Publicações
Informação sobre artigos em revista, actualizada a 18-04-2024, a partir da plataforma CIÊNCIAVITAE.
Aberrant hippocampal transmission and behavior in mice with a stargazin mutation linked to intellectual disability
Caldeira, G. L.; Inácio, A. S.; Beltrão, N.; Barreto, C. A. V.; Rodrigues, M. V.; Rondão, T.; Macedo, R.; et al, Molecular Psychiatry. 2022. http://dx.doi.org/10.1038/s41380-022-01487-w . 10.1038/s41380-022-01487-w . Molecular Psychiatry
Interplay between NMDA receptor dynamics and the synaptic proteasome
Joana S. Ferreira; Blanka Kellermayer; Ana Luísa Carvalho; Laurent Groc, European Journal of Neuroscience. 6000 - 6011. 6. 54. 2021. https://doi.org/10.1111/ejn.15427 . 10.1111/ejn.15427 . European Journal of Neuroscience
It takes two to tango: Concerted protein translation and degradation necessary for synaptic scaling
Ana Luisa Carvalho; Dominique Fernandes, PLOS Biology. 2021. https://doi.org/10.1371/journal.pbio.3001448 . 10.1371/journal.pbio.3001448 . PLOS Biology
Ligand-independent activity of the ghrelin receptor modulates AMPA receptor trafficking and supports memory formation
Ribeiro, Luís F.; Catarino, Tatiana; Carvalho, Mário; Cortes, Luísa; Santos, Sandra D.; Opazo, Patricio O.; Ribeiro, Lyn Rosenbrier; et al, Science Signaling. 670. 14. 2021. http://dx.doi.org/10.1126/scisignal.abb1953 . 10.1126/scisignal.abb1953 . Science Signaling
Abnormal mGluR-mediated synaptic plasticity and autism-like behaviours in Gprasp2 mutant mice
Edfawy, Mohamed; Guedes, Joana R.; Pereira, Marta I.; Laranjo, Mariana; Carvalho, Mário J.; Gao, Xian; Ferreira, Pedro A.; et al, Nature Communications. 1. 10. 2019. http://dx.doi.org/10.1038/s41467-019-09382-9 . 10.1038/s41467-019-09382-9 . Nature Communications
Disrupted AMPA Receptor Function upon Genetic- or Antibody-Mediated Loss of Autism-Associated CASPR2
Dominique Fernandes; Sandra D Santos; Ester Coutinho; Jessica L Whitt; Nuno Beltrão; Tiago Rondão; M Isabel Leite; et al, Cerebral Cortex. 2019. https://doi.org/10.1093/cercor/bhz032 . 10.1093/cercor/bhz032 . Cerebral Cortex
The role of ghrelin in regulating synaptic function and plasticity of feeding-associated circuits
Serrenho, D.; Santos, S.D.; Carvalho, A.L., Frontiers in Cellular Neuroscience. 13. 2019. http://www.scopus.com/inward/record.url?eid=2-s2.0-85068476880&partnerID=MN8TOARS . 10.3389/fncel.2019.00205 . Frontiers in Cellular Neuroscience
New insights on synaptic dysfunction in neuropsychiatric disorders
Lima Caldeira, G.; Peça, J.; Carvalho, A.L., Current Opinion in Neurobiology. 62 - 70. 57. 2019. http://www.scopus.com/inward/record.url?eid=2-s2.0-85061115086&partnerID=MN8TOARS . 10.1016/j.conb.2019.01.004 . Current Opinion in Neurobiology
MicroRNA-186-5p controls GluA2 surface expression and synaptic scaling in hippocampal neurons
Mariline M. Silva; Beatriz Rodrigues; Joana Fernandes; Sandra D. Santos; Laura Carreto; Manuel A. S. Santos; Paulo Pinheiro; et al, Proceedings of the National Academy of Sciences. 5727 - 5736. 12. 116. 2019. https://doi.org/10.1073/pnas.1900338116 . 10.1073/pnas.1900338116 . published Proceedings of the National Academy of Sciences
Stargazin Dephosphorylation Mediates Homeostatic Synaptic Downscaling of Excitatory Synapses
Louros, S.R.; Caldeira, G.L.; Carvalho, A.L., Frontiers in Molecular Neuroscience. 11. 2018. http://www.scopus.com/inward/record.url?eid=2-s2.0-85054810796&partnerID=MN8TOARS . 10.3389/fnmol.2018.00328 . Frontiers in Molecular Neuroscience
Differential Nanoscale Topography and Functional Role of GluN2-NMDA Receptor Subtypes at Glutamatergic Synapses
Kellermayer, B.; Ferreira, J.S.; Dupuis, J.; Levet, F.; Grillo-Bosch, D.; Bard, L.; Linarès-Loyez, J.; et al, Neuron. 106 - 119.e7. 1. 100. 2018. http://www.scopus.com/inward/record.url?eid=2-s2.0-85054706658&partnerID=MN8TOARS . 10.1016/j.neuron.2018.09.012 . Neuron
Metabotropic glutamate type 5 receptor requires contactin-associated protein 1 to control memory formation
