Publications
Information about journal articles, updated at 19-03-2023, from platform CIÊNCIAVITAE.
Editorial: Global excellence in gene and cell therapy: Europe
Mendonça, Liliana; Boltze, Johannes; Nóbrega, Clévio, Frontiers in Medicine. 10. 2023. http://dx.doi.org/10.3389/fmed.2023.1154360 . 10.3389/fmed.2023.1154360 . published Frontiers in Medicine
Editorial: Advanced (gene and cell) therapies for central nervous system applications
Mendonça, Liliana; Webster, Christopher; Boltze, Johannes; Nóbrega, Clévio, Frontiers in Molecular Neuroscience. 16. 2023. http://dx.doi.org/10.3389/fnmol.2023.1140949 . 10.3389/fnmol.2023.1140949 . published Frontiers in Molecular Neuroscience
The stress granule protein G3BP1 alleviates spinocerebellar ataxia-associated deficits
Koppenol, Rebekah; Conceição, André; Afonso, Inês T; Afonso-Reis, Ricardo; Costa, Rafael G; Tomé, Sandra; Teixeira, Diogo; et al, Brain. 2022. http://dx.doi.org/10.1093/brain/awac473 . 10.1093/brain/awac473 . published Brain
Establishment and characterization of human pluripotent stem cells-derived brain organoids to model cerebellar diseases
Brás, João; Henriques, Daniel; Moreira, Ricardo; Santana, Magda M.; Silva-Pedrosa, Rita; Adão, Diana; Braz, Sandra; et al, Scientific Reports. 1. 12. 2022. http://dx.doi.org/10.1038/s41598-022-16369-y . 10.1038/s41598-022-16369-y . Scientific Reports
Extracellular Vesicles Physiological Role and the Particular Case of Disease-Spreading Mechanisms in Polyglutamine Diseases
Moreira, Ricardo; Mendonça, Liliana S.; Pereira de Almeida, Luís, International Journal of Molecular Sciences. 22. 22. 2021. http://dx.doi.org/10.3390/ijms222212288 . 10.3390/ijms222212288 . International Journal of Molecular Sciences
Lysosomal Storage Disease-Associated Neuropathy: Targeting Stable Nucleic Acid Lipid Particle (SNALP)-Formulated siRNAs to the Brain as a Therapeutic Approach
Coutinho, Maria Francisca; Santos, Juliana Inês; S. Mendonça, Liliana; Matos, Liliana; Prata, Maria João; S. Jurado, Amália; Pedroso de Lima, Maria C.; Alves, Sandra, International Journal of Molecular Sciences. 16. 21. 2020. http://dx.doi.org/10.3390/ijms21165732 . 10.3390/ijms21165732 . published International Journal of Molecular Sciences
RNA Interference Therapy for Machado-Joseph Disease: Long-Term Safety Profile of Lentiviral Vectors Encoding Short Hairpin RNAs Targeting Mutant Ataxin-3
Nóbrega, Clévio; Codêsso, José Miguel; Mendonça, Liliana; Pereira de Almeida, Luís, Human Gene Therapy. 841 - 854. 7. 30. 2019. http://dx.doi.org/10.1089/hum.2018.157 . 10.1089/hum.2018.157 . published Human Gene Therapy
Ibuprofen enhances synaptic function and neural progenitors proliferation markers and improves neuropathology and motor coordination in Machado–Joseph disease models
Mendonça, Liliana S; Nóbrega, Clévio; Tavino, Silvia; Brinkhaus, Maximilian; Matos, Carlos; Tomé, Sandra; Moreira, Ricardo; et al, Human Molecular Genetics. 3691 - 3703. 22. 28. 2019. http://dx.doi.org/10.1093/hmg/ddz097 . 10.1093/hmg/ddz097 . Human Molecular Genetics
Restoring brain cholesterol turnover improves autophagy and has therapeutic potential in mouse models of spinocerebellar ataxia
Nóbrega, Clévio; Mendonça, Liliana; Marcelo, Adriana; Lamazière, Antonin; Tomé, Sandra; Despres, Gaetan; Matos, Carlos A.; et al, Acta Neuropathologica. 837 - 858. 5. 138. 2019. http://dx.doi.org/10.1007/s00401-019-02019-7 . 10.1007/s00401-019-02019-7 . published Acta Neuropathologica
Understanding how birds rebuild fat stores during migration: insights from an experimental study
Araújo, Pedro M.; Viegas, Ivan; Rocha, Afonso D.; Villegas, Auxiliadora; Jones, John G.; Mendonça, Liliana; Ramos, Jaime A.; Masero, José A.; Alves, José A., Scientific Reports. 1. 9. 2019. http://dx.doi.org/10.1038/s41598-019-46487-z . 10.1038/s41598-019-46487-z . published Scientific Reports
