Anthony Joseph Burke

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Overview

Anthony Burke is an associate professor with aggregation at the Faculty of Pharmacy University of Coimbra and a Chemistry Europe fellow. He has a PhD from University college Dublin and conducted post-doctoral research in Oxford (Dyson Perrins Lab) and ITQB, Portugal. He moved to the University of Coimbra in early 2022, from the chemistry department, University of Evora. He has over 130 works (includes books, book chapters, papers, patents, editorials and oral presentations etc) and has coordinated many projects. He has a successful track record in drug discovery in the area of Alzheimer's disease and a strong interest in sustainable catalytic processes for making new drug molecules. Other areas of interest include; polymer synthesis and NMR. He has trained over 90 students (from Post-docs to research undergrads). He founded Chiratecnics (www.chirarecnics.com) in 2009 and is the chairman of the International Symposium on Synthesis and Catalysis series (ISySyCat15, ISySyCat17, ISySyCat19 and ISySyCat21). He is currently an editor at Open Chemistry (De Gruyter).

Affiliation

Faculty of Pharmacy, University of Coimbra.

Publications

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Information about journal articles, updated at 18-04-2024, from platform CIÊNCIAVITAE.

Accessing Medicinally Relevant O -Benzofused Heterocycles through C-X Activation: Recent Trends

Moutayakine, Amina; Burke, Anthony J., European Journal of Organic Chemistry. 2022. http://dx.doi.org/10.1002/ejoc.202101465 . 10.1002/ejoc.202101465 . European Journal of Organic Chemistry

Transformation of a Chiral Glycolic Acid to an Isoaurone: Stereochemical Assignment of a Benzilic Acid Rearrangment Product

Burke, Anthony J.; Teixeira, Carla S. S.; Sousa, Sergio F., Asian Journal of Organic Chemistry. 2022. http://dx.doi.org/10.1002/ajoc.202100692 . 10.1002/ajoc.202100692 . Asian Journal of Organic Chemistry

Engaging Isatins in Multicomponent Reactions (MCRs) – Easy Access to Structural Diversity

Brandão, Pedro; Marques, Carolina S.; Carreiro, Elisabete P.; Pineiro, M.; Burke, Anthony J., The Chemical Record. 1 - 115. 21. 2021. http://dx.doi.org/10.1002/tcr.202000167 . 10.1002/tcr.202000167 . published The Chemical Record

Novel 1,2,3-triazole epicinchonas: Transitioning from organocatalysis to biological activities

Barrulas, Pedro; Carreiro, Elisabete P.; Veiros, Luis F.; Amorim, Ana C.; Gut, Giri; Rosenthal, Philip J.; López, Óscar; et al, Synthetic Communications. 2954 - 2974. 19. 51. 2021. http://dx.doi.org/10.1080/00397911.2021.1948575 . 10.1080/00397911.2021.1948575 . Synthetic Communications

Recent Advances in Asymmetric Hydrogenation Catalysis Utilizing Spiro and Other Rigid C-Stereogenic Phosphine Ligands

Burke, Anthony J.; Federsel, Hans-Jürgen; Hermann, Gesine J., The Journal of Organic Chemistry. 2021. http://dx.doi.org/10.1021/acs.joc.1c01571 . 10.1021/acs.joc.1c01571 . The Journal of Organic Chemistry

Petasis adducts of tryptanthrin – synthesis, biological activity evaluation and druglikeness assessment

Brandão, Pedro; Marques, Carolina; Pinto, Eugénia; Pineiro, Marta; Burke, Anthony J., New Journal of Chemistry. 14633 - 14649. 32. 45. 2021. http://dx.doi.org/10.1039/d1nj02079j . 10.1039/d1nj02079j . New Journal of Chemistry

Ugi Adducts of Isatin as Promising Antiproliferative Agents with Druglike Properties

Brandão, Pedro; Puerta, Adrián; Padrón, José M.; Kuznetsov, Maxim L.; Burke, Anthony J.; Pineiro, Marta, Asian Journal of Organic Chemistry. 3434 - 3455. 12. 10. 2021. http://dx.doi.org/10.1002/ajoc.202100684 . 10.1002/ajoc.202100684 . Asian Journal of Organic Chemistry

Ugi Reaction Synthesis of Oxindole–Lactam Hybrids as Selective Butyrylcholinesterase Inhibitors

Brandão, Pedro; López, Óscar; Leitzbach, Luisa; Stark, Holger; Fernández-Bolaños, José G.; Burke, Anthony J.; Pineiro, Marta, ACS Medicinal Chemistry Letters. 1718 - 1725. 11. 12. 2021. http://dx.doi.org/10.1021/acsmedchemlett.1c00344 . 10.1021/acsmedchemlett.1c00344 . ACS Medicinal Chemistry Letters

Seeking a Fast Screening Method of the Varietal Origin of Olive Oil: The Usefulness of an NMR-Based Approach

Cabrita, Maria João; Pires, Arona; Burke, Anthony J.; Garcia, Raquel, Foods. 2. 10. 2021. http://dx.doi.org/10.3390/foods10020399 . 10.3390/foods10020399 . Foods

Stereoselective Benzilic Acid Rearrangements: New Advances on an Old Story

Burke, Anthony; Maoutakakine, Amina, Chemical Communications. 2021. http://dx.doi.org/10.1039/d0cc07905g . 10.1039/d0cc07905g . in press Chemical Communications

The application of isatin-based multicomponent-reactions in the quest for new bioactive and druglike molecules

Brandão, Pedro; Marques, Carolina; Burke, Anthony J.; Pineiro, Marta, European Journal of Medicinal Chemistry. 211. 2021. http://dx.doi.org/10.1016/j.ejmech.2020.113102 . 10.1016/j.ejmech.2020.113102 . European Journal of Medicinal Chemistry

