Overview

Paulo J. Oliveira is currently Principal Investigator at the CNC – Center for Neuroscience and Cell Biology, University of Coimbra, Portugal. He is the current leader of the “Mitochondria, Metabolism and Disease” group and of the MitoXT: Mitochondrial Toxicology and Experimental Therapeutics laboratory. He received his Bachelor of Science in Biochemistry from the University de Coimbra in 1999. In 2003, he completed his PhD in Cellular Biology from the same University. After completing his doctorate, Paulo Oliveira spent more than three years working at the Medical School of the University of Minnesota, Duluth, USA, where he collaborated with several researchers and contributed to the publication of several peer-reviewed manuscripts. Paulo Oliveira current research interests focus on mitochondrial biology, investigating the alteration of cardiac mitochondrial function by physical activity and diet, cardiac mitochondrial dysfunction and cell death caused by anti-neoplastic agents, mitochondrial alterations during cancer stem cell differentiation and carcinogenesis or rational designing of mitochondria-directed antioxidants. Paulo has about 230 peer-reviewed publications and a large number of collaborations in Europe, Africa and in the USA. He has also received several prizes from the Portuguese Cardiology Society for his work on cardiac mitochondrial research. Besides research, Paulo Oliveira is often involved in teaching at the Department of Life Sciences, University of Coimbra, as well as in other Universities in Portugal and elsewhere, besides in numerous science communication activities. Of importance, he has maintained a consistent primary role in the organization of national and international scientific meetings, including the International Courses in Toxicology (2005-2010 in Coimbra), Annual Meeting of the European Society for Clinical Investigation (2013, Albufeira, Portugal and 2019, Coimbra, Portugal), the 2014 Meeting of the Portuguese Biochemical Society, and FEBS Advanced Lecture Courses in Oncometabolism (2017, Figueira da Foz, Portugal and 2019 Luso, Portugal). Since May 2019, Paulo Oliveira is also President of the European Society for Clinical Investigation, after being its Vice-President for 2 years. Paulo Oliveira has also been reviewer for more than 40 different scientific journals and over 10 different funding agencies, including the European Commission (Research Executive Agency) and the Portuguese Foundation for Science and Technology. His research group is supported by competitive national and international funding agencies, including the Portuguese Foundation for Science and Technology, the European Commission, and private foundations. Paulo is also co-founder of the start-up MitoTAG and is co-inventor in two patents. Since 2020, Paulo is Vice-President of the CNC – Center for Neuroscience and Cell Biology, University of Coimbra, Portugal.

Affiliation

CNC - Center for Neuroscience and Cell Biology, University of Coimbra

Publications

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Information about journal articles, updated at 17-12-2023, from platform CIÊNCIAVITAE.

Redox profiles of amyotrophic lateral sclerosis lymphoblasts with or without known SOD1 mutations

Teresa Cunha-Oliveira; Daniela Franco Silva; Luis Segura; Inês Baldeiras; Ricardo Marques; Tatiana Rosenstock; Paulo J. Oliveira; Filomena S. G. Silva, European Journal of Clinical Investigation. 2022. https://doi.org/10.1111/eci.13798 . 10.1111/eci.13798 . European Journal of Clinical Investigation

Modulation of cellular redox environment as a novel therapeutic strategy for Parkinson's disease

Cláudia M. Deus; José Teixeira; Nuno Raimundo; Paolo Tucci; Fernanda Borges; Luciano Saso; Paulo J. Oliveira, European Journal of Clinical Investigation. 2022. https://doi.org/10.1111/eci.13820 . 10.1111/eci.13820 . European Journal of Clinical Investigation

Mitochondrial and metabolic remodelling in human skin fibroblasts in response to glucose availability

Sónia A. Pinho; Cláudio F. Costa; Cláudia M. Deus; Sonia L. C. Pinho; Inês Miranda-Santos; Gonçalo Afonso; Olivia Bagshaw; et al, The FEBS Journal. 2022. https://doi.org/10.1111/febs.16413 . 10.1111/febs.16413 . The FEBS Journal

Evaluation of 6-Hydroxydopamine and Rotenone In Vitro Neurotoxicity on Differentiated SH-SY5Y Cells Using Applied Computational Statistics

Rui F. Simões; Paulo J. Oliveira; Teresa Cunha-Oliveira; Francisco B. Pereira, International Journal of Molecular Sciences. 3009 - 3009. 6. 23. 2022. https://doi.org/10.3390/ijms23063009 . 10.3390/ijms23063009 . International Journal of Molecular Sciences

Effect of a Novel Hydroxybenzoic Acid Based Mitochondria Directed Antioxidant Molecule on Bovine Sperm Function and Embryo Production

João Campos Santos; Carla Cruz Marques; Maria Conceição Baptista; Jorge Pimenta; José Carlos Santos Teixeira; Liliana Montezinho; Fernando Cagide; et al, Animals. 2022. https://www.mdpi.com/2076-2615/12/7/804 . 10.3390/ani12070804 . Animals

The heart of FOIE GRAS and mtFOIE GRAS: fundamental and clinical investigation for training and innovation in non-alcoholic fatty liver disease

Paulo J Oliveira, European Heart Journal. 2022. https://doi.org/10.1093/eurheartj/ehab399 . 10.1093/eurheartj/ehab399 . European Heart Journal

Bioenergetic remodeling in the pathophysiology and treatment of nonalcoholic fatty liver disease

Anabela Marisa Azul; Martin Winter; Daniel Silva; Liljana Georgievska; Paulo J. Oliveira, European Journal of Clinical Investigation. 2022. https://doi.org/10.1111/eci.13749 . 10.1111/eci.13749 . European Journal of Clinical Investigation

The Role of Glucosinolates from Cruciferous Vegetables (Brassicaceae) in Gastrointestinal Cancers: From Prevention to Therapeutics

Catarina Melim; Maria R. Lauro; Isabel M. Pires; Paulo J. Oliveira; Célia Cabral, Pharmaceutics. 2022. https://doi.org/10.3390/pharmaceutics14010190 . 10.3390/pharmaceutics14010190 . Pharmaceutics

H9c2(2-1)-based sulforhodamine B assay as a possible alternative in vitro platform to investigate effluent and metals toxicity on fish

Elsa T. Rodrigues; Miguel A. Pardal; Eduarda Pereira; Joana F. Monteiro; Ana C. Certal; Paulo J. Oliveira, Chemosphere. 2021. https://doi.org/10.1016/j.chemosphere.2021.130009 . 10.1016/j.chemosphere.2021.130009 . Chemosphere

Glutaminolysis is a metabolic route essential for survival and growth of prostate cancer cells and a target of 5a-dihydrotestosterone regulation

Henrique J. Cardoso; Marília I. Figueira; Cátia V. Vaz; Tiago M. A. Carvalho; Luís A. Brás; Patrícia A. Madureira; Paulo J. Oliveira; Vilma A. Sardão; Sílvia Socorro, Cellular Oncology. 2021. https://doi.org/10.1007/s13402-020-00575-9 . 10.1007/s13402-020-00575-9 . Cellular Oncology

Fine-Tuning the Biological Profile of Multitarget Mitochondriotropic Antioxidants for Neurodegenerative Diseases

Daniel Chavarria; Ophelie DA SILVA; Sofia Benfeito; Sandra Barreiro; Jorge Garrido; Cagide-Fagín; Pedro Soares; et al, Antioxidants. 2021. https://www.mdpi.com/2076-3921/10/2/329 . 10.3390/antiox10020329 . Antioxidants

Quantitative analysis of neuronal mitochondrial movement reveals patterns resulting from neurotoxicity of rotenone and 6-hydroxydopamine

Rui F. Simões; Rute Pino; Maurício Moreira-Soares; Jaromira Kovarova; Jiri Neuzil; Rui Travasso; Paulo J. Oliveira; Teresa Cunha-Oliveira; Francisco B. Pereira, The FASEB Journal. 12. 35. 2021. https://doi.org/10.1096/fj.202100899R . 10.1096/fj.202100899R . The FASEB Journal

Cytotoxicity and Mitochondrial Effects of Phenolic and Quinone-Based Mitochondria-Targeted and Untargeted Antioxidants on Human Neuronal and Hepatic Cell Lines: A Comparative Analysis

Carlos Fernandes; Afonso J. C. Videira; Caroline D. Veloso; Sofia Benfeito; Pedro Soares; João D. Martins; Beatriz Gonçalves; et al, Biomolecules. 1605 - 1605. 11. 11. 2021. https://doi.org/10.3390/biom11111605 . 10.3390/biom11111605 . Biomolecules

Metabolic Disease Programming: From Mitochondria to Epigenetics, Glucocorticoid Signalling and Beyond

Luís F. Grilo; Carolina Tocantins; Mariana S. Diniz; Rodrigo Mello Gomes; Paulo J. Oliveira; Paulo Matafome; Susana P. Pereira, European Journal of Clinical Investigation. 2021. https://doi.org/10.1111/eci.13625 . 10.1111/eci.13625 . European Journal of Clinical Investigation

A mitochondria-targeted caffeic acid derivative reverts cellular and mitochondrial defects in human skin fibroblasts from male sporadic Parkinson's disease patients

Cláudia M. Deus; Susana P. Pereira; Teresa Cunha-Oliveira; José Teixeira; Rui F. Simões; Fernando Cagide; Sofia Benfeito; et al, Redox Biology. 102037 - 102037. 45. 2021. https://doi.org/10.1016/j.redox.2021.102037 . 10.1016/j.redox.2021.102037 . Redox Biology

Afrostyrax lepidophyllus Mildbr. and Monodora myristica (Gaertn.) Dunal Extracts Decrease Doxorubicin Cytotoxicity on H9c2 Cardiomyoblasts

Bruno M. Moukette; José P. Castelão-Baptista; Luciana Ferreira; Ana M. Silva; Rui F. Simões; Célia Cabral; Constant A. Pieme; et al, Evidence-Based Complementary and Alternative Medicine. 2021. https://doi.org/10.1155/2021/8858165 . 10.1155/2021/8858165 . Evidence-Based Complementary and Alternative Medicine

Refinement of a differentiation protocol using neuroblastoma SH-SY5Y cells for use in neurotoxicology research

Rui F. Simões; Rafaela Ferrão; Margarida R. Silva; Sonia L.C. Pinho; Lino Ferreira; Paulo J. Oliveira; Teresa Cunha-Oliveira, Food and Chemical Toxicology. 111967 - 111967. 149. 2021. https://doi.org/10.1016/j.fct.2021.111967 . 10.1016/j.fct.2021.111967 . Food and Chemical Toxicology

Doxorubicin persistently rewires cardiac circadian homeostasis in mice

Luciana L. Ferreira; Marlene Cervantes; Hugo J. C. Froufe; Conceição Egas; Teresa Cunha-Oliveira; Paolo Sassone-Corsi; Paulo J. Oliveira, Archives of Toxicology. 257 - 271. 1. 94. 2020. https://doi.org/10.1007/s00204-019-02626-z . 10.1007/s00204-019-02626-z . Archives of Toxicology

Mitochondrial Determinants of Doxorubicin-Induced Cardiomyopathy

Kendall B. Wallace; Vilma A. Sardão; Paulo J. Oliveira, Circulation Research. 926 - 941. 7. 126. 2020. https://doi.org/10.1161/CIRCRESAHA.119.314681 . 10.1161/CIRCRESAHA.119.314681 . Circulation Research

Urine-Derived Stem Cells: Applications in Regenerative and Predictive Medicine

Guida Bento; Aygul K. Shafigullina; Albert A. Rizvanov; Vilma A. Sardão; Maria Paula Macedo; Paulo J. Oliveira, Cells. 573 - 573. 3. 9. 2020. https://doi.org/10.3390/cells9030573 . 10.3390/cells9030573 . Cells

Drp1-mediated mitochondrial fission regulates calcium and F-actin dynamics during wound healing

