Henrique Bernardo da Silva

Adenosine A2A Receptor Up-Regulation Pre-Dates Deficits of Synaptic Plasticity and of Memory in Mice Exposed to Aß1–42 to Model Early Alzheimer’s Disease

Cátia R. Lopes; António C. Silva; Henrique B. Silva; Paula M. Canas; Paula Agostinho; Rodrigo A. Cunha; João Pedro Lopes, Biomolecules. 2023. https://doi.org/10.3390/biom13081173 . 10.3390/biom13081173 . Biomolecules

Simultaneous Alteration of the Circadian Variation of Memory, Hippocampal Synaptic Plasticity, and Metabolism in a Triple Transgenic Mouse Model of Alzheimer’s Disease

Carvalho da Silva, António M.; Lemos, Cristina; Silva, Henrique B.; Ferreira, Ildete L.; Tomé, Angelo R.; Rego, A. Cristina; Cunha, Rodrigo A., Frontiers in Aging Neuroscience. 14. 2022. http://dx.doi.org/10.3389/fnagi.2022.835885 . 10.3389/fnagi.2022.835885 . Frontiers in Aging Neuroscience

Increased ATP Release and Higher Impact of Adenosine A2A Receptors on Corticostriatal Plasticity in a Rat Model of Presymptomatic Parkinson’s Disease

Gonçalves, Francisco Q.; Matheus, Filipe C.; Silva, Henrique B.; Real, Joana I.; Rial, Daniel; Rodrigues, Ricardo J.; Oses, Jean-Pierre; et al, Molecular Neurobiology. 1659 - 1674. 3. 60. 2022. http://dx.doi.org/10.1007/s12035-022-03162-1 . 10.1007/s12035-022-03162-1 . Molecular Neurobiology

Exercise decreases aberrant corticostriatal plasticity in an animal model of l-DOPA-induced dyskinesia.

Silva, Henrique, American journal of physiology. Regulatory, integrative and comparative physiology. 2021. https://doi.org/10.1152/ajpregu.00295.2020 . 10.1152/ajpregu.00295.2020 . American journal of physiology. Regulatory, integrative and comparative physiology

Motor Deficits Coupled to Cerebellar and Striatal Alterations in Ube3am-/p+ Mice Modelling Angelman Syndrome Are Attenuated by Adenosine A2A Receptor Blockade

Ana Moreira-de-Sá; Francisco Q. Gonçalves; João P. Lopes; Henrique B. Silva; Ângelo R. Tomé; Rodrigo A. Cunha; Paula M. Canas, Molecular Neurobiology. 2543 - 2557. 6. 58. 2021. https://doi.org/10.1007/s12035-020-02275-9 . 10.1007/s12035-020-02275-9 . Molecular Neurobiology

Neuromodulation and neuroprotective effects of chlorogenic acids in excitatory synapses of mouse hippocampal slices

Silva, Henrique, Scientific Reports. 1. 11. 2021. http://dx.doi.org/10.1038/s41598-021-89964-0 . 10.1038/s41598-021-89964-0 . Scientific Reports

Increased ATP release and CD73-mediated adenosine A2A receptor activation mediate convulsion-associated neuronal damage and hippocampal dysfunction

Augusto, Elisabete; Gonçalves, Francisco Q.; Real, Joana E.; Silva, Henrique B.; Pochmann, Daniela; Silva, Tiago S.; Matos, Marco; et al, Neurobiology of Disease. 157. 2021. http://dx.doi.org/10.1016/j.nbd.2021.105441 . 10.1016/j.nbd.2021.105441 . Neurobiology of Disease

Control of NMDA Receptor-Mediated Currents by Adenosine A1 and A2A Receptors Within the Basolateral Amygdala

Silva, Henrique; Anna Pliássova; Margarida Henriques; Henrique B. Silva; Paula Agostinho; Rodrigo A. Cunha; Samira G. Ferreira, Journal of Caffeine and Adenosine Research. 61 - 70. 2. 10. 2020. http://dx.doi.org/10.1089/caff.2019.0024 . 10.1089/caff.2019.0024 . Journal of Caffeine and Adenosine Research

Adenosine A2A receptors format long-term depression and memory strategies in a mouse model of Angelman syndrome

Silva, Henrique, Neurobiology of Disease. 105137 - 105137. 146. 2020. http://dx.doi.org/10.1016/j.nbd.2020.105137 . 10.1016/j.nbd.2020.105137 . Neurobiology of Disease

Synaptic and memory dysfunction in a ß-amyloid model of early Alzheimer's disease depends on increased formation of ATP-derived extracellular adenosine

