s2.0-0033544948&partnerID=MN8TOARS . 10.1074/jbc.274.50.35407 . published Journal of Biological Chemistry

All projects

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Information of exclusive responsibility of the researcher 17-12-2023 , from platform CIÊNCIAVITAE.

2023 - 2026

Validation of bacterial-derived anti-inflammatory mediators in gut-first PD

CP code: SC01

Researcher

Universidade de Coimbra Centro de Inovação em Biomedicina e Biotecnologia; Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: Cure Parkinson's

2023 - 2025

Exploring bacterial interactions to find novel molecules to combat the antimicrobial resistance catastrophe

2022.06809.PTDC

Researcher

Universidade de Coimbra Centro de Inovação em Biomedicina e Biotecnologia; Centro de Neurociências e Biologia Celular da Universidade de Coimbra

Funders: Fundação para a Ciência e a Tecnologia

2022 - 2025

Nontuberculous mycobacteria from drinking water: beyond the lung disease epidemic

PTDC/BIA-MIC/0122/2021

Principal investigator

Universidade de Coimbra Centro de Inovação em Biomedicina e Biotecnologia; Administração Regional de Saúde do Centro IP; Universidade do Porto Instituto de Saúde Pública

Funders: Fundação para a Ciência e a Tecnologia

2022 - 2023

Microbiome-miRNAs axis in Parkinsons disease: involvement of mitochondrial mediated inflammatory response

EXPL/MED-NEU/1515/2021

Researcher

Centro de Neurociências e Biologia Celular da Universidade de Coimbra; Universidade de Coimbra Centro de Inovação em Biomedicina e Biotecnologia

Funders: Fundação para a Ciência e a Tecnologia

2021 - 2025

DYNABrain - Dynamic Brain Function: Towards the Understanding and Treatment of Brain Disorders (ERA Chairs - Institutional)

H2020-WIDESPREAD-2018-2020-6, ID: 952422

Other

Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: European Commission

2021 - 2025

CIBB - Center for Innovative Biomedicine and Biotechnology - Associate Laboratory (Institutional)

LA/P/0058/2020

Researcher

Universidade de Coimbra Centro de Inovação em Biomedicina e Biotecnologia

Funders: Fundação para a Ciência e a Tecnologia

2021 - 2023

The Gut-Immune-Brain Axis in Parkinson disease

PTDC/MED-NEU/3644/2020

Co-Principal Investigator (Co-PI)

Universidade de Coimbra Centro de Neurociências e Biologia Celular; Universidade de Coimbra Centro de Inovação em Biomedicina e Biotecnologia

Funders: Fundação para a Ciência e a Tecnologia

2020 - 2021

Sustainable and dual function polymeric edible films: a probiotic and antioxidant delivery food packaging system

Prémio Projetos Semente de I&D "Era pós-COVID 19: uma sociedade mais sustentável, resiliente e justa

Researcher

Universidade de Coimbra

Funders: Universidade de Coimbra/Santander

2020 - 2023

CIBB - Center for Innovative Biomedicine and Biotechnology (Institutional)

UIDB/04539/2020 and UIDP/04539/2020

Researcher

Universidade de Coimbra Centro de Inovação em Biomedicina e Biotecnologia (CIBB)

Funders: Fundação para a Ciência e a Tecnologia

2018 - 2018

Prevalência de micobactérias não-tuberculosas em ambiente doméstico

Prémio Thomé Villar/Boehringer Ingelheim 2017

Co-Principal Investigator (Co-PI)

Universidade do Porto Instituto de Saúde Pública; Universidade de Coimbra Centro de Inovação em Biomedicina e Biotecnologia

Funders: Sociedade Portuguesa de Pneumologia; Boehringer Ingelheim Portugal

2018 - 2022

Green method to prepare sterilized biopolymers based aerogel

PTDC/EQU-EPQ/32625/2017

Researcher

Universidade de Coimbra; Universidade de Coimbra Centro de Neurociências e Biologia Celular; Universidade de Coimbra Centro de Inovação em Biomedicina e Biotecnologia

Funders: Fundação para a Ciência e a Tecnologia

2018/06/15 - 2021/12/31

An intriguing mycobacterial polysaccharide: recycling, replication and beyond

PTDC/BTM-TEC/29221/2017

Principal investigator

Universidade de Coimbra Centro de Neurociências e Biologia Celular; Universidade de Coimbra Centro de Inovação em Biomedicina e Biotecnologia; Universidade do Porto Instituto de Biologia Molecular e Celular; Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde

Funders: Fundação para a Ciência e a Tecnologia

2017 - 2021

HealthyAging2020 (WP9 - Deciphering microbiome signatures in chronic diseases for early diagnosis and modulation therapies) (Institutional-HR)

CENTRO-01-0145-FEDER-000012-N2323

Researcher

Universidade de Coimbra - Centro de Neurociências e Biologia Celular; CNC.IBILI

Funders: European Regional Development Fund; Comissão de Coordenação e Desenvolvimento Regional do Centro

2017 - 2020

The toxinogenic gut microbiome in sporadic Parkinson's Disease: a quest for "antiPDbiotics"

