Liliana Mendonça

Lysosomal Storage Disease-Associated Neuropathy: Targeting Stable Nucleic Acid Lipid Particle (SNALP)-Formulated siRNAs to the Brain as a Therapeutic Approach

Coutinho, Maria Francisca; Santos, Juliana Inês; S. Mendonça, Liliana; Matos, Liliana; Prata, Maria João; S. Jurado, Amália; Pedroso de Lima, Maria C.; Alves, Sandra, International Journal of Molecular Sciences. 16. 21. 2020. http://dx.doi.org/10.3390/ijms21165732 . 10.3390/ijms21165732 . published International Journal of Molecular Sciences

RNA Interference Therapy for Machado-Joseph Disease: Long-Term Safety Profile of Lentiviral Vectors Encoding Short Hairpin RNAs Targeting Mutant Ataxin-3

Nóbrega, Clévio; Codêsso, José Miguel; Mendonça, Liliana; Pereira de Almeida, Luís, Human Gene Therapy. 841 - 854. 7. 30. 2019. http://dx.doi.org/10.1089/hum.2018.157 . 10.1089/hum.2018.157 . published Human Gene Therapy

Ibuprofen enhances synaptic function and neural progenitors proliferation markers and improves neuropathology and motor coordination in Machado–Joseph disease models

Mendonça, Liliana S; Nóbrega, Clévio; Tavino, Silvia; Brinkhaus, Maximilian; Matos, Carlos; Tomé, Sandra; Moreira, Ricardo; et al, Human Molecular Genetics. 3691 - 3703. 22. 28. 2019. http://dx.doi.org/10.1093/hmg/ddz097 . 10.1093/hmg/ddz097 . Human Molecular Genetics

Restoring brain cholesterol turnover improves autophagy and has therapeutic potential in mouse models of spinocerebellar ataxia

Nóbrega, Clévio; Mendonça, Liliana; Marcelo, Adriana; Lamazière, Antonin; Tomé, Sandra; Despres, Gaetan; Matos, Carlos A.; et al, Acta Neuropathologica. 837 - 858. 5. 138. 2019. http://dx.doi.org/10.1007/s00401-019-02019-7 . 10.1007/s00401-019-02019-7 . published Acta Neuropathologica

Understanding how birds rebuild fat stores during migration: insights from an experimental study

Araújo, Pedro M.; Viegas, Ivan; Rocha, Afonso D.; Villegas, Auxiliadora; Jones, John G.; Mendonça, Liliana; Ramos, Jaime A.; Masero, José A.; Alves, José A., Scientific Reports. 1. 9. 2019. http://dx.doi.org/10.1038/s41598-019-46487-z . 10.1038/s41598-019-46487-z . published Scientific Reports

Cordycepin activates autophagy through AMPK phosphorylation to reduce abnormalities in Machado-Joseph disease models

Marcelo, Adriana; Brito, Filipa; Carmo-Silva, Sara; Matos, Carlos A; Alves-Cruzeiro, João; Vasconcelos-Ferreira, Ana; Koppenol, Rebekah; et al, Human Molecular Genetics. 51 - 63. 1. 28. 2018. http://dx.doi.org/10.1093/hmg/ddy328 . 10.1093/hmg/ddy328 . Human Molecular Genetics

Motor Dysfunctions and Neuropathology in Mouse Models of Spinocerebellar Ataxia Type 2: A Comprehensive Review

Alves-Cruzeiro, João M. Da Conceição; Mendonça, Liliana; Pereira de Almeida, Luís; Nóbrega, Clévio, Frontiers in Neuroscience. 10. 2016. http://dx.doi.org/10.3389/fnins.2016.00572 . 10.3389/fnins.2016.00572 . published Frontiers in Neuroscience

Safety profile of the intravenous administration of brain-targeted stable nucleic acid lipid particles

Conceição, M.; Mendonça, L.; Nóbrega, C.; Gomes, C.; Costa, P.; Hirai, H.; Moreira, J.N.; et al, Data in Brief. 700 - 705. 6. 2016. http://www.scopus.com/inward/record.url?eid=2-s2.0-84956617357&partnerID=MN8TOARS . 10.1016/j.dib.2016.01.017 . Data in Brief

Intravenous administration of brain-targeted stable nucleic acid lipid particles alleviates Machado-Joseph disease neurological phenotype

Conceição, M.; Mendonça, L.; Nóbrega, C.; Gomes, C.; Costa, P.; Hirai, H.; Moreira, J.N.; et al, Biomaterials. 124 - 137. 82. 2016. http://www.scopus.com/inward/record.url?eid=2-s2.0-84956644943&partnerID=MN8TOARS . 10.1016/j.biomaterials.2015.12.021 . published Biomaterials

Re-establishing ataxin-2 downregulates translation of mutant ataxin-3 and alleviates Machado-Joseph disease

Nóbrega, C.; Carmo-Silva, S.; Albuquerque, D.; Vasconcelos-Ferreira, A.; Vijayakumar, U.-G.; Mendonça, L.; Hirai, H.; Pereira De Almeida, L., Brain. 3537 - 3554. 12. 138. 2015. http://www.scopus.com/inward/record.url?eid=2-s2.0-84951031850&partnerID=MN8TOARS . 10.1093/brain/awv298 . published Brain

Transplantation of cerebellar neural stem cells improves motor coordination and neuropathology in Machado-Joseph disease mice

Mendonça, Liliana S.; Nóbrega, Clévio; Hirai, Hirokazu; Kaspar, Brian K.; Pereira de Almeida, Luís, Brain. 320 - 335. 2. 138. 2014. http://dx.doi.org/10.1093/brain/awu352 . 10.1093/brain/awu352 . published Brain

Tumor-targeted Chlorotoxin-coupled Nanoparticles for Nucleic Acid Delivery to Glioblastoma Cells: A Promising System for Glioblastoma Treatment

Costa, Pedro M; Cardoso, Ana L; Mendonça, Liliana S; Serani, Angelo; Custódia, Carlos; Conceição, Mariana; Simões, Sérgio; et al, Molecular Therapy - Nucleic Acids. 2. 2013. http://dx.doi.org/10.1038/mtna.2013.30 . 10.1038/mtna.2013.30 . published Molecular Therapy - Nucleic Acids

Targeted lipid-based systems for siRNA delivery

Mendonça, L.S.; Pedroso de Lima, M.C.; Simões, S., Journal of Drug Delivery Science and Technology. 65 - 73. 1. 22. 2012. http://dx.doi.org/10.1016/s1773-2247(12)50006-7 . 10.1016/s1773-2247(12)50006-7 . published Journal of Drug Delivery Science and Technology

Transferrin Receptor-Targeted Liposomes Encapsulating anti-BCR-ABLsiRNA or asODN for Chronic Myeloid Leukemia Treatment

Mendonça, Liliana S.; Firmino, Filipe; Moreira, João N.; Pedroso de Lima, Maria C.; Simões, Sérgio, Bioconjugate Chemistry. 157 - 168. 1. 21. 2010. http://dx.doi.org/10.1021/bc9004365 . 10.1021/bc9004365 . published Bioconjugate Chemistry

Co-encapsulation of anti-BCR-ABL siRNA and imatinib mesylate in transferrin receptor-targeted sterically stabilized liposomes for chronic myeloid leukemia treatment

Mendonça, Liliana S.; Moreira, João N.; de Lima, Maria C. Pedroso; Simões, Sérgio, Biotechnology and Bioengineering. 884 - 893. 5. 107. 2010. http://dx.doi.org/10.1002/bit.22858 . 10.1002/bit.22858 . published Biotechnology and Bioengineering