Overview

Biologist, PhD in Cell Biology (University of Coimbra, 2009). After being granted with 2 post-doc fellowships to study several aspects of male (in)fertility, she secured her first funding in 2013 and then recently in 2017 to further study this topic (~300K€), gaining expertise in sperm function, bioenergetics and spermatogenesis. She is a visiting scientist at the German Centre of Reproductive Medicine and Andrology. During her career she has supervised several MSc and PhD students. She has 32 publications, [h-index14-google scholar] and has presented her work in several meetings, having also participated in the organization of tree of them. In order to acquire the skills to boost her scientific knowledge, Sandra has participated in several advanced courses as the Laboratory Animal science or the IneoStart. Sandra is also actively involved in several outreach activities.

Fertilização : o que separa o processo natural do assistido

Amaral, Sandra, Revista/Boletim da Associação Portuguesa de Professores de biologia e geologia. 16. Coimbra, Portugal. 01-05-2023.

Photo of rat testis: "the blue sunflower": scientific photos exhibition at Exploratorio de coimbra

Exploratório Centro Ciência viva de Coimbra . 2023.

Metabolic characterization of human sperm cells using the Seahorse metabolic flux analyzer

Freitas-Martins, Artur; Cristo, Maria I.; Sousa, Maria Inês; Ramalho-Santos, João; Amaral, Sandra, Andrology . 2023. DOI:10.1111/andr.13486 . published Andrology

Why some couples can not have children

Amaral, Sandra; Escada-Rebelo, S.; Cristo, Maria I.; Ramalho-Santos, João; Varela Amaral, Sara; Silva, Andreia, Frontiers for young minds. 1107336. 11. 2023. doi: 10.3389/frym.2023.1107336 . published Frontiers for young minds

Prevalence and impact of antisperm antibodies in semen quality and male reproductive health aspects: a 10-year retrospective study

Silva, Andreia; Amaral, Sandra; Ramalho-Santos, João; Schlatt, S.; Schubert, Maria; Kliesch, Sabine, Fertility and Sterility. 2023. submitted Fertility and Sterility

New insights on sperm function in male infertility of unknown origin: a multimodal approach

Pacheco, Rita; Cristo, Maria I., Biomolecules . 10. 13. 2023. https://doi.org/10.3390/biom13101462 . Biomolecules 2023, 13(10), 1462; https://doi.org/10.3390/biom13101462 . published Biomolecules

Green Labs @CIBB “Collection Points” – Reuse and Recycling

Cândida, Mendes et al, 1st Green Labs Portugal Symposium: Promoting Sustainability in Research. 22-09-2023.

Rúbrica "Vamos desvendar o que a ciência nos pode ensinar" em colaboração com a Associação Portuguesa de Fertilidade

Amaral, Sandra, 23-08-2023. https://www.instagram.com/p/C0jNmS2qWFX/?img_index=1 https://www.instagram.com/p/CzMaQ7br60f/?img_index=1 https://www.instagram.com/p/CwS9-S7I81d/?img_index=1 .

GreenLabsCiBB One path for sustainable research

Santos B et al, 1st Green Labs Portugal Symposium: Promoting Sustainability in Research. 22-09-2023.

Proteomic approach to the characterization of unknown origin male infertility

Cristo, Maria I.; Pacheco, Rita; Anjo, Sandra I.; Silva, Andreia F; Sousa A.P.; Almeida-Santos, Teresa: AT Santos; Ramalho-Santos, João; Amaral, Sandra, 08-06-2022.

PROTEOMIC APPROACH TO THE CHARACTERIZATION OF UNKNOWN ORIGIN MALE INFERTILITY

Pacheco, Rita; Cristo, Maria I.; Anjo, Sandra I.; Silva, Andreia F; Sousa A.P.; Almeida-Santos, Teresa: AT Santos (3F10-47C8-F00; Ramalho-Santos, João; Amaral, Sandra, 56th ESCI 2022 Annual Scientific Meeting. 06-2022.