Susana Ponte; Lara Carvalho; Maria Gagliardi; Isabel Campos; Paulo J. Oliveira; António Jacinto, Biology Open. 2020. https://doi.org/10.1242/bio.048629 . 10.1242/bio.048629 . Biology Open

Western Diet Causes Obesity-Induced Nonalcoholic Fatty Liver Disease Development by Differentially Compromising the Autophagic Response

Ines C. M. Simoes; Agnieszka Karkucinska-Wieckowska; Justyna Janikiewicz; Sylwia Szymanska; Maciej Pronicki; Pawel Dobrzyn; Michal Dabrowski; et al, Antioxidants. 995 - 995. 10. 9. 2020. https://doi.org/10.3390/antiox9100995 . 10.3390/antiox9100995 . Antioxidants

Dihydroorotate dehydrogenase inhibitors in SARS-CoV-2 infection

Ana R. Coelho; Paulo J. Oliveira, European Journal of Clinical Investigation. 2020. https://doi.org/10.1111/eci.13366 . 10.1111/eci.13366 . European Journal of Clinical Investigation

Publicly stressing the role of mitochondria in NAFLD with(in) a sports event

Mireia Alemany-Pagès; Rui Tavares; Sara Varela Amaral; Ana Teresa Barros-Viegas; Paulo J. Oliveira; João Ramalho-Santos; Anabela Marisa Azul, European Journal of Clinical Investigation. 2020. https://doi.org/10.1111/eci.13234 . 10.1111/eci.13234 . European Journal of Clinical Investigation

Oxidative Stress in Amyotrophic Lateral Sclerosis: Pathophysiology and Opportunities for Pharmacological Intervention

Teresa Cunha-Oliveira; Liliana Montezinho; Catarina Mendes; Omidreza Firuzi; Luciano Saso; Paulo J. Oliveira; Filomena S. G. Silva; Jos L. Quiles, Oxidative Medicine and Cellular Longevity. 2020. https://doi.org/10.1155/2020/5021694 . 10.1155/2020/5021694 . Oxidative Medicine and Cellular Longevity

Targeting mitochondria to oppose the progression of nonalcoholic fatty liver disease

Ignazio Grattagliano; Liliana P. Montezinho; Paulo J. Oliveira; Gema Frühbeck; Javier Gómez-Ambrosi; Fabrizio Montecucco; Federico Carbone; et al, Biochemical Pharmacology. 34 - 45. 160. 2019. https://doi.org/10.1016/j.bcp.2018.11.020 . 10.1016/j.bcp.2018.11.020 . Biochemical Pharmacology

Antioxidant Versus Pro-Apoptotic Effects of Mushroom-Enriched Diets on Mitochondria in Liver Disease

Adriana Fontes; Mireia Alemany-Pagès; Paulo J. Oliveira; João Ramalho-Santos; Hans Zischka; Anabela Marisa Azul, International Journal of Molecular Sciences. 3987 - 3987. 16. 20. 2019. https://doi.org/10.3390/ijms20163987 . 10.3390/ijms20163987 . International Journal of Molecular Sciences

Single nanomolar doxorubicin exposure triggers compensatory mitochondrial responses in H9c2 cardiomyoblasts

Luciana L. Ferreira; Teresa Cunha-Oliveira; Caroline D. Veloso; Cláudio F. Costa; Kendall B. Wallace; Paulo J. Oliveira, Food and Chemical Toxicology. 450 - 461. 124. 2019. https://doi.org/10.1016/j.fct.2018.12.017 . 10.1016/j.fct.2018.12.017 . Food and Chemical Toxicology

A Mitochondrial Approach to Cardiovascular Risk and Disease

Caroline D. Veloso; Getachew D. Belew; Luciana L. Ferreira; Luís Filipe Fragoso Grilo; John G. Jones; Piero Portincasa; Vilma A. Sardão; Paulo J. Oliveira, Current Protein & Peptide Science. 2019. https://doi.org/10.2174/1389203720666190830163735 . 10.2174/1389203720666190830163735 . Current Protein & Peptide Science

Cell-based assays seem not to accurately predict fish short-term toxicity of pesticides

Elsa T. Rodrigues; Ana T. Varela; Miguel A. Pardal; Paulo J. Oliveira, Environmental Pollution. 476 - 482. 252. 2019. https://doi.org/10.1016/j.envpol.2019.05.033 . 10.1016/j.envpol.2019.05.033 . Environmental Pollution

Bioisosteric OH- to SH-replacement changes the antioxidant profile of ferulic acid

Daniel Chavarria; Carlos Fernandes; Tiago Silva; Jorge Garrido; Fernando Remião; Paulo J. Oliveira; Fernanda Borges, Organic & Biomolecular Chemistry. 2019. https://doi.org/10.1039/C9OB01875A . 10.1039/C9OB01875A . Organic & Biomolecular Chemistry

Insights into the Discovery of Novel Neuroprotective Agents: A Comparative Study between Sulfanylcinnamic Acid Derivatives and Related Phenolic Analogues

Daniel Chavarria; Carlos Fernandes; Brandon Aguiar; Tiago Silva; Jorge Garrido; Fernando Remiao; Paulo J. Oliveira; Eugenio Uriarte; Borges Fernanda, Molecules. 2019. https://www.mdpi.com/1420-3049/24/23/4405 . 10.3390/molecules24234405 . Molecules

Development of a PEGylated-Based Platform for Efficient Delivery of Dietary Antioxidants Across the Blood-Brain Barrier.

Fernandes C; Pinto M; Martins C; Gomes MJ; Sarmento B; Oliveira PJ; Remião F; Borges F, Bioconjugate chemistry. 2018. http://europepmc.org/abstract/med/29635917 . 10.1021/acs.bioconjchem.8b00151 . Bioconjugate chemistry

Evaluation of Respiration with Clark-Type Electrode in Isolated Mitochondria and Permeabilized Animal Cells.

Silva AM; Oliveira PJ, Methods in molecular biology (Clifton, N.J.). 2018. http://europepmc.org/abstract/med/29850992 . 10.1007/978-1-4939-7831-1_2 . Methods in molecular biology (Clifton, N.J.)

Discovery of a new mitochondria permeability transition pore (mPTP) inhibitor based on gallic acid

José Teixeira; Catarina Oliveira; Fernando Cagide; Ricardo Amorim; Jorge Garrido; Fernanda Borges; Paulo J. Oliveira, Journal of Enzyme Inhibition and Medicinal Chemistry. 567 - 576. 1. 33. 2018. https://doi.org/10.1080/14756366.2018.1442831 . 10.1080/14756366.2018.1442831 . Journal of Enzyme Inhibition and Medicinal Chemistry

TRAP1 regulates autophagy in lung cancer cells.

Barbosa IA; Vega-Naredo I; Loureiro R; Branco AF; Garcia R; Scott PM; Oliveira PJ, European journal of clinical investigation. 2018. http://europepmc.org/abstract/med/29383696 . 10.1111/eci.12900 . European journal of clinical investigation

Mitochondria: Targeting mitochondrial reactive oxygen species with mitochondriotropic polyphenolic-based antioxidants.

Teixeira J; Deus CM; Borges F; Oliveira PJ, The international journal of biochemistry & cell biology. 2018. http://europepmc.org/abstract/med/29454114 . 10.1016/j.biocel.2018.02.007 . The international journal of biochemistry & cell biology

The beneficial role of exercise in mitigating doxorubicin-induced Mitochondrionopathy.

Marques-Aleixo I; Santos-Alves E; Oliveira PJ; Moreira PI; Magalhães J; Ascensão A, Biochimica et biophysica acta. Reviews on cancer. 2018. http://europepmc.org/abstract/med/29408395 . 10.1016/j.bbcan.2018.01.002 . Biochimica et biophysica acta. Reviews on cancer

SULFATION PATHWAYS: Potential benefits of a sulfated resveratrol derivative for topical application.

Correia-da-Silva M; Rocha V; Marques C; Deus CM; Marques-Carvalho A; Oliveira PJ; Palmeira A; et al, Journal of molecular endocrinology. 2018. http://europepmc.org/abstract/med/29588426 . 10.1530/jme-18-0031 . Journal of molecular endocrinology

Doxorubicin triggers bioenergetic failure and p53 activation in mouse stem cell-derived cardiomyocytes.

Cunha-Oliveira T; Ferreira LL; Coelho AR; Deus CM; Oliveira PJ, Toxicology and applied pharmacology. 2018. http://europepmc.org/abstract/med/29653124 . 10.1016/j.taap.2018.04.009 . Toxicology and applied pharmacology

Mitochondria and Reactive Oxygen Species in Aging and Age-Related Diseases.

Giorgi C; Marchi S; Simoes ICM; Ren Z; Morciano G; Perrone M; Patalas-Krawczyk P; et al, International review of cell and molecular biology. 2018. http://europepmc.org/abstract/med/30072092 . 10.1016/bs.ircmb.2018.05.006 . International review of cell and molecular biology

Hydroxybenzoic Acid Derivatives as Dual-Target Ligands: Mitochondriotropic Antioxidants and Cholinesterase Inhibitors.

Oliveira C; Cagide F; Teixeira J; Amorim R; Sequeira L; Mesiti F; Silva T; et al, Frontiers in chemistry. 2018. http://europepmc.org/abstract/med/29740575 . 10.3389/fchem.2018.00126 . Frontiers in chemistry

Electrochemical Behavior of a Mitochondria-Targeted Antioxidant at an Interface between Two Immiscible Electrolyte Solutions: An Alternative Approach to Study Lipophilicity.

Ribeiro JA; Benfeito S; Cagide F; Teixeira J; Oliveira PJ; Borges F; Silva AF; Pereira CM, Analytical chemistry. 2018. http://europepmc.org/abstract/med/29863846 . 10.1021/acs.analchem.8b00787 . Analytical chemistry

Sources of hepatic glycogen synthesis in mice fed with glucose or fructose as the sole dietary carbohydrate.

Jarak I; Barosa C; Martins FO; Silva JCP; Santos C; Belew GD; Rito J; et al, Magnetic resonance in medicine. 2018. http://europepmc.org/abstract/med/30058123 . 10.1002/mrm.27378 . Magnetic resonance in medicine

Metabolic and Phenotypic Characterization of Human Skin Fibroblasts After Forcing Oxidative Capacity.

Pereira SP; Deus CM; Serafim TL; Cunha-Oliveira T; Oliveira PJ, Toxicological sciences : an official journal of the Society of Toxicology. 2018. http://europepmc.org/abstract/med/29945227 . 10.1093/toxsci/kfy068 . Toxicological sciences : an official journal of the Society of Toxicology

Desrisking the Cytotoxicity of a Mitochondriotropic Antioxidant Based on Caffeic Acid by a PEGylated Strategy

Carlos Fernandes; Sofia Benfeito; Ricardo Amorim; José Teixeira; Paulo J. Oliveira; Fernando Remião; Fernanda Borges, Bioconjugate Chemistry. 2018. https://doi.org/10.1021/acs.bioconjchem.8b00383 . 10.1021/acs.bioconjchem.8b00383 . Bioconjugate Chemistry

Multi-target-directed ligands for Alzheimer's disease: Discovery of chromone-based monoamine oxidase/cholinesterase inhibitors.

Reis J; Cagide F; Valencia ME; Teixeira J; Bagetta D; Pérez C; Uriarte E; et al, European journal of medicinal chemistry. 2018. http://europepmc.org/abstract/med/30245401 . 10.1016/j.ejmech.2018.07.056 . European journal of medicinal chemistry

Reactivation of Dihydroorotate Dehydrogenase-Driven Pyrimidine Biosynthesis Restores Tumor Growth of Respiration-Deficient Cancer Cells.