Morató, X.; Luján, R.; Gonçalves, N.; Watanabe, M.; Altafaj, X.; Carvalho, A.L.; Fernández-Dueñas, V.; Cunha, R.A.; Ciruela, F., Human Molecular Genetics. 3528 - 3541. 20. 27. 2018. http://www.scopus.com/inward/record.url?eid=2-s2.0-85054354803&partnerID=MN8TOARS . 10.1093/hmg/ddy264 . Human Molecular Genetics
Mechanisms of homeostatic plasticity in the excitatory synapse
Dominique Fernandes; Ana Luísa Carvalho, Journal of Neurochemistry. 2016. http://dx.doi.org/10.1111/jnc.13687 . 10.1111/jnc.13687 . Journal of Neurochemistry
7th ISN special neurochemistry conference ‘Synaptic function and dysfunction in brain diseases’
Carlos B. Duarte; Ana Luisa Carvalho, Journal of Neurochemistry. 2016. http://dx.doi.org/10.1111/jnc.13839 . 10.1111/jnc.13839 . Journal of Neurochemistry
Multiple domains in the C-terminus of NMDA receptor GluN2B subunit contribute to neuronal death following in vitro ischemia
Vieira, M.M.; Schmidt, J.; Ferreira, J.S.; She, K.; Oku, S.; Mele, M.; Santos, A.E.; et al, Neurobiology of Disease. 223 - 234. 89. 2016. http://www.scopus.com/inward/record.url?eid=2-s2.0-84959360132&partnerID=MN8TOARS . 10.1016/j.nbd.2015.11.007 . Neurobiology of Disease
Ataxin-3 phosphorylation decreases neuronal defects in spinocerebellar ataxia type 3 models
Matos, C.A.; Nóbrega, C.; Louros, S.R.; Almeida, B.; Ferreiro, E.; Valero, J.; De Almeida, L.P.; Macedo-Ribeiro, S.; Carvalho, A.L., Journal of Cell Biology. 465 - 480. 4. 212. 2016. http://www.scopus.com/inward/record.url?eid=2-s2.0-84959536774&partnerID=MN8TOARS . 10.1083/jcb.201506025 . Journal of Cell Biology
Biotinylation and Purification of Plasma Membrane-associated Proteins from Rodent Cultured Neurons
Caldeira, Margarida; Ferreira, Joana; Carvalho, Ana; Duarte, Carlos, BIO-PROTOCOL. 10. 6. 2016. http://dx.doi.org/10.21769/bioprotoc.1807 . 10.21769/bioprotoc.1807 . BIO-PROTOCOL
GluN2B-containing NMDA receptors regulate AMPA receptor traffic through anchoring of the synaptic proteasome
Ferreira, J.S.; Schmidt, J.; Rio, P.; Águas, R.; Rooyakkers, A.; Li, K.W.; Smit, A.B.; Craig, A.M.; Carvalho, A.L., Journal of Neuroscience. 8462 - 8479. 22. 35. 2015. http://www.scopus.com/inward/record.url?eid=2-s2.0-84930427217&partnerID=MN8TOARS . 10.1523/JNEUROSCI.3567-14.2015 . Journal of Neuroscience
Aß and NMDAR activation cause mitochondrial dysfunction involving ER calcium release
Ferreira, I.L.; Ferreiro, E.; Schmidt, J.; Cardoso, J.M.; Pereira, C.M.F.; Carvalho, A.L.; Oliveira, C.R.; Rego, A.C., Neurobiology of Aging. 680 - 692. 2. 36. 2015. http://www.scopus.com/inward/record.url?eid=2-s2.0-84922927392&partnerID=MN8TOARS . 10.1016/j.neurobiolaging.2014.09.006 . Neurobiology of Aging
SUMOylation of the brain-predominant Ataxin-3 isoform modulates its interaction with p97
Almeida, B.; Abreu, I.A.; Matos, C.A.; Fraga, J.S.; Fernandes, S.; Macedo, M.G.; Gutiérrez-Gallego, R.; et al, Biochimica et Biophysica Acta - Molecular Basis of Disease. 1950 - 1959. 9. 1852. 2015. http://www.scopus.com/inward/record.url?eid=2-s2.0-84955513053&partnerID=MN8TOARS . 10.1016/j.bbadis.2015.06.010 . Biochimica et Biophysica Acta - Molecular Basis of Disease
A role for stargazin in experience-dependent plasticity
Louros, S.; Hooks, B.; Litvina, L.; Carvalho, A.; Chen, C., Cell Reports. 1614 - 1625. 5. 7. 2014. http://www.scopus.com/inward/record.url?eid=2-s2.0-84902344846&partnerID=MN8TOARS . 10.1016/j.celrep.2014.04.054 . Cell Reports
Impaired Src signaling and post-synaptic actin polymerization in Alzheimer's disease mice hippocampus - Linking NMDA receptors and the reelin pathway
Mota, S.I.; Ferreira, I.L.; Valero, J.; Ferreiro, E.; Carvalho, A.L.; Oliveira, C.R.; Rego, A.C., Experimental Neurology. 698 - 709. 261. 2014. http://www.scopus.com/inward/record.url?eid=2-s2.0-84908339906&partnerID=MN8TOARS . 10.1016/j.expneurol.2014.07.023 . Experimental Neurology
In vitro ischemia triggers a transcriptional response to down-regulate synaptic proteins in hippocampal neurons
Fernandes, J.; Vieira, M.; Carreto, L.; Santos, M.A.S.; Duarte, C.B.; Carvalho, A.L.; Santos, A.E., PLoS ONE. 6. 9. 2014. http://www.scopus.com/inward/record.url?eid=2-s2.0-84903512303&partnerID=MN8TOARS . 10.1371/journal.pone.0099958 . PLoS ONE