Cordycepin activates autophagy through AMPK phosphorylation to reduce abnormalities in Machado-Joseph disease models
Marcelo, Adriana; Brito, Filipa; Carmo-Silva, Sara; Matos, Carlos A; Alves-Cruzeiro, João; Vasconcelos-Ferreira, Ana; Koppenol, Rebekah; et al, Human Molecular Genetics. 51 - 63. 1. 28. 2018. http://dx.doi.org/10.1093/hmg/ddy328 . 10.1093/hmg/ddy328 . Human Molecular Genetics
Motor Dysfunctions and Neuropathology in Mouse Models of Spinocerebellar Ataxia Type 2: A Comprehensive Review
Alves-Cruzeiro, João M. Da Conceição; Mendonça, Liliana; Pereira de Almeida, Luís; Nóbrega, Clévio, Frontiers in Neuroscience. 10. 2016. http://dx.doi.org/10.3389/fnins.2016.00572 . 10.3389/fnins.2016.00572 . published Frontiers in Neuroscience
Safety profile of the intravenous administration of brain-targeted stable nucleic acid lipid particles
Conceição, M.; Mendonça, L.; Nóbrega, C.; Gomes, C.; Costa, P.; Hirai, H.; Moreira, J.N.; et al, Data in Brief. 700 - 705. 6. 2016. http://www.scopus.com/inward/record.url?eid=2-s2.0-84956617357&partnerID=MN8TOARS . 10.1016/j.dib.2016.01.017 . Data in Brief
Intravenous administration of brain-targeted stable nucleic acid lipid particles alleviates Machado-Joseph disease neurological phenotype
Conceição, M.; Mendonça, L.; Nóbrega, C.; Gomes, C.; Costa, P.; Hirai, H.; Moreira, J.N.; et al, Biomaterials. 124 - 137. 82. 2016. http://www.scopus.com/inward/record.url?eid=2-s2.0-84956644943&partnerID=MN8TOARS . 10.1016/j.biomaterials.2015.12.021 . published Biomaterials
Re-establishing ataxin-2 downregulates translation of mutant ataxin-3 and alleviates Machado-Joseph disease
Nóbrega, C.; Carmo-Silva, S.; Albuquerque, D.; Vasconcelos-Ferreira, A.; Vijayakumar, U.-G.; Mendonça, L.; Hirai, H.; Pereira De Almeida, L., Brain. 3537 - 3554. 12. 138. 2015. http://www.scopus.com/inward/record.url?eid=2-s2.0-84951031850&partnerID=MN8TOARS . 10.1093/brain/awv298 . published Brain
Transplantation of cerebellar neural stem cells improves motor coordination and neuropathology in Machado-Joseph disease mice
Mendonça, Liliana S.; Nóbrega, Clévio; Hirai, Hirokazu; Kaspar, Brian K.; Pereira de Almeida, Luís, Brain. 320 - 335. 2. 138. 2014. http://dx.doi.org/10.1093/brain/awu352 . 10.1093/brain/awu352 . published Brain
Tumor-targeted Chlorotoxin-coupled Nanoparticles for Nucleic Acid Delivery to Glioblastoma Cells: A Promising System for Glioblastoma Treatment
Costa, Pedro M; Cardoso, Ana L; Mendonça, Liliana S; Serani, Angelo; Custódia, Carlos; Conceição, Mariana; Simões, Sérgio; et al, Molecular Therapy - Nucleic Acids. 2. 2013. http://dx.doi.org/10.1038/mtna.2013.30 . 10.1038/mtna.2013.30 . published Molecular Therapy - Nucleic Acids
Targeted lipid-based systems for siRNA delivery
Mendonça, L.S.; Pedroso de Lima, M.C.; Simões, S., Journal of Drug Delivery Science and Technology. 65 - 73. 1. 22. 2012. http://dx.doi.org/10.1016/s1773-2247(12)50006-7 . 10.1016/s1773-2247(12)50006-7 . published Journal of Drug Delivery Science and Technology
Transferrin Receptor-Targeted Liposomes Encapsulating anti-BCR-ABLsiRNA or asODN for Chronic Myeloid Leukemia Treatment
Mendonça, Liliana S.; Firmino, Filipe; Moreira, João N.; Pedroso de Lima, Maria C.; Simões, Sérgio, Bioconjugate Chemistry. 157 - 168. 1. 21. 2010. http://dx.doi.org/10.1021/bc9004365 . 10.1021/bc9004365 . published Bioconjugate Chemistry
Co-encapsulation of anti-BCR-ABL siRNA and imatinib mesylate in transferrin receptor-targeted sterically stabilized liposomes for chronic myeloid leukemia treatment
Mendonça, Liliana S.; Moreira, João N.; de Lima, Maria C. Pedroso; Simões, Sérgio, Biotechnology and Bioengineering. 884 - 893. 5. 107. 2010. http://dx.doi.org/10.1002/bit.22858 . 10.1002/bit.22858 . published Biotechnology and Bioengineering
5 20 out of 20 Publications
All projects
Information of exclusive responsibility of the researcher 19-03-2023 , from platform CIÊNCIAVITAE.