Bajzikova M; Kovarova J; Coelho AR; Boukalova S; Oh S; Rohlenova K; Svec D; et al, Cell metabolism. 2018. http://europepmc.org/abstract/med/30449682 . 10.1016/j.cmet.2018.10.014 . Cell metabolism

Toxicity of lupane derivatives on anionic membrane models, isolated rat mitochondria and selected human cell lines: Role of terminal alkyl chains

Filipa S. Carvalho; Catarina M. Morais; Jon Holy; Dmytro Krasutsky; Sergiy V. Yemets; Pavel A. Krasutsky; Amália S. Jurado; Paulo J. Oliveira; Teresa L. Serafim, Chemico-Biological Interactions. 198 - 210. 296. 2018. https://doi.org/10.1016/j.cbi.2018.10.002 . 10.1016/j.cbi.2018.10.002 . Chemico-Biological Interactions

Dietary Polyphenols and Mitochondrial Function: Role in Health and Disease

Teixeira, J.; Chavarria, D.; Borges, F.; Wojtczak, L.; Wieckowski, M. R.; Karkucinska-Wieckowska, A.; Oliveira, P. J., Curr Med Chem. 2017. https://www.ncbi.nlm.nih.gov/pubmed/28554320 . 10.2174/0929867324666170529101810 . Curr Med Chem

Protective Effect of Green Tea (Camellia sinensis (L.) Kuntze) against Prostate Cancer: From In Vitro Data to Algerian Patients

Lassed, Somia; Deus, Claudia M.; Djebbari, Radja; Zama, Djamila; Oliveira, Paulo J.; Rizvanov, Albert A.; Dahdouh, Abderrezak; Benayache, Fadila; Benayache, Samir, Evidence-Based Complementary and Alternative Medicine. 91568 - 91568. 2017. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000392530400001&KeyUID=WOS:000392530400001 . 10.1155/2017/1691568 . Evidence-Based Complementary and Alternative Medicine

Sirtuin 1-dependent resveratrol cytotoxicity and pro-differentiation activity on breast cancer cells

Deus, C. M.; Serafim, T. L.; Magalhães-Novais, S.; Vilaça, A.; Moreira, A. C.; Sardão, V. A.; Cardoso, S. M.; Oliveira, P. J., Arch Toxicol. 1261 - 1278. 3. 91. 2017. https://www.ncbi.nlm.nih.gov/pubmed/27358235 . 10.1007/s00204-016-1784-x . Arch Toxicol

Exercise and Doxorubicin Treatment Modulate Cardiac Mitochondrial Quality Control Signaling

Marques-Aleixo, I.; Santos-Alves, E.; Torrella, J. R.; Oliveira, P. J.; Magalhães, J.; Ascensão, A., Cardiovasc Toxicol. 2017. https://www.ncbi.nlm.nih.gov/pubmed/28536949 . 10.1007/s12012-017-9412-4 . Cardiovasc Toxicol

Carvedilol and antioxidant proteins in a type I diabetes animal model

Diogo, Catia V.; Deus, Claudia M.; Lebiedzinska-Arciszewska, Magdalena; Wojtala, Aleksandra; Wieckowski, Mariusz R.; Oliveira, Paulo J., European Journal of Clinical Investigation. 19 - 29. 1. 47. 2017. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000393880700002&KeyUID=WOS:000393880700002 . 10.1111/eci.12696 . European Journal of Clinical Investigation

Horizontal transfer of whole mitochondria restores tumorigenic potential in mitochondrial DNA-deficient cancer cells

Dong, L. F.; Kovarova, J.; Bajzikova, M.; Bezawork-Geleta, A.; Svec, D.; Endaya, B.; Sachaphibulkij, K.; et al, Elife. 6. 2017. https://www.ncbi.nlm.nih.gov/pubmed/28195532 . 10.7554/eLife.22187 . Elife

Evaluation of biological properties of 3,3',4,4'-benzophenonetetracarboxylic dianhydride derivatives and their ability to inhibit hexokinase activity

Kochel, Krzysztof; Tomczyk, Mateusz D.; Simoes, Rui F.; Fraczek, Tomasz; Sobon, Adrian; Oliveira, Paulo J.; Walczak, Krzysztof Z.; et al, Bioorganic & Medicinal Chemistry Letters. 427 - 431. 3. 27. 2017. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000392900600010&KeyUID=WOS:000392900600010 . 10.1016/j.bmc1.2016.12.055 . Bioorganic & Medicinal Chemistry Letters

Flexible nanofilms coated with aligned piezoelectric microfibers preserve the contractility of cardiomyocytes

Gouveia, P. J.; Rosa, S.; Ricotti, L.; Abecasis, B.; Almeida, H. V.; Monteiro, L.; Nunes, J.; et al, Biomaterials. 213 - 228. 139. 2017. https://www.ncbi.nlm.nih.gov/pubmed/28622605 . 10.1016/j.biomaterials.2017.05.048 . Biomaterials

The pathophysiological role of cholecystokinin-1 receptor in mouse cholelithogenesis

Carbone, Federico; Oliveira, Paulo J.; Bonaventura, Aldo; Montecucco, Fabrizio, European Journal of Clinical Investigation. 195 - 196. 2. 47. 2017. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000393880500011&KeyUID=WOS:000393880500011 . 10.1111/eci.12713 . European Journal of Clinical Investigation

Mitochondrial biology in cancer stem cells.

Loureiro R; Mesquita KA; Magalhães-Novais S; Oliveira PJ; Vega-Naredo I, Seminars in cancer biology. 2017. http://europepmc.org/abstract/med/28673608 . 10.1016/j.semcancer.2017.06.012 . Seminars in cancer biology

Development of a Mitochondriotropic Antioxidant Based on Caffeic Acid: Proof of Concept on Cellular and Mitochondrial Oxidative Stress Models

Teixeira, Jose; Cagide, Fernando; Benfeito, Sofia; Soares, Pedro; Garrido, Jorge; Baldeiras, Ines; Ribeiro, Jose A.; et al, Journal of Medicinal Chemistry. 7084 - 7098. 16. 60. 2017. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000408598500017&KeyUID=WOS:000408598500017 . 10.1021/acs.jmedchem.7b00741 . Journal of Medicinal Chemistry

Development of hydroxybenzoic-based platforms as a solution to deliver dietary antioxidants to mitochondria

Teixeira, Jose; Oliveira, Catarina; Amorim, Ricardo; Cagide, Fernando; Garrido, Jorge; Ribeiro, Jose A.; Pereira, Carlos M.; et al, Scientific Reports. 7. 2017. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000406610000093&KeyUID=WOS:000406610000093 . 10.1038/s41598-017-07272-y . Scientific Reports

Berberine-induced cardioprotection and Sirt3 modulation in doxorubicin-treated H9c2 cardiomyoblasts.

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Silva, A.M., Methods in Molecular Biology. 7 - 24. 810. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-82355193801&partnerID=MN8TOARS . 10.1007/978-1-61779-382-0_2 . Methods in Molecular Biology

Exercise as a beneficial adjunct therapy during Doxorubicin treatment-Role of mitochondria in cardioprotection

Ascensão, A., International Journal of Cardiology. 4 - 10. 1. 156. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84858070585&partnerID=MN8TOARS . 10.1016/j.ijcard.2011.05.060 . International Journal of Cardiology

In vitro salicylate does not further impair aging-induced brain mitochondrial dysfunction

Marques-Aleixo, I., Toxicology. 51 - 59. 1. 302. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84866002199&partnerID=MN8TOARS . 10.1016/j.tox.2012.07.018 . Toxicology

Toxicity evaluation of some traditional African spices on breast cancer cells and isolated rat hepatic mitochondria

Choumessi, A.T., Food and Chemical Toxicology. 4199 - 4208. 11. 50. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84866522308&partnerID=MN8TOARS . 10.1016/j.fct.2012.08.008 . Food and Chemical Toxicology

Mitochondrial bioenergetics and drug-induced toxicity in a panel of mouse embryonic fibroblasts with mitochondrial DNA single nucleotide polymorphisms

Pereira, C.V., Toxicology and Applied Pharmacology. 167 - 181. 2. 264. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84866878955&partnerID=MN8TOARS . 10.1016/j.taap.2012.07.030 . Toxicology and Applied Pharmacology

Mitochondrial remodeling in cancer metabolism and survival: Potential for new therapies

Barbosa, I.A., Biochimica et Biophysica Acta - Reviews on Cancer. 238 - 254. 1. 1826. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84860808557&partnerID=MN8TOARS . 10.1016/j.bbcan.2012.04.005 . Biochimica et Biophysica Acta - Reviews on Cancer

Minocycline exerts uncoupling and inhibiting effects on mitochondrial respiration through adenine nucleotide translocase inhibition

Cuenca-Lopez, M.D., Pharmacological Research. 120 - 128. 1. 65. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84855986971&partnerID=MN8TOARS . 10.1016/j.phrs.2011.08.007 . Pharmacological Research

The contribution of oxidative stress to drug-induced organ toxicity and its detection in vitro and in vivo

Pereira, C.V., Expert Opinion on Drug Metabolism and Toxicology. 219 - 237. 2. 8. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84856086570&partnerID=MN8TOARS . 10.1517/17425255.2012.645536 . Expert Opinion on Drug Metabolism and Toxicology

Gender-dependent metabolic remodeling during heart preservation in cardioplegic celsior and histidine buffer solution

Alves, M.G., Journal of Cardiovascular Pharmacology. 151 - 157. 2. 59. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84857063384&partnerID=MN8TOARS . 10.1097/FJC.0b013e3182391d17 . Journal of Cardiovascular Pharmacology

Regulation and protection of mitochondrial physiology by sirtuins

Pereira, C.V., Mitochondrion. 66 - 76. 1. 12. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84856527254&partnerID=MN8TOARS . 10.1016/j.mito.2011.07.003 . Mitochondrion

Physical exercise as a possible strategy for brain protection: Evidence from mitochondrial-mediated mechanisms

Marques-Aleixo, I., Progress in Neurobiology. 149 - 162. 2. 99. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84867896217&partnerID=MN8TOARS . 10.1016/j.pneurobio.2012.08.002 . Progress in Neurobiology

Melatonin modulates autophagy through a redox-mediated action in female Syrian hamster Harderian gland controlling cell types and gland activity

Vega-Naredo, I., Journal of Pineal Research. 80 - 92. 1. 52. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-83555174326&partnerID=MN8TOARS . 10.1111/j.1600-079X.2011.00922.x . Journal of Pineal Research

Fatty Acid Oxidation and Cardiovascular Risk during Menopause: A Mitochondrial Connection?

Oliveira PJ; Carvalho RA; Portincasa P; Bonfrate L; Sardao VA, 2012. http://europepmc.org/abstract/med/22496981 . 10.1155/2012/365798 .

Epigenetic engineering to reverse the Parkinson's expression state

Valente, A.X.C.N., Parkinsonism and Related Disorders. 717 - 721. 6. 18. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84862191970&partnerID=MN8TOARS . 10.1016/j.parkreldis.2012.04.018 . Parkinsonism and Related Disorders

Erratum: Gender-dependent metabolic remodeling during heart preservation in cardioplegic celsior and histidine buffer solution (Journal of Cardiovascular Pharmacology (2012) 59 (151-157))

Alves, M.G., Journal of Cardiovascular Pharmacology. 2. 60. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84865613134&partnerID=MN8TOARS . 10.1097/FJC.0b013e31825cce63 . Journal of Cardiovascular Pharmacology

Mitochondrionopathy phenotype in doxorubicin-treated wistar rats depends on treatment protocol and is cardiac-specific

Pereira, G.C., PLoS ONE. 6. 7. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84862661781&partnerID=MN8TOARS . 10.1371/journal.pone.0038867 . PLoS ONE

Role of mitochondria in nonalcoholic fatty liver disease-from origin to propagation

Grattagliano, I., Clinical Biochemistry. 610 - 618. 9. 45. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84861230299&partnerID=MN8TOARS . 10.1016/j.clinbiochem.2012.03.024 . Clinical Biochemistry

Differentiation-dependent doxorubicin toxicity on h9c2 cardiomyoblasts

Branco, A.F., Cardiovascular Toxicology. 326 - 340. 4. 12. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84870546889&partnerID=MN8TOARS . 10.1007/s12012-012-9177-8 . Cardiovascular Toxicology

Involvement of mitochondrial and B-RAF/ERK signaling pathways in berberine-induced apoptosis in human melanoma cells

Burgeiro, A., Anti-Cancer Drugs. 507 - 518. 6. 22. 2011. http://www.scopus.com/inward/record.url?eid=2-s2.0-79958289658&partnerID=MN8TOARS . 10.1097/CAD.0b013e32834438f6 . Anti-Cancer Drugs

Berberine as a promising safe anti-cancer agent - is there a role for mitochondria?