Diabetes causes transient changes in the composition and phosphorylation of a-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors and interaction with auxiliary proteins in the rat retina
Castilho, A.F.; Liberal, J.T.; Baptista, F.I.; Gaspar, J.M.; Carvalho, A.L.; Ambrósio, A.F., Molecular Vision. 894 - 907. 20. 2014. http://www.scopus.com/inward/record.url?eid=2-s2.0-84903118075&partnerID=MN8TOARS . Molecular Vision
Ghrelin triggers the synaptic incorporation of AMPA receptors in the hippocampus
Ribeiro, L.F.; Catarino, T.; Santos, S.D.; Benoist, M.; Van Leeuwen, J.F.; Esteban, J.A.; Carvalho, A.L., Proceedings of the National Academy of Sciences of the United States of America. 1. 111. 2014. http://www.scopus.com/inward/record.url?eid=2-s2.0-84891958005&partnerID=MN8TOARS . 10.1073/pnas.1313798111 . Proceedings of the National Academy of Sciences of the United States of America
Ischemic insults induce necroptotic cell death in hippocampal neurons through the up-regulation of endogenous RIP3
Vieira, M.; Fernandes, J.; Carreto, L.; Anuncibay-Soto, B.; Santos, M.; Han, J.; Fernández-López, A.; et al, Neurobiology of Disease. 26 - 36. 68. 2014. http://www.scopus.com/inward/record.url?eid=2-s2.0-84899850247&partnerID=MN8TOARS . 10.1016/j.nbd.2014.04.002 . Neurobiology of Disease
Regulation of synapse composition by protein acetylation: The role of acetylated cortactin
Catarino, T.; Ribeiro, L.; Santos, S.D.; Carvalho, A.L., Journal of Cell Science. 149 - 162. 1. 126. 2013. http://www.scopus.com/inward/record.url?eid=2-s2.0-84875621271&partnerID=MN8TOARS . 10.1242/jcs.110742 . Journal of Cell Science
Glutamate Binding to the GluN2B Subunit Controls Surface Trafficking of N-Methyl-D-aspartate (NMDA) Receptors
She, Kevin; Ferreira, Joana S.; Carvalho, Ana Luisa; Craig, Ann Marie, Journal of Biological Chemistry. 27432 - 27445. 33. 287. 2012. 10.1074/jbc.M112.345108 . Journal of Biological Chemistry
Elevated glucose concentration changes the content and cellular localization of AMPA receptors in the retina but not in the hippocampus
Castilho, A.F.; Liberal, J.T.; Baptista, F.I.; Gaspar, J.M.; Carvalho, A.L.; Ambrósio, A.F., Neuroscience. 23 - 32. 219. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84864022057&partnerID=MN8TOARS . 10.1016/j.neuroscience.2012.05.056 . Neuroscience
Contactin-associated protein 1 (Caspr1) regulates the traffic and synaptic content of a-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)-type glutamate receptors
Santos, S.D.; Iuliano, O.; Ribeiro, L.; Veran, J.; Ferreira, J.S.; Rio, P.; Mulle, C.; Duarte, C.B.; Carvalho, A.L., Journal of Biological Chemistry. 6868 - 6877. 9. 287. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84857468361&partnerID=MN8TOARS . 10.1074/jbc.M111.322909 . Journal of Biological Chemistry
Cleavage of the vesicular glutamate transporters under excitotoxic conditions
Lobo, A.C.; Gomes, J.R.; Catarino, T.; Mele, M.; Fernandez, P.; Inácio, A.R.; Bahr, B.A.; et al, Neurobiology of Disease. 292 - 303. 3. 44. 2011. http://www.scopus.com/inward/record.url?eid=2-s2.0-80053269066&partnerID=MN8TOARS . 10.1016/j.nbd.2011.07.010 . Neurobiology of Disease
Polyglutamine diseases: The special case of ataxin-3 and Machado-Joseph disease
Matos, C.A.; de Macedo-Ribeiro, S.; Carvalho, A.L., Progress in Neurobiology. 26 - 48. 1. 95. 2011. http://www.scopus.com/inward/record.url?eid=2-s2.0-79960668226&partnerID=MN8TOARS . 10.1016/j.pneurobio.2011.06.007 . Progress in Neurobiology
Activity and protein kinase C regulate synaptic accumulation of N-Methyl-D-aspartate (NMDA) receptors independently of GluN1 splice variant
Ferreira, J.S.; Rooyakkers, A.; She, K.; Ribeiro, L.; Carvalho, A.L.; Craig, A.M., Journal of Biological Chemistry. 28331 - 28342. 32. 286. 2011. http://www.scopus.com/inward/record.url?eid=2-s2.0-80051515440&partnerID=MN8TOARS . 10.1074/jbc.M111.222539 . Journal of Biological Chemistry
Excitotoxicity through Ca2+-permeable AMPA receptors requires Ca2+-dependent JNK activation
