Metabolism, Aging and Disease

Contraception, Endocrine Disruptors and Fertility


Endocrine-disrupting chemicals


Reproductive (Dys)function

Infertility diagnosis

Research lines

Impact assessment of endocrine-disrupting chemicals and lifestyle factors in fertility and offspring health

Efficacy and safety evaluation of contraceptive strategies (preclinical industry-driven projects)

Development and/or validation of new methodologies for the diagnosis of male infertility


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Information about journal articles, updated at 26-05-2024, from platform CIÊNCIAVITAE.

A ripple effect? The impact of obesity on sperm quality and function

Alfaiate, Maria Inês; Tavares, Renata Santos; Ramalho-Santos, João, 2024. Reproduction, Fertility and Development. 7. 36. 2024. . 10.1071/rd23215 . published Reproduction, Fertility and Development

It Takes Two to Tango: Environmentally-relevant doses of Mercury and Arsenic compromise human sperm functionality

Alfaiate, MIR; Carola, Carolina; Sousa, Ana Paula; Almeida-Santos, Teresa: AT Santos; Ramalho-Santos, João; Tavares, Renata, 2024. Chemosphere. 2024. submitted Chemosphere

In vitro effects of antidepressants on human sperm function

António Santos, Rita; Sousa, Ana Paula; Almeida-Santos, Teresa: AT Santos; Ramalho-Santos, João; Tavares, Renata S., 2024. Asian Journal of Andrology. 2024. published Asian Journal of Andrology

New Insights on Sperm Function in Male Infertility of Unknown Origin: A Multimodal Approach

Pacheco, Rita I.; Cristo, Maria I.; Anjo, Sandra I.; Silva, Andreia F.; Sousa, Maria Inês; Tavares, Renata S.; Sousa, Ana Paula; et al, 2023. Biomolecules. 10. 13. 2023. . 10.3390/biom13101462 . published Biomolecules

The role of sperm and oocyte in fetal programming: Is Lamarck making a comeback?

Tavares, Renata Santos; Ramalho-Santos, João, 2021. European Journal of Clinical Investigation. 2021. . 10.1111/eci.13521 . published European Journal of Clinical Investigation

Comparative in vitro study on the local tolerance and efficacy of benzalkonium chloride, myristalkonium chloride and nonoxynol-9 as active principles in vaginal contraceptives

Alfaiate, Maria Inês; António Santos, Rita; Silva, Andreia Filipa; Sousa, Ana Paula; Almeida-Santos, Teresa; Gendron, Célia; Jabbour, Violaine; et al, 2021. The European Journal of Contraception & Reproductive Health Care. 334 - 342. 4. 26. 2021. . 10.1080/13625187.2021.1900563 . The European Journal of Contraception & Reproductive Health Care

Environmental Impact on Male (In)Fertility via Epigenetic Route

Cescon, Matilde; Chianese, Rosanna; Tavares, Renata S., 2020. Journal of Clinical Medicine. 8. 9. 2020. . 10.3390/jcm9082520 . published Journal of Clinical Medicine

Can Antidiabetic Drugs Improve Male Reproductive (Dys)Function Associated with Diabetes?

Tavares, R.S.; Escada-Rebelo, S.; Sousa, M.I.; Silva, A.; Ramalho-Santos, J.; Amaral, S., 2019. Current Medicinal Chemistry. 4191 - 4222. 22. 26. 2019. . 10.2174/0929867325666181101111404 . published Current Medicinal Chemistry

Can we induce spermatogenesis in the domestic cat using an in vitro tissue culture approach?

Silva, Andreia F.; Escada-Rebelo, Sara; Amaral, Sandra; Tavares, Renata S.; Schlatt, Stefan; Ramalho-Santos, João; Mota, Paula C., 2018. PLOS ONE. 2. 13. 2018. . 10.1371/journal.pone.0191912 . published PLOS ONE

Antidiabetic therapies and male reproductive function: where do we stand?

Tavares, R S; Escada-Rebelo, S; Silva, A F; Sousa, M I; Ramalho-Santos, J; Amaral, S, 2018. Reproduction. R13 - R37. 1. 155. 2018. . 10.1530/rep-17-0390 . published Reproduction

Orchestration at the beginning: mitosis in sea urchin embryo

Abruzzese, Giselle A.; Tanpradit, Nae; Tavares, Renata S., 2017. Molecular Reproduction and Development. 1023 - 1023. 10. 84. 2017. . 10.1002/mrd.22854 . published Molecular Reproduction and Development

High glucose levels affect spermatogenesis: an in vitro approach

Tavares, Renata S.; Portela, Joana M. D.; Sousa, Maria I.; Mota, Paula C.; Ramalho-Santos, João; Amaral, Sandra, 2017. Reproduction, Fertility and Development. 7. 29. 2017. . 10.1071/rd15475 . published Reproduction, Fertility and Development

Alzheimer’s disease-related amyloid-ß1–42 peptide induces the loss of human sperm function

Tavares, R. S.; Martins, S.; Almeida-Santos, T.; Sousa, A. P.; Ramalho-Santos, J.; da Cruz e Silva, O. A., 2017. Cell and Tissue Research. 647 - 651. 3. 369. 2017. . 10.1007/s00441-017-2665-1 . published Cell and Tissue Research

Spermatogonial stem cell organization in felid testis as revealed by Dolichos biflorus lectin