Functional sperm characterization in patients with infertility of unknown origin

Cristo, Maria I.; Silva, Andreia; Tavares, Renata S.; Ana Paula Sousa; Almeida-Santos, Teresa: AT Santos; Ramalho-Santos, João; Amaral, Sandra, 21St European Testis Workshop (Barcelona, Spain). 05-2021.

Mitochondrial Functional Assessment in Mammalian Gametes Using Fluorescent Probes

Tavares, Renata S.; Escada-Rebelo, Sara; Soares, Maria M.; Silva, Andreia F.; Almeida-Santos, Teresa; Amaral, Sandra; Sousa, Ana Paula; Ramalho-Santos, João, Methods in Molecular Biology. Palmeira, Carlos; Rolo, Anabela. Springer US. Coimbra, Portugal. 2021.

The impact of antisperm antibodies on sperm functionality

Silva, Andreia F; Cristo, Maria I.; Ana Paula Sousa; Almeida-Santos, Teresa: AT Santos; Schlatt, S; Ramalho-Santos, João; Amaral, Sandra, 21St European Testis Workshop (Barcelona, Spain). 05-2021.

Health in Knowledge (Saúde no Saber) podcast (https://www.facebook.com/CNC.UC/videos/sa%C3%BAde-no-saber-o-podcast-epis%C3%B3dio-1/1851039961739914/?__so__=permalink&__rv__=related_videos)

CNC. 01-01-2021.

The impact of antisperm antibodies on human male reproductive function: an update

Silva, Andreia Filipa; Ramalho-Santos, João; Amaral, Sandra, Reproduction. R55 - R71. 4. 162. 2021. http://dx.doi.org/10.1530/rep-21-0123 . 10.1530/rep-21-0123 . published Reproduction

MITOCHONDRIA-TARGETED COMPOUNDS TO ASSESS AND IMPROVE HUMAN SPERM FUNCTION

Escada-Rebelo, Sara; Cristo, Maria Inês; Ramalho-Santos, Joao; Amaral, Sandra, Antioxidants & Redox Signaling. 2021. http://dx.doi.org/10.1089/ars.2021.0238 . 10.1089/ars.2021.0238 . published Antioxidants & Redox Signaling

Topological distribution of functional-biochemical features of spermatozoa by Raman Microspectroscopy

Zieger, V; da Costa, Raul; Amaral, Sandra; Schlatt, S, 2020.

The functionality of the sperm cell in the presence of antisperm antibodies

Silva, Andreia; Cristo, MI; Ana Paula Sousa; Almeida-Santos, Teresa: AT Santos; Schlatt, S; Ramalho-Santos, João; Amaral, Sandra, 2020.

The functionality of the sperm cell in the presence of antisperm antibodies

Silva, Andreia; Ana Paula Sousa; Almeida-Santos, Teresa: AT Santos; Schlatt, S; Ramalho-Santos, João; Amaral, Sandra, 12th International/11th European/ 32nd German Congress of Andrology (5-9 December, 2020, Münster; Germany) . 05-12-2020.

Is sperm functionality affected in patients with male infertility of unknown origin?

Cristo, Maria I; Silva, Andreia; Tavares, Renata S.; Ana Paula Sousa; Moura-Ramos, Mariana; Almeida-Santos, Teresa: AT Santos; Ramalho-Santos, João; Amaral, Sandra, SSR Meeting (Ontario, Canada). 09-07-2020.

Sperm quality in patients with infertility of unknown origin

Cristo, Maria I; Silva, Andreia; Tavares, Renata S.; Ana Paula Sousa; Almeida-Santos, Teresa: AT Santos; Ramalho-Santos, João; Amaral, Sandra, CIBB (Center for Inovative Biomedicine and Biotechnology) meeting (Coimbra, Portugal). 12-2019.

Male infertiltiy: and when we don't know why? (Infertilidade masculina: e quando não sabemos porque?) https://www.youtube.com/watch?v=RYC7MyZ1a1g&feature=youtu.be

2019.

How does the presence of antisperm antibodies influence sperm functionality?