Asymmetric Neber Reaction in the Synthesis of Chiral 2-(Tetrazol-5-yl)-2H-Azirines

Cláudia Alves; Carla Grosso; Pedro Barrulas; José A. Paixão; Ana L. Cardoso; Anthony J. Burke; Américo Lemos; Teresa M. V. D. Pinho e Melo, Synlett. 2020. https://doi.org/10.1055/s-0039-1691533 . 10.1055/s-0039-1691533 . Synlett

Synthesis of Novel 1,2,3-Triazole-Dihydropyrimidinone Hybrids Using Multicomponent 1,3-Dipolar Cycloaddition (Click)–Biginelli Reactions: Anticancer Activity

Elisabete P. Carreiro; Ana M. Sena; Adrián Puerta; José M. Padrón; Anthony J. Burke, Synlett. 2020. https://doi.org/10.1055/s-0039-1690781 . 10.1055/s-0039-1690781 . Synlett

Accessing new 5-a-(3,3-Disubstituted Oxindole) -Benzylamine Derivatives from Isatin: Stereoselective Organocatalytic Three Component Petasis Reaction

BURKE, Anthony; Marques, Carolina Silva, 2020. under revision

A decade of Indium-catalyzed multicomponent reactions (MCRs)

BURKE, Anthony; Brandão, Pedro; Pineiro, Marta, The Role of Social Environment and Personality Validation of Antecedents of Intercultural Communication Competence and its Effects on Customer Satisfaction. 2020. submitted The Role of Social Environment and Personality Validation of Antecedents of Intercultural Communication Competence and its Effects on Customer Satisfaction

A Decade of Indium-Catalyzed Multicomponent Reactions (MCRs)

Brandão, Pedro; Burke, Anthony J.; Pineiro, Marta, European Journal of Organic Chemistry. 5501 - 5513. 2020. http://dx.doi.org/10.1002/ejoc.202000596 . 10.1002/ejoc.202000596 . European Journal of Organic Chemistry

Reações Multicomponente – Uma Ferramenta Valiosa na Descoberta e Produção de Fármacos

Marta Piñeiro; Pedro Brandão; Anthony J. Burke, Boletim da Sociedade Portuguesa de Química. 2020. http://dx.doi.org/10.52590/m3.p694.a30002331 . 10.52590/m3.p694.a30002331 . Boletim da Sociedade Portuguesa de Química

Reações Multicomponente – uma ferramenta valiosa na descoberta e produção de fármacos

BURKE, Anthony; Pineiro, Marta; Brandão, Pedro, Bulletin Portugese Chemical Society. 2020. https://www.spq.pt/files/files/BSPQ/20.pdf . in press Bulletin Portugese Chemical Society

Ambipolar Pentacyclic Diamides with Interesting Electrochemical and Optoelectronic Properties

BURKE, Anthony; Jorge Morgado; Carolina S. Marques; JP Prates Ramalho; Luís A Branco, Chemical Communications. 2020. https://doi.org/10.1039/D0CC04629A . in press Chemical Communications

N-1,2,3-Triazole-Isatin Derivatives for Cholinesterase and ¿-Amyloid Aggregation Inhibition: A Comprehensive Bioassay Study

BURKE, Anthony; Marques, Carolina Silva; Carreiro, Elisabete, 2020. https://www.sciencedirect.com/science/article/abs/pii/S0045206820301954?via%3Dihub .

PALLADIUM CATALYSED CYCLIZATIONS FOR N-HETEROCYCLE SYNTHESIS: RECENT DEVELOPMENTS

BURKE, Anthony; Moutayakine Amina, Chimica Oggi/Chemistry Today, . 38. 2020. https://www.teknoscienze.com/tks_article/palladium-catalysed-cyclizations-for-n-heterocycle-synthesis-recent-developments/ . published Chimica Oggi/Chemistry Today,

Palladium Catalyzed Cyclizations for Heterocycle Synthesis: Recent Developments

BURKE, Anthony; Moutayakine Amina, Chimica Oggi. 28 - 34. 5. 38. 2020. https://www.teknoscienze.com/tks_article/palladium-catalysed-cyclizations-for-n-heterocycle-synthesis-recent-developments/ . published Chimica Oggi

Accessing new 5-a-(3,3-Disubstituted Oxindole) -Benzylamine Derivatives from Isatin: Stereoselective Organocatalytic Three Component Petasis Reaction

BURKE, Anthony; mARQUES cAROLINA SILVA, European Journal of Organic Chemistry. 2020. submitted European Journal of Organic Chemistry

Assessment of the triacylglycerol fraction of olive oil by 1D-NMR spectroscopy: exploring the usefulness of DEPT tool on the peak assignments of <sup>13</sup>C NMR spectra

Garcia, R.; Pires, A.; Martins, N.; Carvalho, T.; Burke, A.J.; Cabrita, M.J., European Food Research and Technology. 2479 - 2488. 11. 245. 2019. http://www.scopus.com/inward/record.url?eid=2-s2.0-85073669221&partnerID=MN8TOARS . 10.1007/s00217-019-03359-0 . European Food Research and Technology

Catalytic Ugi Reactions: Current Advances, Future Challenges, Part 2

BURKE, Anthony; Brandão Pedro, Chimica Oggi/Chemistry Today, Special edition Biocatalysis & Catalysis. 4. 37. 2019. published Chimica Oggi/Chemistry Today, Special edition Biocatalysis & Catalysis

Catalytic Ugi Reactions: Current Advances, Future Challenges, Part 1

BURKE, Anthony; Brandão Pedro, Chimica Oggi/Chemistry Today, Special edition Biocatalysis & Catalysis. 4. 37. 2019. published Chimica Oggi/Chemistry Today, Special edition Biocatalysis & Catalysis

Asymmetric Neber Reaction in the Synthesis of Chiral 2-(Tetrazol-5-yl)-2H-Azirines

Alves, Cláudia; Grosso, Carla; Barrulas, Pedro; Paixão, José A.; Cardoso, Ana L.; Burke, Anthony J.; Lemos, Américo; Pinho e Melo, Teresa M. V. D., Synlett. 553 - 558. 06. 31. 2019. http://dx.doi.org/10.1055/s-0039-1691533 . 10.1055/s-0039-1691533 . Synlett

Metal-Catalyzed Routes to Dibenzodiazepines (DBDAs) and Structural Analogues: Recent Advances

Anthony J. Burke, 2018. https://onlinelibrary.wiley.com/doi/epdf/10.1002/ejoc.201801304 . https://onlinelibrary.wiley.com/doi/epdf/10.1002/ejoc.201801304 .

