Luisa Cortes

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Investigador(a)

Coordenadora

Afiliação

CNC - Centro de Neurociências e Biologia Celular; III-UC - Instituto de Investigação Interdisciplinar; Universidade de Coimbra

Publicações

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Informação sobre artigos em revista, actualizada a 23-09-2021, a partir da plataforma CIÊNCIAVITAE.

Tacrine – Benzothiazoles: Novel class of potential multitarget anti-Alzheimers drugs dealing with cholinergic, amyloid and mitochondrial systems

Nepovimova, Eugenie; Svobodova, Lucie; Dolezal, Rafael; Hepnarova, Vendula; Junova, Lucie; Jun, Daniel; Korabecny, Jan; et al, Bioorganic Chemistry. 107. 2021. http://dx.doi.org/10.1016/j.bioorg.2020.104596 . 10.1016/j.bioorg.2020.104596 . Bioorganic Chemistry

Using amyloid autofluorescence as a biomarker for lysozyme aggregation inhibition

Jesus, Catarina S. H.; Soares, Helder T.; Piedade, Ana P.; Cortes, Luísa; Serpa, Carlos, The Analyst. 2021. http://dx.doi.org/10.1039/d0an02260h . 10.1039/d0an02260h . accepted The Analyst

Ligand-independent activity of the ghrelin receptor modulates AMPA receptor trafficking and supports memory formation

Luís F. Ribeiro; Tatiana Catarino; Mário Carvalho; Luísa Cortes; Sandra D. Santos; Patricio O. Opazo; Lyn Rosenbrier Ribeiro; et al, Science Signaling. 2021. https://doi.org/10.1126/scisignal.abb1953 . 10.1126/scisignal.abb1953 . Science Signaling

Constitutive ghrelin receptor activity modulates AMPA receptor traffic and supports memory formation

Ribeiro, L.F.; Catarino, Tatiana; Carvalho, Mário Jorge da Silva; Santos, Sandra; Cortes, Luisa; Opazo, P. O.; Ribeiro., L. R.; et al, bioRxiv . 2020. submitted bioRxiv

Ischaemia impacts TNT-mediated communication between cardiac cells

Daniela Batista-Almeida; Teresa Ribeiro-Rodrigues; Tânia Martins-Marques; Luisa Cortes; Manuel J. Antunes; Pedro E. Antunes; Lino Gonçalves; et al, Current Research in Cell Biology. 100001 - 100001. 1. 2020. https://doi.org/10.1016/j.crcbio.2020.04.001 . 10.1016/j.crcbio.2020.04.001 . Current Research in Cell Biology

Pollen Proteases Play Multiple Roles in Allergic Disorders

Cortes, Luisa, International Journal of Molecular Sciences. 2020. http://dx.doi.org/10.3390/ijms21103578 . 10.3390/ijms21103578 . International Journal of Molecular Sciences

Neuropeptide Y Enhances Progerin Clearance and Ameliorates the Senescent Phenotype of Human Hutchinson-Gilford Progeria Syndrome Cells

Aveleira, Célia A; Ferreira-Marques, Marisa; Cortes, Luísa; Valero, Jorge; Pereira, Dina; Pereira de Almeida, Luís; Cavadas, Cláudia, The Journals of Gerontology: Series A. 2020. http://dx.doi.org/10.1093/gerona/glz280 . 10.1093/gerona/glz280 . accepted The Journals of Gerontology: Series A

Calcium Signaling in Aging and Neurodegenerative Diseases 2019

Luísa Cortes; João Malva; Ana Cristina Rego; Cláudia F. Pereira, International Journal of Molecular Sciences. 1125 - 1125. 3. 21. 2020. https://doi.org/10.3390/ijms21031125 . 10.3390/ijms21031125 . International Journal of Molecular Sciences

BDNF increases synaptic NMDA receptor abundance by enhancing the local translation of Pyk2 in cultured hippocampal neurons

Pedro Afonso; Pasqualino De Luca; Rafael S. Carvalho; Luísa Cortes; Paulo Pinheiro; Barbara Oliveiros; Ramiro D. Almeida; Miranda Mele; Carlos B. Duarte, Science Signaling. eaav3577 - eaav3577. 586. 12. 2019. https://doi.org/10.1126/scisignal.aav3577 . 10.1126/scisignal.aav3577 . Science Signaling