Silva, Andreia; Cristo, Maria I; Ana Paula Sousa; Almeida-Santos, Teresa: AT Santos; Schlatt, S; Ramalho-Santos, João; Amaral, Sandra, CIBB (center for Inovative Biomedicine and Biotechnology) Meeting (Coimbra, Portugal). 12-2019.

Can Antidiabetic Drugs Improve Male Reproductive (Dys)Function Associated with Diabetes?

Tavares, Renata S.; Escada-Rebelo, Sara; Sousa, Maria Inês; Silva, Andreia; Ramalho-Santos, João; Amaral, Sandra, Current Medicinal Chemistry. 4191 - 4222. 22. 26. 2019. http://dx.doi.org/10.2174/0929867325666181101111404 . 10.2174/0929867325666181101111404 . published Current Medicinal Chemistry

How does the presence of antisperm antibodies influence sperm functionality?

Silva, Andreia; Ana Paula Sousa; Almeida-Santos, Teresa: AT Santos; Schlatt, S; Ramalho-Santos, João; Amaral, Sandra, 6th International Workshop on Molecular Andrology (Giessen, Germany). 09-2019.

Caracterização da função espermática em pacientes com infertilidade idiopática.

Fonseca, Ema; Silva, Andreia; Ana Paula Sousa; Almeida-Santos, Teresa: AT Santos; Ramalho-Santos, João; Amaral, Sandra, 7º Congresso Português de Medicina da Reprodução (Oporto, Portugal). 05-2019.

Characterization of sperm function in patients with idiopathic infertility

Fonseca, Ema; Silva, Andreia; Ana Paula Sousa; Almeida-Santos, Teresa: AT Santos; Ramalho-Santos, João; Amaral, Sandra, 29-04-2019.

Characterization of sperm function in patients with idiopathic infertility.

Fonseca, Ema; Silva, Andreia; Ana Paula Sousa; Almeida-Santos, Teresa: AT Santos; Ramalho-Santos, João; Amaral, Sandra, 53rd Annual Scientific Meeting of the European Society for Clinical Investigation (Coimbra, Portugal). 05-2019.

II. TIPOS DE CÉLULAS ESTAMINAIS. II.7– GÓNADAS

Ramalho-Santos, João; Almeida-Santos, Teresa; Sousa, Ana P; Tavares, Renata S.; Mota, Paula C.; Amaral, Sandra, Sociedade portuguesa de Células Estaminais e Terapia Celular. 2018. accepted

Mammalian Sperm Mitochondrial Function as Affected by Environmental Toxicants, Substances of Abuse, and Other Chemical Compounds (chapter 11)

Amaral, Sandra; Tavares, Renata S.; Escada-Rebelo, Sara; Silva, Andreia; Ramalho-Santos, João, Mitochondrial Dysfunction Caused by Drugs and Environmental Toxicants. Yvonne Will. John Wiley & Sons, Inc.. 2018. published

Raman microspectroscopy analysis of different sperm regions: a species comparison

Amaral, Sandra; Da Costa, Raul; Wübelling, Frank; Redmann, Klaus; Schlatt, S, 20th European testis Workshop (Óbidos, Portugal). 05-2018.

Spectral features of nuclear DNA in human sperm assessed by Raman Microspectroscopy: Effects of UV-irradiation and hydration

da Costa, Raul; Amaral, Sandra; Redmann, Klaus; Kliesch, S; Schlatt, S., PloS one. e0207786 - e0207786. 11. 13. 2018. http://www.scopus.com/inward/record.url?eid=2-s2.0-85056802974&partnerID=MN8TOARS . 10.1371/journal.pone.0207786 . published PloS one

Can we induce spermatogenesis in the domestic cat using an in vitro tissue culture approach?

Silva, Andreia; Escada-Rebelo, S.; Amaral, Sandra; Tavares, Renata S.; Schlatt, S; Ramalho-Santos, João; Mota, Paula C, PLoS ONE. 2. 13. 2018. http://www.scopus.com/inward/record.url?eid=2-s2.0-85041519878&partnerID=MN8TOARS . 10.1371/journal.pone.0191912 . published PLoS ONE

Participation in the photo exhibition and contest "TEStART" at the 20th European Testis Workshop

Amaral, Sandra, Universidade de Coimbra Centro de Neurociências e Biologia Celular . 2018.