Pd-Catalyzed One-Pot Borylation/Intramolecular Asymmetric Arylation on a-Ketiminoamides: Innovative Approach to Chiral 3-Amino-2-oxindoles

List, Benjamin, 2018. https://www.thieme-connect.com/products/ejournals/abstract/10.1055/s-0036-1590940 . https://www.thieme-connect.com/products/ejournals/abstract/10.1055/s-0036-1590940 .

Novel Palladium-Catalyzed Intramolecular Addition of Aryl Bromides to Aldehydes as Key to the Synthesis of 3,3-Dimethylchroman-4-ones and 3,3-Dimethylchroman-4-ols

Hugo Viana; Carolina S. Marques; Camille A. Correia; Kerry Gilmore; Luís Galvão; Letícia Vieira; Peter H. Seeberger; Anthony J. Burke, ChemistrySelect. 11333 - 11338. 40. 3. 2018. https://doi.org/10.1002/slct.201802889 . 10.1002/slct.201802889 . ChemistrySelect

A photoswitchable “host-guest” approach for the selective enrichment of dimethoate from olive oil

Garcia, R.; Carreiro, E.P.; Prates Ramalho, J.P.; Burke, A.J.; Lima, J.C.; Gomes da Silva, M.D.R.; Costa Freitas, A.M.; Cabrita, M.J., Analytica Chimica Acta. 60 - 69. 1035. 2018. http://www.scopus.com/inward/record.url?eid=2-s2.0-85049811096&partnerID=MN8TOARS . 10.1016/j.aca.2018.07.017 . Analytica Chimica Acta

Virtual Collection of Portuguese Catalysis

Armando J. L. Pombeiro; Anthony J. Burke, ChemCatChem. 2712 - 2716. 13. 10. 2018. https://doi.org/10.1002/cctc.201801006 . 10.1002/cctc.201801006 . ChemCatChem

Novel Palladium-Catalyzed Intramolecular Addition of Aryl Bromides to Aldehydes as Key to the Synthesis of 3,3-Dimethylchroman-4-ones and 3,3-Dimethylchroman-4-ols

Astruc, Didier, 2018. https://onlinelibrary.wiley.com/doi/pdf/10.1002/slct.201802889 . https://onlinelibrary.wiley.com/doi/pdf/10.1002/slct.201802889 .

A magnetic controllable tool for the selective enrichment of dimethoate from olive oil samples: a responsive molecular imprinting-based approach

Garcia, Raquel; Carreiro, Elisabete; Prates Ramalho, João Paulo; Burke, Anthony J.; Lima, Joao C.; Gomes da Silva, Marco; Costa Freitas, Ana Maria; Cabrita, Maria João, 2018. http://hdl.handle.net/10174/23827 .

Anti-proliferative effects of novel hydroxyamidaes and triazoles

Anthony J. Burke; Carreiro, Elisabete P.; Antunes, Célia M, 2018. http://www.sciencedirect.com/science/article/pii/S1871678415001776 .

In Silico, NMR and Pharmacological Evaluation of an Hydroxyoxindole Cholinesterase Inhibitor

Patrícia Bacalhau; Luís Fernandes; M. Rosário Martins; Fátima Candeias; Elisabete P. Carreiro; Óscar López; A. Teresa Caldeira; et al, Bioorganic & Medicinal Chemistry. 2018. https://doi.org/10.1016/j.bmc.2018.12.007 . 10.1016/j.bmc.2018.12.007 . Bioorganic & Medicinal Chemistry

Metal-Catalyzed Routes to Dibenzodiazepines (DBDAs) and Structural Analogues: Recent Advances

Burke, Anthony J; Marques, Carolina M, 2017. http://hdl.handle.net/10174/22612 .

Design, Synthesis and Bioassays of 3-Substituted-3-Hydroxyoxindoles: Donepezil Analogues for Cholinesterase Inhibition

Anthony J. Burke; Marques, Carolina Silva, 2016. http://onlinelibrary.wiley.com/doi/10.1002/slct.201600932/full#ref . http://onlinelibrary.wiley.com/doi/10.1002/slct.201600932/full#ref .

Sequential alcohol oxidation/putative homo Claisen–Tishchenko-type reaction to give esters: a key process in accessing novel biologically active lactone macrocycles

Viana, Hugo; Carreiro, Elisabete P.; Goth, Albertino; Bacalhau, Patrícia; Caldeira, Ana Teresa; Martins, Maria do Rosário; Burke, Anthony Joseph, RSC Advances. 63214 - 63223. 68. 6. 2016. http://dx.doi.org/10.1039/c6ra07547a . 10.1039/c6ra07547a . published RSC Advances

Insights into (S)-rivastigmine inhibition of butyrylcholinesterase (BuChE): Molecular docking and saturation transfer difference NMR (STD-NMR)

Bacalhau, Patrícia; San Juan, Amor A.; Goth, Albertino; Caldeira, A. Teresa; Martins, Rosário; Burke, Anthony J., Bioorganic Chemistry. 105 - 109. 67. 2016. http://dx.doi.org/10.1016/j.bioorg.2016.06.002 . 10.1016/j.bioorg.2016.06.002 . Bioorganic Chemistry