Vieira, M.; Fernandes, J.; Burgeiro, A.; Thomas, G.M.; Huganir, R.L.; Duarte, C.B.; Carvalho, A.L.; Santos, A.E., Neurobiology of Disease. 645 - 655. 3. 40. 2010. http://www.scopus.com/inward/record.url?eid=2-s2.0-77957795389&partnerID=MN8TOARS . 10.1016/j.nbd.2010.08.008 . Neurobiology of Disease
Proteomic analysis of an interactome for long-form AMPA receptor subunits
Santos, S.D.; Manadas, B.; Duarte, C.B.; Carvalho, A.L., Journal of Proteome Research. 1670 - 1682. 4. 9. 2010. http://www.scopus.com/inward/record.url?eid=2-s2.0-77950666645&partnerID=MN8TOARS . 10.1021/pr900766r . Journal of Proteome Research
Leptin regulates AMPA receptor trafficking via PTEN inhibition
Moult, P.R.; Cross, A.; Santos, S.D.; Carvalho, A.-L.; Lindsay, Y.; Connolly, C.N.; Irving, A.J.; Leslie, N.R.; Harvey, J., Journal of Neuroscience. 4088 - 4101. 11. 30. 2010. http://www.scopus.com/inward/record.url?eid=2-s2.0-77949725839&partnerID=MN8TOARS . 10.1523/JNEUROSCI.3614-09.2010 . Journal of Neuroscience
Regulation of AMPA receptors and synaptic plasticity
Santos, S.D.; Carvalho, A.L.; Caldeira, M.V.; Duarte, C.B., Neuroscience. 105 - 125. 1. 158. 2009. http://www.scopus.com/inward/record.url?eid=2-s2.0-58149467917&partnerID=MN8TOARS . 10.1016/j.neuroscience.2008.02.037 . Neuroscience
Nucleocytoplasmic shuttling activity of ataxin-3
Macedo-Ribeiro, S.; Cortes, L.; Maciel, P.; Carvalho, A.L., PLoS ONE. 6. 4. 2009. http://www.scopus.com/inward/record.url?eid=2-s2.0-67149129949&partnerID=MN8TOARS . 10.1371/journal.pone.0005834 . PLoS ONE
African swine fever virus p10 protein exhibits nuclear import capacity and accumulates in the nucleus during viral infection
Nunes-Correia, I.; Rodríguez, J.M.; Eulálio, A.; Carvalho, A.L.; Citovsky, V.; Simões, S.; Faro, C.; Salas, M.L.; Pedroso de Lima, M.C., Veterinary Microbiology. 47 - 59. 1-2. 130. 2008. http://www.scopus.com/inward/record.url?eid=2-s2.0-46549086170&partnerID=MN8TOARS . 10.1016/j.vetmic.2007.12.010 . Veterinary Microbiology
Role of the brain-derived neurotrophic factor at glutamatergic synapses
Carvalho, A.L.; Caldeira, M.V.; Santos, S.D.; Duarte, C.B., British Journal of Pharmacology. SUPPL. 1. 153. 2008. http://www.scopus.com/inward/record.url?eid=2-s2.0-40349114504&partnerID=MN8TOARS . 10.1038/sj.bjp.0707509 . British Journal of Pharmacology
Characterization of alternatively spliced isoforms of AMPA receptor subunits encoding truncated receptors
Gomes, A.R.; Ferreira, J.S.; Paternain, A.V.; Lerma, J.; Duarte, C.B.; Carvalho, A.L., Molecular and Cellular Neuroscience. 323 - 334. 2. 37. 2008. http://www.scopus.com/inward/record.url?eid=2-s2.0-38749131588&partnerID=MN8TOARS . 10.1016/j.mcn.2007.10.008 . Molecular and Cellular Neuroscience
Striatal and nigral pathology in a lentiviral rat model of Machado-Joseph disease
Alves, S.; Régulier, E.; Nascimento-Ferreira, I.; Hassig, R.; Dufour, N.; Koeppen, A.; Carvalho, A.L.; et al, Human Molecular Genetics. 2071 - 2083. 14. 17. 2008. http://www.scopus.com/inward/record.url?eid=2-s2.0-46249122383&partnerID=MN8TOARS . 10.1093/hmg/ddn106 . Human Molecular Genetics
PKC anchoring to GluR4 AMPA receptor subunit modulates PKC-driven receptor phosphorylation and surface expression
Gomes, A.R.; Correia, S.S.; Esteban, J.A.; Duarte, C.B.; Carvalho, A.L., Traffic. 259 - 269. 3. 8. 2007. http://www.scopus.com/inward/record.url?eid=2-s2.0-34247490214&partnerID=MN8TOARS . 10.1111/j.1600-0854.2006.00521.x . Traffic
NPY in rat retina is present in neurons, in endothelial cells and also in microglial and Müller cells
Álvaro, A.R.; Rosmaninho-Salgado, J.; Santiago, A.R.; Martins, J.; Aveleira, C.; Santos, P.F.; Pereira, T.; et al, Neurochemistry International. 757 - 763. 5. 50. 2007. http://www.scopus.com/inward/record.url?eid=2-s2.0-33947389655&partnerID=MN8TOARS . 10.1016/j.neuint.2007.01.010 . Neurochemistry International
NEDD8: A new ataxin-3 interactor
Ferro, A.; Carvalho, A.L.; Teixeira-Castro, A.; Almeida, C.; Tomé, R.J.; Cortes, L.; Rodrigues, A.-J.; et al, Biochimica et Biophysica Acta - Molecular Cell Research. 1619 - 1627. 11. 1773. 2007. http://www.scopus.com/inward/record.url?eid=2-s2.0-35548938484&partnerID=MN8TOARS . 10.1016/j.bbamcr.2007.07.012 . Biochimica et Biophysica Acta - Molecular Cell Research