Raman micro-spectroscopy analysis of different sperm regions: a species comparison

Amaral, Sandra; Da Costa, Raul; Wübbeling, Frank; Redmann, Klaus; Schlatt, S, MHR: Basic science of reproductive medicine. 185 - 202. 4. 24. 2018. http://dx.doi.org/10.1093/molehr/gax071 . 10.1093/molehr/gax071 . published MHR: Basic science of reproductive medicine

Antidiabetic therapies and male reproductive function: where do we stand? (top dowloaded paper in 2018 on Reproduction Journal)

Tavares, Renata S.; Escada-Rebelo, Sara; Silva, Andreia; Sousa, Maria Inês; Ramalho-Santos, João; Amaral, Sandra, Reproduction (Cambridge, England). R13 - R37. 1. 155. 2017. http://europepmc.org/abstract/med/28993453 . 10.1530/rep-17-0390 . published Reproduction (Cambridge, England)

High glucose levels affect spermatogenesis: an in vitro approach.

Tavares, Renata S.; Portela, J; Sousa, Maria Inês; Mota, Paula C; Ramalho-Santos, João; Amaral, Sandra, Reproduction, Fertility and Development. 1369 - 1378. 7. 29. 2017. http://europepmc.org/abstract/med/27264729 . 10.1071/rd15475 . published Reproduction, Fertility and Development

Does high glucose impair spermatogenesis and sperm function in vitro?

Portela, Joana; Tavares, Renata S.; Mota, Paula C; Sousa, Maria Inês; Ramalho-Santos, João; Amaral, Sandra, Reproduction Health Summit (London, UK). 04-2016.

Mitochondrial Functionality and Chemical Compound Action on Sperm Function

Amaral, Sandra; Tavares, Renata S.; Baptista, Marta; Sousa, Maria Inês; Silva, Andreia; Escada-Rebelo, Sara; Paiva, Carla; Ramalho-Santos, João, Current Medicinal Chemistry. 3575 - 3606. 31. 23. 2016. http://dx.doi.org/10.2174/0929867323666160425113518 . 10.2174/0929867323666160425113518 . published Current Medicinal Chemistry

Spermatogonial stem cell organization in felid testis as revealed by Dolichos biflorus lectin.

Escada-Rebelo, Sara; Silva, Andreia; Amaral, Sandra; Tavares, Renata S.; Paiva, Carla; Schlatt, S; Ramalho-Santos, João; Mota, Paula C, Andrology. 1159 - 1168. 6. 4. 2016. http://europepmc.org/abstract/med/27317258 . 10.1111/andr.12223 . published Andrology

In vitro exposure to the organochlorine p,p'-DDE affects functional human sperm parameters

Tavares, Renata S.; Amaral, Sandra; Paiva, Carla; Baptista, Marta; Ramalho-Santos, João, Chemosphere. 443 - 446. 120. 2015. http://dx.doi.org/10.1016/j.chemosphere.2014.08.075 . 10.1016/j.chemosphere.2014.08.075 . published Chemosphere

Diabetes mellitus, spermatogenesis progression and sperm function: Does a spoonful of sugar compromise male fertility?

Tavares, Renata S.; Portela, Joana; Sousa, Maria Inês; Mota, Paula C; Ramalho-Santos, João; Amaral, Sandra, 06-2015.

Diabetes mellitus, spermatogenesis progression and sperm function: Does a spoonful of sugar compromise male fertility?

Tavares, Renata S.; Portela, Joana; Sousa, Maria Inês; Mota, Paula C; Ramalho-Santos, João; Amaral, Sandra, 31st Annual Meeting of the European Society for Human Reproduction and Embriology (ESHRE) (Lisbon, Portugal). 06-2015.