Diogo, C.V., Current Drug Targets. 850 - 859. 6. 12. 2011. http://www.scopus.com/inward/record.url?eid=2-s2.0-79955619830&partnerID=MN8TOARS . 10.2174/138945011795528930 . Current Drug Targets

Sodium hydrosulfide improves the protective potential of the cardioplegic histidine buffer solution

Alves, M.G., European Journal of Pharmacology. 60 - 67. 1. 654. 2011. http://www.scopus.com/inward/record.url?eid=2-s2.0-78951491593&partnerID=MN8TOARS . 10.1016/j.ejphar.2010.12.010 . European Journal of Pharmacology

Substrate selection in hearts subjected to ischemia/reperfusion: Role of cardioplegic solutions and gender

Alves, M.G., NMR in Biomedicine. 1029 - 1037. 9. 24. 2011. http://www.scopus.com/inward/record.url?eid=2-s2.0-80054064346&partnerID=MN8TOARS . 10.1002/nbm.1640 . NMR in Biomedicine

Metabolic remodeling during H9c2 myoblast differentiation: Relevance for in vitro toxicity studies

Pereira, S.L., Cardiovascular Toxicology. 180 - 190. 2. 11. 2011. http://www.scopus.com/inward/record.url?eid=2-s2.0-79958056642&partnerID=MN8TOARS . 10.1007/s12012-011-9112-4 . Cardiovascular Toxicology

Mitochondria as a drug target in health and disease

Oliveira, P.J., Current Drug Targets. 6. 12. 2011. http://www.scopus.com/inward/record.url?eid=2-s2.0-79955623985&partnerID=MN8TOARS . 10.2174/138945011795528912 . Current Drug Targets

Mitochondria as a target for exercise-induced cardioprotection

Ascensão, A., Current Drug Targets. 860 - 871. 6. 12. 2011. http://www.scopus.com/inward/record.url?eid=2-s2.0-79955608557&partnerID=MN8TOARS . 10.2174/138945011795529001 . Current Drug Targets

Mitochondria from distinct tissues are differently affected by 17ß-estradiol and tamoxifen

Moreira, P.I., Journal of Steroid Biochemistry and Molecular Biology. 8 - 16. 1-2. 123. 2011. http://www.scopus.com/inward/record.url?eid=2-s2.0-78650578395&partnerID=MN8TOARS . 10.1016/j.jsbmb.2010.09.004 . Journal of Steroid Biochemistry and Molecular Biology

Mitochondria in chronic liver disease

Grattagliano, I., Current Drug Targets. 879 - 893. 6. 12. 2011. http://www.scopus.com/inward/record.url?eid=2-s2.0-79955606583&partnerID=MN8TOARS . 10.2174/138945011795528877 . Current Drug Targets

Mitochondrial tolerance to drugs and toxic agents in ageing and disease

Suski, J., Current Drug Targets. 827 - 849. 6. 12. 2011. http://www.scopus.com/inward/record.url?eid=2-s2.0-79955592779&partnerID=MN8TOARS . 10.2174/138945011795529029 . Current Drug Targets

Nimesulide interaction with membrane model systems: Are membrane physical effects involved in nimesulide mitochondrial toxicity?

Monteiro, J.P., Toxicology in Vitro. 1215 - 1223. 6. 25. 2011. http://www.scopus.com/inward/record.url?eid=2-s2.0-79960964709&partnerID=MN8TOARS . 10.1016/j.tiv.2011.05.014 . Toxicology in Vitro

Differential effects of p,p'-DDE on testis and liver mitochondria:Implications for reproductive toxicology

Mota, P.C., Reproductive Toxicology. 80 - 85. 1. 31. 2011. http://www.scopus.com/inward/record.url?eid=2-s2.0-79551613557&partnerID=MN8TOARS . 10.1016/j.reprotox.2010.09.010 . Reproductive Toxicology

Re-wiring the circuit: Mitochondria as a pharmacological target in liver disease

Diogo, C.V., Current Medicinal Chemistry. 5448 - 5465. 35. 18. 2011. http://www.scopus.com/inward/record.url?eid=2-s2.0-82255173714&partnerID=MN8TOARS . 10.2174/092986711798194432 . Current Medicinal Chemistry

Drug-induced cardiac mitochondrial toxicity and protection: From doxorubicin to carvedilol

Pereira, G.C., Current Pharmaceutical Design. 2113 - 2129. 20. 17. 2011. http://www.scopus.com/inward/record.url?eid=2-s2.0-80052226370&partnerID=MN8TOARS . 10.2174/138161211796904812 . Current Pharmaceutical Design

Endurance training reverts heart mitochondrial dysfunction, permeability transition and apoptotic signaling in long-term severe hyperglycemia

Lumini-Oliveira, J., Mitochondrion. 54 - 63. 1. 11. 2011. http://www.scopus.com/inward/record.url?eid=2-s2.0-78650035561&partnerID=MN8TOARS . 10.1016/j.mito.2010.07.005 . Mitochondrion

Erratum: Isoproterenol cytotoxicity is dependent on the differentiation state of the cardiomyoblast H9c2 cell line (Cardiovascular Toxicology DOI: 10.1007/s12012-011-9111-5)

Branco, A.F., Cardiovascular Toxicology. 3. 11. 2011. http://www.scopus.com/inward/record.url?eid=2-s2.0-80054890288&partnerID=MN8TOARS . 10.1007/s12012-011-9131-1 . Cardiovascular Toxicology

Interaction of carbonylcyanide p-trifluoromethoxyphenylhydrazone (FCCP) with lipid membrane systems: A biophysical approach with relevance to mitochondrial uncoupling

Monteiro, J.P., Journal of Bioenergetics and Biomembranes. 287 - 298. 3. 43. 2011. http://www.scopus.com/inward/record.url?eid=2-s2.0-79959768623&partnerID=MN8TOARS . 10.1007/s10863-011-9359-2 . Journal of Bioenergetics and Biomembranes

Isoproterenol cytotoxicity is dependent on the differentiation state of the cardiomyoblast H9c2 cell line

Branco, A.F., Cardiovascular Toxicology. 191 - 203. 3. 11. 2011. http://www.scopus.com/inward/record.url?eid=2-s2.0-80054914028&partnerID=MN8TOARS . 10.1007/s12012-011-9111-5 . Cardiovascular Toxicology

Lipophilic caffeic and ferulic acid derivatives presenting cytotoxicity against human breast cancer cells

Serafim, T.L., Chemical Research in Toxicology. 763 - 774. 5. 24. 2011. http://www.scopus.com/inward/record.url?eid=2-s2.0-79956157475&partnerID=MN8TOARS . 10.1021/tx200126r . Chemical Research in Toxicology

Acute exercise protects against calcium-induced cardiac mitochondrial permeability transition pore opening in doxorubicin-treated rats

Ascensão, A., Clinical Science. 37 - 49. 1. 120. 2011. http://www.scopus.com/inward/record.url?eid=2-s2.0-78650871083&partnerID=MN8TOARS . 10.1042/CS20100254 . Clinical Science

Anti-apoptotic protection afforded by cardioplegic celsior and histidine buffer solutions to hearts subjected to ischemia and ischemia/reperfusion

Alves, M.G., Journal of Cellular Biochemistry. 3872 - 3881. 12. 112. 2011. http://www.scopus.com/inward/record.url?eid=2-s2.0-80055000219&partnerID=MN8TOARS . 10.1002/jcb.23320 . Journal of Cellular Biochemistry

Dimethylaminopyridine derivatives of lupane triterpenoids are potent disruptors of mitochondrial structure and function

Holy, J., Bioorganic and Medicinal Chemistry. 6080 - 6088. 16. 18. 2010. http://www.scopus.com/inward/record.url?eid=2-s2.0-77955472585&partnerID=MN8TOARS . 10.1016/j.bmc.2010.06.075 . Bioorganic and Medicinal Chemistry

Electrochemical oxidation of sanguinarine and of its oxidation products at a glassy carbon electrode - relevance to intracellular effects

Diculescu, V.C., Electroanalysis. 113 - 120. 1. 22. 2010. http://www.scopus.com/inward/record.url?eid=2-s2.0-72649099240&partnerID=MN8TOARS . 10.1002/elan.200900367 . Electroanalysis

Erratum: Nitrogen compounds prevent H9c2 myoblast oxidative stress-induced mitochondrial dysfunction and cell death (Cardiovascular Toxicology (2010) 10 (51-65) DOI:10.1007/s12012-010-9062-2)

Silva, J.P., Cardiovascular Toxicology. 2. 10. 2010. http://www.scopus.com/inward/record.url?eid=2-s2.0-77956395509&partnerID=MN8TOARS . 10.1007/s12012-010-9067-x . Cardiovascular Toxicology

Long-term hyperglycaemia decreases gastrocnemius susceptibility to permeability transition

Lumini-Oliveira, J., European Journal of Clinical Investigation. 319 - 329. 4. 40. 2010. http://www.scopus.com/inward/record.url?eid=2-s2.0-77949664613&partnerID=MN8TOARS . 10.1111/j.1365-2362.2010.02267.x . European Journal of Clinical Investigation

Biapigenin modulates the activity of the adenine nucleotide translocator in isolated rat brain mitochondria

Silva, B.A., Neurotoxicity Research. 75 - 90. 1. 17. 2010. http://www.scopus.com/inward/record.url?eid=2-s2.0-77449110345&partnerID=MN8TOARS . 10.1007/s12640-009-9082-5 . Neurotoxicity Research

Nitrogen compounds prevent h9c2 myoblast oxidative stress-induced mitochondrial dysfunction and cell death.

Silva JP; Sardão VA; Coutinho OP; Oliveira PJ; Olveira PJ, 2010. http://europepmc.org/abstract/med/20119745 . 10.1007/s12012-010-9062-2 .

Sub-chronic administration of doxorubicin to Wistar rats results in oxidative stress and unaltered apoptotic signaling in the lung

Machado, N.G., Chemico-Biological Interactions. 478 - 486. 3. 188. 2010. http://www.scopus.com/inward/record.url?eid=2-s2.0-78149466319&partnerID=MN8TOARS . 10.1016/j.cbi.2010.09.027 . Chemico-Biological Interactions

Parabens in male infertility-Is there a mitochondrial connection?

Tavares, R.S., Reproductive Toxicology. 1 - 7. 1. 27. 2009. http://www.scopus.com/inward/record.url?eid=2-s2.0-58749116602&partnerID=MN8TOARS . 10.1016/j.reprotox.2008.10.002 . Reproductive Toxicology

Testicular mitochondrial alterations in untreated streptozotocin-induced diabetic rats

Amaral, S., Mitochondrion. 41 - 50. 1. 9. 2009. http://www.scopus.com/inward/record.url?eid=2-s2.0-60249101037&partnerID=MN8TOARS . 10.1016/j.mito.2008.11.005 . Mitochondrion

Can drug safety be predicted and animal experiments reduced by using isolated mitochondrial fractions?

