Rui Nobre

Simple and Fast SEC-Based Protocol to Isolate Human Plasma-Derived Extracellular Vesicles for Transcriptional Research

Gaspar, Laetitia S.; Santana, Magda M.; Henriques, Carina; Pinto, Maria M.; Ribeiro-Rodrigues, Teresa M.; Girão, Henrique; Nobre, Rui Jorge; Pereira de Almeida, Luís, Molecular Therapy - Methods & Clinical Development. 723 - 737. 18. 2020. http://dx.doi.org/10.1016/j.omtm.2020.07.012 . 10.1016/j.omtm.2020.07.012 . Molecular Therapy - Methods & Clinical Development

Protocol for the Characterization of the CAG Tract and Flanking Polymorphisms in Machado-Joseph Disease: Impact on Diagnosis and Development of Gene-Based Therapies

Lopes, Sara Monteiro; Faro, Rosário; Lopes, Miguel Monteiro; Onofre, Isabel; Mendonça, Nuno; Ribeiro, Joana; Januário, Cristina; Nobre, Rui Jorge; Pereira de Almeida, Luís, The Journal of Molecular Diagnostics. 2020. http://dx.doi.org/10.1016/j.jmoldx.2020.03.003 . 10.1016/j.jmoldx.2020.03.003 . published The Journal of Molecular Diagnostics

Trehalose alleviates the phenotype of Machado–Joseph disease mouse models

Santana, Magda M.; Paixão, Susana; Cunha-Santos, Janete; Silva, Teresa Pereira; Trevino-Garcia, Allyson; Gaspar, Laetitia S.; Nóbrega, Clévio; et al, Journal of Translational Medicine. 1. 18. 2020. http://dx.doi.org/10.1186/s12967-020-02302-2 . 10.1186/s12967-020-02302-2 . Journal of Translational Medicine

Repeated Mesenchymal Stromal Cell Treatment Sustainably Alleviates Machado-Joseph Disease

Oliveira Miranda, Catarina; Marcelo, Adriana; Silva, Teresa Pereira; Barata, João; Vasconcelos-Ferreira, Ana; Pereira, Dina; Nóbrega, Clévio; et al, Molecular Therapy. 2131 - 2151. 9. 26. 2018. http://dx.doi.org/10.1016/j.ymthe.2018.07.007 . 10.1016/j.ymthe.2018.07.007 . published Molecular Therapy

Hypoxia mimetic induces lipid accumulation through mitochondrial dysfunction and stimulates autophagy in murine preadipocyte cell line

Marques, Ana Patrícia; Rosmaninho-Salgado, Joana; Estrada, Marta; Cortez, Vera; Nobre, Rui Jorge; Cavadas, Cláudia, Biochimica et Biophysica Acta (BBA) - General Subjects. 673 - 682. 3. 1861. 2017. http://dx.doi.org/10.1016/j.bbagen.2016.12.005 . 10.1016/j.bbagen.2016.12.005 . published Biochimica et Biophysica Acta (BBA) - General Subjects

Fibroblasts of Machado Joseph Disease patients reveal autophagy impairment

Onofre, Isabel; Mendonça, Nuno; Lopes, Sara; Nobre, Rui; de Melo, Joana Barbosa; Carreira, Isabel Marques; Januário, Cristina; Gonçalves, António Freire; de Almeida, Luis Pereira, Scientific Reports. 1. 6. 2016. http://dx.doi.org/10.1038/srep28220 . 10.1038/srep28220 . published Scientific Reports

Gephyrin Cleavage in In Vitro Brain Ischemia Decreases GABAA Receptor Clustering and Contributes to Neuronal Death

Costa, João T.; Mele, Miranda; Baptista, Márcio S.; Gomes, João R.; Ruscher, Karsten; Nobre, Rui J.; de Almeida, Luís Pereira; Wieloch, Tadeusz; Duarte, Carlos B., Molecular Neurobiology. 3513 - 3527. 6. 53. 2015. http://dx.doi.org/10.1007/s12035-015-9283-2 . 10.1007/s12035-015-9283-2 . published Molecular Neurobiology

Stimulation of Neural Stem Cell Proliferation by Inhibition of Phosphodiesterase 5

Santos, Ana I.; Carreira, Bruno P.; Nobre, Rui J.; Carvalho, Caetana M.; Araújo, Inês M., Stem Cells International. 1 - 13. 2014. 2014. http://dx.doi.org/10.1155/2014/878397 . 10.1155/2014/878397 . published Stem Cells International

Calpain inhibition reduces ataxin-3 cleavage alleviating neuropathology and motor impairments in mouse models of Machado–Joseph disease

Simões, Ana Teresa; Gonçalves, Nélio; Nobre, Rui Jorge; Duarte, Carlos Bandeira; Pereira de Almeida, Luís, Human Molecular Genetics. 4932 - 4944. 18. 23. 2014. http://dx.doi.org/10.1093/hmg/ddu209 . 10.1093/hmg/ddu209 . published Human Molecular Genetics

Gene Therapy for Parkinsons and Alzheimers Diseases: from the Bench to Clinical Trials

Jorge Nobre, Rui; Pereira de Almeida, Luis, Current Pharmaceutical Design. 3434 - 3445. 31. 17. 2011. http://dx.doi.org/10.2174/138161211798072472 . 10.2174/138161211798072472 . published Current Pharmaceutical Design

Characterization of common and rare human papillomaviruses in Portuguese women by the polymerase chain reaction, restriction fragment length polymorphism and sequencing

Nobre, Rui Jorge; Cruz, Eugénia; Real, Odete; de Almeida, Luís Pereira; Martins, Teresa C., Journal of Medical Virology. 1024 - 1032. 6. 82. 2010. http://dx.doi.org/10.1002/jmv.21756 . 10.1002/jmv.21756 . published Journal of Medical Virology

E7 Oncoprotein of Novel Human Papillomavirus Type 108 Lacking the E6 Gene Induces Dysplasia in Organotypic Keratinocyte Cultures

Nobre, R. J.; Herraez-Hernandez, E.; Fei, J.-W.; Langbein, L.; Kaden, S.; Grone, H.-J.; de Villiers, E.-M., Journal of Virology. 2907 - 2916. 7. 83. 2009. http://dx.doi.org/10.1128/jvi.02490-08 . 10.1128/jvi.02490-08 . published Journal of Virology

Complete genotyping of mucosal human papillomavirus using a restriction fragment length polymorphism analysis and an original typing algorithm

Nobre, Rui Jorge; de Almeida, Luís Pereira; Martins, Teresa C., Journal of Clinical Virology. 13 - 21. 1. 42. 2008. http://dx.doi.org/10.1016/j.jcv.2007.11.021 . 10.1016/j.jcv.2007.11.021 . published Journal of Clinical Virology