High glucose concentrations per se do not adversely affect human sperm function in vitro

Portela, Joana; Tavares, Renata S.; Mota, Paula C; Ramalho-Santos, João; Amaral, Sandra, REPRODUCTION. 77 - 84. 1. 150. 2015. http://dx.doi.org/10.1530/rep-15-0100 . 10.1530/rep-15-0100 . published REPRODUCTION

Publicity of the results of the scientific work "Diabetes and male fertility" on more than 55 national daily journals (http://www.cnbc.pt/outreach/outreach00.asp?pagina=11#divNews)

05-2015.

Participation in the Art exhibition "A transmissão da vida: beleza de um universo desconhecido"

Amaral, Sandra, Centro Hospitalar e Universitário de Coimbra EPE . 2014.

Concentration-dependent Sildenafil citrate (Viagra) effects on ROS production, energy status, and human sperm function

Sousa, Maria Inês; Amaral, Sandra; Tavares, Renata S.; Paiva, Carla; Ramalho-Santos, João, Systems Biology in Reproductive Medicine. 72 - 79. 2. 60. 2014. http://www.scopus.com/inward/record.url?eid=2-s2.0-84901672805&partnerID=MN8TOARS . 10.3109/19396368.2013.867380 . published Systems Biology in Reproductive Medicine

Does hyperglycaemia affect human spermatozoa in vitro?

Tavares, Renata S.; Portela, Joana; Ramalho-Santos, João; Amaral, Sandra, 18th European Testis Workshop (Elsinore, Denmark). 05-2014.

DDE affects human sperm function at environmentally relevant concentrations

Tavares, Renata S.; Baptista, Marta; Amaral, Sandra; Paiva, Carla; Publicover, SJ; Ramalho-Santos, João, 1as Jornadas científicas de medicina da reprodução do Centro Hospitalar de Lisboa Central (Lisbon, Portugal). 11-2014.

Does high glucose impair spermatogenesis and sperm function in vitro?

Tavares, Renata S.; Portela, Joana; Mota, Paula C; Sousa, Maria I; Ramalho-Santos, João; Amaral, Sandra, 3rd World Congress on reproduction, oxidative stress and antioxidants (Paris, France). 05-2014.

How do high glucose levels influence the spermatogenic process?

Portela, Joana; Tavares, Renata S.; Sousa, Maria Inês; Mota, Paula C; Ramalho-Santos, João; Amaral, Sandra, 18th European Testis Workshop" (Elsinore, Denmark). 05-2014.

Free Radical Biology and Reproductive Health in Diabetes

Amaral, Sandra; Ramalho-Santos, João, Systems Biology of Free Radicals and Antioxidants. Springer Berlin Heidelberg. 2014. published

Does high glucose impair spermatogenesis and sperm function in vitro?

Portela, Joana; Tavares, Renata S.; Mota, Paula C; Sousa, Maria Inês; Ramalho-Santos, João; Amaral, Sandra, 1as Jornadas científicas de Medicina da Reprodução do Centro Hospitalar de Lisboa Central (Lisbon, Portugal). 11-2014.

Mitochondria and mammalian reproduction

Ramalho-Santos, João; Amaral, Sandra, Molecular and Cellular Endocrinology. 74 - 84. 1-2. 379. 2013. http://www.scopus.com/inward/record.url?eid=2-s2.0-84884535027&partnerID=MN8TOARS . 10.1016/j.mce.2013.06.005 . published Molecular and Cellular Endocrinology

UVB irradiation as a tool to assess ROS-induced damage in human spermatozoa

Amaral, Sandra; Redmann, Klaus; Sanchez, V.; Mallidis, Con; Ramalho-Santos, João; Schlatt, S, Andrology. 707 - 714. 5. 1. 2013. http://www.scopus.com/inward/record.url?eid=2-s2.0-84883044268&partnerID=MN8TOARS . 10.1111/j.2047-2927.2013.00098.x . published Andrology

Aging and male reproductive function: a mitochondrial perspective.

Amaral, Sandra; Ramalho-Santos, João, 181 - 187. S5. 2013. http://europepmc.org/abstract/med/23277044 . 10.2741/s365 . published

Concentration-dependent Sildenafil citrate (Viagra®) effects on ROS production, energy status and human sperm function

Sousa, Maria Inês; Amaral, Sandra; Tavares, Renata S.; Paiva, Carla; Ramalho-Santos, João, 6th Meeting of the International Network of Young Researchers in Male Fertility (INYRMF) (Barcelona, Spain). 05-2013.

