Mariana Biscaia Caleiras

Unveiling the impact of membrane fluidity in shaping lipid-based drug delivery systems development

Mariana Biscaia-Caleiras; Ana Sofia Lourenço; João Nuno Moreira; Sérgio Simões, Biochimica et Biophysica Acta (BBA) - Biomembranes. 2026. https://doi.org/10.1016/j.bbamem.2025.184461 . 10.1016/j.bbamem.2025.184461 . Biochimica et Biophysica Acta (BBA) - Biomembranes

Integrating microfluidics and streamlined remote drug loading: one step closer to continuous manufacturing of liposomal injectables containing small drugs

Biscaia-Caleiras, Mariana; Lopes, Diana; Henriques, Carolina; Lourenço, Ana Sofia; Nunes, António; Bañobre, Manuel; Moreira, João Nuno; Simões, Sérgio, International Journal of Pharmaceutics. 682. 2025. https://doi.org/10.1016/j.ijpharm.2025.125973 . 10.1016/j.ijpharm.2025.125973 . published International Journal of Pharmaceutics

Implementation of design of experiments in liposome manufacturing: ethanol injection and extrusion as a case study

Biscaia-Caleiras, Mariana; Fiteiro, Joana; Lopes, Diana; Fidalgo, Tiago; Lourenço, Ana Sofia; Moreira, João Nuno; Simões, Sérgio, Journal of Drug Delivery Science and Technology. 112. 2025. https://doi.org/10.1016/j.jddst.2025.107236 . 10.1016/j.jddst.2025.107236 . Journal of Drug Delivery Science and Technology

Bridging membrane fluidity studies with a predictive model of drug encapsulation to address industrial challenges of liposomal injectables manufacturing

Mariana Biscaia-Caleiras; Nuno Fonseca; Ana Sofia Lourenço; António Nunes; Abel Ferreira; João Nuno Moreira; Sérgio Simões, Drug Delivery and Translational Research. 2025. https://doi.org/10.1007/s13346-025-01807-x . 10.1007/s13346-025-01807-x . Drug Delivery and Translational Research

Rational formulation and industrial manufacturing of lipid-based complex injectables: Landmarks and trends

Biscaia-Caleiras, Mariana; Fonseca, Nuno A.; Lourenço, Ana Sofia; Moreira, João Nuno; Simões, Sérgio, Journal of Controlled Release. 617 - 639. 373. 2024. https://doi.org/10.1016/j.jconrel.2024.07.021 . 10.1016/j.jconrel.2024.07.021 . Journal of Controlled Release