BDNF regulates the expression and traffic of NMDA receptors in cultured hippocampal neurons
Caldeira, M.V.; Melo, C.V.; Pereira, D.B.; Carvalho, R.F.; Carvalho, A.L.; Duarte, C.B., Molecular and Cellular Neuroscience. 208 - 219. 2. 35. 2007. http://www.scopus.com/inward/record.url?eid=2-s2.0-34249712975&partnerID=MN8TOARS . 10.1016/j.mcn.2007.02.019 . Molecular and Cellular Neuroscience
Brain-derived neurotrophic factor regulates the expression and synaptic delivery of a-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptor subunits in hippocampal neurons
Caldeira, M.V.; Melo, C.V.; Pereira, D.B.; Carvalho, R.; Correia, S.S.; Backos, D.S.; Carvalho, A.L.; Esteban, J.A.; Duarte, C.B., Journal of Biological Chemistry. 12619 - 12628. 17. 282. 2007. http://www.scopus.com/inward/record.url?eid=2-s2.0-34250329980&partnerID=MN8TOARS . 10.1074/jbc.M700607200 . Journal of Biological Chemistry
Erratum: Brain-derived neurotrophic factor regulates the expression and synaptic delivery of a-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptor subunits in hippocampal neurons (Journal of Biological Chemistry (2007) 282, (12619-12628))
Caldeira, M.V.; Melo, C.V.; Pereira, D.B.; Carvalho, R.; Correia, S.S.; Backos, D.S.; Carvalho, A.L.; Esteban, J.A.; Duarte, C.B., Journal of Biological Chemistry. 37. 282. 2007. http://www.scopus.com/inward/record.url?eid=2-s2.0-34848900818&partnerID=MN8TOARS . Journal of Biological Chemistry
Purification of a novel aminopeptidase from the pollen of Parietaria judaica that alters epithelial integrity and degrades neuropeptides
Cortes, L.; Carvalho, A.L.; Todo-Bom, A.; Faro, C.; Pires, E.; Veríssimo, P., Journal of Allergy and Clinical Immunology. 878 - 884. 4. 118. 2006. http://www.scopus.com/inward/record.url?eid=2-s2.0-33749349447&partnerID=MN8TOARS . 10.1016/j.jaci.2006.05.029 . Journal of Allergy and Clinical Immunology
Excitotoxicity mediated by Ca2+-permeable GluR4-containing AMPA receptors involves the AP-1 transcription factor
Santos, A.E.; Duarte, C.B.; Iizuka, M.; Barsoumian, E.L.; Ham, J.; Lopes, M.C.; Carvalho, A.P.; Carvalho, A.L., Cell Death and Differentiation. 652 - 660. 4. 13. 2006. http://www.scopus.com/inward/record.url?eid=2-s2.0-33644935364&partnerID=MN8TOARS . 10.1038/sj.cdd.4401785 . Cell Death and Differentiation
Nuclear export of African swine fever virus p37 protein occurs through two distinct pathways and is mediated by three independent signals
Eulálio, A.; Nunes-Correia, I.; Carvalho, A.L.; Faro, C.; Citovsky, V.; Salas, J.; Salas, M.L.; Simões, S.; Pedroso De Lima, M.C., Journal of Virology. 1393 - 1404. 3. 80. 2006. http://www.scopus.com/inward/record.url?eid=2-s2.0-31144441675&partnerID=MN8TOARS . 10.1128/JVI.80.3.1393-1404.2006 . Journal of Virology
Downregulation of retinal GLUT1 in diabetes by ubiquitinylation
Fernandes, R.; Carvalho, A.L.; Kumagai, A.; Seica, R.; Hosoya, K.-I.; Terasaki, T.; Murta, J.; Pereira, P.; Faro, C., Molecular Vision. 618 - 628. 10. 2004. http://www.scopus.com/inward/record.url?eid=2-s2.0-16544391719&partnerID=MN8TOARS . Molecular Vision
Metabotropic glutamate and dopamine receptors co-regulate AMPA receptor activity through PKA in cultured chick retinal neurones: Effect on GluR4 phosphorylation and surface expression
Gomes, A.R.; Cunha, P.; Nuriya, M.; Faro, C.J.; Huganir, R.L.; Pires, E.V.; Carvalho, A.L.; Duarte, C.B., Journal of Neurochemistry. 673 - 682. 3. 90. 2004. http://www.scopus.com/inward/record.url?eid=2-s2.0-3342901599&partnerID=MN8TOARS . 10.1111/j.1471-4159.2004.02519.x . Journal of Neurochemistry
Two African swine fever virus proteins derived from a common precursor exhibit different nucleocytoplasmic transport activities
Eulálio, A.; Nunes-Correia, I.; Carvalho, A.L.; Faro, C.; Citovsky, V.; Simões, S.; De Lima, M.C.P., Journal of Virology. 9731 - 9739. 18. 78. 2004. http://www.scopus.com/inward/record.url?eid=2-s2.0-4444281591&partnerID=MN8TOARS . 10.1128/JVI.78.18.9731-9739.2004 . Journal of Virology
Regulation of AMPA receptor activity, synaptic targeting and recycling: Role in synaptic plasticity