Silva, Henrique; Goncalves, Francisco Q.; Lopes, Joao P.; Silva, Henrique B.; Lemos, Cristina; Silva, Antonio C.; Goncalves, Nell; et al, Neurobiology of Disease. 2019. http://dx.doi.org/10.1016/j.nbd.2019.104570 . 10.1016/j.nbd.2019.104570 . Neurobiology of Disease

Expression of potassium channels is relevant for cell survival and migration in a murine bone marrow stromal cell line

Silva, Henrique B.; Rodrigues, Deivid C.; Andrade, Raiana; Teixeira, Gabriel H. G. S. F.; Stelling, Mariana P.; Ponte, Cristiano G.; Nascimento, Jose H. M.; et al, Journal of Cellular Physiology. 2019. https://publons.com/publon/19495346/ . 10.1002/JCP.28441 . Journal of Cellular Physiology

Adenosine A1 and A2A receptors differently control synaptic plasticity in the mouse dorsal and ventral hippocampus

Reis, Sara L.; Silva, Henrique B.; Almeida, Margarida; Cunha, Rodrigo A.; Simoes, Ana P.; Canas, Paula M., Journal of Neurochemistry. 2019. https://publons.com/publon/28688848/ . 10.1111/JNC.14816 . Journal of Neurochemistry

Impact of Caffeine Consumption on Type 2 Diabetes-Induced Spatial Memory Impairment and Neurochemical Alterations in the Hippocampus

Duarte, Joao M. N.; Skoug, Cecilia; Silva, Henrique B.; Carvalho, Rui A.; Gruetter, Rolf; Cunha, Rodrigo A., Frontiers in Neuroscience. 2019. https://publons.com/publon/6660710/ . 10.3389/FNINS.2018.01015 . Frontiers in Neuroscience

Neuronal adenosine A2A receptors are critical mediators of neurodegeneration triggered by convulsions

Canas, P.M.; Porciúncula, L.O.; Simões, A.P.; Augusto, E.; Silva, H.B.; Machado, N.J.; Gonçalves, N.; et al, eNeuro. 6. 5. 2018. http://www.scopus.com/inward/record.url?eid=2-s2.0-85059796352&partnerID=MN8TOARS . 10.1523/ENEURO.0385-18.2018 . eNeuro

Adenosine A2A Receptors in the Rat Prelimbic Medial Prefrontal Cortex Control Delay-Based Cost-Benefit Decision Making

Silva, H.; Leffa, Douglas T.; Pandolfo, Pablo; Goncalves, Nelio; Machado, Nuno J.; de Souza, Carolina M.; Real, Joana I.; et al, Frontiers in Molecular Neuroscience. 11. 2018. http://dx.doi.org/10.3389/fnmol.2018.00475 . 10.3389/fnmol.2018.00475 . Frontiers in Molecular Neuroscience

Blockade of adenosine A2AR receptors recovers early deficits of memory and plasticity in the triple transgenic mouse model of Alzheimer's disease

Silva, A.C.; Lemos, C.; Gonçalves, F.Q.; Pliássova, A.V.; Machado, N.J.; Silva, H.B.; Canas, P.M.; et al, Neurobiology of Disease. 72 - 81. 117. 2018. http://www.scopus.com/inward/record.url?eid=2-s2.0-85048494541&partnerID=MN8TOARS . 10.1016/j.nbd.2018.05.024 . Neurobiology of Disease

Acyl ghrelin improves cognition, synaptic plasticity deficits and neuroinflammation following amyloid ß (Aß1-40) administration in mice

Santos, V.V.; Stark, R.; Rial, D.; Silva, H.B.; Bayliss, J.A.; Lemus, M.B.; Davies, J.S.; et al, Journal of Neuroendocrinology. 5. 29. 2017. http://www.scopus.com/inward/record.url?eid=2-s2.0-85019741164&partnerID=MN8TOARS . 10.1111/jne.12476 . Journal of Neuroendocrinology

Caffeine Reverts Memory But Not Mood Impairment in a Depression-Prone Mouse Strain with Up-Regulated Adenosine A(2A) Receptor in Hippocampal Glutamate Synapses

Machado, Nuno J.; Simoes, Ana Patricia; Silva, Henrique B.; Ardais, Ana Paula; Kaster, Manuella P.; Garcao, Pedro; Rodrigues, Diana I.; et al, Molecular Neurobiology. 1552 - 1563. 2. 54. 2017. https://publons.com/publon/6042063/ . 10.1007/S12035-016-9774-9 . Molecular Neurobiology