Novel hydroxyamides and amides containing D-glucopyranose or D-fructose units: biological assays in MCF-7 and MDST8 cell lines

Carreiro, Elisabete P.; Costa, Ana Rodrigues; Cordeiro, Maria M.; Martins, Rute; Pires, Tiago O.; Saraiva, Mafalda; Antunes, Célia M.; Burke, Anthony J., 2016. http://www.sciencedirect.com/science/article/pii/S0960894X15303498 . published

Stereoselective Metal-Free Reduction of Chiral Imines in Batch and Flow Mode: A Convenient Strategy for the Synthesis of Chiral Active Pharmaceutical Ingredients

BURKE, Anthony, 2016. https://chemistry-europe.onlinelibrary.wiley.com/doi/abs/10.1002/ejoc.201601268 . http://onlinelibrary.wiley.com/doi/10.1002/ejoc.201601268/epdf . published

Dual layer solid phase extraction based on molecular imprinting technology: Seeking a route to enhance selectivity for trace analysis of pesticide residues in olive oil

Garcia, Raquel; Carreiro, Elisabete; Nunes, José; Gomes da Silva, Marco; Costa Freitas, Ana Maria; Burke, Anthony; Cabrita, Maria João, 2016. http://hdl.handle.net/10174/18691 .

Design and development of molecularly imprinted polymers for the selective extraction of deltamethrin in olive oil: An integrated computational-assisted approach

Martins, Nuno; Carreiro, Elisabete; Locati, Abel; Ramalho, João Prates; Cabrita, Maria João; Burke, Anthony J.; Garcia, Raquel, 2015. https://www.sciencedirect.com/science/article/abs/pii/S0021967315009760 .

New click-chemistry methods for 1,2,3-triazoles synthesis: recent advances and applications

Totobenazara, Jane; Burke, Anthony J., Tetrahedron Letters. 2853 - 2859. 22. 56. 2015. http://dx.doi.org/10.1016/j.tetlet.2015.03.136 . 10.1016/j.tetlet.2015.03.136 . Tetrahedron Letters

Development of a selective sorbent for the solid-phase extraction of terbuthylazine in olive oil samples: A molecular imprinting strategy

Garcia, Raquel; Martins, Nuno; Carreiro, Elisabete; Simões, Marco; Ribeiro Carrot, Maria ML; Carrot, Peter J.M..; Burke, Anthony; Cabrita, Maria Joao, 2015. https://onlinelibrary.wiley.com/doi/full/10.1002/jssc.201401263 . published

A catalytic route to dibenzodiazepines involving Buchwald-Hartwig coupling: reaction scope and mechanistic consideration

BURKE, Anthony; Peixoto, Daniela Alexandra Silva, 2015. https://pubs.rsc.org/en/content/articlelanding/2015/ra/c5ra19599c#!divAbstract . published

Transition-metal-catalyzed intramolecular cyclization of amido(hetero)arylboronic acid aldehydes to isoquinolinones and derivatives

Marques, C. S.; Peixoto, D.; Burke, A. J., RSC Advances. 20108 - 20114. 26. 5. 2015. http://dx.doi.org/10.1039/c5ra00404g . 10.1039/c5ra00404g . RSC Advances

Palladium Catalyzed Sequential Imine Phenylation/Suzuki-Miyaura Couplings: Synthesis of ¿-(biarylyl)benzylamines,

Marques, Carolina S.; Locati, Abel; Prates Ramalho, J.P.; Burke, Anthony J., 2015. http://hdl.handle.net/10174/16941 .

An emerging approach for the targeting analysis of dimethoate in olive oil: The role of molecularly imprinted polymers based on photo-iniferter induced “living” radical polymerization

Martins, Nuno; Simões, Marco; Carreiro, Elisabete; Cabrita, Maria Joao; Burke, Anthony; Garcia, Raquel, 2015. https://www.sciencedirect.com/science/article/abs/pii/S1381514814002247 . published

Asymmetric catalytic arylation of ethyl glyoxylate using organoboron reagents and Rh(i)–phosphane and phosphane–phosphite catalysts

Burke, Anthony; Marques, Carolina; Schmalz, Hans-Günther; Mehmet, Dindaroglu, 2014. https://pubs.rsc.org/en/content/articlelanding/2014/ra/c3ra47000h#!divAbstract .

Tailor-made molecularly imprinted polymers for dimethoate and deltamethrin recognition: synthesis, characterization and chromatographic evaluation

Simões, Marco; Martins, Nuno; Cabrita, Maria João; Burke, Anthony J.; Garcia, Raquel, 2014. https://link.springer.com/article/10.1007/s10965-014-0368-9 .

3-Hydroxypyrrolidine and (3,4)-Dihydroxypyrrolidine Derivatives: Inhibition of rat intestinal ¿-Glucosidase

BURKE, Anthony; Carreiro, Elisabete P.; Guedes, Rita C.; Antunes, Célia M.; Costa, Ana R, 2014. https://www.sciencedirect.com/science/article/pii/S0045206814000315 . published

Location of Repository Antioxidant and Antimicrobial Activities of Arylamide-Acetals derivates: Potential Drugs for Neurodegenerative Diseases

BURKE, Anthony; Caldeira, A. Teresa; Martins, M. Rosário; Marques, Carolina Silva; Peixoto, Daniela Alexandra Silva, 2014. http://hdl.handle.net/10174/13091 .

Cinchona-Derived Picolinamides: Effective Organocatalysts for Stereoselective Imine Hydrosilylation

BURKE, Anthony; Barrulas, Pedro Miguel Cambeiro, 2014. https://chemistry-europe.onlinelibrary.wiley.com/doi/abs/10.1002/ejoc.201403180 .