Gomes, A.R.; Correia, S.S.; Carvalho, A.L.; Duarte, C.B., Neurochemical Research. 1459 - 1473. 10. 28. 2003. http://www.scopus.com/inward/record.url?eid=2-s2.0-0141705374&partnerID=MN8TOARS . 10.1023/A:1025610122776 . Neurochemical Research
Protein kinase C¿ associates directly with the GluR4 a-amino-3-hydroxy-5-methyl-4-isoxazole propionate receptor subunit: Effect on receptor phosphorylation
Santos Correia, S.; Bandeira Duarte, C.; Faro, C.J.; Vieira Pires, E.; Carvalho, A.L., Journal of Biological Chemistry. 6307 - 6313. 8. 278. 2003. http://www.scopus.com/inward/record.url?eid=2-s2.0-0037458663&partnerID=MN8TOARS . 10.1074/jbc.M205587200 . Journal of Biological Chemistry
Phosphorylation of GluR4 AMPA-type glutamate receptor subunit by protein kinase C in cultured retina amacrine neurons
Carvalho, A.L.; Correia, S.; Faro, C.J.; Duarte, C.B.; Carvalho, A.P.; Pires, E.M.V., European Journal of Neuroscience. 465 - 474. 3. 15. 2002. http://www.scopus.com/inward/record.url?eid=2-s2.0-0036456320&partnerID=MN8TOARS . 10.1046/j.0953-816x.2001.01881.x . European Journal of Neuroscience
Differential postreceptor signaling events triggered by excitotoxic stimulation of different ionotropic glutamate receptors in retinal Neurons
Santos, A.E.; Carvalho, A.L.; Lopes, M.C.; Carvalho, A.P., Journal of Neuroscience Research. 643 - 655. 4. 66. 2001. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035889524&partnerID=MN8TOARS . 10.1002/jnr.10036 . Journal of Neuroscience Research
Regulation of AMPA Receptors by Phosphorylation
Carvalho, A.L.; Duarte, C.B.; Carvalho, A.P., Neurochemical Research. 1245 - 1255. 9-10. 25. 2000. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034304035&partnerID=MN8TOARS . Neurochemical Research
Characterization of phosphorylation sites on the glutamate receptor 4 subunit of the AMPA receptors
Carvalho, A.L.; Kameyama, K.; Huganir, R.L., Journal of Neuroscience. 4748 - 4754. 12. 19. 1999. http://www.scopus.com/inward/record.url?eid=2-s2.0-0033564041&partnerID=MN8TOARS . Journal of Neuroscience
Differential acetylcholine and GABA release from cultured chick retina cells
Santos, P.F.; Carvalho, A.L.; Carvalho, A.P.; Duarte, C.B., European Journal of Neuroscience. 2723 - 2730. 8. 10. 1998. http://www.scopus.com/inward/record.url?eid=2-s2.0-0031927252&partnerID=MN8TOARS . 10.1046/j.1460-9568.1998.00281.x . European Journal of Neuroscience
Calcium influx through AMPA receptors and through calcium channels is regulated by protein kinase C in cultured retina amacrine-like cells
Carvalho, A.L.; Duarte, C.B.; Faro, C.J.; Carvalho, A.P.; Pires, E.V., Journal of Neurochemistry. 2112 - 2119. 5. 70. 1998. http://www.scopus.com/inward/record.url?eid=2-s2.0-0031980737&partnerID=MN8TOARS . Journal of Neurochemistry
Glutamate in life and death of retinal amacrine cells
Duarte, C.B.; Ferreira, I.L.; Santos, P.F.; Carvalho, A.L.; Agostinho, P.M.; Carvalho, A.P., General Pharmacology. 289 - 295. 3. 30. 1998. http://www.scopus.com/inward/record.url?eid=2-s2.0-0032033584&partnerID=MN8TOARS . 10.1016/S0306-3623(97)00360-1 . General Pharmacology
Photoacoustic measurements of porphyrin triplet-state quantum yields and singlet-oxygen efficiencies
Pineiro, M.; Carvalho, A.L.; Pereira, M.M.; Rocha Gonsalves, A.M.D'A.; Arnaut, L.G.; Formosinho, S.J.; Pineiro, M; et al, Chemistry - A European Journal. 2299 - 2307. 11. 4. 1998. http://www.scopus.com/inward/record.url?eid=2-s2.0-0031742441&partnerID=MN8TOARS . 10.1002/(SICI)1521-3765(19981102)4:11<2299::AID-CHEM2299>3.0.CO;2-H . Chemistry - A European Journal
In vivo and in vitro experiments show that betaxolol is a retinal neuroprotective agent
Osborne, N.N.; Cazevieille, C.; Carvalho, A.L.; Larsen, A.K.; Desantis, L.; Larson, A., Brain Research. 113 - 123. 1. 751. 1997. http://www.scopus.com/inward/record.url?eid=2-s2.0-0030894739&partnerID=MN8TOARS . 10.1016/S0006-8993(96)01393-5 . Brain Research
5 65 de 65 Publicações
Todos os projectos
Informação da exclusiva responsabilidade do investigador 18-04-2024 , a partir da plataforma CIÊNCIAVITAE.