Targeting of Cellular Organelles by Fluorescent Plasmid DNA Nanoparticles

Diana Costa; Carolina Costa; Margarida Caldeira; Luísa Cortes; João A. Queiroz; Carla Cruz, Biomacromolecules. 2928 - 2936. 9. 18. 2017. https://doi.org/10.1021/acs.biomac.7b00877 . 10.1021/acs.biomac.7b00877 . Biomacromolecules

Blunted dynamics of adenosine A2A receptors is associated with increased susceptibility to Candida albicans infection in the elderly.

Rodrigues L; Miranda IM; Andrade GM; Mota M; Cortes L; Rodrigues AG; Cunha RA; Gonçalves T, 2016. http://europepmc.org/abstract/med/27590517 . 10.18632/oncotarget.11760 .

Histamine induces microglia activation and dopaminergic neuronal toxicity via H1 receptor activation.

Rocha SM; Saraiva T; Cristóvão AC; Ferreira R; Santos T; Esteves M; Saraiva C; et al, 2016. http://europepmc.org/abstract/med/27260166 . 10.1186/s12974-016-0600-0 .

Neuropeptide Y stimulates autophagy in hypothalamic neurons.

Aveleira CA; Botelho M; Carmo-Silva S; Pascoal JF; Ferreira-Marques M; Nóbrega C; Cortes L; et al, 2015. http://europepmc.org/abstract/med/25775546 . 10.1073/pnas.1416609112 .

Modulation of Alternaria infectoria Cell Wall Chitin and Glucan Synthesis by Cell Wall Synthase Inhibitors.

Fernandes C; Anjos J; Walker LA; Silva BM; Cortes L; Mota M; Munro CA; Gow NA; Gonçalves T, 2014. http://europepmc.org/abstract/med/24614372 . 10.1128/AAC.02647-13 .

Neuropeptide y inhibits interleukin-1 beta-induced microglia motility

Ferreira, R.; Santos, T.; Cortes, L.; Cochaud, S.; Agasse, F.; Silva, A.P.; Xapelli, S.; Malva, J.O., Journal of Neurochemistry. 93 - 105. 1. 120. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-83855162714&partnerID=MN8TOARS . 10.1111/j.1471-4159.2011.07541.x . Journal of Neurochemistry

Combined effects of singlet oxygen and hydroxyl radical in photodynamic therapy with photostable bacteriochlorins: Evidence from intracellular fluorescence and increased photodynamic efficacy in vitro

Da¸browski, J.M.; Arnaut, L.G.; Pereira, M.M.; Urbanska, K.; Simões, S.; Stochel, G.; Cortes, L., Free Radical Biology and Medicine. 1188 - 1200. 7. 52. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84857920394&partnerID=MN8TOARS . 10.1016/j.freeradbiomed.2011.12.027 . Free Radical Biology and Medicine

Presynaptic CB1 cannabinoid receptors control frontocortical serotonin and glutamate release - Species differences

Ferreira, S.G.; Teixeira, F.M.; Garção, P.; Agostinho, P.; Ledent, C.; Cortes, L.; MacKie, K.; Köfalvi, A., Neurochemistry International. 219 - 226. 2. 61. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84863463752&partnerID=MN8TOARS . 10.1016/j.neuint.2012.05.009 . Neurochemistry International

Valosin-Containing Protein (VCP/p97) Is an Activator of Wild-Type Ataxin-3

Laço, M.N.; Cortes, L.; Travis, S.M.; Paulson, H.L.; Rego, A.C., PLoS ONE. 9. 7. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84866103154&partnerID=MN8TOARS . 10.1371/journal.pone.0043563 . PLoS ONE

Mitochondrial metabolism in Parkinson's disease impairs quality control autophagy by hampering microtubule-dependent traffic

Arduíno, D.M.; Esteves, A.R.; Cortes, L.; Silva, D.F.; Patel, B.; Grazina, M.; Swerdlow, R.H.; Oliveira, C.R.; Cardoso, S.M., Human Molecular Genetics. 4680 - 4702. 21. 21. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84867828156&partnerID=MN8TOARS . 10.1093/hmg/dds309 . Human Molecular Genetics