Synthesis of novel cinchona-amino acid hybrid organocatalysts for asymmetric catalysis

BURKE, Anthony; Barrulas, Pedro Miguel Cambeiro; Benaglia Maurizio, 2014. https://www.sciencedirect.com/science/article/abs/pii/S0957416614002225 .

Novel Pyrrolidinediol ¿-glucosidase inhibitors: Synthesis, Screening and Molecular Modelling

BURKE, Anthony; Carreiro, Elisabete P.; Guedes, Rita C.; A. Teresa Caldeira, 2013. https://www.sciencedirect.com/science/article/pii/S096808961300059X .

TARTROL-derived chiral phosphine–phosphite ligands and their performance in enantioselective Cu-catalyzed 1,4-addition reaction

BURKE, Anthony; Marques, Carolina Silva, Polyhedron. 2013. https://www.sciencedirect.com/science/article/abs/pii/S0957416613001675 . published Polyhedron

Enantioselective catalytic synthesis of ethyl mandelate derivatives using Rh(I)–NHC catalysts and organoboron reagents

BURKE, Anthony; Marques, Carolina Silva, 2013. https://www.sciencedirect.com/science/article/abs/pii/S0957416613001705 .

Expeditious and novel synthesis of a-hydroxyesters via rhodium–NHC catalyzed arylation of ethyl glyoxalate

Burke, Anthony; Marques, Carolina, 2012. https://www.sciencedirect.com/science/article/pii/S0040402012008769 .

Covalent and Non-Covalent Immobilization of Arylid-BOX and Arylid-BOX Derivative Ligands: Evaluation in the Catalytic Asymmetric Cyclopropanation of Styrenes

Burke, Anthony; Carreiro, Elisabete; Moura, Nuno M. M., 2012. http://onlinelibrary.wiley.com/doi/10.1002/ejoc.201100781/pdf . http://onlinelibrary.wiley.com/doi/10.1002/ejoc.201100781/pdf .

Chiral Diphosphane- and NHC-Containing Ruthenium Catalysts for the Catalytic Asymmetric Arylation of Aldimines with Organoboron Reagents

Burke, Anthony; Marques, Carolina, 2012. http://onlinelibrary.wiley.com/doi/10.1002/ejoc.201200556/pdf . http://onlinelibrary.wiley.com/doi/10.1002/ejoc.201200556/pdf .

Advances in the Catalytic Asymmetric Arylation of Imines using Organoboron Reagents: An Approach to Chiral Arylamines

BURKE, Anthony; Marques, Carolina Silva, 2011. https://chemistry-europe.onlinelibrary.wiley.com/doi/pdf/10.1002/cctc.201000369 .

Evaluation of phosphinoamidoester-derived Pd catalysts in the asymmetric allylic alkylation reaction: Theoretical studies and mechanistic insights

BURKE, Anthony; Marinho, Vanda Raquel Delgado; Ramalho, J. P. Prates; Rodrigues, Ana Isabel, 2011. https://onlinelibrary.wiley.com/doi/full/10.1002/chir.20936 .

Chiral monooxazolines as modular copper(I)-heterocomplex building blocks: investigations on the catalytic asymmetric cyclopropanation of alkenes

Prates Ramalho, João Paulo; Carreiro, Elisabete; Burke, Anthony, 2011. https://pdf.sciencedirectassets.com/271372/1-s2.0-S0040402011X00224/1-s2.0-S0040402011005849/main.pdf?X-Amz-Date=20200416T121025Z&X-Amz-Algorithm=AWS4-HMAC-SHA256&X-Amz-Signature=a2c219d5184d61f177bf96ed7045a7bfacf28e9efb7728131b7d277ff37129db&X-Amz-Crede .

ChemInform Abstract: Asymmetric Synthesis of the N-Terminal Component of Microginin: (2S,3R) -3-Amino-2-Hydroxydecanoic Acid, Its (2R,3R)-Epimer and (3R)-3- Aminodecanoic Acid.

BUNNAGE, M. E.; BURKE, A. J.; DAVIES, S. G.; GOODWIN, C. J., ChemInform. no - no. 27. 26. 2010. http://dx.doi.org/10.1002/chin.199527250 . 10.1002/chin.199527250 . ChemInform

Recent Multiple Transition Metal Catalysed Single-Pot Reactions

Burke, Anthony; Marinho, Vanda; Furtado, Olivia, Current Organic Synthesis. 94 - 119. 2. 7. 2010. http://dx.doi.org/10.2174/157017910790820283 . 10.2174/157017910790820283 . Current Organic Synthesis

ChemInform Abstract: Catalytic Enantioselective Addition of Phenylboronic Acid and Phenylboroxine to N-Tosylimines: PdII and RhI Catalysis.

Marques, Carolina S.; Burke, Anthony J., ChemInform. no - no. 30. 41. 2010. http://dx.doi.org/10.1002/chin.201030022 . 10.1002/chin.201030022 . ChemInform

ChemInform Abstract: Asymmetric Synthesis of (2S,3S)- and (2R,3S)-2,3-Diaminobutanoic Acids, Non-Protein Amino-Acid Diastereomers Found in a Number of Peptide Antibiotics.

BURKE, A. J.; DAVIES, S. G.; HEDGECOCK, C. J. R., ChemInform. no - no. 49. 27. 2010. http://dx.doi.org/10.1002/chin.199649221 . 10.1002/chin.199649221 . ChemInform

The benzilic ester rearrangement: synthesis of labelled compounds and theoretical studies

Marques, Carolina S.; Ramalho, J. P. Prates; Burke, Anthony J., 2009. https://onlinelibrary.wiley.com/doi/abs/10.1002/poc.1509 .

