Miguel Monteiro Lopes

Isolation of Adeno-associated Viral Vectors Through a Single-step and Semi-automated Heparin Affinity Chromatography Protocol

Lopes, Miguel M.; Lopes, Sara M.; Baganha, Rafael; Henriques, Carina; Silva, Ana C.; Lobo, Diana D.; Cortes, Luisa; Pereira de Almeida, Luis ; Nobre, Rui Jorge, Journal of Visualized Experiments. 206. 2024. https://doi.org/10.3791/66550 . 10.3791/66550 . published Journal of Visualized Experiments

Viral-based animal models in polyglutamine disorders

Henriques, Carina; Lopes, Miguel M; Silva, Ana C; Lobo, Diana D; Badin, Romina Aron; Hantraye, Philippe; Pereira de Almeida, Luís; Nobre, Rui Jorge, Brain. 1166 - 1189. 4. 147. 2024. http://dx.doi.org/10.1093/brain/awae012 . 10.1093/brain/awae012 . published Brain

A new protocol for whole-brain biodistribution analysis of AAVs by tissue clearing, light-sheet microscopy and semi-automated spatial quantification

Miguel M. Lopes; Jacques Paysan; José Rino; Sara M. Lopes; Luís Pereira de Almeida; Luísa Cortes; Rui Jorge Nobre, Gene Therapy. 2022. https://doi.org/10.1038/s41434-022-00372-z . 10.1038/s41434-022-00372-z . Gene Therapy

MiRNA-Mediated Knockdown of ATXN3 Alleviates Molecular Disease Hallmarks in a Mouse Model for Spinocerebellar Ataxia Type 3

Rui Jorge Nobre; Diana D. Lobo; Carina Henriques; Sonia P. Duarte; Sara M. Lopes; Ana C. Silva; Miguel M. Lopes; et al, Nucleic Acid Therapeutics. 2021. https://doi.org/10.1089/nat.2021.0020 . 10.1089/nat.2021.0020 . Nucleic Acid Therapeutics

ULK overexpression mitigates motor deficits and neuropathology in mouse models of Machado-Joseph disease

Vasconcelos-Ferreira, Ana; Martins, Inês Morgado; Lobo, Diana; Pereira, Dina; Lopes, Miguel M.; Faro, Rosário; Lopes, Sara M.; et al, Molecular Therapy. 2021. http://dx.doi.org/10.1016/j.ymthe.2021.07.012 . 10.1016/j.ymthe.2021.07.012 . in press Molecular Therapy