HIGH SUCROSE CONSUMPTION INDUCES MEMORY IMPAIRMENT IN RATS ASSOCIATED WITH ELECTROPHYSIOLOGICAL MODIFICATIONS BUT NOT WITH METABOLIC CHANGES IN THE HIPPOCAMPUS

Lemos, C.; Rial, D.; Goncalves, F. Q.; Pires, J.; Silva, H. B.; Matheus, F. C.; Da Silva, A. C.; et al, Neuroscience. 2016. https://publons.com/publon/792536/ . 10.1016/J.NEUROSCIENCE.2015.12.018 . Neuroscience

"The adenosine facilitation of synaptic plasticity in cortico-striatal synapses is co-operated by the pre-synaptic and astrocytic A2A receptors" Abstracts of the Brazilian Purine Club Meeting

Silva, H., Purinergic Signalling. 343 - 410. 2. 12. 2016. http://dx.doi.org/10.1007/s11302-016-9503-x . 10.1007/s11302-016-9503-x . Purinergic Signalling

Inactivation of adenosine A2A receptors reverses working memory deficits at early stages of Huntington's disease models

Li, Wei; Silva, Henrique B.; Real, Joana; Wang, Yu-Mei; Rial, Daniel; Li, Ping; Payen, Marie-Pierce; et al, Neurobiology of Disease. 2015. https://publons.com/publon/2840189/ . 10.1016/J.NBD.2015.03.030 . Neurobiology of Disease

Caffeine acts through neuronal adenosine A2A receptors to prevent mood and memory dysfunction triggered by chronic stress

Kaster, Manuella P.; Machado, Nuno J.; Silva, Henrique B.; Nunes, Ana; Ardais, Ana Paula; Santana, Magda; Baqi, Younis; et al, Proceedings of the National Academy of Sciences. 2015. https://publons.com/publon/3278967/ . 10.1073/PNAS.1423088112 . Proceedings of the National Academy of Sciences

The role of parkinson's disease-associated receptor GPR37 in the hippocampus: functional interplay with the adenosinergic system.

Lopes JP; Morató X; Souza C; Pinhal C; Machado NJ; Canas PM; Silva HB; et al, Journal of Neurochemistry. 2015. http://europepmc.org/abstract/med/25824528 . 10.1111/jnc.13109 . Journal of Neurochemistry

The effects of different concentrations of the alpha(2)-adrenoceptor agonist medetomidine on basal excitatory synaptic transmission and synaptic plasticity in hippocampal slices of adult mice

Ribeiro, P.O.; Antunes, L.M.; Nunes, C.S.; Silva, H.B.; Cunha, R.A.; Tomé, Â.R., Anesthesia and Analgesia. 1130 - 1137. 5. 120. 2015. http://www.scopus.com/inward/record.url?eid=2-s2.0-84937967119&partnerID=MN8TOARS . 10.1213/ANE.0000000000000636 . Anesthesia and Analgesia

Synaptic and glia involvement in the purinergic control of neurodegenerative diseases

Canas, Paula M.; Rial, Daniel; Simoes, Ana Patricia; Lopes, Joao Pedro; Silva, Henrique B.; Machado, Nuno J.; Queiroz, Francisco; et al, Purinergic Signalling. 2014. https://publons.com/publon/8181585/ . Purinergic Signalling

Clinically relevant concentrations of ketamine mainly affect long-term potentiation rather than basal excitatory synaptic transmission and do not change paired-pulse facilitation in mouse hippocampal slices

Ribeiro, P.O.; Tomé, Â.R.; Silva, H.B.; Cunha, R.A.; Antunes, L.M.; Ribeiro, Patricia O.; Tome, Angelo R.; et al, Brain Research. 10 - 17. 1560. 2014. http://www.scopus.com/inward/record.url?eid=2-s2.0-84898450346&partnerID=MN8TOARS . 10.1016/j.brainres.2014.03.004 . Brain Research

"Synaptic and glia involvement in the purinergic control of neurodegenerative diseases" Abstracts from Purines 2014, an International Conference on Nucleotides, Nucleosides and Nucleobases, held in Bonn, Germany, from July 23¿-27, 2014.