Pereira, S.P.; Pereira SP; Pereira GC; Moreno AJ; Oliveira PJ, ATLA Alternatives to Laboratory Animals. 355 - 365. 4. 37. 2009. http://www.scopus.com/inward/record.url?eid=2-s2.0-70449604749&partnerID=MN8TOARS . ATLA Alternatives to Laboratory Animals

Doxorubicin: The good, the bad and the ugly effect

Carvalho, C., Current Medicinal Chemistry. 3267 - 3285. 25. 16. 2009. http://www.scopus.com/inward/record.url?eid=2-s2.0-70450215499&partnerID=MN8TOARS . 10.2174/092986709788803312 . Current Medicinal Chemistry

Electrochemical oxidation of berberine and of its oxidation products at a glassy carbon electrode

Diculescu, V.C., Electroanalysis. 1027 - 1034. 9. 21. 2009. http://www.scopus.com/inward/record.url?eid=2-s2.0-66649083195&partnerID=MN8TOARS . 10.1002/elan.200804516 . Electroanalysis

Endurance training improves gastrocnemius mitochondrial function despite increased susceptibility to permeability transition

Lumini-Oliveira, J., Mitochondrion. 454 - 462. 6. 9. 2009. http://www.scopus.com/inward/record.url?eid=2-s2.0-70449133441&partnerID=MN8TOARS . 10.1016/j.mito.2009.08.005 . Mitochondrion

Investigating drug-induced mitochondrial toxicity: A biosensor to increase drug safety?

Pereira, C.V., Current Drug Safety. 34 - 54. 1. 4. 2009. http://www.scopus.com/inward/record.url?eid=2-s2.0-63249131066&partnerID=MN8TOARS . 10.2174/157488609787354440 . Current Drug Safety

Morphological alterations induced by doxorubicin on H9c2 myoblasts: Nuclear, mitochondrial, and cytoskeletal targets

Sardão, V.A., Cell Biology and Toxicology. 227 - 243. 3. 25. 2009. http://www.scopus.com/inward/record.url?eid=2-s2.0-67349167673&partnerID=MN8TOARS . 10.1007/s10565-008-9070-1 . Cell Biology and Toxicology

Mitochondrial bioenergetics of testicular cells from the domestic cat (Felis catus)-A model for endangered species

Mota, P., Reproductive Toxicology. 111 - 116. 2. 27. 2009. http://www.scopus.com/inward/record.url?eid=2-s2.0-62549148154&partnerID=MN8TOARS . 10.1016/j.reprotox.2009.01.008 . Reproductive Toxicology

Mitochondrial preservation in celsior versus histidine buffer solution during cardiac Ischemia and reperfusion

Alves, M.G., Cardiovascular Toxicology. 185 - 193. 4. 9. 2009. http://www.scopus.com/inward/record.url?eid=2-s2.0-71949090655&partnerID=MN8TOARS . 10.1007/s12012-009-9052-4 . Cardiovascular Toxicology

Mitochondrial toxicity of the phyotochemicals daphnetoxin and daphnoretin - Relevance for possible anti-cancer application

Diogo, C.V., Toxicology in Vitro. 772 - 779. 5. 23. 2009. http://www.scopus.com/inward/record.url?eid=2-s2.0-67649401716&partnerID=MN8TOARS . 10.1016/j.tiv.2009.04.002 . Toxicology in Vitro

Mitochondrial involvement in cardiac apoptosis during ischemia and reperfusion: can we close the box?

Machado NG; Alves MG; Carvalho RA; Oliveira PJ, 2009. http://europepmc.org/abstract/med/19855945 . 10.1007/s12012-009-9055-1 .

Doxorubicin-induced mitochondrial dysfunction is secondary to nuclear p53 activation in H9c2 cardiomyoblasts

Sardão, V.A., Cancer Chemotherapy and Pharmacology. 811 - 827. 4. 64. 2009. http://www.scopus.com/inward/record.url?eid=2-s2.0-68149169047&partnerID=MN8TOARS . 10.1007/s00280-009-0932-x . Cancer Chemotherapy and Pharmacology

Inhibition of the adenine nucleotide translocator by N-acetyl perfluorooctane sulfonamides in vitro

O'Brien, T.M., Toxicology and Applied Pharmacology. 184 - 195. 2. 227. 2008. http://www.scopus.com/inward/record.url?eid=2-s2.0-38949127988&partnerID=MN8TOARS . 10.1016/j.taap.2007.10.016 . Toxicology and Applied Pharmacology

Mechanisms of berberine (Natural Yellow 18) - Induced mitochondrial dysfunction: Interaction with the adenine nucleotide translocator

Pereira, C.V., Toxicological Sciences. 408 - 417. 2. 105. 2008. http://www.scopus.com/inward/record.url?eid=2-s2.0-51849122083&partnerID=MN8TOARS . 10.1093/toxsci/kfn131 . Toxicological Sciences

Quercetin, kaempferol and biapigenin from hypericum perforatum are neuroprotective against excitotoxic insults

Silva, B., Neurotoxicity Research. 265 - 279. 3-4. 13. 2008. http://www.scopus.com/inward/record.url?eid=2-s2.0-55249095521&partnerID=MN8TOARS . 10.1007/BF03033510 . Neurotoxicity Research

Sanguinarine cytotoxicity on mouse melanoma K1735-M2 cells-Nuclear vs. mitochondrial effects

Serafim, T.L., Biochemical Pharmacology. 1459 - 1475. 11. 76. 2008. http://www.scopus.com/inward/record.url?eid=2-s2.0-55949119796&partnerID=MN8TOARS . 10.1016/j.bcp.2008.07.013 . Biochemical Pharmacology

Testicular aging involves mitochondrial dysfunction as well as an increase in UCP2 levels and proton leak

Amaral, S., FEBS Letters. 4191 - 4196. 30. 582. 2008. http://www.scopus.com/inward/record.url?eid=2-s2.0-57649108974&partnerID=MN8TOARS . 10.1016/j.febslet.2008.11.020 . FEBS Letters

Beneficial effects of exercise on muscle mitochondrial function in diabetes mellitus

Lumini, J.A., Sports Medicine. 735 - 750. 9. 38. 2008. http://www.scopus.com/inward/record.url?eid=2-s2.0-49949103399&partnerID=MN8TOARS . 10.2165/00007256-200838090-00003 . Sports Medicine

Complex formation between heptakis(2,6-di-O-methyl)-ß-cyclodextrin and cyclopentadienyl molybdenum(II) dicarbonyl complexes: Structural studies and cytotoxicity evaluations

Pereira, C.C.L., Organometallics. 4948 - 4956. 19. 27. 2008. http://www.scopus.com/inward/record.url?eid=2-s2.0-54249115357&partnerID=MN8TOARS . 10.1021/om800413w . Organometallics

Different concentrations of berberine result in distinct cellular localization patterns and cell cycle effects in a melanoma cell line

Serafim, T.L., Cancer Chemotherapy and Pharmacology. 1007 - 1018. 6. 61. 2008. http://www.scopus.com/inward/record.url?eid=2-s2.0-41049098849&partnerID=MN8TOARS . 10.1007/s00280-007-0558-9 . Cancer Chemotherapy and Pharmacology

Doxorubicin increases the susceptibility of brain mitochondria to Ca2+-induced permeability transition and oxidative damage

Cardoso, S., Free Radical Biology and Medicine. 1395 - 1402. 10. 45. 2008. http://www.scopus.com/inward/record.url?eid=2-s2.0-54349099428&partnerID=MN8TOARS . 10.1016/j.freeradbiomed.2008.08.008 . Free Radical Biology and Medicine

Disruption of hepatic mitochondrial bioenergetics is not a primary mechanism for the toxicity of methoprene - relevance for toxicological assessment.

Monteiro JP; Oliveira PJ; Moreno AJ; Jurado AS, 2008. http://europepmc.org/abstract/med/18511104 . 10.1016/j.chemosphere.2008.04.024 .

Drug-induced mitochondrial dysfunction in cardiac and skeletal muscle injury.

Sardão VA; Pereira SL; Oliveira PJ, 2008. http://europepmc.org/abstract/med/18324876 . 10.1517/14740338.7.2.129 .

Diabetes and the impairment of reproductive function: Possible role of mitochondria and reactive oxygen species

Amaral, S., Current Diabetes Reviews. 46 - 54. 1. 4. 2008. http://www.scopus.com/inward/record.url?eid=2-s2.0-38949101210&partnerID=MN8TOARS . 10.2174/157339908783502398 . Current Diabetes Reviews

Unaltered hepatic oxidative phosphorylation and mitochondrial permeability transition in Wistar rats treated with nimesulide: Relevance for nimesulide toxicity characterization

Moreno, A.J., Journal of Biochemical and Molecular Toxicology. 53 - 61. 2. 21. 2007. http://www.scopus.com/inward/record.url?eid=2-s2.0-34247399590&partnerID=MN8TOARS . 10.1002/jbt.20159 . Journal of Biochemical and Molecular Toxicology

Mitochondrially targeted effects of berberine [Natural Yellow 18, 5,6-dihydro-9,10-dimethoxybenzo(g)-1,3-benzodioxolo(5,6-a) quinolizinium] on K1735-M2 mouse melanoma cells: Comparison with direct effects on isolated mitochondrial fractions

Pereira, G.C., Journal of Pharmacology and Experimental Therapeutics. 636 - 649. 2. 323. 2007. http://www.scopus.com/inward/record.url?eid=2-s2.0-35548974344&partnerID=MN8TOARS . 10.1124/jpet.107.128017 . Journal of Pharmacology and Experimental Therapeutics

Response [2]

Oliveira, P.J., Journal of Biochemical and Molecular Toxicology. 6. 21. 2007. http://www.scopus.com/inward/record.url?eid=2-s2.0-36749085079&partnerID=MN8TOARS . 10:1002/jbt . Journal of Biochemical and Molecular Toxicology

Vital imaging of H9c2 myoblasts exposed to tert-butylhydroperoxide - Characterization of morphological features of cell death

Sardão, V.A., BMC Cell Biology. 8. 2007. http://www.scopus.com/inward/record.url?eid=2-s2.0-33947598915&partnerID=MN8TOARS . 10.1186/1471-2121-8-11 . BMC Cell Biology

Inhibition of mitochondrial bioenergetics by carbaryl is only evident for higher concentrations - Relevance for carbaryl toxicity mechanisms

Moreno, A.J.M., Chemosphere. 404 - 411. 3. 66. 2007. http://www.scopus.com/inward/record.url?eid=2-s2.0-33751232011&partnerID=MN8TOARS . 10.1016/j.chemosphere.2006.06.030 . Chemosphere

Mitochondria as targets for neuronal protection against excitotoxicity: A role for phenolic compounds?