Escada-Rebelo, S.; Silva, A. F.; Amaral, S.; Tavares, R. S.; Paiva, C.; Schlatt, S.; Ramalho-Santos, J.; Mota, P. C., 2016. Andrology. 1159 - 1168. 6. 4. 2016. . 10.1111/andr.12223 . published Andrology

The non-genomic effects of endocrine-disrupting chemicals on mammalian sperm

Tavares, R S; Escada-Rebelo, S; Correia, M; Mota, P C; Ramalho-Santos, J, 2016. REPRODUCTION. R1 - R13. 1. 151. 2016. . 10.1530/rep-15-0355 . published REPRODUCTION

Mitochondrial Functionality and Chemical Compound Action on Sperm Function

Amaral, S.; S. Tavares, R.; Baptista, M.; I. Sousa, M.; Silva, A.; Escada-Rebelo, S.; P. Paiva, C.; Ramalho-Santos, J., 2016. Current Medicinal Chemistry. 3575 - 3606. 31. 23. 2016. . 10.2174/0929867323666160425113518 . published Current Medicinal Chemistry

Light Microscopy of Male Reproductive Organs after CdCl2 Exposure: Focus on Morphometric Analysis of Testis and Sperm Parameters

Pereira, ML; Tavares, Renata; Garcia e Costa, F, 2015. International Journal of Scientific & Engineering Research. 39 - 41. 12. 6. 2015. published International Journal of Scientific & Engineering Research

High glucose concentrations per se do not adversely affect human sperm function in vitro.

Tavares, R S; Portela, J M D; Mota, P C; Ramalho-Santos, J; Amaral, S, 2015. REPRODUCTION. 77 - 84. 1. 150. 2015. . 10.1530/rep-15-0100 . published REPRODUCTION

In vitro exposure to the organochlorine p,p'-DDE affects functional human sperm parameters

Tavares, Renata S.; Amaral, Sandra; Paiva, Carla; Baptista, Marta; Ramalho-Santos, João, 2015. Chemosphere. 443 - 446. 120. 2015. . 10.1016/j.chemosphere.2014.08.075 . published Chemosphere

Spermicidal and Microbicidal Compounds: In Search of an Efficient Multipurpose Strategy

Baptista, M.; Tavares, R.; Ramalho-Santos, J., 2014. Current Medicinal Chemistry. 3693 - 3700. 32. 21. 2014. . 10.2174/0929867321666140826115929 . published Current Medicinal Chemistry

Concentration-dependent Sildenafil citrate (Viagra) effects on ROS production, energy status, and human sperm function

Sousa, M.I.; Amaral, S.; Tavares, R.S.; Paiva, C.; Ramalho-Santos, J., 2014. Systems Biology in Reproductive Medicine. 72 - 79. 2. 60. 2014. . 10.3109/19396368.2013.867380 . Systems Biology in Reproductive Medicine

p,p'-DDE activates CatSper and compromises human sperm function at environmentally relevant concentrations.

Tavares, R.S.; Mansell, S.; Barratt, C.L.; Wilson, S.M.; Publicover, S.J.; Ramalho-Santos, J., 2013. Human reproduction (Oxford, England). 3167 - 3177. 12. 28. 2013. . published Human reproduction (Oxford, England)

Evaluation of human sperm chromatin status after selection using a modified Diff-Quik stain indicates embryo quality and pregnancy outcomes following in vitro fertilization

Tavares, R.S.; Silva, A.F.; Lourenço, B.; Almeida-Santos, T.; Sousa, A.P.; Ramalho-Santos, J., 2013. Andrology. 830 - 837. 6. 1. 2013. . 10.1111/j.2047-2927.2013.00127.x . published Andrology

Acute effects of TCDD administration: special emphasis on testicular and sperm mitochondrial function. *Co-first authors

Tavares, Renata S.; Mota, Paula C.; Cordeiro, Marília; Pereira, Susana P.; Publicover, Stephen J.; Oliveira, Paulo J.; Ramalho-Santos, João, 2012. Asian Pacific Journal of Reproduction. 269 - 276. 4. 1. 2012. . 10.1016/s2305-0500(13)60091-3 . published Asian Pacific Journal of Reproduction

Not All Sperm Are Equal: Functional Mitochondria Characterize a Subpopulation of Human Sperm with Better Fertilization Potential

Sousa, Ana Paula; Amaral, Alexandra; Baptista, Marta; Tavares, Renata; Caballero Campo, Pedro; Caballero Peregrín, Pedro; Freitas, Albertina; et al, 2011. PLoS ONE. 3. 6. 2011. . 10.1371/journal.pone.0018112 . published PLoS ONE

Parabens in male infertility-Is there a mitochondrial connection?

Tavares, R.S.; Martins, F.C.; Oliveira, P.J.; Ramalho-Santos, J.; Peixoto, F.P., 2009. Reproductive Toxicology. 1 - 7. 1. 27. 2009. . 10.1016/j.reprotox.2008.10.002 . published Reproductive Toxicology

Dual use of Diff-Quik-like stains for the simultaneous evaluation of human sperm morphology and chromatin status.

Tavares, R.S.; Sousa, A.P.M.; Velez De La Calle, J.F.; Figueiredo, H.; Almeida, V.; Almeida-Santos, T.; Ramalho-Santos, J., 2009. Human Reproduction. 28 - 36. 1. 24. 2009. . 10.1093/humrep/den365 . published Human Reproduction



Best Communication - 9º Annual meeting of the Portuguese Society for Contraception

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