Application of Walphos Ligand in the Pd(0)-Catalyzed Asymmetric Allylic Alkylation Reaction

Marinho, Vanda R.; Burke, Anthony J., Synthetic Communications. 4423 - 4428. 24. 39. 2009. http://dx.doi.org/10.1080/00397910902906578 . 10.1080/00397910902906578 . Synthetic Communications

The benzilic ester rearrangement: synthesis of labelled compounds and theoretical studies

Marques, Carolina S.; Ramalho, J. P. Prates; Burke, Anthony J., Journal of Physical Organic Chemistry. 735 - 739. 8. 22. 2009. http://dx.doi.org/10.1002/poc.1509 . 10.1002/poc.1509 . Journal of Physical Organic Chemistry

A Comparison of (R,R)-Me-DUPHOS and (R,R)-DUPHOS-iPr Ligands in the Pd0-Catalysed Asymmetric Allylic Alkylation Reaction: Stereochemical and Kinetic Considerations

Marinho, Vanda Raquel; Ramalho, J. P. Prates; Rodrigues, Ana I.; Burke, Anthony J., 2009. https://chemistry-europe.onlinelibrary.wiley.com/doi/abs/10.1002/ejoc.200900649 .

Arylid-OX and Arylid-BOX derived catalysts: applications in catalytic asymmetric cyclopropanation

Carreiro, Elisabete Palma; Burke, Anthony J.; Ramalho, J.P. Prates; Rodrigues, Ana Isabel, Tetrahedron: Asymmetry. 1272 - 1278. 11. 20. 2009. http://dx.doi.org/10.1016/j.tetasy.2009.04.005 . 10.1016/j.tetasy.2009.04.005 . Tetrahedron: Asymmetry

Novel chiral P,O-ligands for homogeneous Pd(0) catalysed asymmetric allylic alkylation reactions

Marinho, Vanda Raquel; Rodrigues, Ana Isabel; Burke, Anthony J., Tetrahedron: Asymmetry. 454 - 458. 4. 19. 2008. http://dx.doi.org/10.1016/j.tetasy.2008.01.024 . 10.1016/j.tetasy.2008.01.024 . Tetrahedron: Asymmetry

New Route to N-Alkylated trans-Pyrrolidine Diols from 2,2,3,3-Tetramethoxybutane-Protected Dimethyl Tartrate

Graça Martins, J.; Cambeiro Barrulas, P.; Marques, Carolina S.; Burke, Anthony J., Synthetic Communications. 1365 - 1374. 9. 38. 2008. http://dx.doi.org/10.1080/00397910801916520 . 10.1080/00397910801916520 . Synthetic Communications

Chiral oxoperoxomolybdenum(VI) complexes for enantioselective olefin epoxidation: Some mechanistic and stereochemical reflections

Burke, Anthony J., Coordination Chemistry Reviews. 170 - 175. 1-2. 252. 2008. http://dx.doi.org/10.1016/j.ccr.2007.05.002 . 10.1016/j.ccr.2007.05.002 . Coordination Chemistry Reviews

Palladium catalysed enantioselective asymmetric allylic alkylations using the Berens’ DIOP analogue

Marques, Carolina S.; Burke, Anthony J., Tetrahedron: Asymmetry. 1804 - 1808. 15. 18. 2007. http://dx.doi.org/10.1016/j.tetasy.2007.07.004 . 10.1016/j.tetasy.2007.07.004 . Tetrahedron: Asymmetry

Mechanistic and Synthetic Aspects of the Benzilic Acid and Ester Rearrangements

Burke, Anthony; Marques, C., Mini-Reviews in Organic Chemistry. 310 - 316. 4. 4. 2007. http://dx.doi.org/10.2174/157019307782411707 . 10.2174/157019307782411707 . Mini-Reviews in Organic Chemistry

The catalytic tandem oxidation/benzilic ester rearrangement (BER): insights into reaction mechanism and stereoselectivity

Marques, Carolina Silva; Moura, Nuno M.M.; Burke, Anthony J.; Furtado, Olívia R., Tetrahedron Letters. 7957 - 7960. 45. 48. 2007. http://dx.doi.org/10.1016/j.tetlet.2007.09.066 . 10.1016/j.tetlet.2007.09.066 . Tetrahedron Letters

Palladium catalysed enantioselective asymmetric allylic alkylations using the Berens’ DIOP analogue

Marques, Carolina S.; Burke, Anthony J., Tetrahedron: Asymmetry. 1804 - 1808. 15. 18. 2007. http://dx.doi.org/10.1016/j.tetasy.2007.07.004 . 10.1016/j.tetasy.2007.07.004 . Tetrahedron: Asymmetry

A Comparison of (R,R)-Me-DUPHOS and (R,R)-DUPHOS-iPr Ligands in the Pd0-Catalysed Asymmetric Allylic Alkylation Reaction: Stereochemical and Kinetic Considerations

Prates Ramalho, João Paulo; Burke, Anthony; Carreiro, Elisabete P.; Moura, Nuno M. M., 2007. https://www.sciencedirect.com/science/article/abs/pii/S0022328X07004871 .

Development of a new stereoselective approach to tertiary¿¿alpha-hydroxy esters

BURKE, Anthony, 2006. https://www.sciencedirect.com/science/article/pii/S0040403906012895?via%3Dihub .