Silva, B.A., Central Nervous System Agents in Medicinal Chemistry. 205 - 222. 3. 7. 2007. http://www.scopus.com/inward/record.url?eid=2-s2.0-34548408654&partnerID=MN8TOARS . 10.2174/187152407781669152 . Central Nervous System Agents in Medicinal Chemistry

Vitamin E prevents hypobaric hypoxia-induced mitochondrial dysfunction in skeletal muscle

Magalhães, J., Clinical Science. 459 - 466. 11-12. 113. 2007. http://www.scopus.com/inward/record.url?eid=2-s2.0-36849067904&partnerID=MN8TOARS . 10.1042/CS20070075 . Clinical Science

Doxorubicin-induced thiol-dependent alteration of cardiac mitochondrial permeability transition and respiration

Oliveira, P.J., Biochemistry (Moscow). 194 - 199. 2. 71. 2006. http://www.scopus.com/inward/record.url?eid=2-s2.0-33645277082&partnerID=MN8TOARS . 10.1134/S000629790602012X . Biochemistry (Moscow)

Depletion of adenine nucleotide translocator protein in heart mitochondria from doxorubicin-treated rats - Relevance for mitochondrial dysfunction

Oliveira, P.J., Toxicology. 160 - 168. 2-3. 220. 2006. http://www.scopus.com/inward/record.url?eid=2-s2.0-33244492919&partnerID=MN8TOARS . 10.1016/j.tox.2005.12.009 . Toxicology

Decreased ANT content in Zucker fatty rats: Relevance for altered hepatic mitochondrial bioenergetics in steatosis

Teodoro, J., FEBS Letters. 2153 - 2157. 8. 580. 2006. http://www.scopus.com/inward/record.url?eid=2-s2.0-33645241135&partnerID=MN8TOARS . 10.1016/j.febslet.2006.02.078 . FEBS Letters

Pt(II) vs Pd(II) polyamine complexes as new anticancer drugs: A structure-activity study

Fiuza, S.M., Letters in Drug Design and Discovery. 149 - 151. 3. 3. 2006. http://www.scopus.com/inward/record.url?eid=2-s2.0-33645876182&partnerID=MN8TOARS . 10.2174/157018006776286989 . Letters in Drug Design and Discovery

Esterification prevents induction of the mitochondrial permeability transition by N-acetyl perfluorooctane sulfonamides

O'Brien, T.M., Chemical Research in Toxicology. 1305 - 1312. 10. 19. 2006. http://www.scopus.com/inward/record.url?eid=2-s2.0-33750209492&partnerID=MN8TOARS . 10.1021/tx060132r . Chemical Research in Toxicology

Endurance training limits the functional alterations of heart rat mitochondria submitted to in vitro anoxia-reoxygenation

Ascensão, A., International Journal of Cardiology. 169 - 178. 2. 109. 2006. http://www.scopus.com/inward/record.url?eid=2-s2.0-33646109584&partnerID=MN8TOARS . 10.1016/j.ijcard.2005.06.003 . International Journal of Cardiology

Effects of endurance training and acute doxorubicin treatment on rat heart mitochondrial alterations induced by in vitro anoxia-reoxygenation

Ascensão, A.; Ascensão A; Ferreira R; Oliveira PJ; Magalhães J, Cardiovascular Toxicology. 159 - 171. 3-4. 6. 2006. http://www.scopus.com/inward/record.url?eid=2-s2.0-33947101036&partnerID=MN8TOARS . 10.1385/ct:6:3:159 . Cardiovascular Toxicology

Moderate endurance training prevents doxorubicin-induced in vivo mitochondriopathy and reduces the development of cardiac apoptosis

Ascensão, A., American Journal of Physiology - Heart and Circulatory Physiology. 2 58-2. 289. 2005. http://www.scopus.com/inward/record.url?eid=2-s2.0-23744489541&partnerID=MN8TOARS . 10.1152/ajpheart.01249.2004 . American Journal of Physiology - Heart and Circulatory Physiology

Are the antioxidant properties of carvedilol important for the protection of cardiac mitochondria?

Oliveira, P.J., Current Vascular Pharmacology. 147 - 158. 2. 3. 2005. http://www.scopus.com/inward/record.url?eid=2-s2.0-18144430946&partnerID=MN8TOARS . 10.2174/1570161053586903 . Current Vascular Pharmacology

Dietary vitamin E decreases doxorubicin-induced oxidative stress without preventing mitochondrial dysfunction

Berthiaume, J.M., Cardiovascular Toxicology. 257 - 267. 3. 5. 2005. http://www.scopus.com/inward/record.url?eid=2-s2.0-27144450968&partnerID=MN8TOARS . 10.1385/CT:5:3:257 . Cardiovascular Toxicology

Bile acids are toxic for isolated cardiac mitochondria: a possible cause for hepatic-derived cardiomyopathies?

Ferreira M; Coxito PM; Sardão VA; Palmeira CM; Oliveira PJ; Ferreira, M., Cardiovascular toxicology. 63 - 73. 1. 5. 2005. http://europepmc.org/abstract/med/15738586 . 10.1385/ct:5:1:063 . Cardiovascular toxicology

Cardiac mitochondrial alterations observed in hyperglycaemic rats--what can we learn from cell biology?

Oliveira PJ; Oliveira, P.J., Current diabetes reviews. 11 - 21. 1. 1. 2005. http://europepmc.org/abstract/med/18220578 . 10.2174/1573399052952578 . Current diabetes reviews

Advantages in the use of carvedilol versus propranolol for the protection of cardiac mitochondrial function.

Oliveira PJ; Rolo AP; Sardão VA; Monteiro P; Gonçalves L; Providência LA; Palmeira CM; Moreno AJ; Oliveira, P.J., Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology. 1291 - 1298. 10. 23. 2004. http://europepmc.org/abstract/med/15641294 . Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology

Vitamin E or coenzyme Q10 administration is not fully advantageous for heart mitochondrial function in diabetic goto kakizaki rats

Oliveira, P.J., Mitochondrion. 337 - 345. 6. 3. 2004. http://www.scopus.com/inward/record.url?eid=2-s2.0-1942484378&partnerID=MN8TOARS . 10.1016/j.mito.2004.02.005 . Mitochondrion

Carvedilol-mediated antioxidant protection against doxorubicin-induced cardiac mitochondrial toxicity

Oliveira, P.J., Toxicology and Applied Pharmacology. 159 - 168. 2. 200. 2004. http://www.scopus.com/inward/record.url?eid=2-s2.0-5144227343&partnerID=MN8TOARS . 10.1016/j.taap.2004.04.005 . Toxicology and Applied Pharmacology

Carvedilol Inhibits the Mitochondrial Permeability Transition by an Antioxidant Mechanism

Oliveira, P.J., Cardiovascular Toxicology. 11 - 20. 1. 4. 2004. http://www.scopus.com/inward/record.url?eid=2-s2.0-1942486470&partnerID=MN8TOARS . 10.1385/CT:4:1:11 . Cardiovascular Toxicology

Calcium-dependent mitochondrial permeability transition is augmented in the kidney of Goto-Kakizaki diabetic rat

Oliveira, P.J., Diabetes/Metabolism Research and Reviews. 131 - 136. 2. 20. 2004. http://www.scopus.com/inward/record.url?eid=2-s2.0-1842853998&partnerID=MN8TOARS . 10.1002/dmrr.423 . Diabetes/Metabolism Research and Reviews

Diabetes induces metabolic adaptations in rat liver mitochondria: Role of coenzyme Q and cardiolipin contents

Ferreira, F.M., Biochimica et Biophysica Acta - Molecular Basis of Disease. 113 - 120. 2. 1639. 2003. http://www.scopus.com/inward/record.url?eid=2-s2.0-0642345079&partnerID=MN8TOARS . 10.1016/j.bbadis.2003.08.001 . Biochimica et Biophysica Acta - Molecular Basis of Disease

Chronic cholestasis and cardiac mitochondrial function in wistar rats: A model for cardiovascular alterations in chronic liver disease? | Colestase crónica e funçá~o mitocondrial cardíaca em ratos wistar: Um modelo para alterações cardiovasculares no contexto de doenças hepáticas crónicas?

Oliveira, P.J., Revista Portuguesa de Cardiologia. 67 - 75. 1. 22. 2003. http://www.scopus.com/inward/record.url?eid=2-s2.0-0344951202&partnerID=MN8TOARS . Revista Portuguesa de Cardiologia

Chenodexycholate induction of mitochondrial permeability transition pore is associated with increased membrane fluidity and cytochrome c release: Protective role of carvedilol

Rolo, A.P., Mitochondrion. 305 - 311. 4. 2. 2003. http://www.scopus.com/inward/record.url?eid=2-s2.0-0037347309&partnerID=MN8TOARS . 10.1016/S1567-7249(03)00007-2 . Mitochondrion

Cardiac mitochondrial calcium loading capacity is severely affected after chronic cholestasis in Wistar rats

Oliveira, P.J.; Oliveira PJ; Rolo AP; Seiça R; Santos MS; Palmeira CM; Moreno AJ, Journal of Investigative Medicine. 86 - 94. 2. 51. 2003. http://www.scopus.com/inward/record.url?eid=2-s2.0-0037338705&partnerID=MN8TOARS . Journal of Investigative Medicine

Protection against post-ischemic mitochondrial injury in rat liver by silymarin or TUDC

Rolo, A.P., Hepatology Research. 217 - 224. 3. 26. 2003. http://www.scopus.com/inward/record.url?eid=2-s2.0-0042167601&partnerID=MN8TOARS . 10.1016/S1386-6346(03)00108-6 . Hepatology Research

Enhanced permeability transition explains the reduced calcium uptake in cardiac mitochondria from streptozotocin-induced diabetic rats

Oliveira, P.J., FEBS Letters. 511 - 514. 3. 554. 2003. http://www.scopus.com/inward/record.url?eid=2-s2.0-0242541631&partnerID=MN8TOARS . 10.1016/S0014-5793(03)01233-X . FEBS Letters

Reduction in cardiac mitochondrial calcium loading capacity is observable during a-naphthylisothiocyanate-induced acute cholestasis: A clue for hepatic-derived cardiomyopathies?

Oliveira, P.J., Biochimica et Biophysica Acta - Molecular Basis of Disease. 39 - 45. 1. 1637. 2003. http://www.scopus.com/inward/record.url?eid=2-s2.0-0037454702&partnerID=MN8TOARS . 10.1016/S0925-4439(02)00212-0 . Biochimica et Biophysica Acta - Molecular Basis of Disease

Histological changes and impairment of liver mitochondrial bioenergetics after long-term treatment with a-naphthyl-isothiocyanate (ANIT)

Palmeira, C.M., Toxicology. 185 - 196. 3. 190. 2003. http://www.scopus.com/inward/record.url?eid=2-s2.0-0042133192&partnerID=MN8TOARS . 10.1016/S0300-483X(03)00163-X . Toxicology

Carvedilol: Relation between antioxidant activity and inhibition of the mitochondrial permeability transition | Carvedilol: Relação entre a actividade antioxidante e inibição da transição de permeabilidade mitocondrial

Oliveira, P.J., Revista Portuguesa de Cardiologia. 55 - 62. 1. 22. 2003. http://www.scopus.com/inward/record.url?eid=2-s2.0-0346034614&partnerID=MN8TOARS . Revista Portuguesa de Cardiologia

Pharmacological modulation of mitochondrial function during ischemia and reperfusion | Modulação farmacológica da função mitocondrial no contexto da isquemia e reperfusão

Monteiro, P., Revista Portuguesa de Cardiologia. 407 - 429. 3. 22. 2003. http://www.scopus.com/inward/record.url?eid=2-s2.0-0038795126&partnerID=MN8TOARS . Revista Portuguesa de Cardiologia

Chronic cholestasis and cardiac mitochondrial function in Wistar rats: a model for cardiovascular alterations in chronic liver disease?

Oliveira PJ; Rolo AP; Seiça R; Santos MS; Palmeira CM; Moreno AJ, Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology. 2003. http://europepmc.org/abstract/med/12712811 . Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology

Carvedilol: relation between antioxidant activity and inhibition of the mitochondrial permeability transition.

Oliveira PJ; Esteves T; Rolo AP; Monteiro P; Gonçalves L; Palmeira CM; Moreno AJ, Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology. 2003. http://europepmc.org/abstract/med/12712810 . Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology

Mitochondria: role in ischemia, reperfusion and cell death.

Monteiro P; Oliveira PJ; Gonçalves L; Providência LA, Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology. 2003. http://europepmc.org/abstract/med/12769003 . Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology

Cholestasis induced by chronic treatment with alpha-naphthyl-isothiocyanate (ANIT) affects rat renal mitochondrial bioenergetics.

Ferreira FM; Oliveira PJ; Rolo AP; Santos MS; Moreno AJ; da Cunha MF; Seiça R; Palmeira CM; Ferreira, F.M., Archives of Toxicology. 194 - 200. 4. 77. 2003. http://europepmc.org/abstract/med/12698234 . Archives of Toxicology

Mitochondria: Role in ischemia, reperfusion and cell death | Mitocôndrias: Que papel na isquémia, reperfusão e morte celular?