Silva, H., Purinergic Signalling. 657 - 854. 4. 10. 2014. http://dx.doi.org/10.1007/s11302-014-9430-7 . 10.1007/s11302-014-9430-7 . Purinergic Signalling

Behavioral Phenotyping of Parkin-Deficient Mice: Looking for Early Preclinical Features of Parkinson's Disease

Rial, Daniel; Castro, Adalberto A.; Machado, Nuno; Garcao, Pedro; Goncalves, Francisco Q.; Silva, Henrique B.; Tome, Angelo R.; et al, Plos One. 2014. https://publons.com/publon/9695654/ . 10.1371/JOURNAL.PONE.0114216 . Plos One

Inhibition of ecto-5 '-nucleotidase activity facilitates short-term and inhibits long-term plasticity in two different mouse brain regions

Goncalves, Francisco Queiroz; Rial, Daniel; Silva, Henrique; Cunha, Rodrigo, Purinergic Signalling. 2014. https://publons.com/publon/29972398/ . Purinergic Signalling

Hippocampal long-term potentiation in adult mice after recovery from ketamine anesthesia

Ribeiro, Patricia O.; Silva, Henrique B.; Tome, Angelo R.; Cunha, Rodrigo A.; Antunes, Luis M.; Ribeiro PO; Silva HB; et al, Lab Animal. 2014. https://publons.com/publon/33740/ . 10.1038/LABAN.571 . Lab Animal

Effects of medetomidine on basal excitatory synaptic transmission and on synaptic plasticity in mice hippocampal slices

P. Ribeiro; H. B. Silva; R. A. Cunha; L. M. Antunes; Â. R. Tomé, European Journal of Anaesthesiology. 2013. https://publons.com/publon/47015378/ . 10.1097/00003643-201306001-00338 . European Journal of Anaesthesiology

Ketamine affects basal synaptic transmission and long-term potentiation without affect pair-pulse facilitation in hippocampal slices of adult mice

P. Ribeiro; A. Tomé; H. Silva; R. Cunha; L. M. Antunes, European Journal of Anaesthesiology. 2012. https://publons.com/publon/47015288/ . 10.1097/00003643-201206001-00353 . European Journal of Anaesthesiology

Absence of synaptic modifications related to adenosine A1 receptor-mediated control of restraint-stress-induced preconditioning .Purines 2010: Adenine Nucleosides and Nucleotides in Biomedicine

Silva, H., Purinergic Signalling. 1 - 162. S1. 6. 2010. http://dx.doi.org/10.1007/s11302-010-9187-6 . 10.1007/s11302-010-9187-6 . published Purinergic Signalling

Role of The Purinergic Neuromodulation System in Epilepsy

Ângelo R. Tomé; Henrique Silva; Rodrigo A. Cunha, TONEURJ. 64 - 83. 1. 4. 2010. http://dx.doi.org/10.2174/1874082001004010064 . 10.2174/1874082001004010064 . TONEURJ

Voltage-dependent calcium and chloride currents in s17 bone marrow stromal cell line

Silva, H.B.; Medei, E.; Rodrigues, D.C.; Rondinelli, E.; Almeida, N.A.S.; Goldenberg, R.C.S.; Campos De Carvalho, A.C.; et al, Journal of Cellular Physiology. 244 - 251. 1. 223. 2010. http://www.scopus.com/inward/record.url?eid=2-s2.0-75749095604&partnerID=MN8TOARS . 10.1002/jcp.22030 . Journal of Cellular Physiology

Absence of synaptic modifications related to adenosine A1 receptor-mediated control of restraint-stress-induced preconditioning

Silva, Henrique; Tome, Angelo; Kaster, Manuella; Souza, Carolina; Andrade, Geanne; Canas, Paula; Agostinho, Paula; Cunha, Rodrigo, Purinergic Signalling. 2010. https://publons.com/publon/12982137/ . Purinergic Signalling

"Contribution of Endothelium and Smooth Muscle Cells to Vascular Contraction in a Cholesterol-enriched Environment" Proceedings of the British Pharmacological Society meeting. 14-16 December 1994. Abstracts. 185P

Silva, H., British journal of pharmacology. 1995. https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/7773554/?tool=EBI . British journal of pharmacology

"Cholesterol-enriched Diets Modify Vascular Responses in NZW Rabbits" In Proceedings of the 8th Meeting on Adrenergic Mechanisms, Porto, Portugal, 20¿-22 September 1993

Silva, H., Journal of Autonomic Pharmacology. 1 - 1. 1. 14. 1994. http://dx.doi.org/10.1111/j.1474-8673.1994.tb00579.x . 10.1111/j.1474-8673.1994.tb00579.x . published Journal of Autonomic Pharmacology

"Effect of a Cholestrol Enriched-diet on Ghosts and Vascular Wall Membranes in NZW Rabitts" In: XIIth International Congress Of Pharmacology, Montreal - ABSTRACTS/RÉSUMÉS : 26th Winter Meeting

Silva, H., Canadian Journal of Physiology and Pharmacology. Ai - Axxxi. 2. 72. 1994. http://dx.doi.org/10.1139/y94-029 . 10.1139/y94-029 . published Canadian Journal of Physiology and Pharmacology