Publications

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Information about journal articles, updated at 17-12-2023, from platform CIÊNCIAVITAE.

Self-recycling and partially conservative replication of mycobacterial methylmannose polysaccharides

Ana Maranha; Mafalda Costa; Jorge Ripoll-Rozada; José A. Manso; Vanessa Miranda; Vera M. Mendes; Bruno Manadas; et al, Communications Biology. 2023. https://doi.org/10.1038/s42003-023-04448-3 . 10.1038/s42003-023-04448-3 . Communications Biology

Biosynthesis of mycobacterial methylmannose polysaccharides requires a unique 1-O-methyltransferase specific for 3-O-methylated mannosides

Ripoll-Rozada, Jorge; Costa, Mafalda; Manso, José A.; Maranha, Ana; Miranda, Vanessa; Sequeira, André; Ventura, M. Rita; et al, Proceedings of the National Academy of Sciences. 835 - 844. 3. 116. 2019. http://dx.doi.org/10.1073/pnas.1813450116 . 10.1073/pnas.1813450116 . Proceedings of the National Academy of Sciences

Studies of antimicrobial resistance in rare mycobacteria from a nosocomial environment

Pereira, Sónia Gonçalves; Alarico, Susana; Tiago, Igor; Reis, Diogo; Nunes-Costa, Daniela; Cardoso, Olga; Maranha, Ana; Empadinhas, Nuno, BMC Microbiology. 1. 19. 2019. http://dx.doi.org/10.1186/s12866-019-1428-4 . 10.1186/s12866-019-1428-4 . published BMC Microbiology

High-Quality Draft Genome Sequences of Rare Nontuberculous Mycobacteria Isolated from Surfaces of a Hospital

Tiago, Igor; Alarico, Susana; Maranha, Ana; Coelho, Catarina; Pereira, Sónia Gonçalves; Empadinhas, Nuno, Microbiology Resource Announcements. 21. 8. 2019. http://dx.doi.org/10.1128/mra.00496-19 . 10.1128/mra.00496-19 . published Microbiology Resource Announcements

Glucosylglycerate metabolism, bioversatility and mycobacterial survival

Nunes-Costa, Daniela; Maranha, Ana; Costa, Mafalda; Alarico, Susana; Empadinhas, Nuno, Glycobiology. 213 - 227. 1. 27. 2017. http://dx.doi.org/10.1093/glycob/cww132 . 10.1093/glycob/cww132 . Glycobiology

Structure of Mycobacterium thermoresistibile GlgE defines novel conformational states that contribute to the catalytic mechanism

Mendes, Vitor; Blaszczyk, Michal; Maranha, Ana; Empadinhas, Nuno; Blundell, Tom L., Scientific Reports. 17144 - 17144. 17144. 5. 2015. 10.1038/srep17144 . published Scientific Reports

Octanoylation of early intermediates of mycobacterial methylglucose lipopolysaccharides

Maranha, Ana; Moynihan, Patrick J.; Miranda, Vanessa; Lourenço, Eva C.; Nunes-Costa, Daniela; Fraga, Joana S.; José Barbosa Pereira, Pedro; et al, Scientific Reports. 13610 - 13610. 13610. 5. 2015. 10.1038/srep13610 . published Scientific Reports

Structure of mycobacterial maltokinase, the missing link in the essential GlgE-pathway

Fraga, Joana; Maranha, Ana; Mendes, Vitor; Pereira, Pedro José Barbosa; Empadinhas, Nuno; Macedo-Ribeiro, Sandra, Scientific Reports. 8026 - 8026. -. 5. 2015. 10.1038/srep08026#sthash.hjz7R5KL.dpuf . published Scientific Reports

The molecular biology of mycobacterial trehalose in the quest for advanced tuberculosis therapies

Nobre, A.; Alarico, S.; Maranha, A.; Mendes, V.; Empadinhas, N., Microbiology. 1547 - 1570. Pt_8. 160. 2014. 10.1099/mic.0.075895-0 . published Microbiology

Mycobacterium hassiacum recovers from nitrogen starvation with up-regulation of a novel glucosylglycerate hydrolase and depletion of the accumulated glucosylglycerate

Alarico, Susana; Costa, Mafalda; Sousa, Marta S.; Maranha, Ana; Lourenço, Eva C.; Faria, Tiago Q.; Ventura, M. Rita; Empadinhas, Nuno, Scientific Reports. 6766 - 6766. -. 4. 2014. 10.1038/srep06766#sthash.hjz7R5KL.dpuf . published Scientific Reports

Genome Sequence of Mycobacterium hassiacum DSM 44199, a Rare Source of Heat-Stable Mycobacterial Proteins

Tiago, I.; Maranha, A.; Mendes, V.; Alarico, S.; Moynihan, P. J.; Clarke, A. J.; Macedo-Ribeiro, S.; Pereira, P. J. B.; Empadinhas, N., Journal of Bacteriology. 7010 - 7011. 24. 194. 2012. 10.1128/JB.01880-12 . published Journal of Bacteriology