Environmental p,p'-DDE promotes intracellular Ca2+ rise in human sperm: a novel non-genomic mechanism that compromises male fertility;

Tavares, Renata S.; Baptista, Marta; Paiva, Carla; Amaral, Sandra; Publicover, SJ; Ramalho-Santos, João, 6th Meeting of the International Network of Young Researchers in Male Fertility (INYRMF) (Barcelona, Spain). 05-2013.

Environmental DDE modulates Human Sperm Function

Tavares, Renata S.; Baptista, Marta; Paiva, Carla; Amaral, Sandra; Publicover, SJ; Ramalho-Santos, João, 17th European Testis Workshop (Stockholm, Sweden). 04-2012.

DDE affects Human Sperm Function at Environmentally relevant Concentrations

Tavares, Renata S.; Baptista, Marta; Amaral, Sandra; Paiva, Carla; Publicover, SJ; Ramalho-Santos, João, ESHRE annual metting (Istambul, Turkey). 07-2012.

Aging, Mitochondria and Male Reproductive Function

Amaral, Sandra; Ramalho-Santos, João, Current Aging Sciencee. 165 - 173. 3. 2. 2009. http://dx.doi.org/10.2174/1874609810902030165 . 10.2174/1874609810902030165 . published Current Aging Sciencee

Diabetes, Age and Male Reproductive Function

Amaral, Sandra Catarina Gomes, phd. Universidade de Coimbra . 2009. http://hdl.handle.net/10316/10226 .

Mitochondrial functionality in reproduction: from gonads and gametes to embryos and embryonic stem cells

Ramalho-Santos, João; Varum, Sandra; Amaral, Sandra; Mota, Paula C; Ana Paula Sousa; Amaral, Alexandra, Human Reproduction Update. 553 - 572. 5. 15. 2009. http://dx.doi.org/10.1093/humupd/dmp016 . 10.1093/humupd/dmp016 . published Human Reproduction Update

Mitochondrial bioenergetics of testicular cells from the domestic cat (Felis catus)- A model for endangered species

Mota, Paula C; Amaral, Sandra; Martins, Luís; de Lourdes Pereira, Maria; Oliveira, Paulo; Ramalho-Santos, João, Reproductive Toxicology. 111 - 116. 2. 27. 2009. http://dx.doi.org/10.1016/j.reprotox.2009.01.008 . 10.1016/j.reprotox.2009.01.008 . published Reproductive Toxicology

Testicular mitochondrial alterations in untreated streptozotocin-induced diabetic rats

Amaral, Sandra; Mota, Paula C; Lacerda, Beatriz; Alves, Marco; Pereira, Maria de Lourdes; Oliveira, Paulo; Ramalho-Santos, João, Mitochondrion. 41 - 50. 1. 9. 2009. http://dx.doi.org/10.1016/j.mito.2008.11.005 . 10.1016/j.mito.2008.11.005 . published Mitochondrion

Diabetes and the Impairment of Reproductive Function: Possible Role of Mitochondria and Reactive Oxygen Species

Ramalho-Santos, João; Amaral, Sandra; Oliveira, Paulo, Current Diabetes Reviews. 46 - 54. 1. 4. 2008. http://dx.doi.org/10.2174/157339908783502398 . 10.2174/157339908783502398 . published Current Diabetes Reviews

Testicular aging involves mitochondrial dysfunction as well as an increase in UCP2 levels and proton leak

Amaral, Sandra; Mota, Paula C; Rodrigues, Ana Sofia; Martins, Luís; Oliveira, Paulo; Ramalho-Santos, João, FEBS Letters. 4191 - 4196. 30. 582. 2008. http://dx.doi.org/10.1016/j.febslet.2008.11.020 . 10.1016/j.febslet.2008.11.020 . published FEBS Letters

Characterization of mitochondrial bioenergetics of cat testicular cells: variations with age and other functions

Mota, Paula C; Martins, Luís; Amaral, Sandra; Oliveira, Paulo; Ramalho-Santos, João, 15th European testis workshop" ( Naantali, Finland). 05-2008.