Monteiro, P., Revista Portuguesa de Cardiologia. 233 - 254. 2. 22. 2003. http://www.scopus.com/inward/record.url?eid=2-s2.0-0037732545&partnerID=MN8TOARS . Revista Portuguesa de Cardiologia

Caffeine enhances the calcium-dependent cardiac mitochondrial permeability transition: Relevance for caffeine toxicity

Sardão, V.A., Toxicology and Applied Pharmacology. 50 - 56. 1. 179. 2002. http://www.scopus.com/inward/record.url?eid=2-s2.0-0037082662&partnerID=MN8TOARS . 10.1006/taap.2001.9334 . Toxicology and Applied Pharmacology

Disruption of mitochondrial calcium homeostasis after chronic a-naphthylisothiocyanate administration: Relevance for cholestasis

Rolo, A.P.; Rolo AP; Oliveira PJ; Seiça R; Santos MS; Moreno AJ; Palmeira CM, Journal of Investigative Medicine. 193 - 200. 3. 50. 2002. http://www.scopus.com/inward/record.url?eid=2-s2.0-0036092085&partnerID=MN8TOARS . Journal of Investigative Medicine

Impact of carvedilol on the mitochondrial damage induced by hypoxanthine and xantine oxidase - What role in myocardial ischemia and reperfusion? | Impacto do carvedilol sobre o dano mitocondrial induzido por hipoxantina/xantina oxidase - Que papel na isquemia e reperfusão do miocárdio?

Oliveira, P.J., Revista Portuguesa de Cardiologia. 1447 - 1455. 12. 21. 2002. http://www.scopus.com/inward/record.url?eid=2-s2.0-0036998602&partnerID=MN8TOARS . Revista Portuguesa de Cardiologia

Improved efficiency of hepatic mitochondrial function in rats with cholestasis induced by an acute dose of a-naphthylisothiocyanate

Rolo, A.P., Toxicology and Applied Pharmacology. 20 - 26. 1. 182. 2002. http://www.scopus.com/inward/record.url?eid=2-s2.0-0036070550&partnerID=MN8TOARS . 10.1006/taap.2002.9434 . Toxicology and Applied Pharmacology

Impact of diabetes on induction of the mitochondrial permeability transition.

Oliveira PJ; Rolo AP; Seiça R; Sardão V; Monteiro P; Gonçalves L; Providência L; et al, Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology. 759 - 766. 6. 21. 2002. http://europepmc.org/abstract/med/12194377 . Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology

Impact of carvedilol on the mitochondrial damage induced by hypoxanthine and xantine oxidase--what role in myocardial ischemia and reperfusion?

Oliveira PJ; Rolo AP; Monteiro P; Gonçalves L; Palmeira CM; Moreno AJ, Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology. 2002. http://europepmc.org/abstract/med/12621918 . Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology

Study of carvedilol by combined Raman spectroscopy and ab initio MO calculations

Marques, M.P.M., Journal of Raman Spectroscopy. 778 - 783. 10. 33. 2002. http://www.scopus.com/inward/record.url?eid=2-s2.0-0036773098&partnerID=MN8TOARS . 10.1002/jrs.916 . Journal of Raman Spectroscopy

Carvedilol in heart mitochondria - Protonophore or opener of the mitochondrial KATP channels?

Oliveira, P.J., Life Sciences. 123 - 132. 2. 69. 2001. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035371154&partnerID=MN8TOARS . 10.1016/S0024-3205(01)01109-2 . Life Sciences

Protective effect of carvedilol on chenodeoxycholate induction of the permeability transition pore

Rolo, A.P., Biochemical Pharmacology. 1449 - 1454. 11. 61. 2001. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035370544&partnerID=MN8TOARS . 10.1016/S0006-2952(01)00620-7 . Biochemical Pharmacology

Inhibitory effect of carvedilol in the high-conductance state of the mitochondrial permeability transition pore

Oliveira, P.J., European Journal of Pharmacology. 231 - 237. 3. 412. 2001. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035793307&partnerID=MN8TOARS . 10.1016/S0014-2999(01)00745-2 . European Journal of Pharmacology

Decreased susceptibility of heart mitochondria from diabetic GK rats to mitochondrial permeability transition induced by calcium phosphate

Oliveira, P.J.; Oliveira PJ; Rolo AP; Seiça R; Palmeira CM; Santos MS; Moreno AJ, Bioscience Reports. 45 - 53. 1. 21. 2001. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034905572&partnerID=MN8TOARS . 10.1023/a:1010482017540 . Bioscience Reports

Chenodeoxycholate is a potent inducer of the permeability transition pore in rat liver mitochondria

Rolo, A.P., Bioscience Reports. 73 - 80. 1. 21. 2001. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034899577&partnerID=MN8TOARS . 10.1023/A:1010438202519 . Bioscience Reports

Carvedilol reduces mitochondrial damage induced by hypoxanthine/xanthine oxidase: Relevance to hypoxia/reoxygenation injury

Oliveira, P.J., Cardiovascular Toxicology. 205 - 213. 3. 1. 2001. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035750084&partnerID=MN8TOARS . 10.1385/CT:1:3:205 . Cardiovascular Toxicology

Carvedilol inhibits the exogenous NADH dehydrogenase in rat heart mitochondria

Oliveira, P.J., Archives of Biochemistry and Biophysics. 279 - 285. 2. 374. 2000. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034652094&partnerID=MN8TOARS . 10.1006/abbi.1999.1624 . Archives of Biochemistry and Biophysics

Effects of carvedilol on isolated heart mitochondria: Evidence for a protonophoretic mechanism

Oliveira, P.J., Biochemical and Biophysical Research Communications. 82 - 87. 1. 276. 2000. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034675219&partnerID=MN8TOARS . 10.1006/bbrc.2000.3374 . Biochemical and Biophysical Research Communications

Bile acids affect liver mitochondrial bioenergetics: possible relevance for cholestasis therapy.

Rolo AP; Oliveira PJ; Moreno AJ; Palmeira CM, 2000. http://europepmc.org/abstract/med/10966524 . 10.1093/toxsci/57.1.177 .

All projects

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Information of exclusive responsibility of the researcher 17-12-2023 , from platform CIÊNCIAVITAE.

2023/03/01 - 2028/08/31

PAS GRAS - De-risking metabolic, environmental and behavioral determinants of obesity in children, adolescents and young adults

HORIZON-HLTH-2022-STAYHLTH- 101080329

Universidade de Coimbra

Funders: European Commission

2023/03/01 - 2027/02/28

EXCELScIOR

101087416

Researcher

Universidade de Coimbra

Funders: European Commission

2023/03/01 - 2024/08/31

Novas abordagens terapêuticas para a obesidade baseadas na sinalização dopaminérgica periférica

2022.05822.PTDC

Universidade de Coimbra

Funders: Fundação para a Ciência e a Tecnologia

2023/03/10 - 2024/09/09

Desferrização da ataxia de Friedreich com quelantes inovadores direcionados para a mitocôndria

2022.04633.PTDC

Universidade do Porto Faculdade de Ciências

Funders: Fundação para a Ciência e a Tecnologia

2022/01/15 - 2025/01/14

Human Neuronal Cells Differentiated from Urine-derived Stem Cells as a Platform for Personalized Medicine in Amyotrophic Lateral Sclerosis

PTDC/BTM-ORG/0055/2021

Universidade de Coimbra; Universidade de Coimbra Instituto de Investigação Clínica e Biomédica de Coimbra

Funders: Fundação para a Ciência e a Tecnologia

2022/01/01 - 2023/06/30

Mitocôndria como potencial mediador do dimorfismo sexual nas alterações pato-morfológicas da microglia e ansiedade causadas pelo stress pré-natal<br>

EXPL/MED-NEU/1002/2021

Universidade de Coimbra; CNC.IBILI

Funders: Fundação para a Ciência e a Tecnologia

2022/01/01 - 2023/06/30

Função da homeostasia tiol-mitocondrial na neurodegeneração: implicações para a esclerose lateral amiotrófica

EXPL/BTM-TEC/1407/2021

Universidade de Coimbra; CNC.IBILI

Funders: Fundação para a Ciência e a Tecnologia

2022/06/01 - 2023/05/31

Proof of Concept “MitoBOOST v2.0 - A Proof of Concept for the Use of Mitochondria-Targeted Polyphenols to Treat Non-Alcoholic Fatty Liver Disease

181226

Principal investigator

CIBB - Center for Innovative Biomedicine and Biotechnology

Funders: Agência para a Competitividade e Inovação IP

2021/01/01 - 2025/12/31

Centro de Inovação em Biomedicina e Biotecnologia - Laboratório Associado

LA/P/0058/2020

Universidade de Coimbra; Universidade Nova de Lisboa ¿Laboratório de Instrumentação Engenharia Biomédica e Física da Radiação; Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: Fundação para a Ciência e a Tecnologia

2021 - 2021

Summer with Science: Research, Development and Interdisciplinary Innovation in the Physiolopathology of Aging and Lifestyle-dependent Diseases

n.a.

Principal investigator

CIBB - Center for Innovative Biomedicine and Biotechnology

Funders: Fundação para a Ciência e a Tecnologia

2021/01/01 - 2023/12/31

Organelle-targeted Radiocomplexes for Auger Therapy of Cancer

PTDC/MED-QUI/1554/2020

Associação do Instituto Superior Técnico para a Investigação e Desenvolvimento; Centro de Ciências e Tecnologias Nucleares; Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: Fundação para a Ciência e a Tecnologia

2020/07/01 - 2023/06/30

Preservação do património natural e cultural e validação científica das práticas com plantas medicinais do Vale do Côa

COA/BRB/0019/2019

Universidade de Coimbra; CNC.IBILI; Instituto Politécnico de Bragança; Universidade de Aveiro

Funders: Fundação para a Ciência e a Tecnologia

2020 - 2020

Summer Course: Methodologies for Scientific Research – Interdisciplinary Research, Development and Innovation in Cell and Molecular Metabolism

15-20/7/245

Principal investigator

CIBB - Center for Innovative Biomedicine and Biotechnology

Funders: Fundação para a Ciência e a Tecnologia

2019/01/01 - 2024/12/31

Lifelong exercise: modulating immunometabolic pathways for decreasing cancer risk.