2023/01 -
Exploring CITED2 role in glioblastoma stem cell biology
2022.09209.PTDC
Researcher
Universidade do Algarve - Campus de Gambelas
2022/01/01 -
Identification of S-sulfhydration targets in Down Syndrome: the role of gasotransmitter hydrogen sulfide (H2S) signaling in neurodevelopment
EXPL/MED-NEU/1240/2021
Researcher
Universidade do Algarve - Campus de Gambelas
Funders: Fundação para a Ciência e a Tecnologia
2018/10/13 - 2021/10/13
The role of stress granules in polyglutamine diseases: from pathogenesis to molecular therapy
PTDC/MED-NEU/29480/2017
Researcher
Universidade do Algarve Centro de Investigação em Biomedicina
Funders: Fundação para a Ciência e a Tecnologia
2018/06 - 2022/06
"The impact of induced pluripotent stem cells-derived neuroepithelial stem cells transplantation in Machado-Joseph disease"
POCI-01-0145-FEDER-030737
Principal investigator
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Funders: Fundação para a Ciência e a Tecnologia
2017 - 2019
Neuroprotective therapeutic approach for Spinocerebellar Ataxia type 2: pharmacological targeting of AMPK
Ataxia UK2017-2019
Researcher
Universidade do Algarve Centro de Investigação em Biomedicina
Funders: Ataxia UK
2016/01/01 - 2018/12/31
Imaging Gene Therapy in the Brain
P2020PTDC/BBB NAN/0932/2014
Researcher
Funders: Fundação para a Ciência e a Tecnologia
2016/05/10 - 2018/06/30
Does the transplantation of mutant ataxin-3-depleted patient-derived NSC alleviates Machado Joseph disease (MJD)?
20126 [ 2016 ]
Principal investigator
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Funders: AFM-Téléthon
2016/01/01 - 2017/12/31
The transplantation of induced pluripotent stem cells (IPSC)-derived neural stem cells (NSC) in Machado Joseph disease (MJD)
NAF2016
Principal investigator
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Funders: National Ataxia Foundation
2015/03/01 - 2019
Roles and mechanisms of synuclein and ataxin-3 spreading in Parkinson and Machado-Joseph diseases
info:eu-repo/grantAgreement/FCT/3599-PPCDT/138566/PT
Researcher
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Funders: Fundação para a Ciência e a Tecnologia
2013 - 2015
Funding of RD Units Strategic Plan - 2013/2015 - OE
CNC. IBILI UID/NEU/04539/2013
Researcher
CNC.IBILI
Funders: Fundação para a Ciência e a Tecnologia
2013/01/01 - 2014/12/31
Strategic Project - LA 1 - 2013-2014
info:eu-repo/grantAgreement/FCT/COMPETE/132990/PT
Researcher
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Funders: Fundação para a Ciência e a Tecnologia
2013/12/31 - 2014/12/31
Transplantation of neural stem cells (NSC) as a new therapeutic strategy for Machado-Joseph disease (MJD)
CPD0021001 (08)
Principal investigator
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Funders: National Ataxia Foundation
2012/01 - 2015/07
Dissecting the pathogenesis of Machado-Joseph disease in a new human disease model derived from induced pluripotent stem cells
grant.Provided by PTCRIS: 116512
Researcher
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Funders: Fundação para a Ciência e a Tecnologia
2012/04 - 2015/08
Non-invasive-Non-viral Silencing of Machado-Joseph disease
grant.Provided by PTCRIS: 116535
Researcher
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Funders: Fundação para a Ciência e a Tecnologia
2009/07 - 2011/12
Advancing the field of drug delivery - combined targeted treatments against human breast cancer and human leukemia (The OncotargetNanoMed network)
grant.Provided by PTCRIS: 109361
Researcher
Universidade de Coimbra Centro de Neurociências e Biologia Celular; Universidade de Coimbra Faculdade de Ciencias e Tecnologia; Universidade de Aveiro; Universidade do Minho; Universidade de Lisboa Faculdade de Farmácia
Funders: Fundação para a Ciência e a Tecnologia
2005/07 - 2008/06
DNA manipulation in bulk and at interfaces
grant.Provided by PTCRIS: 58689
Researcher
Universidade de Coimbra Faculdade de Ciencias e Tecnologia; Universidade de Coimbra Centro de Química de Coimbra; Universidade de Coimbra Centro de Neurociências e Biologia Celular
Funders: Fundação para a Ciência e a Tecnologia
5 16 out of 16 projects
We use cookies to improve your visit to our website.