Biosynthesis of mycobacterial methylglucose lipopolysaccharides

Mendes, Vitor; Maranha, Ana; Alarico, Susana; Empadinhas, Nuno, Natural Product Reports. 834 - 834. 8. 29. 2012. 10.1039/C2NP20014G . published Natural Product Reports

Mycobacterium tuberculosis Rv2419c, the missing glucosyl-3-phosphoglycerate phosphatase for the second step in methylglucose lipopolysaccharide biosynthesis

Mendes, Vítor; Maranha, Ana; Alarico, Susana; da Costa, Milton S.; Empadinhas, Nuno, Scientific Reports. 177 - 177. -. 1. 2011. 10.1038/srep00177 . published Scientific Reports

Biochemical characterization of the maltokinase from Mycobacterium bovis BCG

Mendes, Vítor; Maranha, Ana; Lamosa, Pedro; da Costa, Milton S.; Empadinhas, Nuno, BMC Biochemistry. 21 - 21. 1. 11. 2010. 10.1186/1471-2091-11-21#sthash.hjz7R5KL.dpuf . published BMC Biochemistry

All projects

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Information of exclusive responsibility of the researcher 17-12-2023 , from platform CIÊNCIAVITAE.

2023 - 2026

Validation of bacterial-derived anti-inflammatory mediators in gut-first PD

CP code: SC01 (249.823 £)

Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: Cure Parkinson's

2023/04 -

AMRFight - Exploring bacterial interactions to find novel molecules to combat the antimicrobial resistance catastrophe

(2022.06809.PTDC

Principal investigator

2022/01 -

The microbiome-miRNAs axis in Parkinson's disease: implications of mitochondria mediated inflammatory response (as co-PI).

EXPL/MED-NEU/1515/2021

Supervisor

2022 -

NTMENACE: Nontuberculous mycobacteria from drinking water: beyond the lung disease epidemic

PTDC/BIA-MIC/0122/2021

Researcher

2020/11/01 -

Project Health in Knowledge - A Saúde no Saber – coordinated by the CNC Science Communication office

-

Researcher

Centro de Inovação em Biomedicina e Biotecnologia (CIBB)

Funders: Ciência Viva

2018 - 2021

POLYREP: An intriguing mycobacterial polysaccharide: recycling, replication and beyond

PTDC/BTM-TEC/29221/2017

Researcher

Centro de Inovação em Biomedicina e Biotecnologia (CIBB)

Funders: Fundação para a Ciência e a Tecnologia, I.P.

2018 -

Award Thomé Villar/Boehringer Ingelheim, Portuguese Society of Pneumology, 1st Prize. Prevalência e variabilidade genética de micobactérias não-tuberculosas em ambiente doméstico (Prevalence and genetic variability of non-tuberculous mycobacteria in domestic environment).

Award Thomé Villar/Boehringer Ingelheim, Portuguese Society of Pneumology, 1st Prize 2018

Post-doc

Funders: Sociedade Portuguesa de Pneumologia

2017 - 2019

Microcare: Microbiome of diabetic ulcers: early diagnosis, prognosis and therapy.

, FIS-FIS-2015-01_DIA_20150630-144

Post-doc

Centro de Inovação em Biomedicina e Biotecnologia (CIBB)

Funders: Infarmed Autoridade Nacional do Medicamento e Produtos de Saúde IP

2014 - 2015

Produção e comercialização de compostos microbianos essenciais para investigação. (Production and commercialization of microbial compounds essential for research).

Programa Estratégico InovC Mais Centro/CCDRC/QREN

Researcher

Centro de Inovação em Biomedicina e Biotecnologia (CIBB)

2013/07 - 2015/09

Biosynthesis of rare methylmannose polysaccharides in nontuberculous mycobacteria

128742

Researcher

Centro de Inovação em Biomedicina e Biotecnologia (CIBB)

Funders: Fundação para a Ciência e a Tecnologia, I.P.

2012 - 2014

Unravelling the early steps in the biosynthesis of the mycobacterial MGLP

120123

Researcher

Centro de Inovação em Biomedicina e Biotecnologia (CIBB)

Funders: Koeki Zaidan Hojin Mizutani Toshitsu Kagaku Shinko Zaidan

2011/04/01 - 2014

The enigmatic mycobacterial maltokinase

info:eu-repo/grantAgreement/FCT/5876-PPCDTI/112459/PT

Researcher

Centro de Inovação em Biomedicina e Biotecnologia (CIBB)

Funders: Fundação para a Ciência e a Tecnologia

2011/01 - 2014/06

Pathway for the synthesis of the mycobacterial MGLP. Biochemical and structural characterization of the key enzymes

Provided by PTCRIS: 110523

Other

Centro de Inovação em Biomedicina e Biotecnologia (CIBB)

Funders: Fundação para a Ciência e a Tecnologia, I.P.

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