Polymeric nanoparticles to control the differentiation of neural stem cells in the subventricular zone of the brain

Santos, T.; Ferreira, R.; Maia, J.; Agasse, F.; Xapelli, S.; Cortes, L.; Bragancia, J.; et al, ACS Nano. 10463 - 10474. 12. 6. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84871596644&partnerID=MN8TOARS . 10.1021/nn304541h . ACS Nano

Pollen proteases compromise the airway epithelial barrier through degradation of transmembrane adhesion proteins and lung bioactive peptides

Vinhas, R.; Cortes, L.; Cardoso, I.; Mendes, V.M.; Manadas, B.; Todo-Bom, A.; Pires, E.; Veríssimo, P., Allergy: European Journal of Allergy and Clinical Immunology. 1088 - 1098. 8. 66. 2011. http://www.scopus.com/inward/record.url?eid=2-s2.0-79960015037&partnerID=MN8TOARS . 10.1111/j.1398-9995.2011.02598.x . Allergy: European Journal of Allergy and Clinical Immunology

Functional identification of cell phenotypes differentiating from mice retinal neurospheres using single cell calcium imaging.

De Melo Reis, R.A.; Schitine, C.S.; Köfalvi, A.; Grade, S.; Cortes, L.; Gardino, P.F.; Malva, J.O.; de Mello, F.G., Cellular and molecular neurobiology. 835 - 846. 6. 31. 2011. http://www.scopus.com/inward/record.url?eid=2-s2.0-84856384867&partnerID=MN8TOARS . Cellular and molecular neurobiology

Neuropeptide Y inhibits interleukin-1ß-induced phagocytosis by microglial cells

Ferreira, R.; Santos, T.; Viegas, M.; Cortes, L.; Bernardino, L.; Vieira, O.V.; Malva, J.O., Journal of Neuroinflammation. 8. 2011. http://www.scopus.com/inward/record.url?eid=2-s2.0-82455168238&partnerID=MN8TOARS . 10.1186/1742-2094-8-169 . Journal of Neuroinflammation

Controlling the neuronal differentiation of stem cells by the intracellular delivery of retinoic acid-loaded nanoparticles

Maia, J.; Santos, T.; Aday, S.; Agasse, F.; Cortes, L.; Malva, J.O.; Bernardino, L.; Ferreira, L., ACS Nano. 97 - 106. 1. 5. 2011. http://www.scopus.com/inward/record.url?eid=2-s2.0-79955113748&partnerID=MN8TOARS . 10.1021/nn101724r . ACS Nano

Functional Identification of Cell Phenotypes Differentiating from Mice Retinal Neurospheres Using Single Cell Calcium Imaging

De Melo Reis, R.A.; Schitine, C.S.; Kofalvi, A.; Grade, S.; Cortes, L.; Gardino, P.F.; Malva, J.O.; de Mello, F.G., Cellular and Molecular Neurobiology. 1 - 12. 2011. http://www.scopus.com/inward/record.url?eid=2-s2.0-79952606231&partnerID=MN8TOARS . 10.1007/s10571-011-9673-6 . Cellular and Molecular Neurobiology

The angiogenic factor angiopoietin-1 is a proneurogenic peptide on subventricular zone stem/progenitor cells

Rosa, A.I.; Gonçalves, J.; Cortes, L.; Bernardino, L.; Malva, J.O.; Agasse, F., Journal of Neuroscience. 4573 - 4584. 13. 30. 2010. http://www.scopus.com/inward/record.url?eid=2-s2.0-77950633340&partnerID=MN8TOARS . 10.1523/JNEUROSCI.5597-09.2010 . Journal of Neuroscience

Functional identification of neural stem cell-derived oligodendrocytes by means of calcium transients elicited by thrombin

Grade, S.; Agasse, F.; Bernardino, L.; Silva, C.G.; Cortes, L.; Malva, J.O., Rejuvenation Research. 27 - 37. 1. 13. 2010. http://www.scopus.com/inward/record.url?eid=2-s2.0-77949493309&partnerID=MN8TOARS . 10.1089/rej.2009.0889 . Rejuvenation Research

