Publications
Information about journal articles, updated at 17-12-2023, from platform CIÊNCIAVITAE.
Restoration of c-Src/Fyn Proteins Rescues Mitochondrial Dysfunction in Huntington's Disease
Fão L; Coelho, Patrícia; Duarte, Luís; Vilaça, Rita; Hayden, Michael R.; Mota, Sandra I.; Rego, Ana Cristina, Antioxidants & Redox Signaling. 2022. http://dx.doi.org/10.1089/ars.2022.0001 . 10.1089/ars.2022.0001 . Antioxidants & Redox Signaling
Mitochondrial function and dynamics in neural stem cells and neurogenesis: Implications for neurodegenerative diseases
Coelho, Patrícia; Fão L; Mota, Sandra; Rego, A. Cristina, Ageing Research Reviews. 80. 2022. http://dx.doi.org/10.1016/j.arr.2022.101667 . 10.1016/j.arr.2022.101667 . Ageing Research Reviews
c-Src/Fyn decreased levels in Huntington’s Disease – impact on mitochondrial function and ROS formation.
Fão, Lígia; Coelho, Patrícia; Mota, Sandra I.; Ana Cristina Carvalho Rego, SPN 2021. 01-12-2021.
Neuronal cell-based high-throughput screen for enhancers of mitochondrial function reveals luteolin as a modulator of mitochondria-endoplasmic reticulum coupling
Naia, Luana; Pinho, Catarina M.; Dentoni, Giacomo; Liu, Jianping; Leal, Nuno Santos; Ferreira, Duarte M. S.; Schreiner, Bernadette; et al, BMC Biology. 1. 19. 2021. http://dx.doi.org/10.1186/s12915-021-00979-5 . 10.1186/s12915-021-00979-5 . BMC Biology
Macroautophagy and Mitophagy in Neurodegenerative Disorders: Focus on Therapeutic Interventions
Magalhães, João Duarte; Fão L; Vilaça, Rita; Cardoso, Sandra Morais; Rego, Ana Cristina, Biomedicines. 11. 9. 2021. http://dx.doi.org/10.3390/biomedicines9111625 . 10.3390/biomedicines9111625 . Biomedicines
Mitochondrial SIRT3 confers neuroprotection in Huntington's disease by regulation of oxidative challenges and mitochondrial dynamics
Naia, Luana; Carmo, Catarina; Campesan, Susanna; Fão, Lígia; Cotton, Victoria E.; Valero, Jorge; Lopes, Carla; et al, Free Radical Biology and Medicine. 163 - 179. 163. 2021. http://dx.doi.org/10.1016/j.freeradbiomed.2020.11.031 . 10.1016/j.freeradbiomed.2020.11.031 . Free Radical Biology and Medicine
Mitochondrial and redox-based therapeutic strategies in Huntington's disease
Fão, Lígia, Antioxidants and Redox Signaling. 2020. https://pubmed.ncbi.nlm.nih.gov/32498555/ . 10.1089/ars.2019.8004 . Antioxidants and Redox Signaling
Shaping the Nrf2-ARE-related pathways in Alzheimer’s and Parkinson’s diseases
Fão, Lígia, Ageing Research Reviews. 2019. http://dx.doi.org/10.1016/j.arr.2019.100942 . 10.1016/j.arr.2019.100942 . Ageing Research Reviews
Modified Glutamatergic Postsynapse in Neurodegenerative Disorders
Fão, Lígia, Neuroscience. 2019. http://dx.doi.org/10.1016/j.neuroscience.2019.12.002 . 10.1016/j.neuroscience.2019.12.002 . Neuroscience
c-Src regulated Nrf2 activity through PKCd after an oxidant stimulus.
Fão, Lígia, Portuguese Society of Neurosciences. . 01-06-2019.
c-Src/Fyn role in Huntington’s Disease progression
Fão, Lígia; Sandra Isabel Freitas Mota; Ana Cristina Carvalho Rego, 23rd Annual Meeting of the Portuguese Society of Human Genetics. . 14-11-2019.
c-Src regulates Nrf2 activity through PKCd after oxidant stimulus
Fão, Lígia, Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 2019. http://dx.doi.org/10.1016/j.bbamcr.2019.01.011 . 10.1016/j.bbamcr.2019.01.011 . Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
Oligomeric amyloid-beta peptide-induced redox dendritic mitochondrial changes in mature hippocampal neurons: role of NMDA receptors and Src kinase.
Fão, Lígia, . MitoPorto International Symposium. 13-07-2018.
Regulation of Nrf2 activity by Src Kinase Family and PKCd after an oxidant stimulus.
Fão, Lígia, 9th Meeting on Signal Transduction. 21-09-2018.
Crosstalk between Src kinase and Nrf2 following oxidant stimulus - mitochondria and nucleus as relevant subcellular targets; and NMDA receptor-dependent redox changes and modified dendritic mitochondria following exposure to oligomeric amyloid-beta peptide in mature hippocampal neurons.
Fão, Lígia, MitoPorto International Symposium. 26-05-2017.
Induction of oxidative stress by amyloid-beta1-42 in mature hippocampal neurons: linking Src activity to Alzheimer’s disease.
Fão, Lígia, . XL Portuguese Genetics Conference. . 03-06-2016.
Role of src kinase in oligomeric amyloid-betainduced early oxidative stress in mature hippocampal neurons - a link to alzheimer’s disease.
Fão, Lígia; Sandra Isabel Freitas Mota; Ana Cristina Carvalho Rego, Synaptic Functions & Dysfunctions in Brain Disease – ISN. 01-06-2016.
Amyloid-beta peptide-evoked Src signaling and redox changes in hippocampal cells
Fão, Lígia, master. Universidade de Coimbra Faculdade de Ciencias e Tecnologia . 21-09-2016.
5 18 out of 18 Publications
All projects
Information of exclusive responsibility of the researcher 17-12-2023 , from platform CIÊNCIAVITAE.
2021/11/01 - 2022/10/31
Examining Fyn/Src in Huntington’s Disease cell models.
1159/ACREGO
Technical development
2018/10/01 - 2019/09/30
Exploring striatal postsynaptic SAPAP3 in Huntington’s disease
948/ACREGO
2018/09 - 2021/08
Transcriptional activity modulation in Alzheimer's disease by inhibitors of histone deacetylases
PTDC/MED-TOX/32316/2017
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Funders: Fundação para a Ciência e a Tecnologia
2017/06/01 - 2020/11/30
“HEALTHY AGING 2020 – WP4 - Changes in neurogenesis and mitochondrial function in Alzheimer's and Huntington's disease.”
CENTRO-01-0145-FEDER-000012
Research Fellow
Universidade de Coimbra Centro de Neurociências e Biologia Celular
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