Catalytic epoxidation of olefins using MoO3 and TBHP: Effect of the addition of chiral 2-substituted pyridines on the catalytic rate and asymmetric induction

da Palma Carreiro, Elisabete; Monteiro, Carlos; Guo, Yong-en; Burke, Anthony J.; Rodrigues, Ana Isabel, Journal of Molecular Catalysis A: Chemical. 295 - 298. 1-2. 260. 2006. http://dx.doi.org/10.1016/j.molcata.2006.07.047 . 10.1016/j.molcata.2006.07.047 . Journal of Molecular Catalysis A: Chemical

Arylid-Box: A new family of chiral bis-oxazoline ligands for metal mediated catalytic enantioselective synthesis

Carreiro, Elisabete da Palma; Chercheja, Serghei; Moura, Nuno M.M.; Gertrudes, Cláudia S.C.; Burke, Anthony J., Inorganic Chemistry Communications. 823 - 826. 8. 9. 2006. http://dx.doi.org/10.1016/j.inoche.2006.04.031 . 10.1016/j.inoche.2006.04.031 . Inorganic Chemistry Communications

Catalytic epoxidation of olefins using MoO3 and TBHP: Mechanistic considerations and the effect of amine additives on the reaction

da Palma Carreiro, Elisabete; Burke, Anthony J., Journal of Molecular Catalysis A: Chemical. 123 - 128. 1-2. 249. 2006. http://dx.doi.org/10.1016/j.molcata.2005.12.043 . 10.1016/j.molcata.2005.12.043 . Journal of Molecular Catalysis A: Chemical

Synthesis, characterisation and reactivity of oxodiperoxo-[2-(1-pyrazolyl)-6-menthylpyridine]molybdenum(VI): The first chiral 2-(1-pyrazole)pyridineoxodiperoxomolybdenum(VI) complex

Carreiro, Elisabete da Palma; Yong-En, Guo; Burke, Anthony J., Inorganica Chimica Acta. 1519 - 1523. 5. 359. 2006. http://dx.doi.org/10.1016/j.ica.2005.11.021 . 10.1016/j.ica.2005.11.021 . Inorganica Chimica Acta

Stereoselective alkylation of tartrate derivatives. A concise route to (+)-O-methylpiscidic acid and natural analogues

Burke, Anthony J.; Maycock, Christopher D.; Ventura, M. Rita, Organic & Biomolecular Chemistry. 12. 4. 2006. http://dx.doi.org/10.1039/b606362b . 10.1039/b606362b . Organic & Biomolecular Chemistry

Highly Stereoselective Aldol Reaction for the Synthesis of ?-Lactones Starting from Tartaric Acid.

Barros, M. Teresa; Burke, Anthony J.; Lou, Ji-Dong; Maycock, Christopher D.; Wahnon, Jorge R., ChemInform. 12. 36. 2005. http://dx.doi.org/10.1002/chin.200512238 . 10.1002/chin.200512238 . ChemInform

Approaches towards catalytic asymmetric epoxidations with methyltrioxorhenium(VII) (MTO): Synthesis and evaluation of chiral non-racemic 2-substituted pyridines

Carreiro, Elisabete da Palma; Yong-En, Guo; Burke, Anthony J., Journal of Molecular Catalysis A: Chemical. 285 - 292. 1-2. 235. 2005. http://dx.doi.org/10.1016/j.molcata.2005.03.022 . 10.1016/j.molcata.2005.03.022 . Journal of Molecular Catalysis A: Chemical

Isbut-Box: A new chiral C2 symmetric bis-oxazoline for catalytic enantioselective synthesis

da Plama Carreiro, Elisabete; Chercheja, Serghei; Burke, Anthony J.; Ramalho, J.P. Prates; Rodrigues, Ana Isabel, Journal of Molecular Catalysis A: Chemical. 38 - 45. 1-2. 236. 2005. http://dx.doi.org/10.1016/j.molcata.2005.04.011 . 10.1016/j.molcata.2005.04.011 . Journal of Molecular Catalysis A: Chemical

Asymmetric synthesis and applications of ß-amino Weinreb amides: asymmetric synthesis of (S)-coniine

Burke, Anthony J.; Davies, Stephen G.; Garner, A. Christopher; McCarthy, Tom D.; Roberts, Paul M.; Smith, Andrew D.; Rodriguez-Solla, Humberto; Vickers, Richard J., Org. Biomol. Chem.. 1387 - 1394. 9. 2. 2004. http://dx.doi.org/10.1039/b402531h . 10.1039/b402531h . Org. Biomol. Chem.

An efficient and selective method for the epoxidation of olefins using urea-hydrogen peroxide and methyltrioxorhenium (VII) (MTO) catalyst with heterocyclic aromatic amines

da Palma Carreiro, Elisabete; Burke, Anthony J; Curto, Maria João Marcelo; Teixeira, Adriano J.R, Journal of Molecular Catalysis A: Chemical. 69 - 72. 1-2. 217. 2004. http://dx.doi.org/10.1016/j.molcata.2004.03.036 . 10.1016/j.molcata.2004.03.036 . Journal of Molecular Catalysis A: Chemical

Asymmetric Synthesis of anti-(2S,3S)- and syn-(2R,3S)-Diaminobutanoic acid.

BURKE, Anthony, 2003. https://pubs.rsc.org/en/content/articlelanding/2003/ob/b306936m/unauth#!divAbstract .

Thermostabilization of Proteins by Diglycerol Phosphate, a New Compatible Solute from the HyperthermophileArchaeoglobus fulgidus

Lamosa, Pedro; Burke, Anthony; Peist, Ralf; Huber, Robert; Liu, Ming-Y.; Silva, Gabriela; Rodrigues-Pousada, Claudina; et al, Applied and Environmental Microbiology. 1974 - 1979. 5. 66. 2000. http://dx.doi.org/10.1128/aem.66.5.1974-1979.2000 . 10.1128/aem.66.5.1974-1979.2000 . Applied and Environmental Microbiology

(E)-6-Methoxy-3-(a-methoxybenzylidene)benzo[b]furan-2(3H)-one at 173 K

Burke, Anthony J.; Schmalle, Helmut W.; Brady, Bernard A.; O'Sullivan, W. Ivo, Acta Crystallographica Section C Crystal Structure Communications. 484 - 486. 4. 56. 2000. http://dx.doi.org/10.1107/s0108270100000731 . 10.1107/s0108270100000731 . Acta Crystallographica Section C Crystal Structure Communications

The alkylation of a novel acetal derived from (2R,3R)-(+)-tartaric acid: An unexpected rearrangement