Neuropeptide y modulation of interleukin-1ß (IL-1ß)-induced nitric oxide production in microglia

Ferreira, R.; Xapelli, S.; Santos, T.; Silva, A.P.; Cristóvão, A.; Cortes, L.; Malva, J.O., Journal of Biological Chemistry. 41921 - 41934. 53. 285. 2010. http://www.scopus.com/inward/record.url?eid=2-s2.0-78650658398&partnerID=MN8TOARS . 10.1074/jbc.M110.164020 . Journal of Biological Chemistry

Nucleocytoplasmic Shuttling Activity of Ataxin-3

Macedo-Ribeiro, Sandra; Cortes, Luísa; Maciel, Patrícia; Carvalho, Ana Luísa, PLoS ONE. 6. 4. 2009. http://dx.doi.org/10.1371/journal.pone.0005834 . 10.1371/journal.pone.0005834 . PLoS ONE

NEDD8: A new ataxin-3 interactor

Ferro, A.; Carvalho, A.L.; Teixeira-Castro, A.; Almeida, C.; Tomé, R.J.; Cortes, L.; Rodrigues, A.-J.; et al, Biochimica et Biophysica Acta - Molecular Cell Research. 1619 - 1627. 11. 1773. 2007. http://www.scopus.com/inward/record.url?eid=2-s2.0-35548938484&partnerID=MN8TOARS . 10.1016/j.bbamcr.2007.07.012 . Biochimica et Biophysica Acta - Molecular Cell Research

Purification of a novel aminopeptidase from the pollen of Parietaria judaica that alters epithelial integrity and degrades neuropeptides

Cortes, L.; Carvalho, A.L.; Todo-Bom, A.; Faro, C.; Pires, E.; Veríssimo, P., Journal of Allergy and Clinical Immunology. 878 - 884. 4. 118. 2006. http://www.scopus.com/inward/record.url?eid=2-s2.0-33749349447&partnerID=MN8TOARS . 10.1016/j.jaci.2006.05.029 . Journal of Allergy and Clinical Immunology

Towards a structural understanding of the fibrillization pathway in Machado-Joseph's disease: Trapping early oligomers of non-expanded ataxin-3

Gales, L.; Cortes, L.; Almeida, C.; Melo, C.V.; Costa, M.D.C.; Maciel, P.; Clarke, D.T.; et al, Journal of Molecular Biology. 642 - 654. 3. 353. 2005. http://www.scopus.com/inward/record.url?eid=2-s2.0-26244434741&partnerID=MN8TOARS . 10.1016/j.jmb.2005.08.061 . Journal of Molecular Biology

Identification of the pgmG gene, encoding a bifunctional protein with phosphoglucomutase and phosphomannomutase activities, in the gellan gum- producing strain Sphingomonas paucimobilis ATCC 31461

Videira, P.A.; Cortes, L.L.; Fialho, A.M.; Sá-Correia, I., Applied and Environmental Microbiology. 2252 - 2258. 5. 66. 2000. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034016761&partnerID=MN8TOARS . 10.1128/AEM.66.5.2252-2258.2000 . Applied and Environmental Microbiology

Identification and proteolytic processing of procardosin A

Ramalho-Santos, M.; Verissimo, P.; Cortes, L.; Samyn, B.; Beeumen, J.V.; Pires, E.; Faro, C., European Journal of Biochemistry. 133 - 138. 1. 255. 1998. http://www.scopus.com/inward/record.url?eid=2-s2.0-0032127477&partnerID=MN8TOARS . 10.1046/j.1432-1327.1998.2550133.x . European Journal of Biochemistry

Todos os projectos

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Informação da exclusiva responsabilidade do investigador 23-09-2021 , a partir da plataforma CIÊNCIAVITAE.

