PDBEB Courses 2022/2023 - Neuroscience - From Synapses to Circuits and Brain Diseases (Module 2 - Neuronal Circuits and Behavior)

Organized by

Center for Neuroscience and Cell Biology

Date & Time

23/01/2023 - 27/01/2023

Location

CNC, Polo I, FMUC building - Auditorium 2º F

Registation

Mandatory

Deadline : 10/01/2023

Register

Aim

The goal of the PDBEB Advanced Courses in Neuroscience is to provide an integrated view into both the physiological processes of neuronal synapses and circuits, and their dysfunction in neuropsychiatric and neurodegenerative diseases. In tandem with theoretical courses taught by international experts in the field, these advanced courses will include multiple intensive practical workshops. Students will attend theoretical and methodological lectures during the morning, and spend the afternoon performing hands-on projects in groups of 2-3 students.

In module 2 on Neuronal Circuits and Behavior, the following topics will be addressed: 

- Synaptic transmission in the hippocampal circuit
- Whole-cell recordings
- Optogenetics
- In vivo recordings
- Cerebellar circuits
- Thalamic circuits
- Cortical circuits
- Behavioral analysis
- Neurodevelopmental disorders
 

Experimental projects include:

P2.1. Growth and analysis of human brain organoids (Catarina Seabra & Ana Maria Cardoso).
P2.2. Electrophysiological analysis of the cerebellar microcircuitry in adult mice (Joana Guedes & Pedro Ferreira).
P2.3. Analysis of Parvalbumin-positive interneurons in hippocampal slices (Mariana Laranjo).
P2.4. Electrophysiology recordings in live-behaving mice (Emanuel Ferreira-Fernandes & Tiago Reis).
P2.5. Optogenetics and closed-loop behavioral manipulation (Tiago Reis).
P2.6. Unbiased, Golgi-like labeling of neurons without the Golgi staining method (Jéssica Costa).
P2.7. Impact of silencing astrocytes on inhibitory modulation of glutamatergic synapses (Cátia Lopes & Angelo Tomé)
P2.8. Labeling and isolation of microglia from the mouse brain (Ana Luisa Cardoso & Joana Guedes).
P2.9. Neurovascular coupling functionality and cognitive enhancement (Cátia Marques & João Laranjinha).

Program

Available here.

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