Barros, M.Teresa; Burke, Anthony J.; Maycock, Christopher D., Tetrahedron Letters. 1583 - 1586. 8. 40. 1999. http://dx.doi.org/10.1016/s0040-4039(98)02650-1 . 10.1016/s0040-4039(98)02650-1 . Tetrahedron Letters

Flavonoid epoxides. Part 22. Establishment of the configuration of the diastereomeric solvolysis products of 2-arylmethylenebenzo[b]furan-3(2H)-one (aurone) epoxides

Burke, Anthony J.; Ivo O'Sullivan, W., Tetrahedron. 2169 - 2180. 10. 54. 1998. http://dx.doi.org/10.1016/s0040-4020(97)10429-x . 10.1016/s0040-4020(97)10429-x . Tetrahedron

Flavonoid epoxides. Part 20. Some unusual reactions of dimethyldioxirane (DMD) with flavonoid compounds

Burke, Anthony J.; Ivo O'Sullivan, W., Tetrahedron. 8491 - 8500. 25. 53. 1997. http://dx.doi.org/10.1016/s0040-4020(97)00506-1 . 10.1016/s0040-4020(97)00506-1 . Tetrahedron

Aspects of the Algar-Flynn-Oyamada (AFO) reaction

Bennett, Michael; Burke, Anthony J.; Ivo O'Sullivan, W., Tetrahedron. 7163 - 7178. 20. 52. 1996. http://dx.doi.org/10.1016/0040-4020(96)00334-1 . 10.1016/0040-4020(96)00334-1 . published Tetrahedron

Asymmetric synthesis of (2S,3R)-3-amino-2-hydroxydecanoic acid: The unknown amino acid component of microginin

Bannage, Mark E.; Burke, Anthony J.; Davies, Stephen G.; Goodwin, Christopher J., Tetrahedron: Asymmetry. 203 - 206. 2. 5. 1994. http://dx.doi.org/10.1016/s0957-4166(00)86173-x . 10.1016/s0957-4166(00)86173-x . Tetrahedron: Asymmetry

All projects

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2023/03/01 - 2026/02/28

ConChiMOL New Structurally Contorted and Chiral Molecules for Optoeletronic Applications

2022.01391.PTDC

Principal investigator

2019/10 -

Nautilus: Materiais e Tecnologias Avançadas de Produção

SAMA SmartU-City

Funders: Agencia Nacional de Investigacion e Innovacion

2019/02 -

De Polímeros Molecularmente Impressos a sensores ópticos baseados em MIPs: uma ferramenta "light-up" para a análise de pesticidas em azeite

PTDC/ASP-AGR/30097/2017

Funders: Fundação para a Ciência e a Tecnologia

2018/10 - 2021/09

Desenvolvimento de Novos Nanopartículas de Prata no Hidrogel como Medicamentos Veterinários

ALT20-03-247-FEDER-033578

Funders: Alentejo2020

2016/06 - 2019/06

Novos Processos Catalíticos e Catalisadores para a obtenção de Fármacos

ALT20-03-0145-FEDER-021889

Funders: Agência Nacional de Inovação SA

2015/09 - 2017/08

Using Enantioselective reductions with organocatalysts as a means to obtaining key drugs for neurodegenerative diseases

Ref. 441.00

Funders: Fundação para a Ciência e a Tecnologia

2015/12 - 2019/01

Novos Processos Catalíticos e Catalisadores para a obtenção de Fármacos

ALT20-03-0145-FEDER-017054

Funders: Agência Nacional de Inovação SA

2015/01 - 2019/10

Portuguese Olive Oil Omics for traceability and authenticity

PTDC/AGR-PRO/2003/2014

Funders: Fundação para a Ciência e a Tecnologia

2012/11 - 2015/06

INMOLFARM - Molecular Innovation and Drug Discovery) (Inovação Molecular e Descoberta de Farmacos - Novas Estratégias para a Descoberta de Novos Fármacos), 2012, ALENT-57-2011-20. (Coordinator), 691k€. (Discovery of new drugs for neurodegenerative disease

ALENT-57-2011-20

Funders: INAlentejo

2012/05 - 2015/04

Molecularly Imprinted Polymers solid-phase extraction: A new highly selective and promising approach for trace analysis of pesticide residues in olive oil

117544

Funders: Universidade de Coimbra

2012/11 - 2014/12

Materials and Production Technology Laboratory (LADECA)

ALENT-07-0262-FEDER-001878

Funders: Governo da República Portuguesa Ministério da Ciência Tecnologia e Ensino Superior

2007/01 - 2009/12

Synthesis of Novel Chiral Phosphorous and Nitrogen based ligands for Homogeneous and Heterogeneous Catalytic Asymmetric Synthesis

Provided by PTCRIS: 82721

Funders: Universidade de Coimbra

2005/01 - 2009/01

Synthesis of New Chiral Ligands containing Phosphorous and Nitrogen for Homogenous and Heterogenous Asymmetric Catalytic Synthesis

PPCDT/QUI/55779/2004

Funders: Fundação para a Ciência e a Tecnologia

2005/09 - 2007/06

Synthesis of Novel Chiral Phosphorous and Nitrogen based ligands for Homogeneous and Heterogeneous Catalytic Asymmetric Synthesis

Provided by PTCRIS: 55779

Funders: Universidade de Coimbra

2004/09 - 2006/08

New Chiral Diphosphine with C2 Symmetry for catalytic Asymmetric Reactions with Pd: Strategies for recycling the Catalyst

E-117/04

Funders: Fundação para a Ciência e a Tecnologia

2002/12 - 2006/05

Development of New Solid Supported Catalysts for the Asymmetric Synthesis of Biologically Active Compounds

POCTI/QUI/38797/2001

Funders: Fundação para a Ciência e a Tecnologia

2000/01 - 2003/01

Selective, Efficient and Clean Synthesis of Biologically Active Compounds

POCTI/QUI/35358/2000

Funders: Fundação para a Ciência e a Tecnologia

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