2020/11/16 - 2021/07/15

TecniCOV –Desenvolvimentode testes rápidos para monitorização de anticorpos em soro e saliva

TecniCOV, número 69745

Researcher

Universidade de Coimbra

Financiadores: Autoridade de Gestão do Programa Operacional Competitividade e Internacionalização

2016/01 - 2019/12

Imaging Gene Therapy in the Brain

Provided by PTCRIS: 139557

Principal investigator

Universidade de Coimbra Centro de Neurociências e Biologia Celular

Financiadores: Fundação para a Ciência e a Tecnologia

2014/04/01 - 2015/09/30

Hunger wisdom: ghrelin modulation of adult neurogenesis and its relationship with memory

EXPL/NEU-SCC/1193/2013

Researcher

Universidade de Coimbra Centro de Neurociências e Biologia Celular

Financiadores: Fundação para a Ciência e a Tecnologia

2013/07/01 - 2015/11/30

Effects of the orexigenic peptide ghrelin on glutamatergic synaptic transmission

PTDC/NEU-NMC/1098/2012

Researcher

Universidade de Coimbra Centro de Neurociências e Biologia Celular

Financiadores: Fundação para a Ciência e a Tecnologia

2012 - 2012

Effect of the orexigenic peptide ghrelin on AMPA receptors levels at the synapse

EMBO Short-term fellowship - ASTF 126 2012

Financiadores: N/A

2011/01/01 - 2014/06/30

Regulation by phosphorylation of ataxin-3, the mutated protein in Machado Joseph Disease

PTDC/SAU-NMC/110602/2009

Researcher

Universidade de Coimbra Centro de Neurociências e Biologia Celular; Universidade do Porto Instituto de Biologia Molecular e Celular; Universidade do Minho

Financiadores: Fundação para a Ciência e a Tecnologia

2010/03/17 - 2012/07/31

Mapping the metabolic and neuromodulator role of insulin in the hippocampus

PTDC/SAU-OSM/105663/2008

Researcher

Universidade de Coimbra Centro de Neurociências e Biologia Celular

Financiadores: Fundação para a Ciência e a Tecnologia

2010/03/17 - 2012/06/16

Demonstrating that A2A adenosine receptors control glutamatergic synaptic plasticity through CB1 cannabinoid receptors in the striatum, thus providing attracting therapeutic targets

PTDC/SAU-NEU/100729/2008

Researcher

Universidade de Coimbra Centro de Neurociências e Biologia Celular

Financiadores: Fundação para a Ciência e a Tecnologia

2010/04/01 - 2013/06/30

Role of intercellular communication between endothelial and stem cells in stemness and neurogenesis: new targets for brain repair therapies.

PTDC/SAU-NEU/101783/2008

Researcher

Universidade de Coimbra Centro de Neurociências e Biologia Celular

Financiadores: Fundação para a Ciência e a Tecnologia

2010/04/01 - 2013/03/31

Histamine versus antihistamines: new modulators of neurogenesis?

PTDC/SAU-NEU/104415/2008

Researcher

Universidade de Coimbra Centro de Neurociências e Biologia Celular

Financiadores: Fundação para a Ciência e a Tecnologia

2010/04/01 - 2013/07/15

Effect of caffeine and adenosine A2A receptors on stress response: role of adrenal gland modulation

PTDC/SAU-NEU/108110/2008

Researcher

Universidade de Coimbra Centro de Neurociências e Biologia Celular

Financiadores: Fundação para a Ciência e a Tecnologia

2008/04/01 - 2012/03/31

PROFILING ATAXIN-3 UBIQUITIN PROTEASE ACTIVITY: A BIOCHEMICAL AND STRUCTURAL APPROACH

PTDC/BIA-PRO/70455/2006

Research Fellow

Financiadores: Fundação para a Ciência e a Tecnologia

2008/05/23 - 2012/05/22

Pollen proteases, role in allergic disorders

PTDC/SAU-ESA/72571/2006

Researcher

Universidade de Coimbra Centro de Neurociências e Biologia Celular; Universidade de Coimbra

Financiadores: Fundação para a Ciência e a Tecnologia

2005/06/01 - 2008/12/31

Molecular determinants of ataxin-3 aggregation and toxicity in Machado-Joseph´s disease

POCI/SAU-MMO/60156/2004

Research Fellow

Universidade do Porto Instituto de Biologia Molecular e Celular; Universidade de Coimbra Centro de Neurociências e Biologia Celular

Financiadores: Fundação para a Ciência e a Tecnologia

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