2023/03/01 - 2024/08/31
MicroRNAs And Cognition in Longcovid: Exploratory Study
2022.04018.PTDC
Universidade de Coimbra
Financiadores: Fundação para a Ciência e a Tecnologia
2023/03/01 - 2024/08/31
A New TransSynaptic Bridge: Functional characterization of the NMDA receptor-Neurexin interaction
2022.05386.PTDC
Universidade de Coimbra
Financiadores: Fundação para a Ciência e a Tecnologia
2023/04/01 - 2026/03/31
Homeostatic plasticity defects in autism: insight from human mutations in the CNTNAP2 gene
202202-30-31
Co-Principal Investigator (Co-PI)
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Financiadores: Fundació la Marató de TV3
2021/01/01 - 2025/12/31
Center for Innovative Biomedicine and Biotechnology - Associate Laboratory
LA/P/0058/2020
Universidade de Coimbra
Financiadores: Fundação para a Ciência e a Tecnologia
2021 - 2024
Uncovering the molecular machinery responsible for cargo sorting in neuronal polarization
PTDC/BIA-CEL/2286/2020
Researcher
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Financiadores: Fundação para a Ciência e a Tecnologia
2021/12/01 - 2024/11/30
microSTRESS: Regulation of prefrontal cortical synaptic function and behavior by chronic stress-induced microRNA-186-5p
HR21-01077
Researcher
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Financiadores: Iniciativa Ibérica de Investigaçao e Inovaçao Biomédica, i4b, laCaixa Foundation/FCT
2021/01/01 - 2026/12/31
DYNABrain - DYNAMIC BRAIN FUNCTION: Towards the Understanding and Treatment of Brain Disorders
952422
Principal investigator
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Financiadores: European Commission
2020/12/01 - 2024/11/30
MStar - Potassium channel dysfunction in models of neurodevelopmental disorders
HR20-00904
Principal investigator
Financiadores: Iniciativa Ibérica de Investigaçao e Inovaçao Biomédica, i4b, laCaixa Foundation/FCT
2019/03 - 2023/08
Syn2Psy-Synaptic Dysfunction in Neuropsychiatric Disorders
H2020-MSCA-ITN-2018 (813986)
Principal investigator
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Financiadores: European Commission
2019/01/01 - 2019/12/31
CNC. IBILI
UID/NEU/04539/2019
Universidade de Coimbra Centro de Neurociências e Biologia Celular; Universidade de Coimbra; Universidade de Coimbra Instituto de Ciências Nucleares Aplicadas à Saúde; Universidade de Coimbra Instituto de Investigação Clínica e Biomédica de Coimbra
Financiadores: Fundação para a Ciência e a Tecnologia
2018/06 - 2021/05
Understanding the pathogenesis in CASPR2-antibody autoimmune synaptic encephalitis
PTDC/MED-NEU/29452/2017
Researcher
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Financiadores: Fundação para a Ciência e a Tecnologia
2018 - 2021
Molecular tools for Machado-Joseph disease: chaperoning toxic protein conformers in polyglutamine-containing proteins
PTDC/BIA-BFS/31173/2017
Researcher
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Financiadores: Fundação para a Ciência e a Tecnologia
2018/07 - 2021/06
COGNITIVE DISORDERS AS DEFECTS IN SYNAPTIC FUNCTION: INSIGHT FROM HUMAN MUTATIONS IN THE CACNG2 GENE
PTDC/MED-NEU/28541/2017
Principal investigator
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Financiadores: Fundação para a Ciência e a Tecnologia
2018 - 2021
Alternate SNAPs in neurotransmitter release: from molecular function to neurocognitive dysfunction
PTDC/BIA-CEL/29451/2017
Researcher
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Financiadores: Fundação para a Ciência e a Tecnologia
2017 - 2020
BrainHealth2020 - Early Detection, Neuromodulation and Advanced Therapies to Brain Disorders
CENTRO-01-0145-FEDER-000008
Universidade de Coimbra; Universidade de Coimbra Centro de Neurociências e Biologia Celular
Financiadores: European Regional Development Fund
2017 - 2020
BrainHealth2020
CENTRO-01-0145-FEDER-000008:BrainHealth 2020
Researcher
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Financiadores: European Regional Development Fund
2016 - 2018
A role for Contactin-associated proteins 1 and 2 in experience-dependent plasticity
PTDC/NEU-NMC/4888/2014
Researcher
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Financiadores: Fundação para a Ciência e a Tecnologia
2016 - 2018
BEHAVIOR ANALYSES OF MICE EXPRESSING A CACNG2 MUTATION ASSOCIATED WITH INTELLECTUAL DISABILITY
1530
Principal investigator
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Financiadores: Fondation Jérôme Lejeune
2015 - 2018
StrokeTherapy - Plataformas terapêuticas para acidentes vasculares cerebrais
3386
Researcher
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Financiadores: European Development Fund
2015 - 2018
Schizophrenia as a disruption of developmental homeostatic plasticity: a role for stargazin
23151
Principal investigator
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Financiadores: Brain and Behavior Research Foundation
2014/04/01 - 2015/09/30
A sabedoria do faminto: modulação por ghrelina da neurogénese e da sua relação com a memória
EXPL/NEU-SCC/1193/2013
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Financiadores: Fundação para a Ciência e a Tecnologia
2014/03/01 - 2015/09/30
Ageing@Coimbra: Um Centro de Co-localização na Rede Europeia de Conhecimento e Inovação para o Envelhecimento Saudável e Ativo
EIT-KIC/IVE/0043/2013
Universidade de Coimbra Centro de Neurociências e Biologia Celular; Administração Regional de Saúde do Centro IP; Universidade de Coimbra Instituto de Investigação Interdisciplinar; Universidade de Coimbra; Universidade de Coimbra Faculdade de Medicina
Financiadores: Fundação para a Ciência e a Tecnologia
2014/04 - 2015/09
Hunger wisdom: ghrelin modulation of adult neurogenesis and its relationship with memory
Provided by PTCRIS: 134218
Researcher
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Financiadores: Fundação para a Ciência e a Tecnologia
2014/03 - 2015/09
Ageing@Coimbra: A Co-location Centre in the European Knowledge and Innovation Network for Active and Healthy Ageing
Provided by PTCRIS: 135805
Researcher
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Financiadores: Fundação para a Ciência e a Tecnologia
2013/07 - 2015/09
A Novel Model for Schizophrenia: Defects in Stargazin-Mediated Homeostatic Plasticity.
