Ana Filipa Fernandes da Cruz

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PhD Student

Publications

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Information about journal articles, updated at 14-08-2022, from platform CIÊNCIAVITAE.

Nucleolin Overexpression Predicts Patient Prognosis While Providing a Framework for Targeted Therapeutic Intervention in Lung Cancer

Ângela Valério-Fernandes; Nuno A. Fonseca; Nélio Gonçalves; Ana F. Cruz; Marta I. Pereira; Ana C. Gregório; Vera Moura; et al, Cancers. 2217 - 2217. 9. 14. 2022. https://doi.org/10.3390/cancers14092217 . 10.3390/cancers14092217 . Cancers

Targeted liposomal doxorubicin/ceramides combinations: The importance to assess the nature of drug interaction beyond bulk tumor cells

Cruz, Ana Filipa; Fonseca, Nuno A.; Malheiro, Ana Rita; B. Melo, Joana; Gaspar, Maria Manuela; Fernandes, Rui; Moura, Vera; Simões, Sérgio; Moreira, João Nuno, European Journal of Pharmaceutics and Biopharmaceutics. 61 - 77. 172. 2022. http://dx.doi.org/10.1016/j.ejpb.2022.01.006 . 10.1016/j.ejpb.2022.01.006 . European Journal of Pharmaceutics and Biopharmaceutics

The Enhanced Efficacy of Intracellular Delivery of Doxorubicin/C6-Ceramide Combination Mediated by the F3 Peptide/Nucleolin System Is Supported by the Downregulation of the PI3K/Akt Pathway

Ana F. Cruz; Mariana B. Caleiras; Nuno A. Fonseca; Nélio Gonçalves; Vera M. Mendes; Susana F. Sampaio; Vera Moura; et al, Cancers. 3052 - 3052. 12. 13. 2021. https://doi.org/10.3390/cancers13123052 . 10.3390/cancers13123052 . Cancers

Cell surface Nucleolin represents a novel cellular target for neuroblastoma therapy

Brignole, Chiara; Bensa, Veronica; Fonseca, Nuno A.; Del Zotto, Genny; Bruno, Silvia; Cruz, Ana F.; Malaguti, Fabiana; et al, Journal of Experimental & Clinical Cancer Research. 1. 40. 2021. http://dx.doi.org/10.1186/s13046-021-01993-9 . 10.1186/s13046-021-01993-9 . Journal of Experimental & Clinical Cancer Research

Targeting Cancer Stem Cells and Non-Stem Cancer Cells: The Potential of Lipid- Based Nanoparticles

Cruz, Ana Filipa; Fonseca, Nuno Andre; Moura, Vera; Simoes, Sergio; Moreira, Joao Nuno, Current Pharmaceutical Design. 6563 - 6572. 43. 23. 2018. http://dx.doi.org/10.2174/1381612823666171115105252 . 10.2174/1381612823666171115105252 . Current Pharmaceutical Design

All projects

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Information of exclusive responsibility of the researcher 14-08-2022 , from platform CIÊNCIAVITAE.

2020/04 - 2020/06

COVID-19 Lab @ CNC / ViraVector

NA

Research Fellow

Universidade de Coimbra Centro de Neurociências e Biologia Celular

2017/07/01 - 2021/03/31

CANCEL_STEM_Estaminalidade das células do cancro: um desafio e uma oportunidade para avançar no tratamento em Oncologia¿

SAICTPAC/0022/2015 (POCI-01-0145-FEDER-016390)

Research Fellow

Universidade de Coimbra Centro de Neurociências e Biologia Celular

2017 -

HealthyAging 2020

CENTRO-01-0145-FEDER-000012

Research Fellow

CNC.IBILI; Universidade de Coimbra Centro de Neurociências e Biologia Celular

2016 - 2020

Towards a single therapy against triple negative breast cancer and neuroblastoma by nucleolin-mediated multicellular targeting with a synergistic drug combination.

EN/Med/0005/2015

Research Fellow

Universidade de Coimbra Centro de Neurociências e Biologia Celular

2013/02/01 - 2017/01/31

Insights into the mechanisms of dual targeted-triggered release lipid-based nanoparticles.

SFRH/BD/85554/2012

PhD Student Fellow

Universidade de Coimbra Centro de Neurociências e Biologia Celular; Universidade de Coimbra Faculdade de Farmácia

Funders: Fundação para a Ciência e a Tecnologia

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