Mitochondrial testicular function: effects of age

Amaral, Sandra; Mota, Paula C; Lacerda, Beatriz; Oliveira, Paulo; Ramalho-Santos, João, 15th European testis workshop (Naantali, Finland). 05-2008.

Characterization of the mitochondrial membrane potential in domestic cat testicular cells: possible implications for germ cell function

Mota, Paula C; Martins, Luís; Amaral, Sandra; Oliveira, Paulo; Ramalho-Santos, João, 40th Annual Meeting of the Society for the Study of Reproduction” (San Antonio, Texas, USA). 07-2007.

Mitochondrial testicular function: effects of age and diabetes

Amaral, Sandra; Martins, Luís; Mota, Paula C; Oliveira, Paulo; Ramalho-Santos, João, 01-07-2007.

Mitochondrial testicular function: effects of age and diabetes

Amaral, Sandra; Martins, Luís; Mota, Paula C; Oliveira, Paulo; Ramalho-Santos, João, 40th Annual Meeting of the Society for the Study of Reproduction (Santo António, Texas, USA). 07-2007.

Probing the Structure and Function of Mammalian Sperm using Optical and Fluorescence Microscopy

Ramalho-Santos, João; Amaral, Alexandra; Ana Paula Sousa; Rodrigues, AS; Mota, Paula C; Amaral, Sandra; Gamboa, S, Modern Research and Educational Topics in Microscopy. Méndez-Vilar A; Diaz J. 2007. published

Mitochondrial testicular function: effects of age and Diabetes

Amaral, Sandra; Martins, Luís; Mota, Paula C; Oliveira, Paulo; Ramalho-Santos, João, MiP (mitochondrial Physiology) Summer Scholl (Schrocken, Vorarlberg, Austria). 07-2007.

Characterization of the mitochondrial membrane potential in domestic cat testicular cells: possible implications for germ cell function

Mota, Paula C; Martins, Luís; Amaral, Sandra; Oliveira, Paulo; Ramalho-Santos, João, 01-07-2007.

Effects of hyperglycemia on sperm and testicular cells of Goto-kakizaki and Streptozotocin-treated rats

Amaral, Sandra; Moreno, A; Santos, Maria S; Seiça, Raquel; Ramalho-Santos, João, 39th Annual Meeting of the Society for the Study of Reproduction (Omaha, Nebraska, USA). 07-2006.

Diabetes induces spermatogenesis and epididymal alterations in Goto- Kakizaki and streptozotocin-treated rat models for diabetes: a histological approach

Amaral, Sandra; Oliveira, Helena; Pereira, Maria de Lourdes; Ramalho-Santos, João, XV Congresso Nacional de Bioquímica (Aveiro, Portugal). 12-2006.

Effects of hyperglycemia on sperm and testicular cells of Goto-Kakizaki and streptozotocin-treated rat models for diabetes

Amaral, Sandra; Moreno, António J.; Santos, Maria Sancha; Seiça, Raquel; Ramalho-Santos, João, Theriogenology. 2056 - 2067. 9. 66. 2006. http://dx.doi.org/10.1016/j.theriogenology.2006.06.006 . 10.1016/j.theriogenology.2006.06.006 . published Theriogenology

Effects of Hyperglycemia on Sperm and testicular cells of Goto- Kakizaki and Streptozotocin-treated rats

Amaral, Sandra; Oliveira, Pedro; Ramalho-Santos, João, XIV Congresso Nacional de Bioquímica (Vilamoura, Portugal). 12-2004.

Diabetes induces metabolic adaptations in rat testis: Analysis of enzymatic activities and ATP levels

Amaral, Sandra; Oliveira, Pedro; Ramalho-Santos, João, 3rd Portuguese-Spanish Biophysics Congress (Lisbon, Portugal). 11-2004.