10/22

Universidade de Coimbra Centro de Neurociências e Biologia Celular; Universidade de Coimbra Unidade de Investigação e Desenvolvimento Química-Física Molecular; Universidade de Coimbra Centro de Investigação do Desporto e da Actividade Física; Unidade Local de Saúde de Coimbra EPE

Funders: Associação de Apoio ao Centro de Investigação em Meio Ambiente Genética e Oncobiologia

2019/01/01 - 2019/12/31

CNC. IBILI

UID/NEU/04539/2019

Universidade de Coimbra; Universidade Nova de Lisboa ¿Laboratório de Instrumentação Engenharia Biomédica e Física da Radiação; Universidade de Coimbra Instituto de Ciências Nucleares Aplicadas à Saúde; Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: Fundação para a Ciência e a Tecnologia

2018 - 2021

The Role of Visceral Fructose Metabolism in the Development of Non-alcoholic Fatty Liver Disease

02/SAICT/2017/028147

Researcher

Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: Fundação para a Ciência e a Tecnologia

2018 - 2021

MitoCIN- Hydroxycinnamic derivatives, methods and uses thereof, Intelectual Protection Support

Portugal2020/call 17/SI/2015/37586

Principal investigator

2018 - 2021

Development of mitochondriotropic antioxidants based on a hydroxybenzoic acid scaffold, Intelectual Protection Support

Portugal2020/call 04/SAICT/2017/037892

Principal investigator

2018 - 2021

VALORIZEBYPRODUCTS: Preclinical efficacy of sulforaphane or Brassica whole extract: a strategy to fight obesity and valorize Brassica byproducts

POCI-01-0145-FEDER-029152

Researcher

Universidade de Coimbra Centro de Neurociências e Biologia Celular; Universidade de Trás-os-Montes e Alto Douro

Funders: Fundação para a Ciência e a Tecnologia

2018 - 2021

Mito4ALS: Development of Novel Mitochondria-Targeted Antioxidants for Improving SOD1-Familial Amyotrophic Lateral Sclerosis Phenotype

PTDC/MED-FAR/29391/2017

Researcher

Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: Fundação para a Ciência e a Tecnologia

2018/06/01 - 2022/01/31

O papel do metabolismo extra-hepático da frutose no desenvolvimento de doença hepática gordurosa não alcoólica

PTDC/BIA-BQM/28147/2017

Universidade de Coimbra Centro de Neurociências e Biologia Celular; Universidade de Aveiro; Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: Fundação para a Ciência e a Tecnologia

2018/06/01 - 2022/02/28

Eficácia pré-clínica do sulforafano ou do extrato total de Brássicas: uma estratégia para combater a obesidade e valorizar os subprodutos de Brássicas

PTDC/ASP-HOR/29152/2017

Universidade de Trás-os-Montes e Alto Douro; Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: Fundação para a Ciência e a Tecnologia

2018/07/26 - 2021/07/25

Uso de fitoquímicos redox-activos para desencadear a hormesis mitocondrial: Desenvolvimento de uma nova geração de ingredientes para a cosmética

PTDC/BIA-MOL/28607/2017

Universidade de Coimbra Centro de Neurociências e Biologia Celular; Universidade do Porto

Funders: Fundação para a Ciência e a Tecnologia

2018 - 2021

MitoSHIELD - Redox-active Phytochemicals Triggering Mitochondrial Hormesis: Developing a New Generation of Cosmetic Active Ingredients

PTDC/BTM-SAL/29297/2017

Principal investigator

Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: Fundação para a Ciência e a Tecnologia

2018 - 2021

Development and validation of innovative screening methods for mitochondrial health modulators

PTDC/BTM-SAL/29297/2017

Researcher

Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: Fundação para a Ciência e a Tecnologia

2018 - 2018

Mitochondrial-derived Peptides in Cell Homeostasis

FLAD Healthcare 2020

Principal investigator

Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: Fundação Luso-Americana

2017 - 2019

Tackling CANcer STEM CELls: A Challenge and an Opportunity to Advance in Anti-cancer Therapy

SAICTPAC/0022/2015

Researcher

Funders: Fundação para a Ciência e a Tecnologia

2017/01 - 2019/12

FOIE GRAS - Bioenergetic Remodeling in the Pathophysiology and Treatment of Non-Alcoholic Fatty Liver Disease

722619

Principal investigator

Funders: European Commission

2017/07 - 2020/06

mitoFOIE GRAS: Non-invasive Profiling of Mitochondrial Function in Non-Alcoholic Fatty Liver Disease

734719

Principal investigator

Funders: European Commission

2016/04/01 - 2019/09/30

EXERCITANDO O FUTURO: Exercício Voluntário Durante Diabetes Gestacional com uma Estratégia para Melhorar a Função Mitocondrial na Descendência

PTDC/DTP-DES/1082/2014

Universidade de Coimbra Centro de Neurociências e Biologia Celular; Universidade do Porto Faculdade de Desporto

Funders: Fundação para a Ciência e a Tecnologia

2016/04/01 - 2019/09/30

MitoBOOST: Uma Terapeutica de Nova Geração para a Doença de Fígado Gordo Não Alcoólico Baseado na Entrega Inteligente de Antioxidantes à Mitocôndria

PTDC/DTP-FTO/2433/2014

Universidade de Coimbra Centro de Neurociências e Biologia Celular; Universidade do Porto Faculdade de Ciências

Funders: Fundação para a Ciência e a Tecnologia

2016 - 2019

Exercising obesity - The Role of Exercise Against Endoplasmic Reticulum Stress in Obesity-induced Liver Disease

PTDC/DTP-DES/7087/2014

Researcher

Funders: Fundação para a Ciência e a Tecnologia

2015 - 2018

FishFree: A Contribution to the Validation of an Alternative Assay for Fish Lethal Ttesting

PTDC/AAG-TEC/4966/2014

Researcher

Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: Fundação para a Ciência e a Tecnologia

2015/10 - 2018/09

EXERCISING THE FUTURE: Voluntary Exercise During Gestational Diabetes as a Means to Improve Mitochondrial Function in the Offspring

grant.Provided by PTCRIS: 139707

Researcher

CNC.IBILI

Funders: Fundação para a Ciência e a Tecnologia

2015/10 - 2018/09

MitoBOOST: A Next-Generation Therapeutics for Non-Alcoholic Fatty Liver Disease Based on Smart Antioxidant Delivery to Mitochondria

grant.Provided by PTCRIS: 141059

Principal investigator

Funders: Fundação para a Ciência e a Tecnologia

2014 - 2015

Hypercholesterolemia as a risk factor for Alzheimer’s Disease: impact on nitric oxide bioavailability and bioactivity

8. Transnational Cooperation Agreement Project, CAPES/FCT 2013

Researcher

Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: Fundação para a Ciência e a Tecnologia

2013 - 2015

Pathophysiology of Persistent Doxorubicin Cardiotoxicity: a Mitochondrial-Epigenetics Link

PTDC/DTP-FTO/1180/2012

Principal investigator

Funders: Foundation for Science and Technology - Portugal

2011/01/01 - 2012/12/31

Strategic Project - LA 1 - 2011-2012

PEst-C/SAU/LA0001/2011

Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: Fundação para a Ciência e a Tecnologia

2011 - 2014

Protective Activity of SIRT3 Against Drug-induced Mitochondrial Dysfunction

PTDC/SAU-TOX/110952/2009

Principal investigator

Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: Foundation for Science and Technology - Portugal

2011/03/01 - 2014/08/31

Actividade Protectora da SIRT3 na Disfunção Mitocondrial Induzida por Fármacos

PTDC/SAU-TOX/110952/2009

Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: Fundação para a Ciência e a Tecnologia

2010/04 - 2013/03

Opening Pandora's Box for Active Anti-Breast Cancer Therapy - The Role of Selective Targeting to Mitochondria

101409

Principal investigator

Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: Fundação para a Ciência e a Tecnologia, I.P.

2010 - 2013

Role of Mitochondrial Physiology in Tumor Stem Cell Resistance to Chemotherapeutics

PTDC/QUI-BIQ/101052/2008

Principal investigator

Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: Foundation for Science and Technology - Portugal

2010 - 2013

Metabolism as a Modulator of Stem Cell Pluripotency and Differentiation

PTDC/EBB-EBI/101114/2008

Researcher

Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: Foundation for Science and Technology - Lisbon

2010 - 2013

Can Phytoestrogens be Safe and Effective Food Additives for Women During Menopause? - An In Vitro and In Vivo Approach to the problem

PTDC/AGR-ALI/108326/2008

Researcher

Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: Foundation for Science and Technology - Portugal

2010/05/01 - 2013/10/30

Clarificação do Papel Mitocondrial na Cardiotoxicidade da Doxorubicina Usando um Sistema de Perfusão de Corações Intactos - Papel de Diferentes Calendários de Tratamento com Doxorubicina

PTDC/SAU-OSM/104731/2008

Researcher

Instituto do Mar; University of Minnesota Twin Cities School of Medicine Duluth Campus; Universidade de Coimbra Centro de Inovação em Biomedicina e Biotecnologia; Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: Fundação para a Ciência e a Tecnologia; Fundação para a Ciência e a Tecnologia

2010 - 2013

Clarification of the Mitochondrial Role in the Cardiotoxicity of Doxorubicin Using a Whole Heart Perfusion System – Impact of Different Doxorubicin Treatment Regimens

PTDC/SAU-OSM/104731/2008

Researcher

Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: Fundação para a Ciência e a Tecnologia

2010 - 2012

MitocancerStem ¿ Role of Mitochondrial Physiology in Tumor Cell Resistance to Chemotherapeutics

FP7-People-2009-IEF 251850

Funders: European Commission

2010/04/01 - 2013/03/31

A Abertura da Caixa de Pandora Para uma Terapia Activa Anti-cancro da Mama - O Papel do Direccionamento Selectivo da Mitocôndria

PTDC/QUI-QUI/101409/2008

Universidade de Coimbra Centro de Neurociências e Biologia Celular; Mercer University School of Medicine; University of Minnesota Medical School - Duluth Campus; Universidade de Coimbra

Funders: Fundação para a Ciência e a Tecnologia

2010 - 2013

Role of Mitochondrial Physiology in Tumor Stem Cell Resistance to Chemotherapeutics

PTDC/QUI-BIQ/101052/2008

Funders: Foundation for Science and Technology - Portugal

2009 - 2011

Anticancer Activity of Novel Polyamine Pd(II) Complexes - A Multidisciplinary Study

PTDC/QUI/66701/2006

Researcher

Funders: Foundation for Science and Technology - Portugal

2007 - 2009

Influence of Cell Differentiation State on Apoptosis Induced by Isoproterenol on Embryonic Ventricular H9c2 Cells - Signalling Pathways Involved

PTDC/QUI/64358/2006

Researcher

Funders: Foundation for Science and Technology - Portugal

2007/09/15 - 2010/03/13

Novel Mitochondrial Mechanisms for the Cardioselective Toxicity of Doxorubicin

PTDC/SAU-OSM/64084/2006

Universidade do Porto Centro de Investigação em Actividade Física Saúde e Lazer; Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: Fundação para a Ciência e a Tecnologia

2005 - 2008

Development of Novel Anticancer Agents: Phenolic Derivatives of Natural and Synthetic Origin - Structure-Activity Relationships

POCTI/QUI/55631/2004

Researcher

Funders: Foundation for Science and Technology - Portugal

2005/07/01 - 2008/09/30

Influência das Soluções de Preservação para Transplante nos Perfis Metabólico e Imunológico Cardíacos

POCI/SAU-OBS/55802/2004

Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: Fundação para a Ciência e a Tecnologia

2005/10/15 - 2007/04/15

Desenvolvimento de Novos Agentes Anticancerígenos: Derivados Fenólicos de Origem Natural ou Sintética - Relações Estrutura-Actividade

POCI/QUI/55631/2004

Universidade de Coimbra; Universidade de Coimbra Unidade de Investigação e Desenvolvimento Química-Física Molecular; Universidade do Porto Faculdade de Farmácia; Instituto Politécnico do Porto Instituto Superior de Engenharia do Porto; Universidade do Porto Faculdade de Ciências

Funders: Fundação para a Ciência e a Tecnologia

2003/02/15 - 2006/10/14

ADRIAMYCIN - ASSOCIATED CARDIOMYOPATHIES - IMPACT OF METABOLIC THRESHOLDS IN SELECTIVE ORGAN TOXICITY AND DIFFERENTIAL ACTIVATION OF MITOCHONDRIAL ATP-SENSITIVE POTASSIUM CHANNELS

SFRH/BPD/8359/2002

Funders: Fundação para a Ciência e a Tecnologia

2000 - 2003

Mitochondria and diabetes: mitochondrial function in the brain and heart of non-insulin dependent animal models (Goto-Kakizaki)

POCTI/ESP/43642/1999

Researcher

Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: Fundação para a Ciência e a Tecnologia; Fundação para a Ciência e a Tecnologia

2000 - 2003

Mitochondria and diabetes: mitochondrial function in the brain and heart of non-insulin dependent animal models (Goto-Kakizaki)

POCTI/ESP/43642/1999

Researcher

Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: Fundação para a Ciência e a Tecnologia

2000/01/01 - 2003/01/31

UTILIZAÇÃO SISTEMÁTICA DE CARDIOMIÓCITOS E DE MITOCÔNDRIAS CARDÍACAS ISOLADAS COMO MODELO DE AVALIAÇÃO FARMACOLÓGICA E TOXICOLÓGICA DE FÁRMACOS COM ACÇÃO A NÍVEL CARDÍACO

PRAXIS XXI/BD/21494/99

Funders: Fundação para a Ciência e a Tecnologia

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