Provided by PTCRIS: 125355
Principal investigator
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Financiadores: Fundação para a Ciência e a Tecnologia
2013/07 - 2015/11
Effects of the orexigenic peptide ghrelin on glutamatergic synaptic transmission
Provided by PTCRIS: 125955
Researcher
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Financiadores: Fundação para a Ciência e a Tecnologia
2011/01/01 - 2012/12/31
Strategic Project - LA 1 - 2011-2012
PEst-C/SAU/LA0001/2011
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Financiadores: Fundação para a Ciência e a Tecnologia
2011/01 - 2014/06
Regulation by phosphorylation of ataxin-3, the mutated protein in Machado Joseph Disease
Provided by PTCRIS: 110602
Principal investigator
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Financiadores: Fundação para a Ciência e a Tecnologia
2011/04 - 2013/06
Regulation of the stability of the messenger RNA for the GluR1 subunit of glutamate receptors
Provided by PTCRIS: 113738
Principal investigator
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Financiadores: Fundação para a Ciência e a Tecnologia
2010/09 - 2013/12
Molecular Mechanisms of Synaptic Traffic of Glutamate Receptors of the NMDA Type
Provided by PTCRIS: 99440
Principal investigator
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Financiadores: Fundação para a Ciência e a Tecnologia
2009/01 - 2011/12
Implementation of a Nacional Facility for DNA Microarrays: Phase II
Provided by PTCRIS: 64745
Researcher
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Financiadores: Fundação para a Ciência e a Tecnologia
2008/04 - 2011/03
Role of cortactin in the cellular trafficking of AMPA-type glutamate receptors
Provided by PTCRIS: 71789
Principal investigator
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Financiadores: Fundação para a Ciência e a Tecnologia
2008 - 2008
Molecular mechanisms coupling Ca2+-permeable AMPA receptors to excitotoxic signalling pathways
NA
Researcher
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Financiadores: Biogen Portugal
2007/06 - 2010/12
Regulation of AMPA receptors by hyperglycemia in the retina
Provided by PTCRIS: 71228
Researcher
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Financiadores: Fundação para a Ciência e a Tecnologia
2007/04 - 2010/04
Cleavage of the vesicular glutamate (VGLUT) and GABA (VGAT) transporters under excitotoxic conditions: identification of the cleavage sites and functional implications
Provided by PTCRIS: 65846
Researcher
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Financiadores: Fundação para a Ciência e a Tecnologia
2005/01 - 2007/12
Driving AMPA receptors into synapses: role of interacting proteins in the delivery of GluR4- and GluR2L-containing AMPA receptors
Provided by PTCRIS: 58955
Principal investigator
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Financiadores: Fundação para a Ciência e a Tecnologia
2005/06 - 2008/12
Molecular determinants of ataxin-3 aggregation and toxicity in Machado-Joseph´s disease
Provided by PTCRIS: 60156
Researcher
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Financiadores: Fundação para a Ciência e a Tecnologia
2003/03/01 - 2007
Regulation of the expression of ionotropic glutamate receptors by brain-derived neurotrophic factor (BDNF) in hippocampal neurons
info:eu-repo/grantAgreement/FCT/POCI/46466/PT
Researcher
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Financiadores: Fundação para a Ciência e a Tecnologia
2002 - 2004
Expression and functional characterization of naturally occuring truncated forms of AMPA-type glutamate receptor subunits
POCTI/MGI/43629/2001
Researcher
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Financiadores: Fundação para a Ciência e a Tecnologia
2000/11/01 - 2004
Protective effects of neurotrophins against glutamate toxicity in the hippocampus: intracellular signaling mechanisms
info:eu-repo/grantAgreement/FCT/POCI/32631/PT
Researcher
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Financiadores: Fundação para a Ciência e a Tecnologia
5 40 de 40 projetos
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