Co-author of a cartoon published in the Portuguese daily newspaper "Público", regarding the impact of Diabetes in several organ systems: "Viagem na Diabetes". https://www.publico.pt/2017/11/14/fotogaleria/viagens-na-diabetes-em-bd-378982 (November 14th, 2017)

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Co-author of a cartoon published in the Portuguese daily newspaper "Público", regarding the importance of sleep for health: "Viagens sem insónias" https://www.publico.pt/2018/03/16/fotogaleria/viagens-sem-insonias-381315 (March 16th, 2018)

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Challenge "Draw my science" at the CIBB meeting 2023

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All projects

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Information of exclusive responsibility of the researcher 17-12-2023 , from platform CIÊNCIAVITAE.

2021 - 2025

SR&TD Project - SCHL 394/16-1 " Biochemical and physiological characterization of human spermatozoa using novel optical technologies - A new understanding of sperm functional competence" (400k|3yrs| DGF)

SCHL 394/16-1

Researcher

Universitätsklinikum Münster Centrum für Reproduktionsmedizin und Andrologie

Funders: Deutsche Forschungsgemeinschaft

2018 - 2022

SR&TD Project - PTDC/MEC-AND/28599/2017 |(POCI-01-0145-FEDER-028599) (236.679,81 eur, 3 Years, FCT): "Searching for novel biomarkers in unknown origin (UOMI) male infertility"

PTDC/MEC-AND/28599/2017

Principal investigator

Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: Fundação para a Ciência e a Tecnologia

2016/01 - 2017/12

Cooperation Project- AI A06/16 (4000 eur, 2 Years, CRUP_DAAD) : "Pesquisa de novos biomarcadores para a infertilidade masculina inexplicada"

AI06/ 16

Principal investigator

Universidade de Coimbra Centro de Neurociências e Biologia Celular; Universitätsklinikum Münster Centrum für Reproduktionsmedizin und Andrologie

Funders: Deutscher Akademischer Austauschdienst; CRUP (Conselho de Reitores das Universidades Portuguesas-Portuguese Council of University Rectors)

2013 - 2015

Cooperation project: Bilateral exchanging program between FCT and DAAD. "Fertility preservation in endangered felids"

n/a

Researcher

Universitätsklinikum Münster Centrum für Reproduktionsmedizin und Andrologie

Funders: Deutscher Akademischer Austauschdienst; Fundação para a Ciencia e Tecnologia

2013/01 - 2014/12

Exploratory project - EXPL/BEX-BCM/0224/2012 (48.132 eur, 1.5 year, FCT):"Novel insights into the reproductive dysfunction in diabetes: 3D dimensional analysis of spermatogenesis and analysis of mitochondria status through Confocal Raman Microscopy"

EXPL/BEX-BCM/0224/2012

Principal investigator

Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: Fundação para a Ciencia e Tecnologia

2012 - 2015

PTDC/EBB-EBI/120634/2010 "Metabolic modulation as a tool to create and propagate pluripotent stem cell lines"

PTDC/EBB-EBI/120634/2010

Other

Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: Fundação para a Ciência e a Tecnologia

2012 - 2015

PTDC/QUI-BIQ/120652/2010 "Role of the pyruvate dehydrogenase Kinase metabolic swith in pluripotency insights into cancer and stem cell biology"

PTDC/QUI-BIQ/120652/2010

Other

Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: Fundação para a Ciência e a Tecnologia

2012 - 2015

PTDC/CVT/119477/2010:"New strategies to recover fertility and genetic variability of endangered felids: development of xenografting and spermatogonial stem cell transplantation in domestic cat as model for endangered felids"

PTDC/CVT/119477/2010

Researcher

Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: Fundação para a Ciência e a Tecnologia

2010 - 2013

PTDC/EBB­-EBI/101114/2008 " Metabolism as a modulator of stem cell pluripotency and differentiation"

PTDC/EBB­-EBI/101114/2008

Other

Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: Fundação para a Ciência e a Tecnologia

2006 - 2008

III/BIO/50/2005 "What makes a good spermatozoon? a trans-specific perspective" University of coimbra, Instituto de investigação interdisciplinar

III/BIO/50/2005

Other

Universidade de Coimbra

Funders: Universidade de Coimbra

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