Mantero Belard Prize 2016 - MB-40-2016

Co-Principal Investigator (Co-PI)

Universidade de Coimbra Centro de Neurociências e Biologia Celular; Universidade de Coimbra Centro de Inovação em Biomedicina e Biotecnologia

Funders: Santa Casa da Misericórdia de Lisboa

2016 - 2016

The impairment of neuronal metabolism by gut microbiome effectors

FMUC-BST-2016-221

Researcher

Universidade de Coimbra Faculdade de Medicina

Funders: Faculdade de Medicina, Universidade de Coimbra & Banco Santander

2016 - 2018

Microcare - Microbiome of diabetic ulcers: early diagnosis, prognosis and therapy

FIS-2015-01_DIA_20150630-144

Co-Principal Investigator (Co-PI)

Universidade de Coimbra Centro de Neurociências e Biologia Celular; CNC.IBILI

Funders: Infarmed - Fundo para a Investigação em Saúde

2014 - 2015

Produção e comercialização global de compostos microbianos para investigação

InovC 2014

Principal investigator

Universidade de Coimbra

Funders: European Regional Development Fund

2013 - 2015

Ambiguity and virulence in a human pathogen

PTDC/BBB-BEP/0695/2012

Researcher

Instituto de Biologia Molecular e Celular; Centro de Neurociências e Biologia Celular da Universidade de Coimbra

Funders: Fundação para a Ciência e a Tecnologia

2013 - 2015

Biosynthesis of rare methylmannose polysaccharides in nontuberculous mycobacteria

PTDC/BIA-MIC/2779/2012

Principal investigator

Universidade de Coimbra Centro de Neurociências e Biologia Celular; Universidade do Porto Instituto de Biologia Molecular e Celular; Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica

Funders: Fundação para a Ciência e a Tecnologia

2012 - 2014

Unravelling the early steps in the biosynthesis of the mycobacterial MGLP

Grant 120123

Principal investigator

Universidade de Coimbra - Centro de Neurociências e Biologia Celular

Funders: Mizutani Foundation for Glycoscience

2011 - 2014

Pathway for the synthesis of the mycobacterial MGLP. Biochemical and structural characterization of the key enzymes

PTDC/BIA-PRO/110523/2009

Principal investigator

Centro de Neurociências e Biologia Celular da Universidade de Coimbra; Universidade do Porto Instituto de Biologia Molecular e Celular

Funders: Fundação para a Ciência e a Tecnologia

2011 - 2013

The enigmatic mycobacterial maltokinase

PTDC/BIA-BCM/112459/2009

Principal investigator

Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: Fundação para a Ciência e a Tecnologia

2009 - 2010

Characterization and evolution of a rare glycosyltransferase from the anti-tumor producing bacteria of the genus Actinosynnema (PI)

Acordo cultural 2010 Eslováquia 124626903612592

Principal investigator

Universidade de Coimbra Centro de Neurociências e Biologia Celular

2009 - 2010

Characterization and evolution of a rare glycosyltransferase from the antitumor producing bacteria of the genus Actinosynnema

Acordo Cultural 2010 Eslováquia 124626903612592

Principal investigator

Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: Fundação para a Ciência e a Tecnologia

2008 - 2010

Cloning, expression and regulation of genes for the synthesis of compatible solutes in Thermus thermophilus

Acção Nº E-9/08

Researcher

Universidade de Coimbra; Centro de Neurociências e Biologia Celular da Universidade de Coimbra

Funders: Conselho de Reitores das Universidades Portuguesas, Portugal

2005 - 2008

Nature´s shields to environmental stress. Biosynthesis of compatible solutes in extremely radiation-resistant Rubrobacter spp.

POCI/BIA-MIC/56511/2004

Researcher

Centro de Neurociências e Biologia Celular da Universidade de Coimbra; Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica

Funders: Fundação para a Ciência e a Tecnologia

2005 - 2006

O Mundo dos Micróbios - Colecção Portuguesa de Bactérias (CPB) e Laboratório Acreditado de Controlo Microbiológico

REEQ/851/BIO/2005

Researcher

Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: Fundação para a Ciência e a Tecnologia

2005 - 2008

Compatible solutes from extremophiles: screening, biosynthesis and heterologous production

POCI/V.5/A0005/2005

Researcher

Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: Fundação para a Ciência e a Tecnologia

2004 - 2006

Hotsolutes: New applications for compatible solutes from Extremophiles

COOP-CT-2003-508644

Post-doc Fellow

Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica; Centro de Neurociências e Biologia Celular da Universidade de Coimbra

Funders: European Commission

2002 - 2004

Hypersolutes: Exploiting new solutes from hyperthermophiles for the preservation of biomaterials: cell factories for production of hypersolutes

QLK3-CT-2000-00640

PhD Student Fellow

Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica; Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: European Commission

2001 - 2004

Towards the Utilization of Cell-Reactors for the Production of Mannosylglycerate, an Enzyme Stabilizer from Hyperthermophiles

POCTI/BIO/35715/1999

PhD Student Fellow

Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica

Funders: Fundação para a Ciência e a Tecnologia

1997 - 1999

Extremophiles as cell factories

BIO4960488

Master Student Fellow

Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica

Funders: European Commission

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